The water-extracted Ampelopsis brevipedunculata downregulates IL-1β, CCL5, and COX-2 expression via inhibition of PKC-mediated JNK/NF-κB signaling pathways in human monocytic cells

Journal of Pharmacological Sciences

Volumn 126, Issue 4, 2014, Pages 359-369

  Le, Minh Quan ^a   Kim, Man Sub ^a   Song, Yong Seok ^a   Noh, Whoe Nyoung ^b   Chun, Se Chul ^b   Yoon, Do Young ^a  

^a Laboratory of Cellular Biology and Immunobiochemistry   (South Korea)

^b Konkuk University   (South Korea)

Author keywords

Ampelopsis brevipedunculata; Anti inflammation; IL 1 ; PMA; THP 1

Indexed keywords

AMPELOPSIS BREVIPEDUNCULATA EXTRACT; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL 13 ACETATE 12 MYRISTATE; PLANT EXTRACT; PROTEIN KINASE C; RANTES; UNCLASSIFIED DRUG; WATER; AUTACOID; POLYSACCHARIDE; PTGS2 PROTEIN, HUMAN;

AMPELOPSIS; AMPELOPSIS BREVIPEDUNCULATA; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOSOL; DOSE RESPONSE; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG DETERMINATION; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MACROPHAGE; MONOCYTE; PLANT LEAF; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SOLVENT EXTRACTION; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION; INFLAMMATION; ISOLATION AND PURIFICATION; METABOLISM; PHYTOTHERAPY;

AMPELOPSIS; ANTI-INFLAMMATORY AGENTS; CELLS, CULTURED; CHEMOKINE CCL5; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GENE EXPRESSION; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; MAP KINASE SIGNALING SYSTEM; MONOCYTES; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; POLYSACCHARIDES; PROTEIN KINASE C; WATER;

EID: 84920834036     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.14168FP     Document Type: Article

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