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Volumn 20, Issue 3, 2005, Pages 438-444

The effect of simvastatin on the proliferation and differentiation of human bone marrow stromal cells

Author keywords

Bone Marrow Cells; Cell Differentiation; Cell Proliferation; Osteoblasts; Simvastatin; Stromal Cells

Indexed keywords

ALKALINE PHOSPHATASE; OSTEOCALCIN; SIMVASTATIN; TETRAZOLIUM;

EID: 21344462154     PISSN: 10118934     EISSN: None     Source Type: Journal    
DOI: 10.3346/jkms.2005.20.3.438     Document Type: Article
Times cited : (93)

References (42)
  • 3
    • 0034709764 scopus 로고    scopus 로고
    • Oral statins and increased bone mineral density in postmenopausal women
    • Edwards CJ, Hart DJ, Spector TD. Oral statins and increased bone mineral density in postmenopausal women. Lancet 2000; 355: 2218-9.
    • (2000) Lancet , vol.355 , pp. 2218-2219
    • Edwards, C.J.1    Hart, D.J.2    Spector, T.D.3
  • 6
    • 0034725357 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors and the risk of hip fractures in elderly patients
    • Wang PS, Solomon DH, Mogun H, Avorn J. HMG-CoA reductase inhibitors and the risk of hip fractures in elderly patients. JAMA 2000; 283: 3211-6.
    • (2000) JAMA , vol.283 , pp. 3211-3216
    • Wang, P.S.1    Solomon, D.H.2    Mogun, H.3    Avorn, J.4
  • 8
    • 0034957690 scopus 로고    scopus 로고
    • The effect of fluvastatin on parameters of bone remodeling
    • Bjarnason NH, Riis BJ, Christiansen C. The effect of fluvastatin on parameters of bone remodeling. Osteoporos Int 2001; 12: 380-4.
    • (2001) Osteoporos Int , vol.12 , pp. 380-384
    • Bjarnason, N.H.1    Riis, B.J.2    Christiansen, C.3
  • 9
    • 0036063969 scopus 로고    scopus 로고
    • Relation of statin use and bone loss: A prospective population-based cohort study in early postmenopausal women
    • Sirola J, Honkanen R, Kröger H, Jurvelin JS, Mäenpää P, Saarikoski S. Relation of statin use and bone loss: A prospective population-based cohort study in early postmenopausal women. Osteoporos Int 2002; 13: 537-41.
    • (2002) Osteoporos Int , vol.13 , pp. 537-541
    • Sirola, J.1    Honkanen, R.2    Kröger, H.3    Jurvelin, J.S.4    Mäenpää, P.5    Saarikoski, S.6
  • 11
    • 0035211808 scopus 로고    scopus 로고
    • Statin given perorally to adult rats increases cancellous bone mass and compressive strength
    • Oxlund H, Dalstra M, Andreassen T. Statin given perorally to adult rats increases cancellous bone mass and compressive strength. Calcif Tissue Int 2001; 69: 299-304.
    • (2001) Calcif Tissue Int , vol.69 , pp. 299-304
    • Oxlund, H.1    Dalstra, M.2    Andreassen, T.3
  • 14
    • 0034805319 scopus 로고    scopus 로고
    • Simvastatin promotes osteoblast differentiation and mineralization in MC3T3-E1 cells
    • Maeda T, Matsunuma A, Kawane T, Horiuchi N. Simvastatin promotes osteoblast differentiation and mineralization in MC3T3-E1 cells. Biochem Biophys Res Commun 2001; 280: 874-7.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 874-877
    • Maeda, T.1    Matsunuma, A.2    Kawane, T.3    Horiuchi, N.4
  • 15
    • 0034685669 scopus 로고    scopus 로고
    • Compactin and simvastatin, but not pravastatin induce bone morphogenetic protein-2 in human osteosarcoma cells
    • Sugiyama M, Kodama T, Konishi K, Abe K, Asami S, Oikawa S. Compactin and simvastatin, but not pravastatin induce bone morphogenetic protein-2 in human osteosarcoma cells. Biochem Biophys Res Commun 2000; 271: 688-92.
    • (2000) Biochem Biophys Res Commun , vol.271 , pp. 688-692
    • Sugiyama, M.1    Kodama, T.2    Konishi, K.3    Abe, K.4    Asami, S.5    Oikawa, S.6
  • 17
    • 0031792583 scopus 로고    scopus 로고
    • Thyroid hormone excess increases insulin-like growth factor I transcripts in bone marrow cell cultures: Divergent effects on vertebral and femoral cell cultures
    • Milne M, Kang MI, Quail JM, Baran DT. Thyroid hormone excess increases insulin-like growth factor I transcripts in bone marrow cell cultures: divergent effects on vertebral and femoral cell cultures. Endocrinology 1998; 139: 2527-34.
    • (1998) Endocrinology , vol.139 , pp. 2527-2534
    • Milne, M.1    Kang, M.I.2    Quail, J.M.3    Baran, D.T.4
  • 19
    • 0021858486 scopus 로고
    • Bone cell phosphotyrosine phosphatase: Characterization and regulation by calcitropic hormones
    • Puzas JE, Brand JS. Bone cell phosphotyrosine phosphatase: Characterization and regulation by calcitropic hormones. Endocrinology 1985; 116: 2463-8.
    • (1985) Endocrinology , vol.116 , pp. 2463-2468
    • Puzas, J.E.1    Brand, J.S.2
  • 20
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mossmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mossmann, T.1
  • 22
    • 0035212177 scopus 로고    scopus 로고
    • Statins and their potential for osteoporosis
    • Mundy GR. Statins and their potential for osteoporosis. Bone 2001; 29: 495-7.
    • (2001) Bone , vol.29 , pp. 495-497
    • Mundy, G.R.1
  • 23
    • 7044237064 scopus 로고    scopus 로고
    • Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atrovastatin when coadministered with cytochrome P450 inhibitors
    • Jacobson TA. Comparative pharmacokinetic interaction profiles of pravastatin, simvastatin, and atrovastatin when coadministered with cytochrome P450 inhibitors. Am J Cardiol 2004; 94: 1140-6.
    • (2004) Am J Cardiol , vol.94 , pp. 1140-1146
    • Jacobson, T.A.1
  • 24
    • 84990622726 scopus 로고
    • Bone marrow osteogenic stem cells: In vitro cultivation and transplantation in diffusion chambers
    • Friedenstein AJ, Chailakhyan RK, Gerasimov UV. Bone marrow osteogenic stem cells: in vitro cultivation and transplantation in diffusion chambers. Cell Tissue Kinet 1987; 20: 263-72.
    • (1987) Cell Tissue Kinet , vol.20 , pp. 263-272
    • Friedenstein, A.J.1    Chailakhyan, R.K.2    Gerasimov, U.V.3
  • 25
    • 84989485234 scopus 로고
    • The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells
    • Friedenstein AJ, Chailakhyan RK, Lalykina KS. The development of fibroblast colonies in monolayer cultures of guinea-pig bone marrow and spleen cells. Cell Tissue Kinet 1970; 3: 393-403.
    • (1970) Cell Tissue Kinet , vol.3 , pp. 393-403
    • Friedenstein, A.J.1    Chailakhyan, R.K.2    Lalykina, K.S.3
  • 26
    • 0030831553 scopus 로고    scopus 로고
    • Short-term treatment of rats with high-dose 1,25-dihydroxyvitamin D3 stimulates bone formation and increases the number of osteoblast precursor cells in bone marrow
    • Erben RG, Scutt AM, Miao D, Kollenkirchen U, Haberey M. Short-term treatment of rats with high-dose 1,25-dihydroxyvitamin D3 stimulates bone formation and increases the number of osteoblast precursor cells in bone marrow. Endocrinology 1997; 138: 4629-35.
    • (1997) Endocrinology , vol.138 , pp. 4629-4635
    • Erben, R.G.1    Scutt, A.M.2    Miao, D.3    Kollenkirchen, U.4    Haberey, M.5
  • 27
    • 0031000236 scopus 로고    scopus 로고
    • Systemic administration of an anabolic dose of PGE2 in young rats increases the osteogenic capacity of bone marrow
    • Weinreb M, Suponitzky I, Keila S. Systemic administration of an anabolic dose of PGE2 in young rats increases the osteogenic capacity of bone marrow. Bone 1997; 20: 521-6.
    • (1997) Bone , vol.20 , pp. 521-526
    • Weinreb, M.1    Suponitzky, I.2    Keila, S.3
  • 28
    • 0030698388 scopus 로고    scopus 로고
    • Regulation of bone matrix protein expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein-2
    • Lecanda F, Avioli LV, Cheng SL. Regulation of bone matrix protein expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein-2. J Biol Chem 1997; 265: 386-96.
    • (1997) J Biol Chem , vol.265 , pp. 386-396
    • Lecanda, F.1    Avioli, L.V.2    Cheng, S.L.3
  • 29
    • 0031044104 scopus 로고    scopus 로고
    • Recombinant human bone morphogenetic protein-2 stimulates differentiation in primary cultures of fetal rat calvarial osteoblasts
    • Chaudhari A, Ron E, Rethman MP. Recombinant human bone morphogenetic protein-2 stimulates differentiation in primary cultures of fetal rat calvarial osteoblasts. Mol Cell Biochem 1997; 167: 31-9.
    • (1997) Mol Cell Biochem , vol.167 , pp. 31-39
    • Chaudhari, A.1    Ron, E.2    Rethman, M.P.3
  • 30
    • 0032521349 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 and transforming growth factor-beta2 interact to modulate human bone marrow stromal cell proliferation and differentiation
    • Fromigue O, Marie PJ, Lomri A. Bone morphogenetic protein-2 and transforming growth factor-beta2 interact to modulate human bone marrow stromal cell proliferation and differentiation. J Cell Biochem 1998; 68: 411-26.
    • (1998) J Cell Biochem , vol.68 , pp. 411-426
    • Fromigue, O.1    Marie, P.J.2    Lomri, A.3
  • 31
    • 0028969468 scopus 로고
    • Comparisons of in vivo and in vitro models of the response of osteoblasts to hormonal regulation with aging
    • Hock JM, Onyia J, Bidwell J. Comparisons of in vivo and in vitro models of the response of osteoblasts to hormonal regulation with aging. Calcif Tissue Int 1995; 56 (Suppl 1): S44-7.
    • (1995) Calcif Tissue Int , vol.56 , Issue.1 SUPPL.
    • Hock, J.M.1    Onyia, J.2    Bidwell, J.3
  • 32
    • 0028148489 scopus 로고
    • Increased bone formation by intermittent parathyroid hormone administration is due to the stimulation of proliferation and differentiation of osteoprogenitor cells in the bone marrow
    • Nishida S, Yamaguchi A, Tanizawa T, Endo N, Mashiba T, Uchiyama Y, Suda T, Yoshiki S, Takahashi HE. Increased bone formation by intermittent parathyroid hormone administration is due to the stimulation of proliferation and differentiation of osteoprogenitor cells in the bone marrow. Bone 1994; 15: 717-23.
    • (1994) Bone , vol.15 , pp. 717-723
    • Nishida, S.1    Yamaguchi, A.2    Tanizawa, T.3    Endo, N.4    Mashiba, T.5    Uchiyama, Y.6    Suda, T.7    Yoshiki, S.8    Takahashi, H.E.9
  • 33
    • 0036828498 scopus 로고    scopus 로고
    • Mechanisms for the enhancement of fracture healing in rats treated with intermittent low-dose human parathyroid hormone (1-34)
    • Nakajima A, Shimoji N, Shiomi K, Shimizu S, Moriya H, Einhorn TA, Yamazaki M. Mechanisms for the enhancement of fracture healing in rats treated with intermittent low-dose human parathyroid hormone (1-34). J Bone Miner Res 2002; 17: 2038-47.
    • (2002) J Bone Miner Res , vol.17 , pp. 2038-2047
    • Nakajima, A.1    Shimoji, N.2    Shiomi, K.3    Shimizu, S.4    Moriya, H.5    Einhorn, T.A.6    Yamazaki, M.7
  • 34
    • 0027295137 scopus 로고
    • Insulin like growth factors and the local regulation of bone formation
    • Canalis E. Insulin like growth factors and the local regulation of bone formation. Bone 1993; 14: 273-6.
    • (1993) Bone , vol.14 , pp. 273-276
    • Canalis, E.1
  • 35
    • 0021229954 scopus 로고
    • Insulin-like growth factor I supports differentiation of cultured osteoblast-like cells
    • Schmid C, Steiner T, Froesch ER. Insulin-like growth factor I supports differentiation of cultured osteoblast-like cells. FEBS Lett 1984; 173: 48-52.
    • (1984) FEBS Lett , vol.173 , pp. 48-52
    • Schmid, C.1    Steiner, T.2    Froesch, E.R.3
  • 38
    • 0035901052 scopus 로고    scopus 로고
    • Effect of pravastatin on frequency of fracture in the LIPID study: Secondary analysis of a randomised controlled trial
    • Reid IR, Hague W, Emberson J, Baker J, Tonkin A, Hunt D, MacMahon S, Sharpe N. Effect of pravastatin on frequency of fracture in the LIPID study: secondary analysis of a randomised controlled trial. Lancet 2001; 357: 509-12.
    • (2001) Lancet , vol.357 , pp. 509-512
    • Reid, I.R.1    Hague, W.2    Emberson, J.3    Baker, J.4    Tonkin, A.5    Hunt, D.6    MacMahon, S.7    Sharpe, N.8
  • 39
    • 0034970424 scopus 로고    scopus 로고
    • Pravastatin therapy increases procollagen I N-terminal propeptide (PINP), a marker of bone formation in post-menopausal women
    • Mostaza JM, De la Piedra C, Curiel MD, Pena R, Lahoz C. Pravastatin therapy increases procollagen I N-terminal propeptide (PINP), a marker of bone formation in post-menopausal women. Clin Chim Acta 2001; 308: 133-7.
    • (2001) Clin Chim Acta , vol.308 , pp. 133-137
    • Mostaza, J.M.1    De La Piedra, C.2    Curiel, M.D.3    Pena, R.4    Lahoz, C.5
  • 40
    • 0034848003 scopus 로고    scopus 로고
    • Simvastatin increases serum osteocalcin concentration in patients treated for hypercholesterolaemia
    • Chan MH, Mak TW, Chiu RW, Chow CC, Chan IH, Lam CW. Simvastatin increases serum osteocalcin concentration in patients treated for hypercholesterolaemia. J Clin Endocrinol Metab 2001; 86: 4556-9.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4556-4559
    • Chan, M.H.1    Mak, T.W.2    Chiu, R.W.3    Chow, C.C.4    Chan, I.H.5    Lam, C.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.