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Volumn 43, Issue 2, 2015, Pages 232-237

Effects of local application of simvastatin on bone regeneration in femoral bone defects in rabbit

Author keywords

Bone defects; Bone regeneration; Carriers; Simvastatin

Indexed keywords

CALCIUM SULFATE; COLLAGEN SPONGE; HYDROXYAPATITE; SIMVASTATIN; ARTIFICIAL MEMBRANE; BIO-OSS; BIOMATERIAL; COLLAGEN; DRUG CARRIER; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MINERAL;

EID: 84921436905     PISSN: 10105182     EISSN: 18784119     Source Type: Journal    
DOI: 10.1016/j.jcms.2014.11.011     Document Type: Article
Times cited : (26)

References (46)
  • 1
    • 59649102438 scopus 로고    scopus 로고
    • Local application of statin promotes bone repair through the suppression of osteoclasts and the enhancement of osteoblasts at bone healing sites in rats
    • Y. Ayukawa, E. Yasukawa, Y. Moriyama, Y. Ogino, H. Wada, and I. Atsuta Local application of statin promotes bone repair through the suppression of osteoclasts and the enhancement of osteoblasts at bone healing sites in rats Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107 3 2008 336 342
    • (2008) Oral Surg Oral Med Oral Pathol Oral Radiol Endod , vol.107 , Issue.3 , pp. 336-342
    • Ayukawa, Y.1    Yasukawa, E.2    Moriyama, Y.3    Ogino, Y.4    Wada, H.5    Atsuta, I.6
  • 2
    • 21344462154 scopus 로고    scopus 로고
    • The effect of simvastatin on the proliferation and differentiation of human bone marrow stromal cells
    • K.H. Baek, W.Y. Lee, K.W. Oh, H.J. Tae, J.M. Lee, and E.J. Lee The effect of simvastatin on the proliferation and differentiation of human bone marrow stromal cells J Korean Med Sci 20 3 2005 438 444
    • (2005) J Korean Med Sci , vol.20 , Issue.3 , pp. 438-444
    • Baek, K.H.1    Lee, W.Y.2    Oh, K.W.3    Tae, H.J.4    Lee, J.M.5    Lee, E.J.6
  • 4
    • 33748805769 scopus 로고    scopus 로고
    • Synthesis and characterization of a fluvastatin-releasing hydrogel delivery system to modulate hMSC differentiation and function for bone regeneration
    • D.S. Benoit, C.R. Nuttelman, S.D. Collins, and K.S. Anseth Synthesis and characterization of a fluvastatin-releasing hydrogel delivery system to modulate hMSC differentiation and function for bone regeneration Biomaterials 27 36 2006 6102 6110
    • (2006) Biomaterials , vol.27 , Issue.36 , pp. 6102-6110
    • Benoit, D.S.1    Nuttelman, C.R.2    Collins, S.D.3    Anseth, K.S.4
  • 5
    • 0035433429 scopus 로고    scopus 로고
    • An evaluation of bone induction delivery materials in conjunction with root-form implant placement
    • P.J. Boyne, and S. Shabahang An evaluation of bone induction delivery materials in conjunction with root-form implant placement Int J Periodontics Restorative Dent 21 2001 333 343
    • (2001) Int J Periodontics Restorative Dent , vol.21 , pp. 333-343
    • Boyne, P.J.1    Shabahang, S.2
  • 7
    • 56549100353 scopus 로고    scopus 로고
    • Safety of statins
    • W.V. Brown Safety of statins Curr Opin Lipidol 19 6 2008 558 562
    • (2008) Curr Opin Lipidol , vol.19 , Issue.6 , pp. 558-562
    • Brown, W.V.1
  • 8
    • 0033393022 scopus 로고    scopus 로고
    • Low-density lipoprotein-independent effects of statins
    • J. Davignon, and R. Laaksonen Low-density lipoprotein-independent effects of statins Curr Opin Lipidol 10 1999 543 559
    • (1999) Curr Opin Lipidol , vol.10 , pp. 543-559
    • Davignon, J.1    Laaksonen, R.2
  • 10
    • 33746972807 scopus 로고    scopus 로고
    • Calcium phosphate cements as bone drug delivery systems: A review
    • M.P. Ginebra, T. Traykova, and J.A. Planell Calcium phosphate cements as bone drug delivery systems: a review J Control Release 113 2006 102 110
    • (2006) J Control Release , vol.113 , pp. 102-110
    • Ginebra, M.P.1    Traykova, T.2    Planell, J.A.3
  • 12
    • 0031107805 scopus 로고    scopus 로고
    • A feasibility study evaluating rhBMP-2/absorbable collagen sponge device for local alveolar ridge preservation or augmentation
    • T.H. Howell, J. Fiorellini, A. Jones, M. Alder, P. Nummikoski, and M. Lazaro A feasibility study evaluating rhBMP-2/absorbable collagen sponge device for local alveolar ridge preservation or augmentation Int J Periodontics Restorative Dent 17 1997 124 139
    • (1997) Int J Periodontics Restorative Dent , vol.17 , pp. 124-139
    • Howell, T.H.1    Fiorellini, J.2    Jones, A.3    Alder, M.4    Nummikoski, P.5    Lazaro, M.6
  • 13
    • 36148999845 scopus 로고    scopus 로고
    • A comparison between the effects of hydrophobic and hydrophilic statins on osteoclast function in vitro and ovariectomy-induced bone loss in-vivo
    • A. Hughes, M.J. Rogers, Al Idris, and J.C. Crockett A comparison between the effects of hydrophobic and hydrophilic statins on osteoclast function in vitro and ovariectomy-induced bone loss in-vivo Calcif Tissue Int 81 5 2007 403 413
    • (2007) Calcif Tissue Int , vol.81 , Issue.5 , pp. 403-413
    • Hughes, A.1    Rogers, M.J.2    Idris, A.3    Crockett, J.C.4
  • 14
    • 0035018439 scopus 로고    scopus 로고
    • Hyaluronan supports recombinant human bone morphogenetic protein-2 induced bone reconstruction of advanced alveolar ridge defects in dogs: A pilot study
    • D.R. Hunt, S.A. Jovanovich, U.M.E. Wikesjo, J.M. Wozney, and G.W. Bernard Hyaluronan supports recombinant human bone morphogenetic protein-2 induced bone reconstruction of advanced alveolar ridge defects in dogs: a pilot study J Periodontol 72 2000 651 658
    • (2000) J Periodontol , vol.72 , pp. 651-658
    • Hunt, D.R.1    Jovanovich, S.A.2    Wikesjo, U.M.E.3    Wozney, J.M.4    Bernard, G.W.5
  • 15
    • 0344010709 scopus 로고    scopus 로고
    • The effect of rh-BMP-2 on guided bone regeneration in humans. A randomized, controlled clinical and histomorphometric study
    • R.E. Jang, R. Glauser, P. Scharer, C.H.F. Hammerle, and F.E. Weber The effect of rh-BMP-2 on guided bone regeneration in humans. A randomized, controlled clinical and histomorphometric study Clin Oral Implants Res 14 2003 556 568
    • (2003) Clin Oral Implants Res , vol.14 , pp. 556-568
    • Jang, R.E.1    Glauser, R.2    Scharer, P.3    Hammerle, C.H.F.4    Weber, F.E.5
  • 16
    • 0032487138 scopus 로고    scopus 로고
    • The effect of recombinant human bone morphogenetic protein-2 on the integration of porous hydroxyapatite implants with bone
    • J.A. Koempel, B.S. Patt, K. O'Grady, J. Wozney, and D.M. Toriumi The effect of recombinant human bone morphogenetic protein-2 on the integration of porous hydroxyapatite implants with bone J Biomed Mater Res 41 1998 359 363
    • (1998) J Biomed Mater Res , vol.41 , pp. 359-363
    • Koempel, J.A.1    Patt, B.S.2    O'Grady, K.3    Wozney, J.4    Toriumi, D.M.5
  • 17
    • 0036166394 scopus 로고    scopus 로고
    • Properties of osteoconductive biomaterials: Calcium phosphates
    • R.Z. LeGeros Properties of osteoconductive biomaterials: calcium phosphates Clin Orthop Relat Res 395 2002 81 98
    • (2002) Clin Orthop Relat Res , vol.395 , pp. 81-98
    • Legeros, R.Z.1
  • 18
    • 79952167520 scopus 로고    scopus 로고
    • Influence of the association between simvastatin and demineralized bovine bone matrix on bone repair in rats
    • C.E. Lima, J.C. Calixto, and A.L. Andinder Influence of the association between simvastatin and demineralized bovine bone matrix on bone repair in rats Braz Oral Res 25 1 2011 42 48
    • (2011) Braz Oral Res , vol.25 , Issue.1 , pp. 42-48
    • Lima, C.E.1    Calixto, J.C.2    Andinder, A.L.3
  • 19
    • 36249030519 scopus 로고    scopus 로고
    • The effect of simvastatin on bone formation and ceramic resorption in a peri-implant defect model
    • B. Ma, S.A. Clarke, R.A. Brooks, and N. Rushton The effect of simvastatin on bone formation and ceramic resorption in a peri-implant defect model Acta Biomater 4 1 2008 149 155
    • (2008) Acta Biomater , vol.4 , Issue.1 , pp. 149-155
    • Ma, B.1    Clarke, S.A.2    Brooks, R.A.3    Rushton, N.4
  • 20
    • 0034805319 scopus 로고    scopus 로고
    • Simvastatin promotes osteoblast differentiation and mineralization in MC3T3-E1 cells
    • T. Maeda, A. Matsunuma, T. Kawane, and N. Horiuchi Simvastatin promotes osteoblast differentiation and mineralization in MC3T3-E1 cells Biochem Biophys Res Commun 280 2001 874 877
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 874-877
    • Maeda, T.1    Matsunuma, A.2    Kawane, T.3    Horiuchi, N.4
  • 21
    • 0037318567 scopus 로고    scopus 로고
    • Statins augment vascular endothelial growth factor expression in osteoblastic cells via inhibition of protein prenylation
    • T. Maeda, T. Kawane, and N. Horiuchi Statins augment vascular endothelial growth factor expression in osteoblastic cells via inhibition of protein prenylation Endocrinology 144 2003 681 692
    • (2003) Endocrinology , vol.144 , pp. 681-692
    • Maeda, T.1    Kawane, T.2    Horiuchi, N.3
  • 24
    • 0033984436 scopus 로고    scopus 로고
    • Current perspectives on statins
    • D.J. Marou, S. Fazio, and M.F. Linton Current perspectives on statins Circulation 101 2000 207 213
    • (2000) Circulation , vol.101 , pp. 207-213
    • Marou, D.J.1    Fazio, S.2    Linton, M.F.3
  • 26
    • 0033521078 scopus 로고    scopus 로고
    • Stimulation of bone formation in vitro and in rodents by statins
    • G. Mundy, R. Garrett, S. Harris, J. Chan, D. Chen, and G. Rossini Stimulation of bone formation in vitro and in rodents by statins Science 286 1999 1946 1949
    • (1999) Science , vol.286 , pp. 1946-1949
    • Mundy, G.1    Garrett, R.2    Harris, S.3    Chan, J.4    Chen, D.5    Rossini, G.6
  • 27
    • 34548499895 scopus 로고    scopus 로고
    • Bone formation with the combination of simvastatin and calcium sulphate in critical sized rat calvarial defect
    • M. Nyan, D. Sato, M. Oda, T. Machida, H. Kobayashi, and T. Nakamura Bone formation with the combination of simvastatin and calcium sulphate in critical sized rat calvarial defect J Pharmacol Sci 104 2007 384 386
    • (2007) J Pharmacol Sci , vol.104 , pp. 384-386
    • Nyan, M.1    Sato, D.2    Oda, M.3    Machida, T.4    Kobayashi, H.5    Nakamura, T.6
  • 28
    • 60049090602 scopus 로고    scopus 로고
    • Effects of the combination with alpha-tricalcium phosphate and simvastatin on bone regeneration
    • M. Nyan, D. Sato, H. Kihara, T. Machida, K. Ohya, and S. Kasugai Effects of the combination with alpha-tricalcium phosphate and simvastatin on bone regeneration Clin Oral Implants Res 20 3 2009 280 287
    • (2009) Clin Oral Implants Res , vol.20 , Issue.3 , pp. 280-287
    • Nyan, M.1    Sato, D.2    Kihara, H.3    Machida, T.4    Ohya, K.5    Kasugai, S.6
  • 29
    • 0242408213 scopus 로고    scopus 로고
    • Collagen as a carrier for on-site delivery of antibacterial drugs
    • Z. Ruszczak, and W. Friess Collagen as a carrier for on-site delivery of antibacterial drugs Adv Drug Deliv Rev 55 12 2003 1679 1698
    • (2003) Adv Drug Deliv Rev , vol.55 , Issue.12 , pp. 1679-1698
    • Ruszczak, Z.1    Friess, W.2
  • 30
    • 33845878147 scopus 로고    scopus 로고
    • Repair of 20 mm long rabbit radial bone defects using BMP-derived peptide combined with an a-tricalcium phosphate scaffold
    • A. Saito, Y. Suzuki, M. Kitamura, S. Ogata, Y. Yoshihara, and S. Masuda Repair of 20 mm long rabbit radial bone defects using BMP-derived peptide combined with an a-tricalcium phosphate scaffold J Biomed Mater Res 77A 2006 700 706
    • (2006) J Biomed Mater Res , vol.77 A , pp. 700-706
    • Saito, A.1    Suzuki, Y.2    Kitamura, M.3    Ogata, S.4    Yoshihara, Y.5    Masuda, S.6
  • 31
  • 32
    • 34548515391 scopus 로고    scopus 로고
    • Local application of simvastatin to rat incisor socket: Carrier dependent effect on bone augmentation
    • D. Sato, K. Nishimura, T. Ishioka, H. Hondo, S. Kuroda, and S. Kasugai Local application of simvastatin to rat incisor socket: carrier dependent effect on bone augmentation J Oral Tiss Engin 2 2 2005 81 85
    • (2005) J Oral Tiss Engin , vol.2 , Issue.2 , pp. 81-85
    • Sato, D.1    Nishimura, K.2    Ishioka, T.3    Hondo, H.4    Kuroda, S.5    Kasugai, S.6
  • 34
    • 0042666802 scopus 로고    scopus 로고
    • Simvastatin induces osteoblastic differentiation and inhibits adipocytic differentiation in mouse bone marrow stromal cells
    • C. Song, Z. Guo, Q. Ma, Z. Chen, Z. Liu, and H. Jia Simvastatin induces osteoblastic differentiation and inhibits adipocytic differentiation in mouse bone marrow stromal cells Biochem Biophys Res Commun 308 3 2003 458 462
    • (2003) Biochem Biophys Res Commun , vol.308 , Issue.3 , pp. 458-462
    • Song, C.1    Guo, Z.2    Ma, Q.3    Chen, Z.4    Liu, Z.5    Jia, H.6
  • 35
    • 0037214223 scopus 로고    scopus 로고
    • The ability of statins to inhibit bone resorption is directly related to their inhibitory effect on HMG-CoA-reductase activity
    • A. Staal, J.C. Frith, M.H. French, J. Swartz, T. Gungor, and T.W. Harrity The ability of statins to inhibit bone resorption is directly related to their inhibitory effect on HMG-CoA-reductase activity J Bone Miner Res 18 1 2003 88 96
    • (2003) J Bone Miner Res , vol.18 , Issue.1 , pp. 88-96
    • Staal, A.1    Frith, J.C.2    French, M.H.3    Swartz, J.4    Gungor, T.5    Harrity, T.W.6
  • 37
    • 0034685669 scopus 로고    scopus 로고
    • Compactin and simvastatin, but not pravastatin, induce bone morphogenetic protein-2 in human osteosarcoma cells
    • M. Sugiyama, T. Kodama, K. Konishi, K. Abe, S. Asami, and S. Oikawa Compactin and simvastatin, but not pravastatin, induce bone morphogenetic protein-2 in human osteosarcoma cells Biochem Biophys Res Commun 271 2000 688 692
    • (2000) Biochem Biophys Res Commun , vol.271 , pp. 688-692
    • Sugiyama, M.1    Kodama, T.2    Konishi, K.3    Abe, K.4    Asami, S.5    Oikawa, S.6
  • 39
    • 0025950741 scopus 로고
    • Mandibular reconstruction with a recombinant bone-inducing factor. Functional, histologic, and biomechanical evaluation
    • D.M. Toriumi, H.S. Kotler, D.P. Luxenberg, M.E. Holtrop, and E.A. Wang Mandibular reconstruction with a recombinant bone-inducing factor. Functional, histologic, and biomechanical evaluation Arch Otolaryngol Head Neck Surg 117 1991 1101 1112
    • (1991) Arch Otolaryngol Head Neck Surg , vol.117 , pp. 1101-1112
    • Toriumi, D.M.1    Kotler, H.S.2    Luxenberg, D.P.3    Holtrop, M.E.4    Wang, E.A.5
  • 40
    • 0038519784 scopus 로고    scopus 로고
    • Rh-BMP-2/alphaBSM induces significant vertical alveolar ridge augmentation and dental implant osseointegration
    • U.M. Wikesjo, R.G. Sorensen, A. Kinosita, and J.M. Wozney Rh-BMP-2/alphaBSM induces significant vertical alveolar ridge augmentation and dental implant osseointegration Clin Implant Dent Relat Res 4 2002 174 182
    • (2002) Clin Implant Dent Relat Res , vol.4 , pp. 174-182
    • Wikesjo, U.M.1    Sorensen, R.G.2    Kinosita, A.3    Wozney, J.M.4
  • 41
    • 0141725406 scopus 로고    scopus 로고
    • Statin collagen grafts used to repair bone defects in the parietal bone of rabbits
    • R.W.K. Wong, and A.B.M. Rabie Statin collagen grafts used to repair bone defects in the parietal bone of rabbits Br J Oral Maxillofac Surg 41 2003 244 248
    • (2003) Br J Oral Maxillofac Surg , vol.41 , pp. 244-248
    • Wong, R.W.K.1    Rabie, A.B.M.2
  • 42
    • 25144447797 scopus 로고    scopus 로고
    • Histologic and ultrastructural study on statin graft in rabbit skulls
    • R.W. Wong, and A.B. Rabie Histologic and ultrastructural study on statin graft in rabbit skulls J Oral Maxillofac Surg 63 10 2005 1515 1521
    • (2005) J Oral Maxillofac Surg , vol.63 , Issue.10 , pp. 1515-1521
    • Wong, R.W.1    Rabie, A.B.2
  • 43
    • 38949088667 scopus 로고    scopus 로고
    • The effect of simvastatin on remodelling of the alveolar bone following tooth extraction
    • Z. Wu, C. Liu, G. Zang, and H. Sun The effect of simvastatin on remodelling of the alveolar bone following tooth extraction Int J Oral Maxillofac Surg 37 2008 170 176
    • (2008) Int J Oral Maxillofac Surg , vol.37 , pp. 170-176
    • Wu, Z.1    Liu, C.2    Zang, G.3    Sun, H.4
  • 44
    • 41149125432 scopus 로고    scopus 로고
    • Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2 induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway
    • M. Yamashita, F. Otsuka, T. Mukai, H. Otani, K. Inagaki, and T. Miyoshi Simvastatin antagonizes tumor necrosis factor-alpha inhibition of bone morphogenetic proteins-2 induced osteoblast differentiation by regulating Smad signaling and Ras/Rho-mitogen-activated protein kinase pathway J Endocrinol 196 2008 601 603
    • (2008) J Endocrinol , vol.196 , pp. 601-603
    • Yamashita, M.1    Otsuka, F.2    Mukai, T.3    Otani, H.4    Inagaki, K.5    Miyoshi, T.6


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