Parenteral nutrition decreases paneth cell function and intestinal bactericidal activity while increasing susceptibility to bacterial enteroinvasion

Journal of Parenteral and Enteral Nutrition

Volumn 38, Issue 7, 2014, Pages 817-824

  Heneghan, Aaron F ^a,b   Pierre, Joseph F ^a,b   Tandee, Kanokwan ^c   Shanmuganayagam, Dhanansayan ^c   Wang, Xinying ^b   Reed, Jess D ^c   Steele, James L ^c   Kudsk, Kenneth A ^a,b  

^a WILLIAM S MIDDLETON MEMORIAL VETERANS HOSPITAL   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

innate immunity, cryptdins, microbiome; Paneth cells; parenteral nutrition; small intestine

Indexed keywords

BETA ACTIN; LYSOZYME; RNA 16S; ALPHA DEFENSIN; CRYPTDIN 4, MOUSE; PROTEIN; REG3G PROTEIN, MOUSE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; BACTERICIDAL ACTIVITY; BACTEROIDETES; CELL FUNCTION; CELLULAR SECRETION; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENTERIC FEEDING; ESCHERICHIA COLI; EX VIVO STUDY; FIRMICUTES; GASTROINTESTINAL INFECTION; ILEUM; INFECTION RISK; INNATE IMMUNITY; MALE; MICROBIOME; MOUSE; NONHUMAN; PANETH CELL; PARENTERAL NUTRITION; PRIORITY JOURNAL; PROTEOBACTERIA; PYROSEQUENCING; ADVERSE EFFECTS; ANIMAL; BACTERIA; CYTOLOGY; GROWTH, DEVELOPMENT AND AGING; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; MICROBIOLOGY; MICROFLORA; MUCOSAL IMMUNITY;

BACTERIA (MICROORGANISMS); BACTEROIDETES; FIRMICUTES; MUS; PROTEOBACTERIA;

ALPHA-DEFENSINS; ANIMALS; BACTERIA; DISEASE SUSCEPTIBILITY; ESCHERICHIA COLI; ILEUM; IMMUNITY, MUCOSAL; MALE; MICE, INBRED ICR; MICROBIOTA; MURAMIDASE; PANETH CELLS; PARENTERAL NUTRITION; PROTEINS;

EID: 84921054422     PISSN: 01486071     EISSN: 19412444     Source Type: Journal    
DOI: 10.1177/0148607113497514     Document Type: Article

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