Retinal nerve fiber layer axonal loss and visual dysfunction in optic neuritis

Annals of Neurology

Volumn 58, Issue 3, 2005, Pages 383-391

  Trip, S Anand ^a,b   Schlottmann, Patricio G ^b   Jones, Stephen J ^c   Altmann, Daniel R ^a,d   Garway Heath, David F ^b   Thompson, Alan J ^a   Plant, Gordon T ^b   Miller, David H ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b MOORFIELDS EYE HOSPITAL   (United Kingdom)

^c NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^d LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANALYZER; ARTICLE; CELL LOSS; CLINICAL ARTICLE; COLOR VISION; CONTROLLED STUDY; DISABILITY; DISEASE MARKER; ELECTRODE; ELECTROPHYSIOLOGY; EVOKED VISUAL RESPONSE; FEMALE; HUMAN; IMAGING SYSTEM; MALE; MULTIPLE SCLEROSIS; NEUROPROTECTION; OPTIC NERVE DISEASE; OPTICAL COHERENCE TOMOGRAPHY; PRIORITY JOURNAL; RELAPSE; RETINA GANGLION CELL; RETINA MACULA LUTEA; RETINA NERVE CELL; RETINA NERVE FIBER LAYER; THICKNESS; VISION TEST; VISUAL ACUITY; VISUAL DISORDER; VISUAL FIELD;

ADULT; AXONS; EVOKED POTENTIALS, VISUAL; FEMALE; HUMANS; MALE; MIDDLE AGED; NERVE FIBERS; OPTIC NEURITIS; RETINA; RETINAL GANGLION CELLS; TOMOGRAPHY, OPTICAL COHERENCE; VISION DISORDERS; VISUAL ACUITY;

EID: 24644501648     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/ana.20575     Document Type: Article

References (38)

1. Beck RW, Cleaty PA. Optic neuritis treatment trial. One-year follow-up results. Arch Ophthalmol 1993;111:773-775.
2. Beck RW, Gal RL, Bhatti MT, et al. Visual function more than 10 years after optic neuritis: experience of the optic neuritis treatment trial. Am J Ophthalmol 2004;137:77-83.
3. Gartner S. Optic neuropathy in multiple sclerosis. Arch Ophthalmol 1953;50:718-726.
4. Hickman SJ, Brex PA, Brierley CM, et al. Detection of optic nerve atrophy following a single episode of unilateral optic neuritis by MRI using a fat-saturated short-echo fast FLAIR sequence. Neuroradiology 2001;43:123-128.
5. Inglese M, Ghezzi A, Bianchi S, et al. Irreversible disability and tissue loss in multiple sclerosis: a conventional and magnetization transfer magnetic resonance imaging study of the optic nerves. Arch Neurol 2002;59:250-255.
6. Hickman SJ, Toosy AT, Jones SJ, et al. A serial MRI study following optic nerve mean area in acute optic neuritis. Brain 2004;127:2498-2505.
7. Sadun AA. Anatomy and physiology of the optic nerve. In: Miller NR, Newman NJ, eds. Walsh and Hoyt's clinical neuro-ophthalmology. 5th ed. Baltimore: Williams and Wilkins, 1998:57-83.
8. Ogden TE. Nerve fiber layer of the primate retina: thickness and glial content. Vision Res 1983;23:581-587.
9. Quigley HA, Davis EB, Anderson DR. Descending optic nerve degeneration in primates. Invest Ophthalmol Vis Sci 1977;16: 841-849.
10. Huang D, Swanson EA, Lin CP, et al. Optical coherence tomography. Science 1991;254:1178-1181.
11. Percher AF, Hitzenberger CK, Drexler W, et al. In vivo optical coherence tomography. Am J Ophthalmol 1993;116:113-114.
12. Kanamori A, Nakamura M, Escano MF, et al. Evaluation of the glaucomatous damage on retinal nerve fiber layer thickness measured by optical coherence tomography. Am J Ophthalmol 2003;135:513-520.
13. Parisi V, Manni G, Spadaro M, et al. Correlation between morphological and functional retinal impairment in multiple sclerosis patients. Invest Ophthalmol Vis Sci 1999;40:2520-2527.
14. Paunescu LA, Schuman JS, Price LL, et al. Reproducibility of nerve fiber thickness, macular thickness, and optic nerve head measurements using StratusOCT. Invest Ophthalmol Vis Sci 2004;45:1716-1724.
15. Ferris FL III, Kassoff A, Bresnick GH, et al. New visual acuity charts for clinical research. Am J Ophthalmol 1982;94:91-96.
16. Garway-Heath DF, Poinoosawmy D, Fitzke FW, et al. Mapping the visual field to the optic disc in normal tension glaucoma eyes. Ophthalmology 2000;107:1809-1815.
17. Farnsworth D. The Farnsworth-Munsell 100-hue and dichotomous tests for color vision. J Opt Soc Am 1943;33:568-578.
18. Brusa A, Jones SJ, Plant GT. Long-term remyelination after optic neuritis: a 2-year visual evoked potential and psychophysical serial study. Brain 2001;124:468-479.
19. Alamouti B, Funk J. Retinal thickness decreases with age: an OCT study. Br J Ophthalmol 2003;87:899-901.
20. Beck RW, Kupersmith MJ, Cleary PA, et al. Fellow eye abnormalities in acute unilateral optic neuritis. Experience of the optic neuritis treatment trial. Ophthalmology 1993;100:691-697.
21. Garway-Heath DF, Caprioli J, Fitzke FW, et al. Scaling the hill of vision: the physiological relationship between light sensitivity and ganglion cell numbers. Invest Ophthalmol Vis Sci 2000; 41:1774-1782.
22. Frisen L, Hoyt WF. Insidious atrophy of retinal nerve fibers in multiple sclerosis. Funduscopic identification in patients with and without visual complaints. Arch Ophthalmol 1974;92: 91-97.
23. Trapp BD, Peterson J, Ransohoff RM, et al. Axonal transection in the lesions of multiple sclerosis. N Engl J Med 1998;338: 278-285.
24. Kerrison JB, Flynn T, Green WR. Retinal pathologic changes in multiple sclerosis. Retina 1994;14:445-451.
25. Trobe JD, Glaser JS, Cassady JC. Optic atrophy, Differential diagnosis by fundus observation alone. Arch Ophthalmol 1980; 98:1040-1045.
26. MacFadyen DJ, Drance SM, Douglas GR, et al. The retinal nerve fiber layer, neuroretinal rim area, and visual evoked potentials in MS. Neurology 1988;38:1353-1358.
27. Elbol P, Work K. Retinal nerve fiber layer in multiple sclerosis. Acta Ophthalmol (Copenh) 1990;68:481-486.
28. Schlottmann PG, De Cilla S, Greenfield DS, et al. Relationship between visual field sensitivity and retinal nerve fiber layer thickness as measured by scanning laser polarimetry. Invest Ophthalmol Vis Sci 2004;45:1823-1829.
29. Dichtl A, Jonas JB, Naumann GO. Retinal nerve fiber layer thickness in human eyes. Graefes Arch Clin Exp Ophthalmol 1999;237:474-479.
30. Hood DC, Odel JG, Winn BJ. The multifocal visual evoked potential, J Neuroophthalmol 2003;23:279-289.
31. Hornabrook RS, Miller DH, Newton MR, et al, Frequenr involvement of the optic radiation in patients with acute isolated optic neuritis. Neurology 1992;42:77-79.
32. Ciccarelli O, Toosy AT, Hickman SJ, et al. Optic radiation changes after optic neuritis detected by tractography-based group mapping. Hum Brain Mapp 2005;25: 308-316.
33. Werring DJ, Bullmore ET, Toosy AT, et al. Recovery from optic neuritis is associated with a change in the distribution of cerebral response to visual stimulation: a functional magnetic resonance imaging study. J Neurol Neurosurg Psychiatry 2000; 68:441-449.
34. Toosy AT, Hickman SJ, Miszkiel KA, et ah Adaptive cortical plasticity in higher visual areas after acute optic neuritis, Ann Neurol 2005;57:622-633.
35. Jones SJ, Brusa A, Neurophysiological evidence for long-term repair of MS lesions: implications for axon protection. J Neurol Sci 2003;206:193-198.
36. Smith KJ, Kapoor R, Hall SM, et al. Electrically active axons degenerate when exposed to nitric oxide. Ann Neurol 2001;49: 470-476,
37. Holder GE, The incidence of abnormal pattern electroretinography in optic nerve demyelination, Electroencephalogr Clin Neurophysiol 1991;78:18-26.
38. Poser CM, Paty DW, Scheinberg L, et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983;13:227-231.