The molecular basis of primary aldosteronism: From chimeric gene to channelopathy

Current Opinion in Pharmacology

Volumn 21, Issue , 2015, Pages 35-42

  Lenzini, Livia ^a   Rossi, Gian Paolo ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE SYNTHASE; CALCIUM ION; CORTICOTROPIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR3.4; PARATHYROID HORMONE; POTASSIUM CHANNEL; POTASSIUM ION; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM ION; TWIK RELATED ACID SENSITIVE POTASSIUM CHANNEL; TWIK RELATED ACID SENSITIVE POTASSIUM CHANNEL 1; TWIK RELATED ACID SENSITIVE POTASSIUM CHANNEL 2; TWIK RELATED ACID SENSITIVE POTASSIUM CHANNEL 3; UNCLASSIFIED DRUG; CHIMERIC PROTEIN; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; KCNJ5 PROTEIN, HUMAN; STEROID 11BETA MONOOXYGENASE; TANDEM PORE DOMAIN POTASSIUM CHANNEL;

ADRENAL HYPERPLASIA; ALDOSTERONE RELEASE; AMINO ACID SUBSTITUTION; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CALCIUM TRANSPORT; CELL MEMBRANE DEPOLARIZATION; CHANNELOPATHY; CHIMERA; CHROMOSOME ANALYSIS; CYP11B2 GENE; FAMILIAL HYPERALDOSTERONISM TYPE 1; FAMILIAL HYPERALDOSTERONISM TYPE 2; FAMILIAL HYPERALDOSTERONISM TYPE 3; GENE EXPRESSION REGULATION; GENETIC SCREENING; HUMAN; KCNJ5 GENE; NONHUMAN; PRIMARY HYPERALDOSTERONISM; PROTEIN EXPRESSION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SODIUM CONDUCTANCE; SODIUM RETENTION; SOMATIC MUTATION; TASK 1 GENE; TASK 2 GENE; TASK 3 GENE; ANIMAL; GENETICS; HYPERALDOSTERONISM; IMMUNOLOGY; METABOLISM; PHYSIOLOGY;

ANIMALS; CHANNELOPATHIES; CYTOCHROME P-450 CYP11B2; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; HUMANS; HYPERALDOSTERONISM; MUTANT CHIMERIC PROTEINS; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; STEROID 11-BETA-HYDROXYLASE;

EID: 84920747068     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2014.12.005     Document Type: Review

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