Depletion of histone demethylase KDM2A enhanced the adipogenic and chondrogenic differentiation potentials of stem cells from apical papilla

Experimental Cell Research

Volumn 319, Issue 18, 2013, Pages 2874-2882

  Dong, Rui ^a   Yao, Rui ^b   Du, Juan ^a   Wang, Songlin ^a   Fan, Zhipeng ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b NANKAI UNIVERSITY   (China)

Author keywords

Adipogenic; Chondrogenic; Histone demethylase; KDM2A; Stem cells from apical papilla (SCAPs)

Indexed keywords

GLUCOSE TRANSPORTER 4; HISTONE DEMETHYLASE; HISTONE H3; HISTONE H3 LYSINE 4; LYSINE (K)SPECIFIC DEMETHYLASE 2A; MESSENGER RNA; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ADIPOGENESIS; ADOLESCENT; ADULT; ARTICLE; CELL DIFFERENTIATION; CHONDROGENESIS; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; GENE EXPRESSION; GENE LOCUS; HUMAN; HUMAN CELL; LENTIVIRUS INFECTION; MESENCHYMAL STEM CELL; MOLECULAR MECHANICS; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TOOTH PAPILLA; UPREGULATION; WESTERN BLOTTING;

EID: 84886241365     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2013.07.008     Document Type: Article

References (39)

1. Jahagirdar B.N., Verfaillie C.M. Multipotent adult progenitor cell and stem cell plasticity. Stem Cell Rev. 2005, 1:53-59.
2. Phinney D.G., Prockop D.J. Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair - current views. Stem Cells 2007, 25:2896-2902.
3. Seo B.M., Miura M., Gronthos S., Bartold P.M., Batouli S., Brahim J., Young M., Robey P.G., Wang C.Y., Shi S. Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet 2004, 364:149-155.
4. Gronthos S., Mankani M., Brahim J., Robey P.G., Shi S. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc. Natl. Acad. Sci. U.S.A. 2000, 97:13625-13630.
5. Miura M., Gronthos S., Zhao M., Lu B., Fisher L.W., Robey P.G., Shi S. SHED: stem cells from human exfoliated deciduous teeth. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:5807-5812.
6. Sonoyama W., Liu Y., Yamaza T., Tuan R.S., Wang S., Shi S., Huang G.T. Characterization of the apical papilla and its residing stem cells from human immature permanent teeth: a pilot study. J. Endod. 2008, 34:166-171.
7. d'Aquino R., Graziano A., Sampaolesi M., Laino G., Pirozzi G., De Rosa A., Papaccio G. Human postnatal dental pulp cells co-differentiate into osteoblasts and endotheliocytes: a pivotal synergy leading to adult bone tissue formation. Cell Death Differ. 2007, 14:1162-1171.
8. Laino G., d'Aquino R., Graziano A., Lanza V., Carinci F., Naro F., Pirozzi G., Papaccio G. A new population of human adult dental pulp stem cells: a useful source of living autologous fibrous bone tissue (LAB). J. Bone Miner. Res. 2005, 20:1394-1402.
9. Feng J., Mantesso A., De Bari C., Nishiyama A., Sharpe P.T. Dual origin of mesenchymal stem cells contributing to organ growth and repair. Proc. Natl. Acad. Sci. U.S.A 2011, 108:6503-6508.
10. Paino F., Ricci G., De Rosa A., D'Aquino R., Laino L., Pirozzi G., Tirino V., Papaccio G. Ecto-mesenchymal stem cells from dental pulp are committed to differentiate into active melanocytes. Eur. Cell Mater. 2010, 20:295-305.
11. Spath L., Rotilio V., Alessandrini M., Gambara G., De Angelis L., Mancini M., Mitsiadis T.A., Vivarelli E., Naro F., Filippini A., Papaccio G. Explant-derived human dental pulp stem cells enhance differentiation and proliferation potentials. J. Cell Mol. Med. 2010, 14:1635-1644.
12. Graziano A., d'Aquino R., Laino G., Proto A., Giuliano M.T., Pirozzi G., De Rosa A., Di Napoli D., Papaccio G. Human CD34+ stem cells produce bone nodules in vivo. Cell Prolif. 2008, 41:1-11.
13. Wang J., Wang X., Sun Z., Wang X., Yang H., Shi S., Wang S. Stem cells from human-exfoliated deciduous teeth can differentiate into dopaminergic neuron-like cells. Stem Cells Dev. 2010, 19:1375-1383.
14. Cenciarelli C., Chiaur D.S., Guardavaccaro D., Parks W., Vidal M., Pagano M. Identification of a family of human F-box proteins. Curr. Biol. 1999, 9:1177-1179.
15. Tsukada Y., Fang J., Erdjument-Bromage H., Warren M.E., Borchers C.H., Tempst P., Zhang Y. Histone demethylation by a family of JmjC domain-containing proteins. Nature 2006, 439:811-816.
16. Winston J.T., Koepp D.M., Zhu C., Elledge S.J., Harper J.W. A family of mammalian F-box proteins. Curr. Biol. 1999, 9:1180-1182.
17. Clissold P.M., Ponting C.P. JmjC: cupin metalloenzyme-like domains in jumonji, hairless and phospholipase A2beta. Trends Biochem. Sci. 2001, 26:7-9.
18. Liang G., He J., Zhang Y. Kdm2b promotes induced pluripotent stem cell generation by facilitating gene activation early in reprogramming. Nat. Cell. Biol. 2012, 14:457-466.
19. Wang T., Chen K., Zeng X., Yang J., Wu Y., Shi X., Qin B., Zeng L., Esteban M.A., Pan G., Pei D. The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner. Cell Stem Cell 2011, 9:575-587.
20. Zhou J.C., Blackledge N.P., Farcas A.M., Klose R.J. Recognition of CpG island chromatin by KDM2A requires direct and specific interaction with linker DNA. Mol. Cell Biol. 2013, 32:479-489.
21. Du J., Ma Y., Ma P., Wang S., Fan Z. Demethylation of epiregulin gene by histone demethylase FBXL11 and BCL6 corepressor inhibits osteo/dentinogenic differentiation. Stem Cells 2013, 31:126-136.
22. Gao R., Dong R., Du J., Ma P., Wang S., Fan Z. Depletion of histone demethylase KDM2A inhibited cell proliferation of stem cells from apical papilla by de-repression of p15(INK4B) and p27 (Kip1.). Mol. Cell Biochem. 2013, 379:115-122.
23. Bustin S.A. Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. J. Mol. Endocrinol. 2000, 25:169-193.
24. Liu Y., Zheng Y., Ding G., Fang D., Zhang C., Bartold P.M., Gronthos S., Shi S., Wang S. Periodontal ligament stem cell-mediated treatment for periodontitis in miniature swine. Stem Cells 2008, 26:1065-1073.
25. Ding G., Liu Y., Wang W., Wei F., Liu D., Fan Z., An Y., Zhang C., Wang S. Allogeneic periodontal ligament stem cell therapy for periodontitis in swine. Stem Cells 2010, 28:1829-1838.
26. d'Aquino R., De Rosa A., Lanza V., Tirino V., Laino L., Graziano A., Desiderio V., Laino G., Papaccio G. Human mandible bone defect repair by the grafting of dental pulp stem/progenitor cells and collagen sponge biocomplexes. Eur. Cell Mater. 2009, 18:75-83.
27. Deskins D.L., Bastakoty D., Saraswati S., Shinar A., Holt G.E., Young P.P. Human mesenchymal stromal cells: identifying assays to predict potency for therapeutic selection. Stem Cells Transl. Med. 2013, 2:151-158.
28. Giuliani A., Manescu A., Langer M., Rustichelli F., Desiderio V., Paino F., De Rosa A., Laino L., d'Aquino R., Tirino V., Papaccio G. Three years after transplants in human mandibles, histological and in-line holotomography revealed that stem cells regenerated a compact rather than a spongy bone: biological and clinical implications. Stem Cells Transl. Med. 2013, 2:316-324.
29. Han J.W., Yoon Y.S. Epigenetic landscape of pluripotent stem cells. Antioxid. Redox. Signal 2012, 17:205-223.
30. Watanabe A., Yamada Y., Yamanaka S. Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier. Philos. Trans. R. Soc. London B Biol. Sci. 2013, 368:20120292.
31. Jin J., Cardozo T., Lovering R.C., Elledge S.J., Pagano M., Harper J.W. Systematic analysis and nomenclature of mammalian F-box proteins. Genes Dev. 2004, 18:2573-2580.
32. Frescas D., Guardavaccaro D., Kuchay S.M., Kato H., Poleshko A., Basrur V., Elenitoba-Johnson K.S., Katz R.A., Pagano M. KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state. Cell Cycle 2008, 7:3539-3547.
33. Iuchi S., Green H. Lysine-specific demethylase 2A (KDM2A) normalizes human embryonic stem cell derived keratinocytes. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:9442-9447.
34. Miles R.R., Crockett D.K., Lim M.S., Elenitoba-Johnson K.S. Analysis of BCL6-interacting proteins by tandem mass spectrometry. Mol. Cell Proteomics 2005, 4:1898-1909.
35. Lu T., Jackson M.W., Singhi A.D., Kandel E.S., Yang M., Zhang Y., Gudkov A.V., Stark G.R. Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFkappaB. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:16339-16344.
36. Lu T., Jackson M.W., Wang B., Yang M., Chance M.R., Miyagi M., Gudkov A.V., Stark G.R. Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:46-51.
37. Wei F., Qu C., Song T., Ding G., Fan Z., Liu D., Liu Y., Zhang C., Shi S., Wang S. Vitamin C treatment promotes mesenchymal stem cell sheet formation and tissue regeneration by elevating telomerase activity. J. Cell Physiol. 2012, 227:3216-3224.
38. Gearhart M.D., Corcoran C.M., Wamstad J.A., Bardwell V.J. Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets. Mol. Cell Biol. 2006, 26:6880-6889.
39. Fan Z., Yamaza T., Lee J.S., Yu J., Wang S., Fan G., Shi S., Wang C.Y. BCOR regulates mesenchymal stem cell function by epigenetic mechanisms. Nat. Cell Biol. 2009, 11:1002-1009.