Depletion of histone demethylase KDM2A inhibited cell proliferation of stem cells from apical papilla by de-repression of p15INK4B and p27 Kip1

Molecular and Cellular Biochemistry

Volumn 379, Issue 1-2, 2013, Pages 115-122

  Gao, Runtao ^a   Dong, Rui ^b   Du, Juan ^b   Ma, Ping ^b   Wang, Songlin ^b   Fan, Zhipeng ^b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Cell proliferation; KDM2A; p15 INK4B; p27Kip1; Stem cells from apical papilla

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN DEPENDENT KINASE INHIBITOR 2B; HISTONE DEMETHYLASE; SHORT HAIRPIN RNA;

ARTICLE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; G1 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; HUMAN TISSUE; PROTEIN DEPLETION; PROTEIN EXPRESSION; STEM CELL; STEM CELL FROM APICAL PAPILLA;

CELL PROLIFERATION; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P15; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DENTAL PAPILLA; DNA METHYLATION; F-BOX PROTEINS; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HISTONES; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; PROMOTER REGIONS, GENETIC; RNA, SMALL INTERFERING; STEM CELLS;

MAMMALIA;

EID: 84878458649     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1633-7     Document Type: Article

References (32)

1. Jahagirdar BN, Verfaillie CM (2005) Multipotent adult progenitor cell and stem cell plasticity. Stem Cell Rev 1:53-59
2. Phinney DG, Prockop DJ (2007) Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair - current views. Stem Cells 25:2896-2902
3. Scaffidi P, Misteli T (2008) Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing. Nat Cell Biol 10:452-459
4. Shi S, Gronthos S, Chen S et al (2002) Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression. Nat Biotechnol 20:587-591
5. Shi S, Wang CY (2004) Bone marrow stromal stem cells for repairing the skeleton. Biotechnol Genet Eng Rev 21:133-143
6. Sonoyama W, Liu Y, Fang D et al (2006) Mesenchymal stem cell-mediated functional tooth regeneration in swine. PLoS ONE 1:e79
7. Seo BM, Miura M, Gronthos S et al (2004) Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet 364:149-155
8. Arthur A, Rychkov G, Shi S et al (2008) Adult human dental pulp stem cells differentiate towards functionally active neurons under appropriate environmental cues. Stem Cells 26:1787-1795
9. Gronthos S, Mankani M, Brahim J et al (2000) Postnatal human Dental Pulp Stem Cells (DPSCs) in vitro and in vivo. Proc Natl Acad Sci USA 97:13625-13630
10. Miura M, Gronthos S, Zhao M et al (2003) SHED: stem cells from human exfoliated deciduous teeth. Proc Natl Acad Sci USA 100:5807-5812
11. Iwata T, Yamato M, Zhang Z et al (2010) Validation of human periodontal ligament-derived cells as a reliable source for cytotherapeutic use. J Clin Periodontol 37:1088-1099
12. Chang J, Sonoyama W, Wang Z et al (2007) Noncanonical Wnt4 signaling enhances bone regeneration of mesenchymal stem cells in craniofacial defects through activation of p38 MAPK. J Biol Chem 282:30938-30948
13. Liu Y, Zheng Y, Ding G et al (2008) Periodontal ligament stem cell-mediated treatment for periodontitis in miniatureswine. Stem Cells 26:1065-1073
14. Ding G, Liu Y, Wang W et al (2010) Allogeneic periodontal ligament stem cell therapy for periodontitis in swine. Stem Cells 28:1829-1838
15. Cenciarelli C, Chiaur DS, Guardavaccaro D et al (1999) Identification of a family of human F-box proteins. Curr Biol 9:1177-1179
16. Winston JT, Koepp DM, Zhu C et al (1999) A family of mammalian F-box proteins. Curr Biol 9:1180-1182
17. Clissold PM, Ponting CP (2001) JmjC: Cupin metalloenzyme-like domains in jumonji, hairless and phospholipase A2beta. Trends Biochem Sci 26:7-9
18. Tsukada Y, Fang J, Erdjument-Bromage H et al (2006) Histone demethylation by a family of JmjC domain-containing proteins. Nature 439:811-816
19. Du J, Ma Y, Ma P et al (2013) Demethylation of epiregulin gene by histone demethylase FBXL11 and BCL6 corepressor inhibits osteo/dentinogenic differentiation. Stem Cells 31:126-136
20. Fan Z, Yamaza T, Lee JS et al (2009) BCOR regulates mesenchymal stem cell function by epigenetic mechanisms. Nat Cell Biol 11:1002-1009
21. He J, Kallin EM, Tsukada Y et al (2008) The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15(Ink4b). Nat Struct Mol Biol 15:1169-1175
22. Pfau R, Tzatsos A, Kampranis SC et al (2008) Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process. Proc Natl Acad Sci USA 105:1907-1912
23. Lu T, Jackson MW, Singhi AD et al (2009) Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB. Proc Natl Acad Sci USA 106:16339-16344
24. Cuesta R, Martínez-Sánchez A, Gebauer F (2009) miR-181a regulates cap-dependent translation of p27(kip1) mRNA in myeloid cells. Mol Cell Biol 29:2841-2851
25. Sherr CJ, Roberts JM (1995) Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 9:1149-1163
26. Polyak K, Lee MH, Erdjument-Bromage H et al (1994) Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78:59-66
27. Thomas DM, Johnson SA, Sims NA et al (2004) Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma. J Cell Biol 167:925-934
28. Gil J, Peters G (2006) Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all. Nat Rev Mol Cell Biol 7:667-677
29. Ortega S, Malumbres M, Barbacid M (2002) Cyclin D-dependent kinases, INK4 inhibitors and cancer. Biochim Biophys Acta 1602:73-87
30. Li H, Collado M, Villasante A et al (2009) The Ink4/Arf locus is a barrier for iPS cell reprogramming. Nature 460:1136-1139
31. Miles RR, Crockett DK, Lim MS et al (2005) Analysis of BCL6-interacting proteins by tandem mass spectrometry. Mol Cell Proteomics 4:1898-1909
32. Gearhart MD, Corcoran CM, Wamstad JA et al (2006) Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets. Mol Cell Biol 26:6880-6889