Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor

Nature Biotechnology

Volumn 29, Issue 7, 2011, Pages 653-658

  Bisson, Nicolas ^a   James, D Andrew ^a,d   Ivosev, Gordana ^b   Tate, Stephen A ^b   Bonner, Ron ^b   Taylor, Lorne ^a   Pawson, Tony ^a,c  

^a MOUNT SINAI HOSPITAL   (Canada)

^b MDS SCIEX   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d Sanofi Pasteur   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEINS; CELLULAR FUNCTION; CELLULAR RESPONSE; HUB PROTEINS; PROTEIN COMPLEXES; PROTEIN INTERACTION; PROTEIN INTERACTION NETWORKS; PROTEIN-PROTEIN INTERACTIONS; QUANTITATIVE DATA; REACTION MONITORING; SELECTED REACTION MONITORING; SIGNALING PATHWAYS; TIME-DEPENDENT NETWORKS;

COMPLEXATION; MASS SPECTROMETRY; SIGNALING;

PROTEINS;

GROWTH FACTOR; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; HYBRID PROTEIN; PROTEIN SH2; PROTEIN SH3;

AFFINITY PURIFICATION SELECTED REACTION MONITORING; ARTICLE; BINDING AFFINITY; CELL FUNCTION; CELL STIMULATION; CELL STRAIN HEK293; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DATABASE; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SIGNAL TRANSDUCTION;

CHROMATOGRAPHY, AFFINITY; GRB2 ADAPTOR PROTEIN; HEK293 CELLS; HUMANS; MASS SPECTROMETRY; PROTEIN INTERACTION MAPPING; SIGNAL TRANSDUCTION;

EID: 79960245388     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.1905     Document Type: Article

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