Hematopoietic IKBKE limits the chronicity of inflammasome priming and metaflammation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 2, 2015, Pages 506-511

  Patel, Meghana N ^a   Bernard, William G ^a,b   Milev, Nikolay B ^a   Cawthorn, William P ^a   Figg, Nichola ^b   Hart, Dan ^a   Prieur, Xavier ^a   Virtue, Sam ^a   Hegyi, Krisztina ^a   Bonnafous, Stephanie ^c,d,e   Bailly Maitre, Beatrice ^c,d,e   Chuf, Yajing ^a,f   Griffinf, Julian L ^a,f   Mallat, Ziad ^b   Considineh, Robert V ^g   Tranc, Albert ^c,d,e   Gual, Philippe ^c,d,e   Takeuchi, Osamu ^h   Akira, Shizuo ^h   Vidal Pui, Antonio ^a   Bennett, Martin R ^b   Sethi, Jaswinder K ^a   more..

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b CAMBRIDGE UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

^c INSERM   (France)

^d Digestive Center   (France)

^e UNIVERSITÉ CÔTE D'AZUR   (France)

^f MRC HUMAN NUTRITION RESEARCH   (United Kingdom)

^g INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h OSAKA UNIVERSITY   (Japan)

Author keywords

IKBKE; Immunometabolism; Inflammasome; Metabolic disease; Metaflammation

Indexed keywords

GAMMA INTERFERON; I KAPPA B KINASE EPSILON; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 4; PEPTIDOGLYCAN; APOLIPOPROTEIN E; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; I KAPPA B KINASE; IKBKE PROTEIN, HUMAN; IKBKE PROTEIN, MOUSE; MESSENGER RNA;

ACUTE PHASE RESPONSE; ADIPOSE TISSUE; ANIMAL EXPERIMENT; ARTICLE; ATHEROSCLEROSIS; CHRONIC INFLAMMATION; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE EXPRESSION PROFILING; GENOTYPE; HEMATOPOIETIC CELL; HUMAN; HUMAN TISSUE; HYPERCHOLESTEROLEMIA; MACROPHAGE; METABOLIC DISORDER; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; ADULT; ANIMAL; C57BL MOUSE; DEFICIENCY; GENETICS; HEMATOPOIETIC SYSTEM; INFLAMMATION; KNOCKOUT MOUSE; LIVER; MALE; METABOLIC SYNDROME X; METABOLISM; MOUSE MUTANT; PLAQUE, ATHEROSCLEROTIC;

MURINAE; MUS;

ADIPOSE TISSUE; ADULT; ANIMALS; APOLIPOPROTEINS E; CARRIER PROTEINS; FEMALE; HEMATOPOIETIC SYSTEM; HUMANS; I-KAPPA B KINASE; INFLAMMASOMES; INFLAMMATION; LIVER; MACROPHAGES; MALE; METABOLIC SYNDROME X; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, OBESE; PLAQUE, ATHEROSCLEROTIC; RNA, MESSENGER;

EID: 84920997067     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1414536112     Document Type: Article

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