Rho-kinase mediates lysophosphatidic acid-induced IL-8 and MCP-1 production via p38 and JNK pathways in human endothelial cells

FEBS Letters

Volumn 584, Issue 13, 2010, Pages 2827-2832

  Shimada, Hideaki ^a   Rajagopalan, Lakshman E ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Chemokine; Endothelial cell; JNK; Lysophosphatidic acid; NF B p65; P38 MAP kinase; Rho kinase

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; LYSOPHOSPHATIDIC ACID; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; RHO KINASE; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

BLOTTING, WESTERN; CELLS, CULTURED; CHEMOKINE CCL2; ENDOTHELIAL CELLS; HUMANS; INTERLEUKIN-8; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LYSOPHOSPHOLIPIDS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA;

EID: 77953701821     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.04.064     Document Type: Article

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