Lineage-specific compaction of Tcrb requires a chromatin barrier to protect the function of a long-range tethering element

Journal of Experimental Medicine

Volumn 212, Issue 1, 2015, Pages 107-120

  Majumder, Kinjal ^a   Koues, Olivia I ^a   Chan, Elizabeth A W ^b   Kyle, Katherine E ^a   Horowitz, Julie E ^c   Yang Iott, Katherine ^c   Bassing, Craig H ^c   Taniuchi, Ichiro ^d   Krangel, Michael S ^b   Oltz, Eugene M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d RIKEN Center for Integrative Medical Sciences   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; RECOMBINASE; STRUCTURAL PROTEIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; TRANSCRIPTION FACTOR CTCF; CCCTC-BINDING FACTOR; CHROMATIN; HISTONE; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN BINDING; REPRESSOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMATIN; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DNA FLANKING REGION; ENHANCER REGION; GENE CLUSTER; GENE CONTROL; GENE FUNCTION; GENE INTERACTION; GENE LOCUS; GENETIC ASSOCIATION; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; THYMOCYTE; VDJ RECOMBINATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL LINEAGE; CYTOLOGY; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; METHYLATION; PRE B LYMPHOCYTE; PROCEDURES; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CELL LINEAGE; CELLS, CULTURED; CHROMATIN; ENHANCER ELEMENTS, GENETIC; GENE EXPRESSION REGULATION; HISTONES; IN SITU HYBRIDIZATION, FLUORESCENCE; METHYLATION; MICE, INBRED C57BL; MICE, KNOCKOUT; PRECURSOR CELLS, B-LYMPHOID; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THYMOCYTES; V(D)J RECOMBINATION; VDJ RECOMBINASES;

EID: 84921415561     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20141479     Document Type: Article

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