Detection of intestinal cancer by local, Topical application of a quenched fluorescence probe for cysteine cathepsins

Chemistry and Biology

Volumn 22, Issue 1, 2015, Pages 148-158

  Segal, Ehud ^a   Prestwood, Tyler R ^a   Van Der Linden, Wouter A ^a   Carmi, Yaron ^a   Bhattacharya, Nupur ^a   Withana, Nimali ^a   Verdoes, Martijn ^a,b   Habtezion, Aida ^a   Engleman, Edgar G ^a   Bogyo, Matthew ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BMV 109; CATHEPSIN; CONTRAST MEDIUM; CYSTEINE; FLUORESCENT DYE; UNCLASSIFIED DRUG; APC PROTEIN; CARBOCYANINE; CYANINE DYE 5;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLONOSCOPY; COLORECTAL CARCINOMA; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; EARLY DIAGNOSIS; FLUORESCENCE; GASTROINTESTINAL DYSPLASIA; GENETIC MODEL; HUMAN; HUMAN TISSUE; INTESTINE CANCER; INTESTINE POLYP; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIVITY AND SPECIFICITY; ANIMAL; C57BL MOUSE; CHEMISTRY; DISEASE MODEL; ENZYME ACTIVE SITE; GENETICS; IMMUNOHISTOCHEMISTRY; INTESTINAL NEOPLASMS; METABOLISM; PATHOLOGY; POLYPS;

MUS;

ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; CARBOCYANINES; CATALYTIC DOMAIN; CATHEPSINS; COLONOSCOPY; DISEASE MODELS, ANIMAL; FLUORESCENT DYES; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINAL NEOPLASMS; MALE; MICE; MICE, INBRED C57BL; POLYPS; SENSITIVITY AND SPECIFICITY;

EID: 84921466095     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2014.11.008     Document Type: Article

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