Vκ gene repertoire and locus contraction are specified by critical DNase I hypersensitive sites within the Vκ-Jκ intervening region

Journal of Immunology

Volumn 190, Issue 4, 2013, Pages 1819-1826

  Xiang, Yougui ^a,b   Park, Sung Kyun ^a   Garrard, William T ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; DEOXYRIBONUCLEASE I; IMMUNOGLOBULIN KAPPA CHAIN; TRANSCRIPTION FACTOR CTCF;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTRACTING ELEMENT FOR RECOMBINATION; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DNA SEQUENCE; DNA STRUCTURE; DNASE I HYPERSENSITIVE SITE; DNASE I HYPERSENSITIVE SITE 1; DNASE I HYPERSENSITIVE SITE 2; EPIGENETICS; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE DELETION; GENE EXPRESSION; GENE LOCUS; GENE REARRANGEMENT; GENE STRUCTURE; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN J KAPPA GENE; IMMUNOGLOBULIN KAPPA GENE; IMMUNOGLOBULIN V KAPPA GENE; MOUSE; NONHUMAN; PRE B LYMPHOCYTE; PRIORITY JOURNAL; TRANSCRIPTION INITIATION; VDJ RECOMBINATION; WILD TYPE;

ANIMALS; DEOXYRIBONUCLEASE I; DNA, INTERGENIC; GENE KNOCK-IN TECHNIQUES; GENE REARRANGEMENT, B-LYMPHOCYTE; HUMANS; IMMUNOGLOBULIN CONSTANT REGIONS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN JOINING REGION; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN VARIABLE REGION; INTEGRASES; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PRE-B CELL RECEPTORS; SEQUENCE DELETION;

EID: 84873557823     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1203127     Document Type: Article

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