The neem limonoids azadirachtin and nimbolide induce cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells

Free Radical Research

Volumn 44, Issue 6, 2010, Pages 624-634

  Priyadarsini, R Vidya ^a   Murugan, R Senthil ^a   Sripriya, P ^b   Karunagaran, D ^b   Nagini, S ^a  

^a ANNAMALAI UNIVERSITY   (India)

^b INDIAN INSTITUTE OF TECHNOLOGY MADRAS   (India)

Author keywords

Antioxidant; Apoptosis; Azadirachtin; Cell cycle; Neem; Nimbolide

Indexed keywords

AZADIRACHTIN; CASPASE; CYCLIN B; CYCLIN D1; CYCLINE; CYTOCHROME C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIMONOID; NIMBOLIDE; PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; SURVIVIN;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL NUCLEUS; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; DRUG SYNTHESIS; ENZYME RELEASE; HELA CELL; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN FAMILY; TRANSCRIPTION INITIATION;

ANTIOXIDANTS; APOPTOSIS; AZADIRACHTA; BLOTTING, WESTERN; CELL CYCLE; CELL SURVIVAL; GENE EXPRESSION; HELA CELLS; HUMANS; LIMONINS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; POLYMERASE CHAIN REACTION; REACTIVE OXYGEN SPECIES;

AZADIRACHTA INDICA;

EID: 77953607616     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715761003692503     Document Type: Article

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