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Volumn 35, Issue 1, 2015, Pages 406-418

AMP-Activated Protein Kinase 1 Regulates Cardiac Gap Junction Protein Connexin 43 and Electrical Remodeling Following Pressure Overload

Author keywords

Ampk1; Conduction; Cx43; Electrical remodeling; Ubiquitination

Indexed keywords

ADENOSINE 5' MONOPHOSPHATE ACTIVATED PROTEIN KINASE ALPHA 1; CONNEXIN 43; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; UNCLASSIFIED DRUG; AMPK ALPHA1 SUBUNIT, MOUSE;

EID: 84921387454     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000369706     Document Type: Article
Times cited : (36)

References (66)
  • 4
    • 0025780932 scopus 로고
    • Impact of left ventricular hypertrophy on ventricular arrhythmias in the absence of coronary artery disease
    • Ghali JK, Kadakia S, Cooper RS, Liao YL: Impact of left ventricular hypertrophy on ventricular arrhythmias in the absence of coronary artery disease. J Am Coll Cardiol 1991;17:1277-1282.
    • (1991) J Am Coll Cardiol , vol.17 , pp. 1277-1282
    • Ghali, J.K.1    Kadakia, S.2    Cooper, R.S.3    Liao, Y.L.4
  • 5
    • 84865846785 scopus 로고    scopus 로고
    • AMP-Activated protein kinase regulation and biological actions in the heart
    • Zaha VG, Young LH: AMP-Activated protein kinase regulation and biological actions in the heart. Circ Res 2012;111:800-814.
    • (2012) Circ Res , vol.111 , pp. 800-814
    • Zaha, V.G.1    Young, L.H.2
  • 6
    • 33847080728 scopus 로고    scopus 로고
    • AMP-Activated protein kinase in metabolic control and insulin signaling
    • Towler MC, Hardie DG: AMP-Activated protein kinase in metabolic control and insulin signaling. Circ Res 2007;100:328-341.
    • (2007) Circ Res , vol.100 , pp. 328-341
    • Towler, M.C.1    Hardie, D.G.2
  • 8
    • 0035797839 scopus 로고    scopus 로고
    • Increased adenosine monophosphate-Activated protein kinase activity in rat hearts with pressure-overload hypertrophy
    • Tian R, Musi N, D'Agostino J, Hirshman MF, Goodyear LJ: Increased adenosine monophosphate-Activated protein kinase activity in rat hearts with pressure-overload hypertrophy. Circulation 2001;104:1664-1669.
    • (2001) Circulation , vol.104 , pp. 1664-1669
    • Tian, R.1    Musi, N.2    D'Agostino, J.3    Hirshman, M.F.4    Goodyear, L.J.5
  • 11
    • 0037461107 scopus 로고    scopus 로고
    • Constitutively active adenosine monophosphate-Activated protein kinase regulates voltage-gated sodium channels in ventricular myocytes
    • Light PE, Wallace CH, Dyck JR: Constitutively active adenosine monophosphate-Activated protein kinase regulates voltage-gated sodium channels in ventricular myocytes. Circulation 2003;107:1962-1965.
    • (2003) Circulation , vol.107 , pp. 1962-1965
    • Light, P.E.1    Wallace, C.H.2    Dyck, J.R.3
  • 13
    • 67650032833 scopus 로고    scopus 로고
    • Alpha1-AMP-Activated protein kinase regulates hypoxia-induced Na,K-ATPase endocytosis via direct phosphorylation of protein kinase C zeta
    • Gusarova GA, Dada LA, Kelly AM, Brodie C, Witters LA, Chandel NS, Sznajder JI: Alpha1-AMP-Activated protein kinase regulates hypoxia-induced Na,K-ATPase endocytosis via direct phosphorylation of protein kinase C zeta. Mol Cell Biol 2009;29:3455-3464.
    • (2009) Mol Cell Biol , vol.29 , pp. 3455-3464
    • Gusarova, G.A.1    Dada, L.A.2    Kelly, A.M.3    Brodie, C.4    Witters, L.A.5    Chandel, N.S.6    Sznajder, J.I.7
  • 16
    • 84859811001 scopus 로고    scopus 로고
    • Effect of the AMP-kinase modulators AICAR, metformin and compound C on insulin secretion of INS-1E rat insulinoma cells under standard cell culture conditions
    • Langelueddecke C, Jakab M, Ketterl N, Lehner L, Hufnagl C, Schmidt S, Geibel JP, Fuerst J, Ritter M: Effect of the AMP-kinase modulators AICAR, metformin and compound C on insulin secretion of INS-1E rat insulinoma cells under standard cell culture conditions. Cell Physiol Biochem 2012;29:75-86.
    • (2012) Cell Physiol Biochem , vol.29 , pp. 75-86
    • Langelueddecke, C.1    Jakab, M.2    Ketterl, N.3    Lehner, L.4    Hufnagl, C.5    Schmidt, S.6    Geibel, J.P.7    Fuerst, J.8    Ritter, M.9
  • 18
    • 84885007602 scopus 로고    scopus 로고
    • MCT1 and MCT4 expression during myocardial ischemic-reperfusion injury in the isolated rat heart
    • Zhu Y, Wu J, Yuan SY: MCT1 and MCT4 expression during myocardial ischemic-reperfusion injury in the isolated rat heart. Cell Physiol Biochem 2013;32:663-674.
    • (2013) Cell Physiol Biochem , vol.32 , pp. 663-674
    • Zhu, Y.1    Wu, J.2    Yuan, S.Y.3
  • 20
    • 84897092493 scopus 로고    scopus 로고
    • Mutation in the gamma2-subunit of AMP-Activated protein kinase stimulates cardiomyocyte proliferation and hypertrophy independent of glycogen storage
    • Kim M, Hunter RW, Garcia-Menendez L, Gong G, Yang YY, Kolwicz SC, Jr., Xu J, Sakamoto K, Wang W, Tian R: Mutation in the gamma2-subunit of AMP-Activated protein kinase stimulates cardiomyocyte proliferation and hypertrophy independent of glycogen storage. Circ Res 2014;114:966-975.
    • (2014) Circ Res , vol.114 , pp. 966-975
    • Kim, M.1    Hunter, R.W.2    Garcia-Menendez, L.3    Gong, G.4    Yang, Y.Y.5    Kolwicz, S.C.6    Xu, J.7    Sakamoto, K.8    Wang, W.9    Tian, R.10
  • 21
    • 0345832116 scopus 로고    scopus 로고
    • Knockout of the alpha2 but not alpha1 5'-AMP-Activated protein kinase isoform abolishes 5-Aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle
    • Jorgensen SB, Viollet B, Andreelli F, Frosig C, Birk JB, Schjerling P, Vaulont S, Richter EA, Wojtaszewski JF: Knockout of the alpha2 but not alpha1 5'-AMP-Activated protein kinase isoform abolishes 5-Aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle. J Biol Chem 2004;279:1070-1079.
    • (2004) J Biol Chem , vol.279 , pp. 1070-1079
    • Jorgensen, S.B.1    Viollet, B.2    Andreelli, F.3    Frosig, C.4    Birk, J.B.5    Schjerling, P.6    Vaulont, S.7    Richter, E.A.8    Wojtaszewski, J.F.9
  • 27
    • 0025044073 scopus 로고
    • Quantification of spatial inhomogeneity in conduction and initiation of reentrant atrial arrhythmias
    • Lammers WJ, Schalij MJ, Kirchhof CJ, Allessie MA: Quantification of spatial inhomogeneity in conduction and initiation of reentrant atrial arrhythmias. Am J Physiol 1990;259:H1254-1263.
    • (1990) Am J Physiol , vol.259 , pp. H1254-1263
    • Lammers, W.J.1    Schalij, M.J.2    Kirchhof, C.J.3    Allessie, M.A.4
  • 37
    • 0017167448 scopus 로고
    • Inhibition of oocyte maturation by theophylline: Possible mechanism of action
    • O'Connor CM, Smith LD: Inhibition of oocyte maturation by theophylline: possible mechanism of action. Dev Biol 1976;52:318-322.
    • (1976) Dev Biol , vol.52 , pp. 318-322
    • O'Connor, C.M.1    Smith, L.D.2
  • 39
    • 62249106613 scopus 로고    scopus 로고
    • Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion
    • Ussher JR, Lopaschuk GD: Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion. Basic Res Cardiol 2009;104:203-210.
    • (2009) Basic Res Cardiol , vol.104 , pp. 203-210
    • Ussher, J.R.1    Lopaschuk, G.D.2
  • 41
    • 0028817813 scopus 로고
    • The gap junction protein connexin43 is degraded via the ubiquitin proteasome pathway
    • Laing JG, Beyer EC: The gap junction protein connexin43 is degraded via the ubiquitin proteasome pathway. J Biol Chem 1995;270:26399-26403.
    • (1995) J Biol Chem , vol.270 , pp. 26399-26403
    • Laing, J.G.1    Beyer, E.C.2
  • 42
    • 36348968263 scopus 로고    scopus 로고
    • Ubiquitination of gap junction proteins
    • Leithe E, Rivedal E: Ubiquitination of gap junction proteins. J Membr Biol 2007;217:43-51.
    • (2007) J Membr Biol , vol.217 , pp. 43-51
    • Leithe, E.1    Rivedal, E.2
  • 43
    • 9244265420 scopus 로고    scopus 로고
    • Ubiquitination and down-regulation of gap junction protein connexin-43 in response to 12-O-tetradecanoylphorbol 13-Acetate treatment
    • Leithe E, Rivedal E: Ubiquitination and down-regulation of gap junction protein connexin-43 in response to 12-O-tetradecanoylphorbol 13-Acetate treatment. J Biol Chem 2004;279:50089-50096.
    • (2004) J Biol Chem , vol.279 , pp. 50089-50096
    • Leithe, E.1    Rivedal, E.2
  • 45
    • 78649979349 scopus 로고    scopus 로고
    • AMP-Activated protein kinase inhibits KCNQ1 channels through regulation of the ubiquitin ligase Nedd4-2 in renal epithelial cells
    • Alzamora R, Gong F, Rondanino C, Lee JK, Smolak C, Pastor-Soler NM, Hallows KR: AMP-Activated protein kinase inhibits KCNQ1 channels through regulation of the ubiquitin ligase Nedd4-2 in renal epithelial cells. Am J Physiol Renal Physiol 2010;299:F1308-1319.
    • (2010) Am J Physiol Renal Physiol , vol.299 , pp. F1308-1319
    • Alzamora, R.1    Gong, F.2    Rondanino, C.3    Lee, J.K.4    Smolak, C.5    Pastor-Soler, N.M.6    Hallows, K.R.7
  • 46
    • 80255131441 scopus 로고    scopus 로고
    • AMP-Activated protein kinase regulates E3 ligases in rodent heart
    • Baskin KK, Taegtmeyer H: AMP-Activated protein kinase regulates E3 ligases in rodent heart. Circ Res 2011;109:1153-1161.
    • (2011) Circ Res , vol.109 , pp. 1153-1161
    • Baskin, K.K.1    Taegtmeyer, H.2
  • 47
    • 70349253984 scopus 로고    scopus 로고
    • AMP-Activated protein kinase enhances the expression of muscle-specific ubiquitin ligases despite its activation of IGF-1/Akt signaling in C2C12 myotubes
    • Tong JF, Yan X, Zhu MJ, Du M: AMP-Activated protein kinase enhances the expression of muscle-specific ubiquitin ligases despite its activation of IGF-1/Akt signaling in C2C12 myotubes. J Cell Biochem 2009;108:458-468.
    • (2009) J Cell Biochem , vol.108 , pp. 458-468
    • Tong, J.F.1    Yan, X.2    Zhu, M.J.3    Du, M.4
  • 49
    • 0032851539 scopus 로고    scopus 로고
    • Characterization of conduction in the ventricles of normal and heterozygous Cx43 knockout mice using optical mapping
    • Morley GE, Vaidya D, Samie FH, Lo C, Delmar M, Jalife J: Characterization of conduction in the ventricles of normal and heterozygous Cx43 knockout mice using optical mapping. J Cardiovasc Electrophysiol 1999;10:1361-1375.
    • (1999) J Cardiovasc Electrophysiol , vol.10 , pp. 1361-1375
    • Morley, G.E.1    Vaidya, D.2    Samie, F.H.3    Lo, C.4    Delmar, M.5    Jalife, J.6
  • 50
    • 1442359119 scopus 로고    scopus 로고
    • Slow conduction and enhanced anisotropy increase the propensity for ventricular tachyarrhythmias in adult mice with induced deletion of connexin43
    • Van Rijen HV, Eckardt D, Degen J, Theis M, Ott T, Willecke K, Jongsma HJ, Opthof T, de Bakker JM: Slow conduction and enhanced anisotropy increase the propensity for ventricular tachyarrhythmias in adult mice with induced deletion of connexin43. Circulation 2004;109:1048-1055.
    • (2004) Circulation , vol.109 , pp. 1048-1055
    • Van Rijen, H.V.1    Eckardt, D.2    Degen, J.3    Theis, M.4    Ott, T.5    Willecke, K.6    Jongsma, H.J.7    Opthof, T.8    De Bakker, J.M.9
  • 54
    • 39749165131 scopus 로고    scopus 로고
    • Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1
    • Bruce AF, Rothery S, Dupont E, Severs NJ: Gap junction remodelling in human heart failure is associated with increased interaction of connexin43 with ZO-1. Cardiovasc Res 2008;77:757-765.
    • (2008) Cardiovasc Res , vol.77 , pp. 757-765
    • Bruce, A.F.1    Rothery, S.2    Dupont, E.3    Severs, N.J.4
  • 55
    • 8444248188 scopus 로고    scopus 로고
    • Regulation of myocardial connexins during hypertrophic remodelling
    • Teunissen BE, Jongsma HJ, Bierhuizen MF: Regulation of myocardial connexins during hypertrophic remodelling. Eur Heart J 2004;25:1979-1989.
    • (2004) Eur Heart J , vol.25 , pp. 1979-1989
    • Teunissen, B.E.1    Jongsma, H.J.2    Bierhuizen, M.F.3
  • 56
    • 0036487237 scopus 로고    scopus 로고
    • Cardiac structure and function in young and senescent mice heterozygous for a connexin43 null mutation
    • Betsuyaku T, Kovacs A, Saffitz JE, Yamada KA: Cardiac structure and function in young and senescent mice heterozygous for a connexin43 null mutation. J Mol Cell Cardiol 2002;34:175-184.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 175-184
    • Betsuyaku, T.1    Kovacs, A.2    Saffitz, J.E.3    Yamada, K.A.4
  • 60
    • 84871215037 scopus 로고    scopus 로고
    • Cardiac-derived adiponectin induced by long-term insulin treatment ameliorates myocardial ischemia/reperfusion injury in type 1 diabetic mice via AMPK signaling
    • Pei H, Qu Y, Lu X, Yu Q, Lian K, Liu P, Yan W, Liu J, Ma Y, Liu Y, Li C, Li W, Lau WB, Zhang H, Tao L: Cardiac-derived adiponectin induced by long-term insulin treatment ameliorates myocardial ischemia/reperfusion injury in type 1 diabetic mice via AMPK signaling. Basic Res Cardiol 2013;108:322.
    • (2013) Basic Res Cardiol , vol.108 , pp. 322
    • Pei, H.1    Qu, Y.2    Lu, X.3    Yu, Q.4    Lian, K.5    Liu, P.6    Yan, W.7    Liu, J.8    Ma, Y.9    Liu, Y.10    Li, C.11    Li, W.12    Lau, W.B.13    Zhang, H.14    Tao, L.15
  • 65
    • 55949114398 scopus 로고    scopus 로고
    • AMP activated protein kinase-Alpha2 deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction in mice
    • Zhang P, Hu X, Xu X, Fassett J, Zhu G, Viollet B, Xu W, Wiczer B, Bernlohr DA, Bache RJ, Chen Y: AMP activated protein kinase-Alpha2 deficiency exacerbates pressure-overload-induced left ventricular hypertrophy and dysfunction in mice. Hypertension 2008;52:918-924.
    • (2008) Hypertension , vol.52 , pp. 918-924
    • Zhang, P.1    Hu, X.2    Xu, X.3    Fassett, J.4    Zhu, G.5    Viollet, B.6    Xu, W.7    Wiczer, B.8    Bernlohr, D.A.9    Bache, R.J.10    Chen, Y.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.