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Volumn 60, Issue 1, 2014, Pages 167-174

Limited value of plasma cytokeratin-18 as a biomarker for NASH and fibrosis in patients with non-alcoholic fatty liver disease

Author keywords

Cytokeratin 18; Diabetes; Fatty liver; Insulin resistance; NAFLD; NASH

Indexed keywords

CYTOKERATIN 18;

EID: 84890547086     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.07.042     Document Type: Article
Times cited : (218)

References (33)
  • 1
    • 84864081494 scopus 로고    scopus 로고
    • Features, diagnosis, and treatment of non-alcoholic fatty liver disease
    • D.M. Torres, C.D. Williams, and S.A. Harrison Features, diagnosis, and treatment of non-alcoholic fatty liver disease Clin Gastroenterol Hepatol 10 2012 837 858
    • (2012) Clin Gastroenterol Hepatol , vol.10 , pp. 837-858
    • Torres, D.M.1    Williams, C.D.2    Harrison, S.A.3
  • 2
    • 84859404868 scopus 로고    scopus 로고
    • Role of obesity and lipotoxicity in the development of non-alcoholic steatohepatitis: Pathophysiology and clinical implications
    • K. Cusi Role of obesity and lipotoxicity in the development of non-alcoholic steatohepatitis: pathophysiology and clinical implications Gastroenterology 142 2012 711 725
    • (2012) Gastroenterology , vol.142 , pp. 711-725
    • Cusi, K.1
  • 3
    • 84861543083 scopus 로고    scopus 로고
    • The diagnosis and management of non-alcoholic fatty liver disease: Practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association
    • N. Chalasani, Z. Younossi, J.E. Lavine, A.M. Diehl, E.M. Brunt, and K. Cusi The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological Association Hepatology 55 2012 2005 2023
    • (2012) Hepatology , vol.55 , pp. 2005-2023
    • Chalasani, N.1    Younossi, Z.2    Lavine, J.E.3    Diehl, A.M.4    Brunt, E.M.5    Cusi, K.6
  • 4
    • 84859393575 scopus 로고    scopus 로고
    • Prevalence of prediabetes and diabetes and metabolic profile of patients with non-alcoholic fatty liver disease (NAFLD)
    • C. Ortiz-Lopez, R. Lomonaco, B. Orsak, J. Finch, Z. Chang, and V.G. Kochunov Prevalence of prediabetes and diabetes and metabolic profile of patients with non-alcoholic fatty liver disease (NAFLD) Diabetes Care 35 2012 873 878
    • (2012) Diabetes Care , vol.35 , pp. 873-878
    • Ortiz-Lopez, C.1    Lomonaco, R.2    Orsak, B.3    Finch, J.4    Chang, Z.5    Kochunov, V.G.6
  • 5
    • 78650486196 scopus 로고    scopus 로고
    • Prevalence of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: A prospective study
    • C.D. Williams, J. Stengel, M.I. Asike, D.M. Torres, J. Shaw, and M. Contreras Prevalence of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: a prospective study Gastroenterology 140 2011 124 131
    • (2011) Gastroenterology , vol.140 , pp. 124-131
    • Williams, C.D.1    Stengel, J.2    Asike, M.I.3    Torres, D.M.4    Shaw, J.5    Contreras, M.6
  • 6
    • 10644220306 scopus 로고    scopus 로고
    • Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity
    • J.D. Browning, L.S. Szczepaniak, R. Dobbins, P. Nuremberg, J.D. Horton, and J.C. Cohen Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity Hepatology 40 2004 1387 1395
    • (2004) Hepatology , vol.40 , pp. 1387-1395
    • Browning, J.D.1    Szczepaniak, L.S.2    Dobbins, R.3    Nuremberg, P.4    Horton, J.D.5    Cohen, J.C.6
  • 7
    • 52649112178 scopus 로고    scopus 로고
    • Development and validation of a simple NAFLD clinical scoring system for identifying patients without advanced disease
    • S. Harrison, D. Oliver, H. Arnold, S. Gogia, and B. Neuschwander-Tetri Development and validation of a simple NAFLD clinical scoring system for identifying patients without advanced disease Gut 57 2008 1441 1447
    • (2008) Gut , vol.57 , pp. 1441-1447
    • Harrison, S.1    Oliver, D.2    Arnold, H.3    Gogia, S.4    Neuschwander-Tetri, B.5
  • 8
    • 80555136061 scopus 로고    scopus 로고
    • Meta-analysis: Natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity
    • G. Musso, R. Gambino, M. Cassader, and G. Pagano Meta-analysis: Natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity Ann Med 43 2011 617 649
    • (2011) Ann Med , vol.43 , pp. 617-649
    • Musso, G.1    Gambino, R.2    Cassader, M.3    Pagano, G.4
  • 9
    • 79251535913 scopus 로고    scopus 로고
    • Non-invasive diagnosis of non-alcoholic fatty liver and non-alcoholic steatohepatitis
    • L.A. Adams, and A.E. Feldstein Non-invasive diagnosis of non-alcoholic fatty liver and non-alcoholic steatohepatitis J Dig Dis 12 2011 10 16
    • (2011) J Dig Dis , vol.12 , pp. 10-16
    • Adams, L.A.1    Feldstein, A.E.2
  • 10
    • 84856755822 scopus 로고    scopus 로고
    • The association between adipocytokines and biomarkers for non-alcoholic fatty liver disease-induced liver injury: A study in the general population
    • S. Zelber-Sagi, V. Ratziu, I. Zvibel, I. Goldiner, L. Blendis, and G. Morali The association between adipocytokines and biomarkers for non-alcoholic fatty liver disease-induced liver injury: a study in the general population Eur J Gastroenterol Hepatol 24 2012 262 269
    • (2012) Eur J Gastroenterol Hepatol , vol.24 , pp. 262-269
    • Zelber-Sagi, S.1    Ratziu, V.2    Zvibel, I.3    Goldiner, I.4    Blendis, L.5    Morali, G.6
  • 12
    • 79952457093 scopus 로고    scopus 로고
    • Systematic review of performance of non-invasive biomarkers in the evaluation of non-alcoholic fatty liver disease
    • M.H. Miller, M.A. Ferguson, and J.F. Dillon Systematic review of performance of non-invasive biomarkers in the evaluation of non-alcoholic fatty liver disease Liver Int 31 2011 461 473
    • (2011) Liver Int , vol.31 , pp. 461-473
    • Miller, M.H.1    Ferguson, M.A.2    Dillon, J.F.3
  • 13
    • 70350046669 scopus 로고    scopus 로고
    • Cytokeratin-18 fragment levels as noninvasive biomarkers for non-alcoholic steatohepatitis: A multicenter validation study
    • A.E. Feldstein, A. Wieckowska, A.R. Lopez, Y.C. Liu, N.N. Zein, and A.J. McCullough Cytokeratin-18 fragment levels as noninvasive biomarkers for non-alcoholic steatohepatitis: a multicenter validation study Hepatology 50 2009 1072 1078
    • (2009) Hepatology , vol.50 , pp. 1072-1078
    • Feldstein, A.E.1    Wieckowska, A.2    Lopez, A.R.3    Liu, Y.C.4    Zein, N.N.5    McCullough, A.J.6
  • 14
    • 72049105082 scopus 로고    scopus 로고
    • Cytokeratin-18 fragments and biomarkers of the metabolic syndrome in non-alcoholic steatohepatitis
    • Y. Yilmaz, A.E. Kedrah, and O. Ozdogan Cytokeratin-18 fragments and biomarkers of the metabolic syndrome in non-alcoholic steatohepatitis World J Gastroenterol 15 2009 4387 4391
    • (2009) World J Gastroenterol , vol.15 , pp. 4387-4391
    • Yilmaz, Y.1    Kedrah, A.E.2    Ozdogan, O.3
  • 15
    • 84862795311 scopus 로고    scopus 로고
    • Non-invasive diagnosis of non-alcoholic steatohepatitis by combined serum biomarkers
    • J. Shen, H.L. Chan, G.L. Wong, P.C. Choi, A.W. Chan, and H.Y. Chan Non-invasive diagnosis of non-alcoholic steatohepatitis by combined serum biomarkers J Hepatol 56 2012 1363 1370
    • (2012) J Hepatol , vol.56 , pp. 1363-1370
    • Shen, J.1    Chan, H.L.2    Wong, G.L.3    Choi, P.C.4    Chan, A.W.5    Chan, H.Y.6
  • 16
    • 33751545838 scopus 로고    scopus 로고
    • A placebo-controlled trial of pioglitazone in subjects with non-alcoholic steatohepatitis
    • R. Belfort, S.A. Harrison, K. Brown, C. Darland, J. Finch, and J. Hardies A placebo-controlled trial of pioglitazone in subjects with non-alcoholic steatohepatitis N Engl J Med 355 2006 2297 2307
    • (2006) N Engl J Med , vol.355 , pp. 2297-2307
    • Belfort, R.1    Harrison, S.A.2    Brown, K.3    Darland, C.4    Finch, J.5    Hardies, J.6
  • 17
    • 80052032690 scopus 로고    scopus 로고
    • Role of ethnicity in overweight and obese patients with non-alcoholic steatohepatitis
    • R. Lomonaco, C. Ortiz-Lopez, B. Orsak, J. Finch, A. Webb, and F. Bril Role of ethnicity in overweight and obese patients with non-alcoholic steatohepatitis Hepatology 54 2011 837 845
    • (2011) Hepatology , vol.54 , pp. 837-845
    • Lomonaco, R.1    Ortiz-Lopez, C.2    Orsak, B.3    Finch, J.4    Webb, A.5    Bril, F.6
  • 18
    • 84859942552 scopus 로고    scopus 로고
    • Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with non-alcoholic fatty liver disease
    • R. Lomonaco, C. Ortiz-Lopez, B. Orsak, A. Webb, J. Hardies, and C. Darland Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with non-alcoholic fatty liver disease Hepatology 55 2012 1389 1397
    • (2012) Hepatology , vol.55 , pp. 1389-1397
    • Lomonaco, R.1    Ortiz-Lopez, C.2    Orsak, B.3    Webb, A.4    Hardies, J.5    Darland, C.6
  • 19
    • 0029819936 scopus 로고    scopus 로고
    • Metabolic effects of metformin on glucose and lactate metabolism in NIDDM
    • K. Cusi, A. Consoli, and R. DeFronzo Metabolic effects of metformin on glucose and lactate metabolism in NIDDM J Clin Endo Metab 81 1996 4059 4067
    • (1996) J Clin Endo Metab , vol.81 , pp. 4059-4067
    • Cusi, K.1    Consoli, A.2    Defronzo, R.3
  • 20
    • 0033968126 scopus 로고    scopus 로고
    • Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle
    • K. Cusi, K. Maezono, A. Osman, M. Pendergrass, M. Patti, and T. Pranawatapatr Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle J Clin Invest 105 2000 311 320
    • (2000) J Clin Invest , vol.105 , pp. 311-320
    • Cusi, K.1    Maezono, K.2    Osman, A.3    Pendergrass, M.4    Patti, M.5    Pranawatapatr, T.6
  • 21
    • 76149092815 scopus 로고    scopus 로고
    • Fenofibrate reduces systemic inflammation markers independent of its effects on lipid and glucose metabolism in patients with the metabolic syndrome
    • R. Belfort, R. Berria, J. Cornell, and K. Cusi Fenofibrate reduces systemic inflammation markers independent of its effects on lipid and glucose metabolism in patients with the metabolic syndrome J Clin Endocrinol Metab 95 2010 829 836
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 829-836
    • Belfort, R.1    Berria, R.2    Cornell, J.3    Cusi, K.4
  • 22
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for non-alcoholic fatty liver disease
    • D.E. Kleiner, E.M. Brunt, M. Van Natta, C. Behling, M.J. Contos, and O.W. Cummings Design and validation of a histological scoring system for non-alcoholic fatty liver disease Hepatology 41 2005 1313 1321
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van Natta, M.3    Behling, C.4    Contos, M.J.5    Cummings, O.W.6
  • 24
    • 55149102644 scopus 로고    scopus 로고
    • Cytokeratin 18 fragment levels as a noninvasive biomarker for non-alcoholic steatohepatitis in bariatric surgery patients
    • D.L. Diab, L. Yerian, P. Schauer, S.R. Kashyap, R. Lopez, and S.L. Hazen Cytokeratin 18 fragment levels as a noninvasive biomarker for non-alcoholic steatohepatitis in bariatric surgery patients Clin Gastroenterol Hepatol 6 2008 1249 1254
    • (2008) Clin Gastroenterol Hepatol , vol.6 , pp. 1249-1254
    • Diab, D.L.1    Yerian, L.2    Schauer, P.3    Kashyap, S.R.4    Lopez, R.5    Hazen, S.L.6
  • 25
    • 53849114643 scopus 로고    scopus 로고
    • A novel diagnostic biomarker panel for obesity-related non-alcoholic steatohepatitis (NASH)
    • Z.M. Younossi, M. Jarrar, C. Nugent, M. Randhawa, M. Afendy, and M. Stepanova A novel diagnostic biomarker panel for obesity-related non-alcoholic steatohepatitis (NASH) Obes Surg 18 2008 1430 1437
    • (2008) Obes Surg , vol.18 , pp. 1430-1437
    • Younossi, Z.M.1    Jarrar, M.2    Nugent, C.3    Randhawa, M.4    Afendy, M.5    Stepanova, M.6
  • 27
    • 84856388968 scopus 로고    scopus 로고
    • Prospective biopsy-controlled evaluation of cell death biomarkers for prediction of liver fibrosis and non-alcoholic steatohepatitis
    • D. Joka, K. Wahl, S. Moeller, J. Schlue, B. Vaske, and M.J. Bahr Prospective biopsy-controlled evaluation of cell death biomarkers for prediction of liver fibrosis and non-alcoholic steatohepatitis Hepatology 55 2012 455 464
    • (2012) Hepatology , vol.55 , pp. 455-464
    • Joka, D.1    Wahl, K.2    Moeller, S.3    Schlue, J.4    Vaske, B.5    Bahr, M.J.6
  • 28
    • 84855554342 scopus 로고    scopus 로고
    • Growth hormone, dehydroepiandrosterone and adiponectin levels in non-alcoholic steatohepatitis: An endocrine signature for advanced fibrosis in obese patients
    • E. Koehler, J. Swain, S. Sanderson, A. Krishnan, K. Watt, and M. Charlton Growth hormone, dehydroepiandrosterone and adiponectin levels in non-alcoholic steatohepatitis: an endocrine signature for advanced fibrosis in obese patients Liver Int 32 2012 279 286
    • (2012) Liver Int , vol.32 , pp. 279-286
    • Koehler, E.1    Swain, J.2    Sanderson, S.3    Krishnan, A.4    Watt, K.5    Charlton, M.6
  • 29
    • 34547514221 scopus 로고    scopus 로고
    • Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects
    • A. Gastaldelli, K. Cusi, M. Pettiti, J. Hardies, Y. Miyazaki, and R. Berria Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects Gastroenterology 133 2007 496 506
    • (2007) Gastroenterology , vol.133 , pp. 496-506
    • Gastaldelli, A.1    Cusi, K.2    Pettiti, M.3    Hardies, J.4    Miyazaki, Y.5    Berria, R.6
  • 32
    • 84867165316 scopus 로고    scopus 로고
    • Pentoxifylline decreases oxidized lipid products in non-alcoholic steatohepatitis: New evidence on the potential therapeutic mechanism
    • C.O. Zein, R. Lopez, X. Fu, J.P. Kirwan, L.M. Yerian, and A.J. McCullough Pentoxifylline decreases oxidized lipid products in non-alcoholic steatohepatitis: new evidence on the potential therapeutic mechanism Hepatology 56 2012 1291 1299
    • (2012) Hepatology , vol.56 , pp. 1291-1299
    • Zein, C.O.1    Lopez, R.2    Fu, X.3    Kirwan, J.P.4    Yerian, L.M.5    McCullough, A.J.6
  • 33
    • 77956822767 scopus 로고    scopus 로고
    • Mass spectrometric profiling of oxidized lipid products in human non-alcoholic fatty liver disease and non-alcoholic steatohepatitis
    • A.E. Feldstein, R. Lopez, T.A. Tamimi, L. Yerian, Y.M. Chung, and M. Berk Mass spectrometric profiling of oxidized lipid products in human non-alcoholic fatty liver disease and non-alcoholic steatohepatitis J Lipid Res 51 2010 3046 3054
    • (2010) J Lipid Res , vol.51 , pp. 3046-3054
    • Feldstein, A.E.1    Lopez, R.2    Tamimi, T.A.3    Yerian, L.4    Chung, Y.M.5    Berk, M.6


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