SIRT1 Activating compounds reduce oxidative stress mediated neuronal loss in viral induced CNS demyelinating disease

Acta Neuropathologica Communications

Volumn 2, Issue 1, 2014, Pages

  Khan, Reas S ^a   Dine, Kimberly ^a   Das Sarma, Jayasri ^b   Shindler, Kenneth S ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b INDIAN INSTITUTE OF SCIENCE EDUCATION AND RESEARCH KOLKATA   (India)

Author keywords

Demyelinating disease; Mouse hepatitis virus; Neuroprotection; Optic neuropathy; Oxidative stress; SIRT1

Indexed keywords

2-HYDROXY-4,4'-DIAMIDINOSTILBENE, METHANESULFONATE SALT; 6-CHLORO-2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-1-CARBOXAMIDE; CARBAZOLE DERIVATIVE; SIRT1 PROTEIN, MOUSE; SIRTUIN 1; STILBAMIDINE;

ANALYSIS OF VARIANCE; ANIMAL; ANIMAL HEPATITIS; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; COMPLICATION; DEMYELINATING AUTOIMMUNE DISEASES, CNS; DIAGNOSTIC USE; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; FEMALE; GENETICS; HEPATITIS VIRUS; METABOLISM; MOUSE; NERVE CELL; OXIDATIVE STRESS; PATHOGENICITY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TIME; VIROLOGY;

ANALYSIS OF VARIANCE; ANIMALS; CARBAZOLES; DEMYELINATING AUTOIMMUNE DISEASES, CNS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEPATITIS VIRUSES; HEPATITIS, VIRAL, ANIMAL; MICE; MICE, INBRED C57BL; NEURONS; OXIDATIVE STRESS; SIRTUIN 1; STILBAMIDINES; TIME FACTORS;

EID: 84921362253     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/2051-5960-2-3     Document Type: Article

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