Local simvastatin effects on mandibular bone growth and inflammation

Journal of Periodontology

Volumn 76, Issue 11, 2005, Pages 1861-1870

  Stein, David ^a   Lee, Yeonju ^a   Schmid, Marian J ^a   Killpack, Byron ^a   Genrich, Mikala A ^a   Narayana, Nagamani ^a   Marx, David B ^b   Cullen, Diane M ^c   Reinhardt, Richard A ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^c CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Histology; Mandible; Mice; Osteogenic genes; Rats

Indexed keywords

COLLAGENASE 3; CYCLOOXYGENASE 2 INHIBITOR; FIBRONECTIN; INDOMETACIN; METHYLCELLULOSE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; POLYLACTIC ACID; PROCOLLAGEN; PROSTAGLANDIN SYNTHASE INHIBITOR; SIMVASTATIN;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ARTICLE; BONE GROWTH; CALVARIA; CONTROLLED STUDY; CORRELATION COEFFICIENT; DNA MICROARRAY; DOSE RESPONSE; DRUG MEGADOSE; FEMALE; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; IMPLANT; IN VIVO STUDY; INFLAMMATION; LOW DRUG DOSE; MANDIBLE; MORPHOMETRICS; MOUSE; NONHUMAN; OPTIMAL DRUG DOSE; RAT; RAT STRAIN; SINGLE DRUG DOSE; UPREGULATION;

ANIMALS; COLLAGENASES; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; FEMALE; FIBRONECTINS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INDOMETHACIN; INFLAMMATION MEDIATORS; LACTIC ACID; MANDIBLE; MATRIX METALLOPROTEINASE 13; MEMBRANES, ARTIFICIAL; METHYLCELLULOSE; MICE; NITROBENZENES; OSTEOGENESIS; POLYMERS; PROCOLLAGEN; RATS; SIMVASTATIN; SKULL; SULFONAMIDES; UP-REGULATION; VEHICLES;

EID: 28644438822     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2005.76.11.1861     Document Type: Article

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