-
1
-
-
84869118116
-
Keratins and disease at a glance
-
Haines R.L., Lane E.B. Keratins and disease at a glance. J Cell Sci 2012, 125:3923-3928.
-
(2012)
J Cell Sci
, vol.125
, pp. 3923-3928
-
-
Haines, R.L.1
Lane, E.B.2
-
2
-
-
84873731727
-
The expanding significance of keratin intermediate filaments in normal and diseased epithelia
-
Pan X., Hobbs R.P., Coulombe P.A. The expanding significance of keratin intermediate filaments in normal and diseased epithelia. Curr Opin Cell Biol 2013, 25:47-56.
-
(2013)
Curr Opin Cell Biol
, vol.25
, pp. 47-56
-
-
Pan, X.1
Hobbs, R.P.2
Coulombe, P.A.3
-
3
-
-
84902466914
-
Beyond expectations: novel insights into epidermal keratin function and regulation
-
Homberg M., Magin T.M. Beyond expectations: novel insights into epidermal keratin function and regulation. Int Rev Cell Mol Biol 2014, 311:265-306.
-
(2014)
Int Rev Cell Mol Biol
, vol.311
, pp. 265-306
-
-
Homberg, M.1
Magin, T.M.2
-
4
-
-
84894576158
-
Post-translational modifications of intermediate filament proteins: mechanisms and functions
-
Snider N.T., Omary M.B. Post-translational modifications of intermediate filament proteins: mechanisms and functions. Nat Rev Mol Cell Biol 2014, 15:163-177.
-
(2014)
Nat Rev Mol Cell Biol
, vol.15
, pp. 163-177
-
-
Snider, N.T.1
Omary, M.B.2
-
5
-
-
34249805712
-
Hair follicle-specific keratins and their diseases
-
Schweizer J., Langbein L., Rogers M.A., Winter H. Hair follicle-specific keratins and their diseases. Exp Cell Res 2007, 313:2010-2020.
-
(2007)
Exp Cell Res
, vol.313
, pp. 2010-2020
-
-
Schweizer, J.1
Langbein, L.2
Rogers, M.A.3
Winter, H.4
-
6
-
-
68849111162
-
Toward unraveling the complexity of simple epithelial keratins in human disease
-
Omary M.B., Ku N.O., Strnad P., Hanada S. Toward unraveling the complexity of simple epithelial keratins in human disease. J Clin Invest 2009, 119:1794-1805.
-
(2009)
J Clin Invest
, vol.119
, pp. 1794-1805
-
-
Omary, M.B.1
Ku, N.O.2
Strnad, P.3
Hanada, S.4
-
7
-
-
83155181586
-
Keratin disorders: from gene to therapy
-
McLean W.H., Moore C.B. Keratin disorders: from gene to therapy. Hum Mol Genet 2011, 20:R189-R197.
-
(2011)
Hum Mol Genet
, vol.20
, pp. R189-R197
-
-
McLean, W.H.1
Moore, C.B.2
-
8
-
-
84859885578
-
Keratins: markers and modulators of liver disease
-
Strnad P., Paschke S., Jang K.H., Ku N.O. Keratins: markers and modulators of liver disease. Curr Opin Gastroenterol 2012, 28:209-216.
-
(2012)
Curr Opin Gastroenterol
, vol.28
, pp. 209-216
-
-
Strnad, P.1
Paschke, S.2
Jang, K.H.3
Ku, N.O.4
-
9
-
-
84862776648
-
Defining keratin protein function in skin epithelia: epidermolysis bullosa simplex and its aftermath
-
Coulombe P.A., Lee C.H. Defining keratin protein function in skin epithelia: epidermolysis bullosa simplex and its aftermath. J Invest Dermatol 2012, 132:763-775.
-
(2012)
J Invest Dermatol
, vol.132
, pp. 763-775
-
-
Coulombe, P.A.1
Lee, C.H.2
-
10
-
-
68149170036
-
New common variants affecting susceptibility to basal cell carcinoma
-
Stacey S.N., Sulem P., Masson G., Gudjonsson S.A., Thorleifsson G., Jakobsdottir M., Sigurdsson A., Gudbjartsson D.F., Sigurgeirsson B., Benediktsdottir K.R., et al. New common variants affecting susceptibility to basal cell carcinoma. Nat Genet 2009, 41:909-914.
-
(2009)
Nat Genet
, vol.41
, pp. 909-914
-
-
Stacey, S.N.1
Sulem, P.2
Masson, G.3
Gudjonsson, S.A.4
Thorleifsson, G.5
Jakobsdottir, M.6
Sigurdsson, A.7
Gudbjartsson, D.F.8
Sigurgeirsson, B.9
Benediktsdottir, K.R.10
-
11
-
-
84863981085
-
Type 1 segmental Galli-Galli disease resulting from a previously unreported keratin 5 mutation
-
Arnold A.W., Kiritsi D., Happle R., Kohlhase J., Hausser I., Bruckner-Tuderman L., Has C., Itin P.H. Type 1 segmental Galli-Galli disease resulting from a previously unreported keratin 5 mutation. J Invest Dermatol 2012, 132:2100-2103.
-
(2012)
J Invest Dermatol
, vol.132
, pp. 2100-2103
-
-
Arnold, A.W.1
Kiritsi, D.2
Happle, R.3
Kohlhase, J.4
Hausser, I.5
Bruckner-Tuderman, L.6
Has, C.7
Itin, P.H.8
-
12
-
-
68849091625
-
Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility
-
Coulombe P.A., Kerns M.L., Fuchs E. Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility. J Clin Invest 2009, 119:1784-1793.
-
(2009)
J Clin Invest
, vol.119
, pp. 1784-1793
-
-
Coulombe, P.A.1
Kerns, M.L.2
Fuchs, E.3
-
13
-
-
79952682059
-
Keratin gene mutations in disorders of human skin and its appendages
-
Chamcheu J.C., Siddiqui I.A., Syed D.N., Adhami V.M., Liovic M., Mukhtar H. Keratin gene mutations in disorders of human skin and its appendages. Arch Biochem Biophys 2011, 508:123-137.
-
(2011)
Arch Biochem Biophys
, vol.508
, pp. 123-137
-
-
Chamcheu, J.C.1
Siddiqui, I.A.2
Syed, D.N.3
Adhami, V.M.4
Liovic, M.5
Mukhtar, H.6
-
14
-
-
33745628320
-
A disease- and phosphorylation-related nonmechanical function for keratin 8
-
Ku N.O., Omary M.B. A disease- and phosphorylation-related nonmechanical function for keratin 8. J Cell Biol 2006, 174:115-125.
-
(2006)
J Cell Biol
, vol.174
, pp. 115-125
-
-
Ku, N.O.1
Omary, M.B.2
-
15
-
-
84856826693
-
Unique amino acid signatures that are evolutionarily conserved distinguish simple-type, epidermal and hair keratins
-
Strnad P., Usachov V., Debes C., Grater F., Parry D.A., Omary M.B. Unique amino acid signatures that are evolutionarily conserved distinguish simple-type, epidermal and hair keratins. J Cell Sci 2011, 124:4221-4232.
-
(2011)
J Cell Sci
, vol.124
, pp. 4221-4232
-
-
Strnad, P.1
Usachov, V.2
Debes, C.3
Grater, F.4
Parry, D.A.5
Omary, M.B.6
-
16
-
-
78751534200
-
Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation
-
Snider N.T., Weerasinghe S.V., Iniguez-Lluhi J.A., Herrmann H., Omary M.B. Keratin hypersumoylation alters filament dynamics and is a marker for human liver disease and keratin mutation. J Biol Chem 2011, 286:2273-2284.
-
(2011)
J Biol Chem
, vol.286
, pp. 2273-2284
-
-
Snider, N.T.1
Weerasinghe, S.V.2
Iniguez-Lluhi, J.A.3
Herrmann, H.4
Omary, M.B.5
-
17
-
-
75149145548
-
Intermediate filaments take the heat as stress proteins
-
Toivola D.M., Strnad P., Habtezion A., Omary M.B. Intermediate filaments take the heat as stress proteins. Trends Cell Biol 2010, 20:79-91.
-
(2010)
Trends Cell Biol
, vol.20
, pp. 79-91
-
-
Toivola, D.M.1
Strnad, P.2
Habtezion, A.3
Omary, M.B.4
-
18
-
-
78651397689
-
Keratins in health and cancer: more than mere epithelial cell markers
-
Karantza V. Keratins in health and cancer: more than mere epithelial cell markers. Oncogene 2011, 30:127-138.
-
(2011)
Oncogene
, vol.30
, pp. 127-138
-
-
Karantza, V.1
-
19
-
-
44149099717
-
The human keratins: biology and pathology
-
Moll R., Divo M., Langbein L. The human keratins: biology and pathology. Histochem Cell Biol 2008, 129:705-733.
-
(2008)
Histochem Cell Biol
, vol.129
, pp. 705-733
-
-
Moll, R.1
Divo, M.2
Langbein, L.3
-
20
-
-
84879216747
-
Broad-spectrum immunohistochemical epithelial markers: a review
-
Ordonez N.G. Broad-spectrum immunohistochemical epithelial markers: a review. Hum Pathol 2013, 44:1195-1215.
-
(2013)
Hum Pathol
, vol.44
, pp. 1195-1215
-
-
Ordonez, N.G.1
-
21
-
-
84867011582
-
Diagnostic utility of immunohistochemistry in distinguishing trichoepithelioma and basal cell carcinoma: evaluation using tissue microarray samples
-
Tebcherani A.J., de Andrade H.F., Sotto M.N. Diagnostic utility of immunohistochemistry in distinguishing trichoepithelioma and basal cell carcinoma: evaluation using tissue microarray samples. Mod Pathol 2012, 25:1345-1353.
-
(2012)
Mod Pathol
, vol.25
, pp. 1345-1353
-
-
Tebcherani, A.J.1
de Andrade, H.F.2
Sotto, M.N.3
-
22
-
-
84862789588
-
Loss of keratin 13 in oral carcinoma in situ: a comparative study of protein and gene expression levels using paraffin sections
-
Ida-Yonemochi H., Maruyama S., Kobayashi T., Yamazaki M., Cheng J., Saku T. Loss of keratin 13 in oral carcinoma in situ: a comparative study of protein and gene expression levels using paraffin sections. Mod Pathol 2012, 25:784-794.
-
(2012)
Mod Pathol
, vol.25
, pp. 784-794
-
-
Ida-Yonemochi, H.1
Maruyama, S.2
Kobayashi, T.3
Yamazaki, M.4
Cheng, J.5
Saku, T.6
-
23
-
-
84857134689
-
Three differentiation states risk-stratify bladder cancer into distinct subtypes
-
Volkmer J.P., Sahoo D., Chin R.K., Ho P.L., Tang C., Kurtova A.V., Willingham S.B., Pazhanisamy S.K., Contreras-Trujillo H., Storm T.A., et al. Three differentiation states risk-stratify bladder cancer into distinct subtypes. Proc Natl Acad Sci USA 2012, 109:2078-2083.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 2078-2083
-
-
Volkmer, J.P.1
Sahoo, D.2
Chin, R.K.3
Ho, P.L.4
Tang, C.5
Kurtova, A.V.6
Willingham, S.B.7
Pazhanisamy, S.K.8
Contreras-Trujillo, H.9
Storm, T.A.10
-
24
-
-
84863982081
-
Molecular insights on basal-like breast cancer
-
Valentin M.D., da Silva S.D., Privat M., Alaoui-Jamali M., Bignon Y.J. Molecular insights on basal-like breast cancer. Breast Cancer Res Treat 2012, 134:21-30.
-
(2012)
Breast Cancer Res Treat
, vol.134
, pp. 21-30
-
-
Valentin, M.D.1
da Silva, S.D.2
Privat, M.3
Alaoui-Jamali, M.4
Bignon, Y.J.5
-
25
-
-
84878069977
-
Identification of prognosis-relevant subgroups in patients with chemoresistant triple-negative breast cancer
-
Yu K.D., Zhu R., Zhan M., Rodriguez A.A., Yang W., Wong S., Makris A., Lehmann B.D., Chen X., Mayer I., et al. Identification of prognosis-relevant subgroups in patients with chemoresistant triple-negative breast cancer. Clin Cancer Res 2013, 19:2723-2733.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 2723-2733
-
-
Yu, K.D.1
Zhu, R.2
Zhan, M.3
Rodriguez, A.A.4
Yang, W.5
Wong, S.6
Makris, A.7
Lehmann, B.D.8
Chen, X.9
Mayer, I.10
-
26
-
-
80055060696
-
Human hepatocellular carcinomas with Stemness-related marker expression: keratin 19 expression and a poor prognosis
-
Kim H., Choi G.H., Na D.C., Ahn E.Y., Kim G.I., Lee J.E., Cho J.Y., Yoo J.E., Choi J.S., Park Y.N. Human hepatocellular carcinomas with Stemness-related marker expression: keratin 19 expression and a poor prognosis. Hepatology 2011, 54:1707-1717.
-
(2011)
Hepatology
, vol.54
, pp. 1707-1717
-
-
Kim, H.1
Choi, G.H.2
Na, D.C.3
Ahn, E.Y.4
Kim, G.I.5
Lee, J.E.6
Cho, J.Y.7
Yoo, J.E.8
Choi, J.S.9
Park, Y.N.10
-
27
-
-
84895435815
-
Keratin 19: a key role player in the invasion of human hepatocellular carcinomas
-
Govaere O., Komuta M., Berkers J., Spee B., Janssen C., de Luca F., Katoonizadeh A., Wouters J., van Kempen L.C., Durnez A., et al. Keratin 19: a key role player in the invasion of human hepatocellular carcinomas. Gut 2014, 63:674-685.
-
(2014)
Gut
, vol.63
, pp. 674-685
-
-
Govaere, O.1
Komuta, M.2
Berkers, J.3
Spee, B.4
Janssen, C.5
de Luca, F.6
Katoonizadeh, A.7
Wouters, J.8
van Kempen, L.C.9
Durnez, A.10
-
28
-
-
84868195394
-
Background progenitor activation is associated with recurrence after hepatectomy of combined hepatocellular-cholangiocarcinoma
-
Cai X., Zhai J., Kaplan D.E., Zhang Y., Zhou L., Chen X., Qian G., Zhao Q., Li Y., Gao L., et al. Background progenitor activation is associated with recurrence after hepatectomy of combined hepatocellular-cholangiocarcinoma. Hepatology 2012, 56:1804-1816.
-
(2012)
Hepatology
, vol.56
, pp. 1804-1816
-
-
Cai, X.1
Zhai, J.2
Kaplan, D.E.3
Zhang, Y.4
Zhou, L.5
Chen, X.6
Qian, G.7
Zhao, Q.8
Li, Y.9
Gao, L.10
-
29
-
-
84897495974
-
Keratin 17 in premalignant and malignant squamous lesions of the cervix: proteomic discovery and immunohistochemical validation as a diagnostic and prognostic biomarker
-
Escobar-Hoyos L.F., Yang J., Zhu J., Cavallo J.A., Zhai H., Burke S., Koller A., Chen E.I., Shroyer K.R. Keratin 17 in premalignant and malignant squamous lesions of the cervix: proteomic discovery and immunohistochemical validation as a diagnostic and prognostic biomarker. Mod Pathol 2014, 27:621-630.
-
(2014)
Mod Pathol
, vol.27
, pp. 621-630
-
-
Escobar-Hoyos, L.F.1
Yang, J.2
Zhu, J.3
Cavallo, J.A.4
Zhai, H.5
Burke, S.6
Koller, A.7
Chen, E.I.8
Shroyer, K.R.9
-
30
-
-
84868207596
-
Keratin 17 expression correlates with tumor progression and poor prognosis in gastric adenocarcinoma
-
Ide M., Kato T., Ogata K., Mochiki E., Kuwano H., Oyama T. Keratin 17 expression correlates with tumor progression and poor prognosis in gastric adenocarcinoma. Ann Surg Oncol 2012, 19:3506-3514.
-
(2012)
Ann Surg Oncol
, vol.19
, pp. 3506-3514
-
-
Ide, M.1
Kato, T.2
Ogata, K.3
Mochiki, E.4
Kuwano, H.5
Oyama, T.6
-
31
-
-
84864361933
-
Association of cytokeratin 17 expression with differentiation in oral squamous cell carcinoma
-
Kitamura R., Toyoshima T., Tanaka H., Kawano S., Kiyosue T., Matsubara R., Goto Y., Hirano M., Oobu K., Nakamura S. Association of cytokeratin 17 expression with differentiation in oral squamous cell carcinoma. J Cancer Res Clin Oncol 2012, 138:1299-1310.
-
(2012)
J Cancer Res Clin Oncol
, vol.138
, pp. 1299-1310
-
-
Kitamura, R.1
Toyoshima, T.2
Tanaka, H.3
Kawano, S.4
Kiyosue, T.5
Matsubara, R.6
Goto, Y.7
Hirano, M.8
Oobu, K.9
Nakamura, S.10
-
32
-
-
84861448522
-
Persistent tumor cells in bone marrow of non-metastatic breast cancer patients after primary surgery are associated with inferior outcome
-
Tjensvoll K., Oltedal S., Heikkila R., Kvaloy J.T., Gilje B., Reuben J.M., Smaaland R., Nordgard O. Persistent tumor cells in bone marrow of non-metastatic breast cancer patients after primary surgery are associated with inferior outcome. BMC Cancer 2012, 12:190.
-
(2012)
BMC Cancer
, vol.12
, pp. 190
-
-
Tjensvoll, K.1
Oltedal, S.2
Heikkila, R.3
Kvaloy, J.T.4
Gilje, B.5
Reuben, J.M.6
Smaaland, R.7
Nordgard, O.8
-
33
-
-
84867403245
-
Whole sentinel lymph node analysis by a molecular assay predicts axillary node status in breast cancer
-
Ohi Y., Umekita Y., Sagara Y., Rai Y., Yotsumoto D., Matsukata A., Baba S., Tamada S., Matsuyama Y., Ando M., et al. Whole sentinel lymph node analysis by a molecular assay predicts axillary node status in breast cancer. Br J Cancer 2012, 107:1239-1243.
-
(2012)
Br J Cancer
, vol.107
, pp. 1239-1243
-
-
Ohi, Y.1
Umekita, Y.2
Sagara, Y.3
Rai, Y.4
Yotsumoto, D.5
Matsukata, A.6
Baba, S.7
Tamada, S.8
Matsuyama, Y.9
Ando, M.10
-
34
-
-
84875732982
-
Sentinel node tumour burden quantified based on cytokeratin 19 mRNA copy number predicts non-sentinel node metastases in breast cancer: molecular whole-node analysis of all removed nodes
-
Osako T., Iwase T., Kimura K., Horii R., Akiyama F. Sentinel node tumour burden quantified based on cytokeratin 19 mRNA copy number predicts non-sentinel node metastases in breast cancer: molecular whole-node analysis of all removed nodes. Eur J Cancer 2013, 49:1187-1195.
-
(2013)
Eur J Cancer
, vol.49
, pp. 1187-1195
-
-
Osako, T.1
Iwase, T.2
Kimura, K.3
Horii, R.4
Akiyama, F.5
-
35
-
-
84929465334
-
One-step nucleic acid amplification assay (OSNA) for sentinel lymph node biopsy
-
Tamaki Y. One-step nucleic acid amplification assay (OSNA) for sentinel lymph node biopsy. Breast Cancer 2012, 10.1007/s12282-012-0390-x.
-
(2012)
Breast Cancer
-
-
Tamaki, Y.1
-
36
-
-
84863325178
-
Routine clinical use of the one-step nucleic acid amplification assay for detection of sentinel lymph node metastases in breast cancer patients: results of a multicenter study in Japan
-
Tamaki Y., Sato N., Homma K., Takabatake D., Nishimura R., Tsujimoto M., Yoshidome K., Tsuda H., Kinoshita T., Kato H., et al. Routine clinical use of the one-step nucleic acid amplification assay for detection of sentinel lymph node metastases in breast cancer patients: results of a multicenter study in Japan. Cancer 2012, 118:3477-3483.
-
(2012)
Cancer
, vol.118
, pp. 3477-3483
-
-
Tamaki, Y.1
Sato, N.2
Homma, K.3
Takabatake, D.4
Nishimura, R.5
Tsujimoto, M.6
Yoshidome, K.7
Tsuda, H.8
Kinoshita, T.9
Kato, H.10
-
37
-
-
84857370817
-
Intraoperative analysis of sentinel lymph nodes in breast cancer by one-step nucleic acid amplification
-
Cserni G. Intraoperative analysis of sentinel lymph nodes in breast cancer by one-step nucleic acid amplification. J Clin Pathol 2012, 65:193-199.
-
(2012)
J Clin Pathol
, vol.65
, pp. 193-199
-
-
Cserni, G.1
-
38
-
-
84872017586
-
Circulating tumor cells: liquid biopsy of cancer
-
Alix-Panabieres C., Pantel K. Circulating tumor cells: liquid biopsy of cancer. Clin Chem 2013, 59:110-118.
-
(2013)
Clin Chem
, vol.59
, pp. 110-118
-
-
Alix-Panabieres, C.1
Pantel, K.2
-
39
-
-
84861552046
-
Detection of circulating tumor cells in blood of metastatic breast cancer patients using a combination of cytokeratin and EpCAM antibodies
-
Weissenstein U., Schumann A., Reif M., Link S., Toffol-Schmidt U.D., Heusser P. Detection of circulating tumor cells in blood of metastatic breast cancer patients using a combination of cytokeratin and EpCAM antibodies. BMC Cancer 2012, 12:206.
-
(2012)
BMC Cancer
, vol.12
, pp. 206
-
-
Weissenstein, U.1
Schumann, A.2
Reif, M.3
Link, S.4
Toffol-Schmidt, U.D.5
Heusser, P.6
-
40
-
-
7944221186
-
The keratin cytoskeleton in liver diseases
-
Zatloukal K., Stumptner C., Fuchsbichler A., Fickert P., Lackner C., Trauner M., Denk H. The keratin cytoskeleton in liver diseases. J Pathol 2004, 204:367-376.
-
(2004)
J Pathol
, vol.204
, pp. 367-376
-
-
Zatloukal, K.1
Stumptner, C.2
Fuchsbichler, A.3
Fickert, P.4
Lackner, C.5
Trauner, M.6
Denk, H.7
-
41
-
-
84873301884
-
Keratin 19 demonstration of canal of Hering loss in primary biliary cirrhosis: minimal change PBC?
-
Khan F.M., Komarla A.R., Mendoza P.G., Bodenheimer H.C., Theise N.D. Keratin 19 demonstration of canal of Hering loss in primary biliary cirrhosis: minimal change PBC?. Hepatology 2013, 57:700-707.
-
(2013)
Hepatology
, vol.57
, pp. 700-707
-
-
Khan, F.M.1
Komarla, A.R.2
Mendoza, P.G.3
Bodenheimer, H.C.4
Theise, N.D.5
-
42
-
-
84861576624
-
Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis
-
Sancho-Bru P., Altamirano J., Rodrigo-Torres D., Coll M., Millan C., Jose Lozano J., Miquel R., Arroyo V., Caballeria J., Gines P., et al. Liver progenitor cell markers correlate with liver damage and predict short-term mortality in patients with alcoholic hepatitis. Hepatology 2012, 55:1931-1941.
-
(2012)
Hepatology
, vol.55
, pp. 1931-1941
-
-
Sancho-Bru, P.1
Altamirano, J.2
Rodrigo-Torres, D.3
Coll, M.4
Millan, C.5
Jose Lozano, J.6
Miquel, R.7
Arroyo, V.8
Caballeria, J.9
Gines, P.10
-
43
-
-
84864367149
-
A morphometric and immunohistochemical study to assess the benefit of a sustained virological response in hepatitis C virus patients with cirrhosis
-
D'Ambrosio R., Aghemo A., Rumi M.G., Ronchi G., Donato M.F., Paradis V., Colombo M., Bedossa P. A morphometric and immunohistochemical study to assess the benefit of a sustained virological response in hepatitis C virus patients with cirrhosis. Hepatology 2012, 56:532-543.
-
(2012)
Hepatology
, vol.56
, pp. 532-543
-
-
D'Ambrosio, R.1
Aghemo, A.2
Rumi, M.G.3
Ronchi, G.4
Donato, M.F.5
Paradis, V.6
Colombo, M.7
Bedossa, P.8
-
44
-
-
84861200682
-
Costaining for keratins 8/18 plus ubiquitin improves detection of hepatocyte injury in nonalcoholic fatty liver disease
-
Guy C.D., Suzuki A., Burchette J.L., Brunt E.M., Abdelmalek M.F., Cardona D., McCall S.J., Unalp A., Belt P., Ferrell L.D., et al. Costaining for keratins 8/18 plus ubiquitin improves detection of hepatocyte injury in nonalcoholic fatty liver disease. Hum Pathol 2012, 43:790-800.
-
(2012)
Hum Pathol
, vol.43
, pp. 790-800
-
-
Guy, C.D.1
Suzuki, A.2
Burchette, J.L.3
Brunt, E.M.4
Abdelmalek, M.F.5
Cardona, D.6
McCall, S.J.7
Unalp, A.8
Belt, P.9
Ferrell, L.D.10
-
45
-
-
84887454672
-
Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis
-
Yang I.V., Coldren C.D., Leach S.M., Seibold M.A., Murphy E., Lin J., Rosen R., Neidermyer A.J., McKean D.F., Groshong S.D., et al. Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis. Thorax 2013, 68:1114-1121.
-
(2013)
Thorax
, vol.68
, pp. 1114-1121
-
-
Yang, I.V.1
Coldren, C.D.2
Leach, S.M.3
Seibold, M.A.4
Murphy, E.5
Lin, J.6
Rosen, R.7
Neidermyer, A.J.8
McKean, D.F.9
Groshong, S.D.10
-
46
-
-
84871367567
-
Preoperative serum tissue polypeptide-specific antigen is a valuable prognostic marker in breast cancer
-
Ahn S.K., Moon H.G., Ko E., Kim H.S., Shin H.C., Kim J., You J.M., Han W., Noh D.Y. Preoperative serum tissue polypeptide-specific antigen is a valuable prognostic marker in breast cancer. Int J Cancer 2013, 132:875-881.
-
(2013)
Int J Cancer
, vol.132
, pp. 875-881
-
-
Ahn, S.K.1
Moon, H.G.2
Ko, E.3
Kim, H.S.4
Shin, H.C.5
Kim, J.6
You, J.M.7
Han, W.8
Noh, D.Y.9
-
47
-
-
84867902482
-
Multi-level evidence that circulating CK18 is a biomarker of tumour burden in colorectal cancer
-
Greystoke A., Dean E., Saunders M.P., Cummings J., Hughes A., Ranson M., Dive C., Renehan A.G. Multi-level evidence that circulating CK18 is a biomarker of tumour burden in colorectal cancer. Br J Cancer 2012, 107:1518-1524.
-
(2012)
Br J Cancer
, vol.107
, pp. 1518-1524
-
-
Greystoke, A.1
Dean, E.2
Saunders, M.P.3
Cummings, J.4
Hughes, A.5
Ranson, M.6
Dive, C.7
Renehan, A.G.8
-
48
-
-
33748064683
-
Tumor markers in detection of lung cancer
-
Schneider J. Tumor markers in detection of lung cancer. Adv Clin Chem 2006, 42:1-41.
-
(2006)
Adv Clin Chem
, vol.42
, pp. 1-41
-
-
Schneider, J.1
-
49
-
-
84881027019
-
Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital
-
Antoine D.J., Dear J.W., Lewis P.S., Platt V., Coyle J., Masson M., Thanacoody R.H., Gray A.J., Webb D.J., Moggs J.G., et al. Mechanistic biomarkers provide early and sensitive detection of acetaminophen-induced acute liver injury at first presentation to hospital. Hepatology 2013, 58:777-787.
-
(2013)
Hepatology
, vol.58
, pp. 777-787
-
-
Antoine, D.J.1
Dear, J.W.2
Lewis, P.S.3
Platt, V.4
Coyle, J.5
Masson, M.6
Thanacoody, R.H.7
Gray, A.J.8
Webb, D.J.9
Moggs, J.G.10
-
50
-
-
84856388968
-
Prospective biopsy-controlled evaluation of cell death biomarkers for prediction of liver fibrosis and nonalcoholic steatohepatitis
-
Joka D., Wahl K., Moeller S., Schlue J., Vaske B., Bahr M.J., Manns M.P., Schulze-Osthoff K., Bantel H. Prospective biopsy-controlled evaluation of cell death biomarkers for prediction of liver fibrosis and nonalcoholic steatohepatitis. Hepatology 2012, 55:455-464.
-
(2012)
Hepatology
, vol.55
, pp. 455-464
-
-
Joka, D.1
Wahl, K.2
Moeller, S.3
Schlue, J.4
Vaske, B.5
Bahr, M.J.6
Manns, M.P.7
Schulze-Osthoff, K.8
Bantel, H.9
-
51
-
-
84868014401
-
Development of an accurate index for predicting outcomes of patients with acute liver failure
-
Rutherford A., King L.Y., Hynan L.S., Vedvyas C., Lin W., Lee W.M., Chung R.T. Development of an accurate index for predicting outcomes of patients with acute liver failure. Gastroenterology 2012, 143:1237-1243.
-
(2012)
Gastroenterology
, vol.143
, pp. 1237-1243
-
-
Rutherford, A.1
King, L.Y.2
Hynan, L.S.3
Vedvyas, C.4
Lin, W.5
Lee, W.M.6
Chung, R.T.7
-
52
-
-
84883740164
-
Serum cytokeratin-18 fragment levels are useful biomarkers for nonalcoholic steatohepatitis in children
-
Feldstein A.E., Alkhouri N., De Vito R., Alisi A., Lopez R., Nobili V. Serum cytokeratin-18 fragment levels are useful biomarkers for nonalcoholic steatohepatitis in children. Am J Gastroenterol 2013, 108:1526-1531.
-
(2013)
Am J Gastroenterol
, vol.108
, pp. 1526-1531
-
-
Feldstein, A.E.1
Alkhouri, N.2
De Vito, R.3
Alisi, A.4
Lopez, R.5
Nobili, V.6
-
53
-
-
44149085177
-
Monitoring of epithelial cell caspase activation via detection of durable keratin fragment formation
-
Tao G.Z., Li D.H., Zhou Q., Toivola D.M., Strnad P., Sandesara N., Cheung R.C., Hong A., Omary M.B. Monitoring of epithelial cell caspase activation via detection of durable keratin fragment formation. J Pathol 2008, 215:164-174.
-
(2008)
J Pathol
, vol.215
, pp. 164-174
-
-
Tao, G.Z.1
Li, D.H.2
Zhou, Q.3
Toivola, D.M.4
Strnad, P.5
Sandesara, N.6
Cheung, R.C.7
Hong, A.8
Omary, M.B.9
-
54
-
-
84890547086
-
Limited value of plasma cytokeratin-18 as a biomarker for NASH and fibrosis in patients with non-alcoholic fatty liver disease
-
Cusi K., Chang Z., Harrison S., Lomonaco R., Bril F., Orsak B., Ortiz-Lopez C., Hecht J., Feldstein A.E., Webb A., et al. Limited value of plasma cytokeratin-18 as a biomarker for NASH and fibrosis in patients with non-alcoholic fatty liver disease. J Hepatol 2014, 60:167-174.
-
(2014)
J Hepatol
, vol.60
, pp. 167-174
-
-
Cusi, K.1
Chang, Z.2
Harrison, S.3
Lomonaco, R.4
Bril, F.5
Orsak, B.6
Ortiz-Lopez, C.7
Hecht, J.8
Feldstein, A.E.9
Webb, A.10
-
55
-
-
84924568000
-
Keratins 8 and 18 are type II acute-phase responsive genes overexpressed in human liver disease
-
Guldiken N., Usachov V., Levada K., Trautwein C., Ziol M., Nahon P., Strnad P. Keratins 8 and 18 are type II acute-phase responsive genes overexpressed in human liver disease. Liver Int 2014, 10.1111/liv.12608.
-
(2014)
Liver Int
-
-
Guldiken, N.1
Usachov, V.2
Levada, K.3
Trautwein, C.4
Ziol, M.5
Nahon, P.6
Strnad, P.7
-
56
-
-
84899750869
-
High-fat diet triggers Mallory-Denk body formation through misfolding and crosslinking of excess keratin 8
-
Kucukoglu O., Guldiken N., Chen Y., Usachov V., El-Heliebi A., Haybaeck J., Denk H., Trautwein C., Strnad P. High-fat diet triggers Mallory-Denk body formation through misfolding and crosslinking of excess keratin 8. Hepatology 2014, 60:169-178.
-
(2014)
Hepatology
, vol.60
, pp. 169-178
-
-
Kucukoglu, O.1
Guldiken, N.2
Chen, Y.3
Usachov, V.4
El-Heliebi, A.5
Haybaeck, J.6
Denk, H.7
Trautwein, C.8
Strnad, P.9
-
57
-
-
84861790466
-
Keratin 8 phosphorylation regulates its transamidation and hepatocyte Mallory-Denk body formation
-
Kwan R., Hanada S., Harada M., Strnad P., Li D.H., Omary M.B. Keratin 8 phosphorylation regulates its transamidation and hepatocyte Mallory-Denk body formation. FASEB J 2012, 26:2318-2326.
-
(2012)
FASEB J
, vol.26
, pp. 2318-2326
-
-
Kwan, R.1
Hanada, S.2
Harada, M.3
Strnad, P.4
Li, D.H.5
Omary, M.B.6
-
58
-
-
84863511960
-
Oxidative stress, Nrf2 and keratin up-regulation associate with Mallory-Denk body formation in mouse erythropoietic protoporphyria
-
Singla A., Moons D.S., Snider N.T., Wagenmaker E.R., Jayasundera V.B., Omary M.B. Oxidative stress, Nrf2 and keratin up-regulation associate with Mallory-Denk body formation in mouse erythropoietic protoporphyria. Hepatology 2012, 56:322-331.
-
(2012)
Hepatology
, vol.56
, pp. 322-331
-
-
Singla, A.1
Moons, D.S.2
Snider, N.T.3
Wagenmaker, E.R.4
Jayasundera, V.B.5
Omary, M.B.6
-
59
-
-
84862627407
-
A wound-induced keratin inhibits Src activity during keratinocyte migration and tissue repair
-
Rotty J.D., Coulombe P.A. A wound-induced keratin inhibits Src activity during keratinocyte migration and tissue repair. J Cell Biol 2012, 197:381-389.
-
(2012)
J Cell Biol
, vol.197
, pp. 381-389
-
-
Rotty, J.D.1
Coulombe, P.A.2
-
60
-
-
84867186262
-
Cytokeratins mediate epithelial innate defense through their antimicrobial properties
-
Tam C., Mun J.J., Evans D.J., Fleiszig S.M. Cytokeratins mediate epithelial innate defense through their antimicrobial properties. J Clin Invest 2012, 122:3665-3677.
-
(2012)
J Clin Invest
, vol.122
, pp. 3665-3677
-
-
Tam, C.1
Mun, J.J.2
Evans, D.J.3
Fleiszig, S.M.4
-
61
-
-
84888354152
-
Keratin 16 regulates innate immunity in response to epidermal barrier breach
-
Lessard J.C., Pina-Paz S., Rotty J.D., Hickerson R.P., Kaspar R.L., Balmain A., Coulombe P.A. Keratin 16 regulates innate immunity in response to epidermal barrier breach. Proc Natl Acad Sci USA 2013, 110:19537-19542.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 19537-19542
-
-
Lessard, J.C.1
Pina-Paz, S.2
Rotty, J.D.3
Hickerson, R.P.4
Kaspar, R.L.5
Balmain, A.6
Coulombe, P.A.7
-
62
-
-
33745003902
-
A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth
-
Kim S., Wong P., Coulombe P.A. A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth. Nature 2006, 441:362-365.
-
(2006)
Nature
, vol.441
, pp. 362-365
-
-
Kim, S.1
Wong, P.2
Coulombe, P.A.3
-
63
-
-
77957584091
-
Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin
-
Depianto D., Kerns M.L., Dlugosz A.A., Coulombe P.A. Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin. Nat Genet 2010, 42:910-914.
-
(2010)
Nat Genet
, vol.42
, pp. 910-914
-
-
Depianto, D.1
Kerns, M.L.2
Dlugosz, A.A.3
Coulombe, P.A.4
-
64
-
-
84895064450
-
Keratin 17: a critical player in the pathogenesis of psoriasis
-
Jin L., Wang G. Keratin 17: a critical player in the pathogenesis of psoriasis. Med Res Rev 2014, 34:438-454.
-
(2014)
Med Res Rev
, vol.34
, pp. 438-454
-
-
Jin, L.1
Wang, G.2
-
65
-
-
84886998616
-
A novel role for keratin 17 in coordinating oncogenic transformation and cellular adhesion in Ewing sarcoma
-
Sankar S., Tanner J.M., Bell R., Chaturvedi A., Randall R.L., Beckerle M.C., Lessnick S.L. A novel role for keratin 17 in coordinating oncogenic transformation and cellular adhesion in Ewing sarcoma. Mol Cell Biol 2013, 33:4448-4460.
-
(2013)
Mol Cell Biol
, vol.33
, pp. 4448-4460
-
-
Sankar, S.1
Tanner, J.M.2
Bell, R.3
Chaturvedi, A.4
Randall, R.L.5
Beckerle, M.C.6
Lessnick, S.L.7
-
66
-
-
84894581126
-
Collective invasion in breast cancer requires a conserved basal epithelial program
-
Cheung K.J., Gabrielson E., Werb Z., Ewald A.J. Collective invasion in breast cancer requires a conserved basal epithelial program. Cell 2013, 155:1639-1651.
-
(2013)
Cell
, vol.155
, pp. 1639-1651
-
-
Cheung, K.J.1
Gabrielson, E.2
Werb, Z.3
Ewald, A.J.4
-
67
-
-
84862861973
-
Keratin 8 phosphorylation regulates keratin reorganization and migration of epithelial tumor cells
-
Busch T., Armacki M., Eiseler T., Joodi G., Temme C., Jansen J., von Wichert G., Omary M.B., Spatz J., Seufferlein T. Keratin 8 phosphorylation regulates keratin reorganization and migration of epithelial tumor cells. J Cell Sci 2012, 125:2148-2159.
-
(2012)
J Cell Sci
, vol.125
, pp. 2148-2159
-
-
Busch, T.1
Armacki, M.2
Eiseler, T.3
Joodi, G.4
Temme, C.5
Jansen, J.6
von Wichert, G.7
Omary, M.B.8
Spatz, J.9
Seufferlein, T.10
-
68
-
-
84882830710
-
Networking galore: intermediate filaments and cell migration
-
Chung B.M., Rotty J.D., Coulombe P.A. Networking galore: intermediate filaments and cell migration. Curr Opin Cell Biol 2013, 25:600-612.
-
(2013)
Curr Opin Cell Biol
, vol.25
, pp. 600-612
-
-
Chung, B.M.1
Rotty, J.D.2
Coulombe, P.A.3
-
69
-
-
84875726086
-
Effects of keratin phosphorylation on the mechanical properties of keratin filaments in living cells
-
Fois G., Weimer M., Busch T., Felder E.T., Oswald F., von Wichert G., Seufferlein T., Dietl P., Felder E. Effects of keratin phosphorylation on the mechanical properties of keratin filaments in living cells. FASEB J 2013, 27:1322-1329.
-
(2013)
FASEB J
, vol.27
, pp. 1322-1329
-
-
Fois, G.1
Weimer, M.2
Busch, T.3
Felder, E.T.4
Oswald, F.5
von Wichert, G.6
Seufferlein, T.7
Dietl, P.8
Felder, E.9
-
70
-
-
84885453808
-
A novel mechanism of keratin cytoskeleton organization through casein kinase Ialpha and FAM83H in colorectal cancer
-
Kuga T., Kume H., Kawasaki N., Sato M., Adachi J., Shiromizu T., Hoshino I., Nishimori T., Matsubara H., Tomonaga T. A novel mechanism of keratin cytoskeleton organization through casein kinase Ialpha and FAM83H in colorectal cancer. J Cell Sci 2013, 126:4721-4731.
-
(2013)
J Cell Sci
, vol.126
, pp. 4721-4731
-
-
Kuga, T.1
Kume, H.2
Kawasaki, N.3
Sato, M.4
Adachi, J.5
Shiromizu, T.6
Hoshino, I.7
Nishimori, T.8
Matsubara, H.9
Tomonaga, T.10
-
71
-
-
84874394209
-
Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation
-
Snider N.T., Leonard J.M., Kwan R., Griggs N.W., Rui L., Omary M.B. Glucose and SIRT2 reciprocally mediate the regulation of keratin 8 by lysine acetylation. J Cell Biol 2013, 200:241-247.
-
(2013)
J Cell Biol
, vol.200
, pp. 241-247
-
-
Snider, N.T.1
Leonard, J.M.2
Kwan, R.3
Griggs, N.W.4
Rui, L.5
Omary, M.B.6
-
72
-
-
84875546392
-
Keratin 8/18 regulation of glucose metabolism in normal versus cancerous hepatic cells through differential modulation of hexokinase status and insulin signaling
-
Mathew J., Loranger A., Gilbert S., Faure R., Marceau N. Keratin 8/18 regulation of glucose metabolism in normal versus cancerous hepatic cells through differential modulation of hexokinase status and insulin signaling. Exp Cell Res 2013, 319:474-486.
-
(2013)
Exp Cell Res
, vol.319
, pp. 474-486
-
-
Mathew, J.1
Loranger, A.2
Gilbert, S.3
Faure, R.4
Marceau, N.5
-
73
-
-
84890450731
-
Keratin 8 modulates beta-cell stress responses and normoglycaemia
-
Alam C.M., Silvander J.S., Daniel E.N., Tao G.Z., Kvarnstrom S.M., Alam P., Omary M.B., Hanninen A., Toivola D.M. Keratin 8 modulates beta-cell stress responses and normoglycaemia. J Cell Sci 2013, 126:5635-5644.
-
(2013)
J Cell Sci
, vol.126
, pp. 5635-5644
-
-
Alam, C.M.1
Silvander, J.S.2
Daniel, E.N.3
Tao, G.Z.4
Kvarnstrom, S.M.5
Alam, P.6
Omary, M.B.7
Hanninen, A.8
Toivola, D.M.9
-
74
-
-
84897417177
-
Mutation of caspase-digestion sites in keratin 18 interferes with filament reorganization, and predisposes to hepatocyte necrosis and loss of membrane integrity
-
Weerasinghe S.V., Ku N.O., Altshuler P.J., Kwan R., Omary M.B. Mutation of caspase-digestion sites in keratin 18 interferes with filament reorganization, and predisposes to hepatocyte necrosis and loss of membrane integrity. J Cell Sci 2014, 127:1464-1475.
-
(2014)
J Cell Sci
, vol.127
, pp. 1464-1475
-
-
Weerasinghe, S.V.1
Ku, N.O.2
Altshuler, P.J.3
Kwan, R.4
Omary, M.B.5
-
75
-
-
84856096159
-
Disruption of cytokeratin-8 interaction with F508del-CFTR corrects its functional defect
-
Colas J., Faure G., Saussereau E., Trudel S., Rabeh W.M., Bitam S., Guerrera I.C., Fritsch J., Sermet-Gaudelus I., Davezac N., et al. Disruption of cytokeratin-8 interaction with F508del-CFTR corrects its functional defect. Hum Mol Genet 2012, 21:623-634.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 623-634
-
-
Colas, J.1
Faure, G.2
Saussereau, E.3
Trudel, S.4
Rabeh, W.M.5
Bitam, S.6
Guerrera, I.C.7
Fritsch, J.8
Sermet-Gaudelus, I.9
Davezac, N.10
-
76
-
-
84861184577
-
Generic and personalized RNAi-based therapeutics for a dominant-negative epidermal fragility disorder
-
Pedrioli D.M.L., Fu D.J., Gonzalez-Gonzalez E., Contag C.H., Kaspar R.L., Smith F.J.D., McLean W.H.I. Generic and personalized RNAi-based therapeutics for a dominant-negative epidermal fragility disorder. J Invest Dermatol 2012, 132:1627-1635.
-
(2012)
J Invest Dermatol
, vol.132
, pp. 1627-1635
-
-
Pedrioli, D.M.L.1
Fu, D.J.2
Gonzalez-Gonzalez, E.3
Contag, C.H.4
Kaspar, R.L.5
Smith, F.J.D.6
McLean, W.H.I.7
-
77
-
-
84884536461
-
Keratin 8 is required for the maintenance of architectural structure in thymus epithelium
-
Odaka C., Loranger A., Takizawa K., Ouellet M., Tremblay M.J., Murata S., Inoko A., Inagaki M., Marceau N. Keratin 8 is required for the maintenance of architectural structure in thymus epithelium. PLOS ONE 2013, 8:e75101.
-
(2013)
PLOS ONE
, vol.8
, pp. e75101
-
-
Odaka, C.1
Loranger, A.2
Takizawa, K.3
Ouellet, M.4
Tremblay, M.J.5
Murata, S.6
Inoko, A.7
Inagaki, M.8
Marceau, N.9
-
78
-
-
84920971108
-
Regulation of keratin network organization
-
Loschke F., Seltmann K., Bouameur J.-E., Magin T.M. Regulation of keratin network organization. Curr Opin Cell Biol 2015, 32:56-64.
-
(2015)
Curr Opin Cell Biol
, vol.32
, pp. 56-64
-
-
Loschke, F.1
Seltmann, K.2
Bouameur, J.-E.3
Magin, T.M.4
|