Up-regulation of K ir 2.1 (KCNJ2) by the serum & glucocorticoid inducible SGK3

Cellular Physiology and Biochemistry

Volumn 33, Issue 2, 2014, Pages 491-500

  Munoz, Carlos ^a,c   Pakladok, Tatsiana ^a   Almilaji, Ahmad ^a   Elvira, Bernat ^a   Decher, Niels ^b   Shumilina, Ekaterina ^a   Lang, Florian ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Cardiomyocytes; Cell membrane potential; Heart; KCNJ2; Neurons; SGK3

Indexed keywords

GLUCOCORTICOID; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; PROTEIN SERINE THREONINE KINASE; BREFELDIN A; PROTEIN; SGK3 PROTEIN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; INWARDLY RECTIFYING POTASSIUM CHANNEL; KCNJ2 PROTEIN, HUMAN; SGK3 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL MEMBRANE POTENTIAL; CONFOCAL MICROSCOPY; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; LOSS OF FUNCTION MUTATION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; UPREGULATION; VOLTAGE CLAMP TECHNIQUE; XENOPUS; CHEMOLUMINESCENCE; ELECTRIC CURRENT; FEMALE; HOMEOSTASIS; HUMAN; PROTEIN EXPRESSION; WILD TYPE; ANIMAL; BIOSYNTHESIS; DRUG EFFECT; GENETICS; METABOLISM; PHYSIOLOGY; XENOPUS LAEVIS;

ANIMALS; ANTI-BACTERIAL AGENTS; BREFELDIN A; CELL MEMBRANE; HUMANS; OOCYTES; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN-SERINE-THREONINE KINASES; UP-REGULATION; XENOPUS LAEVIS;

EID: 84895579400     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000358629     Document Type: Article

References (57)

1. Bhandaru M, Kempe DS, Rotte A, Capuano P, Pathare G, Sopjani M, Alesutan I, Tyan L, Huang DY, Siraskar B, Judenhofer MS, Stange G, Pichler BJ, Biber J, Quintanilla-Martinez L, Wagner CA, Pearce D, Foller M, Lang F: Decreased bone density and increased phosphaturia in gene-Targeted mice lacking functional serum-And glucocorticoid-inducible kinase 3. Kidney Int 2011;80:61-67.
2. Boehmer C, Palmada M, Rajamanickam J, Schniepp R, Amara S, Lang F: Post-Translational regulation of EAAT2 function by co-expressed ubiquitin ligase Nedd4-2 is impacted by SGK kinases. J Neurochem 2006;97:911-921.
3. Bohmer C, Sopjani M, Klaus F, Lindner R, Laufer J, Jeyaraj S, Lang F, Palmada M: The serum and glucocorticoid inducible kinases SGK1-3 stimulate the neutral amino acid transporter SLC6A19. Cell Physiol Biochem 2010;25:723-732.
4. Strutz-Seebohm N, Shojaiefard M, Christie D, Tavare J, Seebohm G, Lang F: PIKfyve in the SGK1 mediated regulation of the creatine transporter SLC6A8. Cell Physiol Biochem 2007;20:729-734.
5. Lang F, Bohmer C, Palmada M, Seebohm G, Strutz-Seebohm N, Vallon V: (Patho)physiological significance of the serum-And glucocorticoid-inducible kinase isoforms. Physiol Rev 2006;86:1151-1178.
6. Trepiccione F, Capasso G: SGK3: A novel regulator of renal phosphate transport? Kidney Int 2011;80:13-15.
7. Strutz-Seebohm N, Seebohm G, Korniychuk G, Baltaev R, Ureche O, Striegel M, Lang F: Additive regulation of GluR1 by stargazin and serum-And glucocorticoid-inducible kinase isoform SGK3. Pflugers Arch 2006;452:276-282.
8. Schmid E, Bhandaru M, Nurbaeva MK, Yang W, Szteyn K, Russo A, Leibrock C, Tyan L, Pearce D, Shumilina E, Lang F: SGK3 regulates Ca(2+) entry and migration of dendritic cells. Cell Physiol Biochem 2012;30:1423-1435.
9. Bohmer C, Palmada M, Kenngott C, Lindner R, Klaus F, Laufer J, Lang F: Regulation of the epithelial calcium channel TRPV6 by the serum and glucocorticoid-inducible kinase isoforms SGK1 and SGK3. FEBS Lett 2007;581:5586-5590.
10. Pasham V, Rotte A, Bhandaru M, Eichenmuller M, Frohlich H, Mack AF, Bobbala D, Yang W, Pearce D, Lang F: Regulation of gastric acid secretion by the serum and glucocorticoid inducible kinase isoform SGK3. J Gastroenterol 2011;46:305-317.
11. Maier G, Palmada M, Rajamanickam J, Shumilina E, Bohmer C, Lang F: Upregulation of HERG channels by the serum and glucocorticoid inducible kinase isoform SGK3. Cell Physiol Biochem 2006;18:177-186.
12. Lopatin AN, Nichols CG: Inward rectifiers in the heart: An update on I(K1). J Mol Cell Cardiol 2001;33:625-638.
13. Tristani-Firouzi M, Etheridge SP: Kir 2.1 channelopathies: The Andersen-Tawil syndrome. Pflugers Arch 2010;460:289-294.
14. Liu GX, Derst C, Schlichthorl G, Heinen S, Seebohm G, Bruggemann A, Kummer W, Veh RW, Daut J, Preisig-Muller R: Comparison of cloned Kir2 channels with native inward rectifier K+ channels from guinea-pig cardiomyocytes. J Physiol 2001;532:115-126.
15. Preisig-Muller R, Schlichthorl G, Goerge T, Heinen S, Bruggemann A, Rajan S, Derst C, Veh RW, Daut J: Heteromerization of Kir2.x potassium channels contributes to the phenotype of Andersen's syndrome. Proc Natl Acad Sci USA 2002;99:7774-7779.
16. Xia M, Jin Q, Bendahhou S, He Y, Larroque MM, Chen Y, Zhou Q, Yang Y, Liu Y, Liu B, Zhu Q, Zhou Y, Lin J, Liang B, Li L, Dong X, Pan Z, Wang R, Wan H, Qiu W, Xu W, Eurlings P, Barhanin J, Chen Y: A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation. Biochem Biophys Res Commun 2005;332:1012-1019.
17. Andersen ED, Krasilnikoff PA, Overvad H: Intermittent muscular weakness, extrasystoles, and multiple developmental anomalies. A new syndrome? Acta Paediatr Scand 1971;60:559-564.
18. Plaster NM, Tawil R, Tristani-Firouzi M, Canun S, Bendahhou S, Tsunoda A, Donaldson MR, Iannaccone ST, Brunt E, Barohn R, Clark J, Deymeer F, George AL, Jr., Fish FA, Hahn A, Nitu A, Ozdemir C, Serdaroglu P, Subramony SH, Wolfe G, Fu YH, Ptacek LJ: Mutations in Kir2.1 cause the developmental and episodic electrical phenotypes of Andersen's syndrome. Cell 2001;105:511-519.
19. Sansone V, Griggs RC, Meola G, Ptacek LJ, Barohn R, Iannaccone S, Bryan W, Baker N, Janas SJ, Scott W, Ririe D, Tawil R: Andersen's syndrome: A distinct periodic paralysis. Ann Neurol 1997;42:305-312.
20. Tawil R, Ptacek LJ, Pavlakis SG, DeVivo DC, Penn AS, Ozdemir C, Griggs RC: Andersen's syndrome: Potassium-sensitive periodic paralysis, ventricular ectopy, and dysmorphic features. Ann Neurol 1994;35:326-330.
21. Collins A, Larson M: Differential sensitivity of inward rectifier K+ channels to metabolic inhibitors. J Biol Chem 2002;277:35815-35818.
22. Lodge NJ, Normandin DE: Alterations in Ito1, IKr and Ik1 density in the BIO TO-2 strain of syrian myopathic hamsters. J Mol Cell Cardiol 1997;29:3211-3221.
23. Diaz RJ, Zobel C, Cho HC, Batthish M, Hinek A, Backx PH, Wilson GJ: Selective inhibition of inward rectifier K+ channels (Kir2.1 or Kir2.2) abolishes protection by ischemic preconditioning in rabbit ventricular cardiomyocytes. Circ Res 2004;95:325-332.
24. Liu Y, Liu D, Heath L, Meyers DM, Krafte DS, Wagoner PK, Silvia CP, Yu W, Curran ME: Direct activation of an inwardly rectifying potassium channel by arachidonic acid. Mol Pharmacol 2001;59:1061-1068.
25. Romanenko VG, Fang Y, Byfield F, Travis AJ, Vandenberg CA, Rothblat GH, Levitan I: Cholesterol sensitivity and lipid raft targeting of Kir2.1 channels. Biophys J 2004;87:3850-3861.
26. Donaldson MR, Jensen JL, Tristani-Firouzi M, Tawil R, Bendahhou S, Suarez WA, Cobo AM, Poza JJ, Behr E, Wagstaff J, Szepetowski P, Pereira S, Mozaffar T, Escolar DM, Fu YH, Ptacek LJ: PIP2 binding residues of Kir2.1 are common targets of mutations causing Andersen syndrome. Neurology 2003;60:1811-1816.
27. Rohacs T, Chen J, Prestwich GD, Logothetis DE: Distinct specificities of inwardly rectifying K(+) channels for phosphoinositides. J Biol Chem 1999;274:36065-36072.
28. Soom M, Schonherr R, Kubo Y, Kirsch C, Klinger R, Heinemann SH: Multiple PIP2 binding sites in Kir2.1 inwardly rectifying potassium channels. FEBS Lett 2001;490:49-53.
29. Xiao J, Zhen XG, Yang J: Localization of PIP2 activation gate in inward rectifier K+ channels. Nat Neurosci 2003;6:811-818.
30. Zitron E, Kiesecker C, Luck S, Kathofer S, Thomas D, Kreye VA, Kiehn J, Katus HA, Schoels W, Karle CA: Human cardiac inwardly rectifying current IKir2.2 is upregulated by activation of protein kinase A. Cardiovasc Res 2004;63:520-527.
31. Henry P, Pearson WL, Nichols CG: Protein kinase C inhibition of cloned inward rectifier (HRK1/KIR2.3) K+ channels expressed in Xenopus oocytes. J Physiol 1996;495:681-688.
32. Wischmeyer E, Doring F, Karschin A: Acute suppression of inwardly rectifying Kir2.1 channels by direct tyrosine kinase phosphorylation. J Biol Chem 1998;273:34063-34068.
33. Dart C, Leyland ML: Targeting of an A kinase-Anchoring protein, AKAP79, to an inwardly rectifying potassium channel, Kir2.1. J Biol Chem 2001;276:20499-20505.
34. Jones SV: Role of the small GTPase Rho in modulation of the inwardly rectifying potassium channel Kir2.1. Mol Pharmacol 2003;64:987-993.
35. Vicente R, Coma M, Busquets S, Moore-Carrasco R, Lopez-Soriano FJ, Argiles JM, Felipe A: The systemic inflammatory response is involved in the regulation of K+ channel expression in brain via TNF-Alpha-dependent and-independent pathways. FEBS Lett 2004;572:189-194.
36. Leyland ML, Dart C: An alternatively spliced isoform of PSD-93/chapsyn 110 binds to the inwardly rectifying potassium channel, Kir2.1. J Biol Chem 2004;279:43427-43436.
37. Sampson LJ, Leyland ML, Dart C: Direct interaction between the actin-binding protein filamin-A and the inwardly rectifying potassium channel, Kir2.1. J Biol Chem 2003;278:41988-41997.
38. Nehring RB, Wischmeyer E, Doring F, Veh RW, Sheng M, Karschin A: Neuronal inwardly rectifying K+ channels differentially couple to PDZ proteins of the PSD-95/SAP90 family. J Neurosci 2000;20:156-162.
39. Leonoudakis D, Conti LR, Radeke CM, McGuire LM, Vandenberg CA: A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels. J Biol Chem 2004;279:19051-19063.
40. Henrion U, Zumhagen S, Steinke K, Strutz-Seebohm N, Stallmeyer B, Lang F, Schulze-Bahr E, Seebohm G: Overlapping cardiac phenotype associated with a familial mutation in the voltage sensor of the KCNQ1 channel. Cell Physiol Biochem 2012;29:809-818.
41. Ureche ON, Baltaev R, Ureche L, Strutz-Seebohm N, Lang F, Seebohm G: Novel insights into the structural basis of pH-sensitivity in inward rectifier K+ channels Kir2.3. Cell Physiol Biochem 2008;21:347-356.
42. Limberg MM, Zumhagen S, Netter MF, Coffey AJ, Grace A, Rogers J, Bockelmann D, Rinne S, Stallmeyer B, Decher N, Schulze-Bahr E: Non dominant-negative KCNJ2 gene mutations leading to Andersen-Tawil syndrome with an isolated cardiac phenotype. Basic Res Cardiol 2013;108:353.
43. Kobayashi T, Deak M, Morrice N, Cohen P: Characterization of the structure and regulation of two novel isoforms of serum-And glucocorticoid- induced protein kinase. Biochem J 1999;344:189-197.
44. Klaus F, Palmada M, Lindner R, Laufer J, Jeyaraj S, Lang F, Boehmer C: Up-regulation of hypertonicity-Activated myo-inositol transporter SMIT1 by the cell volume-sensitive protein kinase SGK1. J Physiol 2008;586:1539-1547.
45. Bogatikov E, Munoz C, Pakladok T, Alesutan I, Shojaiefard M, Seebohm G, Foller M, Palmada M, Bohmer C, Broer S, Lang F: Up-regulation of amino acid transporter SLC6A19 activity and surface protein abundance by PKB/Akt and PIKfyve. Cell Physiol Biochem 2012;30:1538-1546.
46. Hosseinzadeh Z, Bhavsar SK, Lang F: Down-regulation of the myoinositol transporter SMIT by JAK2. Cell Physiol Biochem 2012;30:1473-1480.
47. Almilaji A, Munoz C, Hosseinzadeh Z, Lang F: Upregulation of Na+,Cl-coupled betaine/gamma-Amino-butyric acid transporter BGT1 by Tau tubulin kinase 2. Cell Physiol Biochem 2013;32:334-343.
48. Hosseinzadeh Z, Dong L, Bhavsar SK, Warsi J, Almilaji A, Lang F: Upregulation of peptide transporters PEPT1 and PEPT2 by Janus kinase JAK2. Cell Physiol Biochem 2013;31:673-682.
49. Kirkbride KC, Hong NH, French CL, Clark ES, Jerome WG, Weaver AM: Regulation of late endosomal/lysosomal maturation and trafficking by cortactin affects Golgi morphology. Cytoskeleton (Hoboken) 2012;69:625-643.
50. Klausner RD, Donaldson JG, Lippincott-Schwartz J: Brefeldin A: Insights into the control of membrane traffic and organelle structure. J Cell Biol 1992;116:1071-1080.
51. Alesutan I, Sopjani M, Dermaku-Sopjani M, Munoz C, Voelkl J, Lang F: Upregulation of Na-coupled glucose transporter SGLT1 by Tau tubulin kinase 2. Cell Physiol Biochem 2012;30:458-465.
52. Almilaji A, Szteyn K, Fein E, Pakladok T, Munoz C, Elvira B, Towhid ST, Alesutan I, Shumilina E, Bock CT, Kandolf R, Lang F: Down-regulation of Na/K+ atpase activity by human parvovirus B19 capsid protein VP1. Cell Physiol Biochem 2013;31:638-648.
53. Pakladok T, Almilaji A, Munoz C, Alesutan I, Lang F: PIKfyve sensitivity of hERG channels. Cell Physiol Biochem 2013;31:785-794.
54. Mia S, Munoz C, Pakladok T, Siraskar G, Voelkl J, Alesutan I, Lang F: Downregulation of Kv1.5 K channels by the AMP-Activated protein kinase. Cell Physiol Biochem 2012;30:1039-1050.
55. Hosseinzadeh Z, Bhavsar SK, Lang F: Downregulation of ClC-2 by JAK2. Cell Physiol Biochem 2012;29:737-742.
56. Ackermann TF, Boini KM, Beier N, Scholz W, Fuchss T, Lang F: EMD638683, a novel SGK inhibitor with antihypertensive potency. Cell Physiol Biochem 2011;28:137-146.
57. Seebohm G, Strutz-Seebohm N, Ursu ON, Preisig-Muller R, Zuzarte M, Hill EV, Kienitz MC, Bendahhou S, Fauler M, Tapken D, Decher N, Collins A, Jurkat-Rott K, Steinmeyer K, Lehmann-Horn F, Daut J, Tavare JM, Pott L, Bloch W, Lang F: Altered stress stimulation of inward rectifier potassium channels in Andersen-Tawil syndrome. FASEB J 2012;26:513-522.