Pi3kcb links Hippo-YAP and PI3K-AKT signaling pathways to promote cardiomyocyte proliferation and survival

Circulation Research

Volumn 116, Issue 1, 2015, Pages 35-45

  Lin, Zhiqiang ^a   Zhou, Pingzhu ^a   Von Gise, Alexander ^a,b   Gu, Fei ^a   Ma, Qing ^a   Chen, Jinghai ^a   Guo, Haidong ^a,c   Van Gorp, Pim R R ^a,d   Wang, Da Zhi ^a,e   Pu, William T ^a,e  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HANNOVER MEDICAL SCHOOL   (Germany)

^c SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^d LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^e HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

AAV; Akt; heart failure; Hippo; PI3 kinase; Pik3cb; regeneration; Yap

Indexed keywords

HIPPO KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PI3KCB PROTEIN; PROTEIN KINASE B; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; YES ASSOCIATED PROTEIN; APOPTOSIS REGULATORY PROTEIN; HIPPO PROTEIN, MOUSE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PROTEIN SERINE THREONINE KINASE; YAP PROTEIN, RAT;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; ENHANCER REGION; GENE EXPRESSION PROFILING; GENE SILENCING; HEART FUNCTION; HEART MUSCLE CELL; INTRON; MITOGENESIS; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; ANIMAL; BIOSYNTHESIS; CARDIAC MUSCLE CELL; CELL CULTURE; GENETICS; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS REGULATORY PROTEINS; BASE SEQUENCE; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CLASS IB PHOSPHATIDYLINOSITOL 3-KINASE; MICE; MOLECULAR SEQUENCE DATA; MYOCYTES, CARDIAC; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; SIGNAL TRANSDUCTION;

EID: 84920768917     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.115.304457     Document Type: Article

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