Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension

Nature Genetics

Volumn 45, Issue 4, 2013, Pages 440-444

  Beuschlein, Felix ^a   Boulkroun, Sheerazed ^b,c   Osswald, Andrea ^a   Wieland, Thomas ^d   Nielsen, Hang N ^e   Lichtenauer, Urs D ^a   Penton, David ^f   Schack, Vivien R ^e   Amar, Laurence ^b,c,g   Fischer, Evelyn ^a   Walther, Anett ^d   Tauber, Philipp ^f   Schwarzmayr, Thomas ^d   Diener, Susanne ^d   Graf, Elisabeth ^d   Allolio, Bruno ^h   Samson Couterie, Benoit ^b,c   Benecke, Arndt ⁱ   Quinkler, Marcus ^j   Fallo, Francesco ^k   Plouin, Pierre Francois ^b,c,g   Mantero, Franco ^k   Meitinger, Thomas ^d,l,m   Mulatero, Paolo ⁿ   Jeunemaitre, Xavier ^b,c,g   Warth, Richard ^f   Vilsen, Bente ^e   Zennaro, Maria Christina ^b,c,g   Strom, Tim M ^d,l   Reincke, Martin ^a   more..

^a UNIVERSITY OF MUNICH   (Germany)

^b INSERM   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

^e AARHUS UNIVERSITY   (Denmark)

^f UNIVERSITY OF REGENSBURG   (Germany)

^g HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^h UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

ⁱ CNRS   (France)

^j CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^k UNIVERSITY OF PADOVA   (Italy)

^l TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^m DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

ⁿ UNIVERSITY OF TURIN   (Italy)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; SODIUM;

ACTION POTENTIAL; ALDOSTERONE BLOOD LEVEL; ALDOSTERONE RELEASE; ARTICLE; ATP1A1 GENE; ATP2B3 GENE; BINDING SITE; CALCIUM CELL LEVEL; CELL PH; CONFORMATIONAL TRANSITION; DEPOLARIZATION; DIASTOLIC BLOOD PRESSURE; HEARING IMPAIRMENT; HOMEOSTASIS; HUMAN; HYPERPOLARIZATION; HYPERTENSION; IMMUNOREACTIVITY; IN VITRO STUDY; MEMBRANE STEADY POTENTIAL; ONCOGENE; POTASSIUM BLOOD LEVEL; PRIMARY HYPERALDOSTERONISM; PRIORITY JOURNAL; PURIFYING SELECTION; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; SODIUM BLOOD LEVEL; SOMATIC MUTATION; X CHROMOSOME; ZONA FASCICULATA; ZONA GLOMERULOSA;

ADRENAL CORTEX NEOPLASMS; ADRENOCORTICAL ADENOMA; ALDOSTERONE; CALCIUM; CELLS, CULTURED; ELECTROPHYSIOLOGY; HUMANS; HYPERTENSION; IMMUNOENZYME TECHNIQUES; MUTATION; PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASES; POTASSIUM; SODIUM; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 84875737352     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2550     Document Type: Article

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