메뉴 건너뛰기




Volumn 19, Issue 6, 2008, Pages 558-562

Safety of statins

Author keywords

Liver dysfunction; Proteinuria and neuropathy; Rhabdomyolysis; Statin

Indexed keywords

AMIODARONE; ANTIFUNGAL AGENT; ATORVASTATIN; CALCIUM CHANNEL BLOCKING AGENT; CERIVASTATIN; CYCLOSPORIN; EZETIMIBE; FENOFIBRATE; FLUINDOSTATIN; GEMFIBROZIL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN; MACROLIDE; MEVALONIC ACID; MEVINOLIN; PHENYTOIN; PLACEBO; PRAVASTATIN; ROSUVASTATIN; SIMVASTATIN; UBIQUINONE; WARFARIN;

EID: 56549100353     PISSN: 09579672     EISSN: None     Source Type: Journal    
DOI: 10.1097/MOL.0b013e328319baba     Document Type: Review
Times cited : (55)

References (38)
  • 1
    • 33751507008 scopus 로고    scopus 로고
    • Primary prevention of cardiovascular diseases with statin therapy: A meta-analysis of randomized controlled trials
    • Thavendiranathan P, Bagai A, Brookhart MA, Choudhry NK. Primary prevention of cardiovascular diseases with statin therapy: a meta-analysis of randomized controlled trials. Arch Internal Med 2006; 166:2307-2313.
    • (2006) Arch Internal Med , vol.166 , pp. 2307-2313
    • Thavendiranathan, P.1    Bagai, A.2    Brookhart, M.A.3    Choudhry, N.K.4
  • 2
    • 34248196018 scopus 로고    scopus 로고
    • Incremental benefit and cost-effectiveness of high-dose statin therapy in high-risk patients with coronary artery disease
    • Chan PS, Nallamothu BK, Gurm HS, et al. Incremental benefit and cost-effectiveness of high-dose statin therapy in high-risk patients with coronary artery disease. Circulation 2007; 115:2398-2409.
    • (2007) Circulation , vol.115 , pp. 2398-2409
    • Chan, P.S.1    Nallamothu, B.K.2    Gurm, H.S.3
  • 3
    • 0031994862 scopus 로고    scopus 로고
    • Sterol regulatory element binding proteins (SREBPs): Controllers of lipid synthesis and cellular uptake
    • Brown M, Goldstein J. Sterol regulatory element binding proteins (SREBPs): controllers of lipid synthesis and cellular uptake. Nutr Rev 1998; 56:S1-S6.
    • (1998) Nutr Rev , vol.56
    • Brown, M.1    Goldstein, J.2
  • 5
    • 35348863203 scopus 로고    scopus 로고
    • Effect of coenzyme Q(10) supplementation on simvastatin-induced myalgia
    • Young JM, Florkowski CM, Molyneux SL, et al. Effect of coenzyme Q(10) supplementation on simvastatin-induced myalgia. Am J Cardiol 2007; 100:1400-1403.
    • (2007) Am J Cardiol , vol.100 , pp. 1400-1403
    • Young, J.M.1    Florkowski, C.M.2    Molyneux, S.L.3
  • 6
    • 33746848052 scopus 로고    scopus 로고
    • Effect of eztimibe and/or simvastatin on coenzyme Q10 levels in plasma: A randomized trial
    • Berthold HK, Naini A, Di Mauro S, et al. Effect of eztimibe and/or simvastatin on coenzyme Q10 levels in plasma: a randomized trial. Drug Saf 2006; 29:703-712.
    • (2006) Drug Saf , vol.29 , pp. 703-712
    • Berthold, H.K.1    Naini, A.2    Di Mauro, S.3
  • 7
    • 48549092122 scopus 로고    scopus 로고
    • Plasma coenzyme Q10 predicts lipid-lowering response to high-dose atorvastatin
    • Pacanowski MA, Frye RF, Osatohanmen E, et al. Plasma coenzyme Q10 predicts lipid-lowering response to high-dose atorvastatin. J Clin Lipid 2008; 2:289-297.
    • (2008) J Clin Lipid , vol.2 , pp. 289-297
    • Pacanowski, M.A.1    Frye, R.F.2    Osatohanmen, E.3
  • 8
    • 0037490080 scopus 로고    scopus 로고
    • Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke systematic review and meta-analysis
    • Law MR, Wald NJ, Rudnicka AR. Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke systematic review and meta-analysis. BMJ 2003; 326:1423-1430.
    • (2003) BMJ , vol.326 , pp. 1423-1430
    • Law, M.R.1    Wald, N.J.2    Rudnicka, A.R.3
  • 9
    • 0036894223 scopus 로고    scopus 로고
    • Etiology and frequency of rhabdomyolysis
    • Black C, Jick H. Etiology and frequency of rhabdomyolysis. Pharmacotherapy 2002; 22:1524-1526.
    • (2002) Pharmacotherapy , vol.22 , pp. 1524-1526
    • Black, C.1    Jick, H.2
  • 10
    • 9644252909 scopus 로고    scopus 로고
    • Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs
    • Graham DJ, Staffa JA, Shatin D, et al. Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs. JAMA 2004; 292:2585-2590.
    • (2004) JAMA , vol.292 , pp. 2585-2590
    • Graham, D.J.1    Staffa, J.A.2    Shatin, D.3
  • 11
    • 33645881669 scopus 로고    scopus 로고
    • Statin safety: A systematic review
    • Law M, Rudnicka AR. Statin safety: a systematic review. Am J Cardiol 2006; 97 (Suppl 8A):52C-60C.
    • (2006) Am J Cardiol , vol.97 , Issue.SUPPL. 8A
    • Law, M.1    Rudnicka, A.R.2
  • 12
    • 27744603499 scopus 로고    scopus 로고
    • High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction: The IDEAL study: a randomized controlled trial
    • Pedersen TR, Faergeman O, Kastelein JJP, et al. High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction: the IDEAL study: a randomized controlled trial. JAMA 2005; 294:2437-2445.
    • (2005) JAMA , vol.294 , pp. 2437-2445
    • Pedersen, T.R.1    Faergeman, O.2    Kastelein, J.J.P.3
  • 13
    • 35448982396 scopus 로고    scopus 로고
    • Study of the effectiveness of additional reductions in cholesterol and homocysteine (SEARCH): Characteristics of a randomized trial among 12064 myocardial infarction survivors
    • SEARCH Study Collaborative Group
    • SEARCH Study Collaborative Group. Study of the effectiveness of additional reductions in cholesterol and homocysteine (SEARCH): characteristics of a randomized trial among 12064 myocardial infarction survivors. Am Heart J 2007; 154:815-823.
    • (2007) Am Heart J , vol.154 , pp. 815-823
  • 14
    • 0030777325 scopus 로고    scopus 로고
    • Lovastatin increases exercise-induced skeletal muscle injury
    • Thompson PD, Zmuda JM, Domalik LJ, et al. Lovastatin increases exercise-induced skeletal muscle injury. Metabolism 1997; 46:1206-1210.
    • (1997) Metabolism , vol.46 , pp. 1206-1210
    • Thompson, P.D.1    Zmuda, J.M.2    Domalik, L.J.3
  • 16
    • 0035657076 scopus 로고    scopus 로고
    • Association of polymorphism in the cytochrome CYP2D6 and the efficacy and tolerability of simvastatin
    • Mulder AB, van Liif HJ, Bon MA, et al. Association of polymorphism in the cytochrome CYP2D6 and the efficacy and tolerability of simvastatin. Clin Pharmacol Ther 2001; 70:546-551.
    • (2001) Clin Pharmacol Ther , vol.70 , pp. 546-551
    • Mulder, A.B.1    van Liif, H.J.2    Bon, M.A.3
  • 17
    • 28144440151 scopus 로고    scopus 로고
    • The role of common variants of ABCA1, CYP3A4, and CYP3A5 genes in lipid-lowering efficacy and tolerability of simvastatin
    • Fiegenbaum M, da Silveira FR, Van der Sand CR, et al. The role of common variants of ABCA1, CYP3A4, and CYP3A5 genes in lipid-lowering efficacy and tolerability of simvastatin. Clin Pharmacol Ther 2005; 78:551-558.
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 551-558
    • Fiegenbaum, M.1    da Silveira, F.R.2    Van der Sand, C.R.3
  • 19
    • 33645853175 scopus 로고    scopus 로고
    • Statin safety an overview and assessment of the data: 2005
    • Bays H. Statin safety an overview and assessment of the data: 2005. Am J Cardiol 2006; 97 (Suppl 8A):6C-26C.
    • (2006) Am J Cardiol , vol.97 , Issue.SUPPL. 8A
    • Bays, H.1
  • 20
    • 33645868967 scopus 로고    scopus 로고
    • Statin safety and drug interactions: Clinical implications
    • Bottorf MB. Statin safety and drug interactions: clinical implications. Am J Cardiol 2006; 97 (Suppl 8A):6C-26C.
    • (2006) Am J Cardiol , vol.97 , Issue.SUPPL. 8A
    • Bottorf, M.B.1
  • 21
    • 0036266987 scopus 로고    scopus 로고
    • Mechanistic studies on metabolic interactions between gemfibrozil and statins
    • Prueksaritanont T, Zhao JJ, Ma B, et al. Mechanistic studies on metabolic interactions between gemfibrozil and statins. J Pharmacol Exp Ther 2002; 301:1042-1051.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 1042-1051
    • Prueksaritanont, T.1    Zhao, J.J.2    Ma, B.3
  • 23
    • 1542345696 scopus 로고    scopus 로고
    • Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20,536 people with cerebrovascular disease or other high-risk conditions
    • Heart Protection Study Collaborative Group
    • Heart Protection Study Collaborative Group, Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20,536 people with cerebrovascular disease or other high-risk conditions. Lancet 2004; 363:757-767.
    • (2004) Lancet , vol.363 , pp. 757-767
  • 24
    • 0037031061 scopus 로고    scopus 로고
    • Heart Protection Study Collaborative Group, MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals a randomised placebo-controlled trial. Lancet 2002; 360:7-22.
    • Heart Protection Study Collaborative Group, MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals a randomised placebo-controlled trial. Lancet 2002; 360:7-22.
  • 25
    • 33645888317 scopus 로고    scopus 로고
    • An assessment of statin safety by hepatologists
    • Cohen DE, Anania FA, Chalasani N. An assessment of statin safety by hepatologists. Am J Cardiol 2006; 97 (Suppl 8A):77C-81C.
    • (2006) Am J Cardiol , vol.97 , Issue.SUPPL. 8A
    • Cohen, D.E.1    Anania, F.A.2    Chalasani, N.3
  • 26
    • 0035721965 scopus 로고    scopus 로고
    • Lipid lowering medication and hepatotoxicity
    • Kinnman N, Hultcrantz R. Lipid lowering medication and hepatotoxicity. J Intern Med 2001; 250:183-185.
    • (2001) J Intern Med , vol.250 , pp. 183-185
    • Kinnman, N.1    Hultcrantz, R.2
  • 27
    • 0037097465 scopus 로고    scopus 로고
    • The liver and lovastatin
    • Tolman KG. The liver and lovastatin. Am J Cardiol 2002; 89:1374-1380.
    • (2002) Am J Cardiol , vol.89 , pp. 1374-1380
    • Tolman, K.G.1
  • 28
    • 33645870418 scopus 로고    scopus 로고
    • Statin safety lessons from new drug applications for marketed statins
    • Jacobson TA. Statin safety lessons from new drug applications for marketed statins. Am J Cardiol 2006; 97 (Suppl 8A):44C-51C.
    • (2006) Am J Cardiol , vol.97 , Issue.SUPPL. 8A
    • Jacobson, T.A.1
  • 29
    • 4344566156 scopus 로고    scopus 로고
    • Inhibitors of HMG-CoA reductase reduce receptor-mediated endocytosis in human kidney proximal tubular cells
    • Verhulst A, D'Haese PC, De Broe ME. Inhibitors of HMG-CoA reductase reduce receptor-mediated endocytosis in human kidney proximal tubular cells. J Am Soc Nephrol 2004; 15:2249-2257.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2249-2257
    • Verhulst, A.1    D'Haese, P.C.2    De Broe, M.E.3
  • 30
    • 4344667844 scopus 로고    scopus 로고
    • Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase reduce receptor-mediated endocytosis in opossum kidney cells
    • Sidaway E, Davidson RG, McTaggart F, et al. Inhibitors of 3-hydroxy-3-methylglutaryl-CoA reductase reduce receptor-mediated endocytosis in opossum kidney cells. J Am Soc Nephrol 2004; 15:2258-2265.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2258-2265
    • Sidaway, E.1    Davidson, R.G.2    McTaggart, F.3
  • 31
    • 34548513542 scopus 로고    scopus 로고
    • Comparison of short-term renal effects and efficacy of rosuvastatin 40 mg and simvastatin 80 mg, followed by assessment of long-term renal effects of rosuvastatin 40 mg, in patients with dyslipidemia
    • Stein EA, Marais DA, Ducobu J, et al. Comparison of short-term renal effects and efficacy of rosuvastatin 40 mg and simvastatin 80 mg, followed by assessment of long-term renal effects of rosuvastatin 40 mg, in patients with dyslipidemia. J Clin Lipidol 2007; 1:287-299.
    • (2007) J Clin Lipidol , vol.1 , pp. 287-299
    • Stein, E.A.1    Marais, D.A.2    Ducobu, J.3
  • 32
    • 0037373832 scopus 로고    scopus 로고
    • controlled, prospective study of the effects of atorvastatin on proteinuria and progression of kidney disease
    • Bianchi R, Bigazzi A, Caiazza VM, Campese A. controlled, prospective study of the effects of atorvastatin on proteinuria and progression of kidney disease. Am J Kidney Dis 2003; 41:565-570.
    • (2003) Am J Kidney Dis , vol.41 , pp. 565-570
    • Bianchi, R.1    Bigazzi, A.2    Caiazza, V.M.3    Campese, A.4
  • 33
    • 0035166933 scopus 로고    scopus 로고
    • Lipids Renal Disease Progression Meta-Analysis Study Group. Effect of lipid reduction on the progression of renal disease a meta-analysis
    • Fried LF, Orchard TJ, Kasiske BL, Lipids Renal Disease Progression Meta-Analysis Study Group. Effect of lipid reduction on the progression of renal disease a meta-analysis. Kidney Int 2001; 59:260-269.
    • (2001) Kidney Int , vol.59 , pp. 260-269
    • Fried, L.F.1    Orchard, T.J.2    Kasiske, B.L.3
  • 34
    • 4644278069 scopus 로고    scopus 로고
    • Effect of fluvastatin on renal end points in the Assessment of Lescol in Renal Transplant (ALERT) trial
    • and other Assessment of Lescol in Renal Transplantation Study Investigators
    • Fellstrom B, Holdaas H, Jardine AG, et al., and other Assessment of Lescol in Renal Transplantation Study Investigators. Effect of fluvastatin on renal end points in the Assessment of Lescol in Renal Transplant (ALERT) trial. Kidney Int 2004; 66:1549-1555.
    • (2004) Kidney Int , vol.66 , pp. 1549-1555
    • Fellstrom, B.1    Holdaas, H.2    Jardine, A.G.3
  • 35
    • 33645847539 scopus 로고    scopus 로고
    • An assessment of statin safety by neurologists
    • Brass LM, Alberts MJ, Sparks L. An assessment of statin safety by neurologists. Am J Cardiol 2006; 97 (Suppl 8A):86C-88C.
    • (2006) Am J Cardiol , vol.97 , Issue.SUPPL. 8A
    • Brass, L.M.1    Alberts, M.J.2    Sparks, L.3
  • 36
  • 37
    • 0037164314 scopus 로고    scopus 로고
    • Pravastatin in elderly individuals at risk of vascular disease (PROSPER) a randomised controlled trial
    • PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) Study Group
    • PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) Study Group, Pravastatin in elderly individuals at risk of vascular disease (PROSPER) a randomised controlled trial. Lancet 2002; 360:1623-1630.
    • (2002) Lancet , vol.360 , pp. 1623-1630
  • 38
    • 33746895436 scopus 로고    scopus 로고
    • High-dose atorvastatin after stroke or transient ischemic attack
    • The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Investigators
    • The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Investigators. High-dose atorvastatin after stroke or transient ischemic attack. N Engl J Med 2006; 355:549-559.
    • (2006) N Engl J Med , vol.355 , pp. 549-559


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.