The histone demethylase Fbxl11/Kdm2a plays an essential role in embryonic development by repressing cell-cycle regulators

Mechanisms of Development

Volumn 135, Issue , 2015, Pages 31-42

  Kawakami, Eri ^a,b   Tokunaga, Akinori ^a,b   Ozawa, Manabu ^a   Sakamoto, Reiko ^a   Yoshida, Nobuaki ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b OITA UNIVERSITY   (Japan)

Author keywords

Embryogenesis; Fbxl11; Histone demethylase; Kdm2a; P21

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1; F BOX AND LEUCINE RICH REPEAT 11 PROTEIN; HISTONE DEMETHYLASE; HISTONE H2A; TRANSCRIPTION FACTOR EZH2; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; FBXL11 PROTEIN, MOUSE; HISTONE; POLYCOMB GROUP PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; EMBRYO DEATH; EMBRYO DEVELOPMENT; GENE REPRESSION; GROWTH RETARDATION; HISTONE UBIQUITINATION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; UPREGULATION; ANIMAL; ANIMAL EMBRYO; C57BL MOUSE; CELL LINE; CELL SURVIVAL; CYTOLOGY; ENZYMOLOGY; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; LETHAL GENE; MALE; METABOLISM; PHYSIOLOGY; PROTEIN PROCESSING;

MAMMALIA; MUS;

ANIMALS; CELL CYCLE PROTEINS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, LETHAL; HISTONES; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; POLYCOMB-GROUP PROTEINS; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 84920911188     PISSN: 09254773     EISSN: 18726356     Source Type: Journal    
DOI: 10.1016/j.mod.2014.10.001     Document Type: Article

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