Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells

Journal of Biological Chemistry

Volumn 289, Issue 11, 2014, Pages 7483-7496

  Dhar, Shilpa S ^a   Alam, Hunain ^a   Li, Na ^a   Wagner, Klaus W ^a,e   Chung, Jimyung ^b   Ahn, Yeo Won ^c   Lee, Min Gyu ^a,d  

^a UNIVERSITY OF TEXAS   (United States)

^b Yonsei University   (South Korea)

^c EMORY UNIVERSITY   (United States)

^d UNIVERSITY OF TEXAS   (United States)

^e UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGICAL ORGANS; CYTOLOGY; DISEASES; ENZYME INHIBITION; FUNCTIONAL GROUPS; GENE EXPRESSION;

ANTAGONISTIC EFFECTS; CANCER DEVELOPMENT; ECTOPIC EXPRESSIONS; EPIGENETIC MECHANISMS; HISTONE DEACETYLASES; HISTONE METHYLTRANSFERASES; NON SMALL CELL LUNG CANCER; TRANSCRIPTIONAL REPRESSION;

CELLS;

HISTONE DEACETYLASE 3; HISTONE DEMETHYLASE; HISTONE DEMETHYLASE KDM2A; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CARCINOGENICITY; CATALYSIS; CDK6 GENE; CELL INVASION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; EPIGENETICS; GENE; GENE DELETION; GENE IDENTIFICATION; GENE INTERACTION; GENE LOCATION; GENE OVEREXPRESSION; GENE SILENCING; HDAC3 GENE; HUMAN; HUMAN CELL; KDM2A GENE; LUNG NON SMALL CELL CANCER; MALE; MOUSE; MOUSE MODEL; NANOS1 GENE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION; TUMOR XENOGRAFT;

CHROMATIN; GENE REGULATION; HISTONE MODIFICATION; LUNG CANCER; TRANSCRIPTION REPRESSOR;

ANIMALS; CARCINOMA, NON-SMALL-CELL LUNG; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE 6; EPIGENESIS, GENETIC; F-BOX PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HISTONE DEACETYLASES; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; LUNG NEOPLASMS; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PROMOTER REGIONS, GENETIC; RNA-BINDING PROTEINS; TRANSCRIPTION, GENETIC;

EID: 84896291131     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.521625     Document Type: Article

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