The effect of ROCK on TNF-α-induced CXCL8 secretion by intestinal epithelial cell lines is mediated through MKK4 and JNK signaling

Cellular Immunology

Volumn 293, Issue 2, 2015, Pages 80-86

  Perey, Aaron C ^a   Weishaar, Isabelle M ^a   McGee, Dennis W ^a  

^a BINGHAMTON UNIVERSITY   (United States)

Author keywords

CXCL8; Intestinal epithelial; JNK; MKK4; ROCK; TNF

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; DACTINOMYCIN; I KAPPA B ALPHA; INTERLEUKIN 1; INTERLEUKIN 8; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; RHO KINASE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; AMIDE; ENZYME INHIBITOR; PYRIDINE DERIVATIVE; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; CACO 2 CELL LINE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFECT; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; INTRACELLULAR SIGNALING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CYTOLOGY; EPITHELIUM CELL; GENETICS; IMMUNOLOGY; INFLAMMATION; INTESTINE; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SECRETION (PROCESS); SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AMIDES; BLOTTING, WESTERN; CACO-2 CELLS; ENZYME INHIBITORS; EPITHELIAL CELLS; HUMANS; INFLAMMATION; INTERLEUKIN-8; INTESTINES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE 4; PHOSPHORYLATION; PYRIDINES; REAL-TIME POLYMERASE CHAIN REACTION; RHO-ASSOCIATED KINASES; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84920661977     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2014.12.011     Document Type: Article

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