TPN decreases IL-4 and IL-10 mRNA expression in lipopolysaccharide stimulated intestinal lamina propria cells but glutamine supplementation preserves the expression

Shock

Volumn 15, Issue 4, 2001, Pages 318-322

  Fukatsu, Kazuhiko ^a   Kudsk, Kenneth A ^a,b   Zarzaur, Ben L ^a   Wu, Yong ^a   Hanna, M Keith ^a   DeWitt, R Chance ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b NONE   (United States)

Author keywords

Cytokines; Enteral feeding; Glutamine; Gut associated lymphoid tissue (GALT); IgA; Mucosal immunity; Parenteral feeding

Indexed keywords

CYTOKINE; GLUTAMINE; IMMUNOGLOBULIN A; INTERLEUKIN 10; INTERLEUKIN 4; LIPOPOLYSACCHARIDE; MESSENGER RNA;

ANIMAL; ANIMAL FOOD; ARTICLE; BIOSYNTHESIS; COMPARATIVE STUDY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; GASTROSTOMY; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; INTESTINE MUCOSA; LAPAROTOMY; LYMPHOID TISSUE; MALE; METABOLISM; MOUSE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMALL INTESTINE; TOTAL PARENTERAL NUTRITION; WEIGHT REDUCTION;

ANIMAL FEED; ANIMALS; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; GASTROSTOMY; GENE EXPRESSION REGULATION; GLUTAMINE; IMMUNOGLOBULIN A; INTERLEUKIN-10; INTERLEUKIN-4; INTESTINAL MUCOSA; INTESTINE, SMALL; LAPAROTOMY; LIPOPOLYSACCHARIDES; LYMPHOID TISSUE; MALE; MICE; MICE, INBRED ICR; PARENTERAL NUTRITION, TOTAL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; WEIGHT LOSS;

EID: 0035316623     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-200115040-00012     Document Type: Article

References (26)

1. Moore FA, Feliciano DV, Andrassy RJ, McArdle AH, Booth FV McL, Morgenstein-Wagner TB, Kellum JM, Welling RE, Moore EE: Early enterai feeding, compared with parenteral, reduces postoperative septic complications: the results of a meta-analysis. Ann Surg 216:172-183, 1992.
2. Kudsk KA, Croce MA, Fabian TC, Minard G, Tolley EA, Poret HA, Kuhl MR, Brown RO: Enteral versus parenteral feeding: effects on septic morbidity after blunt and penetrating abdominal trauma. Ann Surg 215:503-513, 1991.
3. Moore EE, Jones TN: Benefits of immediate jejunostomy feeding after major abdominal trauma - a prospective, randomized study. J Trauma 26:874-880, 1986
4. Moore FA, Moore EE, Jones TN, McCroskey BL, Peterson VM: TEN versus PN following major abdominal trauma - reduced septic morbidity. J Trauma 29:916-922, 1989.
5. Li J, Kudsk KA, Gocinski B, Dent D, Glezer J, Langkamp-Henken B: Effects of parenteral and enteral nutrition on gut-associated lymphoid tissue. J Trauma 39:44-52, 1995.
6. Kudsk KA, Li J, Renegar KB: Loss of upper respiratory tract immunity with parenteral feeding. Ann Surg 223:629-638, 1996.
7. Ziegler TR, Young LS, Benfell K, Scheltinga M, Hortos K, Bye R, Morrow FD, Jacobs DO, Smith RJ, Antin JH, et al: Clinical and metabolic efficacy of glutamine-supplemented parenteral nutrition after bone marrow transplantation. A randomized, double-blind, controlled study. Ann Intern Med 116:821-828, 1992.
8. Li J, Kudsk KA, Janu PG, Renegar KB: Effect of glutamine-enriched total parenteral nutrition on small intestinal gut-associated lymphoid tissue and upper respiratory tract immunity. Surgery 121:542-549, 1997.
9. DeWitt RC, Wu Y, Renegar KB, Kudsk KA: Glutamine-enriched total parenteral nutrition preserves respiratory immunity and improves survival to a Pseudomonas pneumonia. J Surg Res 84:13-18, 1999.
10. Kudsk KA, Wu Y, Fukatsu K, Zarzaur BL, Johnson CD, Wang R, Hanna MK. Glutamine-enriched TPN maintains intestinal IL-4 and mucosal IgA levels. J Parenter Enterai Nutr 24:270-275, 2000.
11. Kramer DR, Sutherland RM, Bao S, Husband AJ: Cytokine-mediated effects in mucosal immunity. Immunol Cell Biol 73:389-396, 1995.
12. Ramsay A: Genetic approaches to the study of cytokine regulation of mucosal immunity. Immunol Cell Biol 73:484-488, 1995.
13. Lebman DA, Coffman RL: Cytokines in the mucosal immune system. In Ogra PL, Lamm ME, McGhee Jr, Mestecky J, Strober W, Bienenstock J (eds): Handbook of Mucosal Immunology. San Diego, CA: Academic Press, 1994, pp 243-249.
14. Wu Y, Kudsk KA, DeWitt RC, Tolley EA, Li J: Route and type of nutrition influence IgA-mediating intestinal cytokines. Ann Surg 229:662-667, 1999.
15. Sitren HS, Heller PA, Bailey LB, Cerda JJ: Total parenteral nutrition in the mouse: development of a technique. J Parenter Enteral Nutr 7:582-586, 1983.
16. Salmi M, Jalkanen S: Regulation of lymphocyte traffic to mucosa-associated lymphatic tissues. Gastroenterol Clin North Am 20:495-510, 1991.
17. Phillips-Quagliata JM, Lamm ME: Lymphocyte homing to mucosal effector sites. In Ogra PL, Lamm ME, McGhee Jr, Mestecky J, Strober W, Bienenstock J (eds): Handbook of Mucosal Immunology. San Diego: Academic Press, 1994, pp 225-239.
18. Renegar KB, Kudsk KA, DeWitt RC, Wu Y, King BK. Impairment of mucosal immunity by parenteral nutrition: Depressed nasotracheal influenza-specific secretory IgA levels and transport of parenterally fed mice. Ann Surg, in press.
19. Newsholme EA, Crabtree B, Ardawi MSM: The role of high rates of glycolysis and glutamine utilization in rapidly dividing cells. Biosci Res 5:393-400, 1985.
20. Windmueller HG, Spaeth AE: Respiratory fuels and nitrogen metabolism in vivo in small intestine of fed rats. J Biol Chem 255:107-112, 1980.
21. Evers MB, Bold RJ, Ehrenfried JA, Li J, Townsend CM, Klimpel GR: Characterization of functional neurotensin receptors on human lymphocytes. Surgery 116:134-140, 1994.
22. Li J, Kudsk KA, Hamidian M, Gocinski BL: Bombesin affects mucosal immunity and gut-associated lymphoid tissue in intravenously fed mice. Arch Surg 130:1164-1170, 1995.
23. Streeter PR, Berg EL, Rouse BT, Bargatze RF, Butcher EC: A tissue-specific endothelial cell molecule involved in lymphocyte homing. Nature 331:41-46, 1988.
24. Briskin M, Winsor-Hines D, Shyjan A, Cochran N, Bloom S, Wilson J, McEvoy LM, Butcher EC, Kassam N, Mackay CR, Newman W: Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue. Am J Pathol 151:97-110, 1997.
25. Austrup F, Vestweber D, Borges E, Lohning M, Brauer R, Herz U, Renz H, Hallmann R, Scheffold A, radbruch A, Hamann A: P-and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues. Nature 385:81-83, 1997.
26. Fukatsu K, Lundberg AH, Hanna MK, Wu Y, Wilcox HG, Granger DN, Gaber AO, Kudsk KA: Increased expression of intestinal P-selectin and pulmonary E-selectin during IV-TPN. Arch Surg 135:1177-1182, 2000.