NADPH oxidase 2-dependent oxidative stress, mitochondrial damage and apoptosis in the ventral cochlear nucleus of D-galactose-induced aging rats

Neuroscience

Volumn 286, Issue , 2015, Pages 281-292

  Du, Z ^a   Yang, Q ^a   Liu, L ^b   Li, S ^a   Zhao, J ^a   Hu, J ^a   Liu, C ^a   Qian, D ^a   Gao, C ^a  

^a GUANGDONG MEDICAL UNIVERSITY   (China)

^b GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

Age related hearing loss; Apoptosis; Central auditory system (CAS); Mitochondrial DNA common deletion (mtDNA CD); NADPH oxidase 2 (NOX2); Oxidative damage

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ADENOSINE TRIPHOSPHATE; CASPASE 3; GALACTOSE; HYDROGEN PEROXIDE; MESSENGER RNA; MITOCHONDRIAL DNA; PROTEIN P22; PROTEIN P47; PROTEIN P67; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; AUDITORY SYSTEM; COCHLEAR NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA ISOLATION; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE DELETION; IMMUNOHISTOCHEMISTRY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PRESBYACUSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; ANIMAL; GENETICS; METABOLISM; MITOCHONDRION; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

AGING; ANIMALS; APOPTOSIS; COCHLEAR NUCLEUS; DNA, MITOCHONDRIAL; GALACTOSE; MALE; MITOCHONDRIA; NADPH OXIDASE; OXIDATIVE STRESS; PRESBYCUSIS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 84921367697     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.11.061     Document Type: Article

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