-
1
-
-
84859426282
-
MEROPS: The database of proteolytic enzymes, their substrates and inhibitors
-
N. D. Rawlings, A. J. Barrett, and A. Bateman, "MEROPS: the database of proteolytic enzymes, their substrates and inhibitors, " Nucleic Acids Research, vol. 40, no. 1, pp. D343-D350, 2012.
-
(2012)
Nucleic Acids Research
, vol.40
, Issue.1
, pp. D343-D350
-
-
Rawlings, N.D.1
Barrett, A.J.2
Bateman, A.3
-
2
-
-
2942718876
-
Comprehensive search for cysteine cathepsins in the human genome
-
A. Rossi, Q. Deveraux, B. Turk, and A. Sali, "Comprehensive search for cysteine cathepsins in the human genome, " Biological Chemistry, vol. 385, no. 5, pp. 363-372, 2004.
-
(2004)
Biological Chemistry
, vol.385
, Issue.5
, pp. 363-372
-
-
Rossi, A.1
Deveraux, Q.2
Turk, B.3
Sali, A.4
-
3
-
-
82755161948
-
Cysteine cathepsins: From structure, function and regulation to new frontiers
-
V. Turk, V. Stoka, O. Vasiljeva et al. , "Cysteine cathepsins: from structure, function and regulation to new frontiers, " Biochimica et Biophysica Acta-Proteins and Proteomics, vol. 1824, no. 1, pp. 68-88, 2012.
-
(2012)
Biochimica et Biophysica Acta-Proteins and Proteomics
, vol.1824
, Issue.1
, pp. 68-88
-
-
Turk, V.1
Stoka, V.2
Vasiljeva, O.3
-
4
-
-
84881602259
-
Papain-like peptidases: Structure, function, and evolution
-
M. Novinec and B. Lenarcic, "Papain-like peptidases: Structure, function, and evolution, " Biomolecular Concepts, vol. 4, no. 3, pp. 287-308, 2013.
-
(2013)
Biomolecular Concepts
, vol.4
, Issue.3
, pp. 287-308
-
-
Novinec, M.1
Lenarcic, B.2
-
5
-
-
33846164404
-
Emerging roles of cysteine cathepsins in disease and theirpotential as drug targets
-
O. Vasiljeva, T. Reinheckel, C. Peters, D. Turk, V. Turk, and B. Turk, "Emerging roles of cysteine cathepsins in disease and theirpotential as drug targets, " Current Pharmaceutical Design, vol. 13, no. 4, pp. 387-403, 2007.
-
(2007)
Current Pharmaceutical Design
, vol.13
, Issue.4
, pp. 387-403
-
-
Vasiljeva, O.1
Reinheckel, T.2
Peters, C.3
Turk, D.4
Turk, V.5
Turk, B.6
-
6
-
-
0014211618
-
On the size of the active site in proteases. I. Papain
-
I. Schechter and A. Berger, "On the size of the active site in proteases. I. Papain, " Biochemical and Biophysical Research Communications, vol. 27, no. 2, pp. 157-162, 1967.
-
(1967)
Biochemical and Biophysical Research Communications
, vol.27
, Issue.2
, pp. 157-162
-
-
Schechter, I.1
Berger, A.2
-
7
-
-
0345310073
-
Revised definition of substrate binding sites of papain-like cysteine proteases
-
D. Turk, G. Guncar, M. Podobnik, and B. Turk, "Revised definition of substrate binding sites of papain-like cysteine proteases, " Biological Chemistry, vol. 379, no. 2, pp. 137-147, 1998.
-
(1998)
Biological Chemistry
, vol.379
, Issue.2
, pp. 137-147
-
-
Turk, D.1
Guncar, G.2
Podobnik, M.3
Turk, B.4
-
8
-
-
0028831635
-
Molecular cloning of human cDNA for cathepsin K: Novel cysteine proteinase predominantly expressed in bone
-
T. Inaoka, G. Bilbe, O. Ishibashi, K.-I. Tezuka, M. Kumegawa, and T. Kokubo, "Molecular cloning of human cDNA for cathepsin K: novel cysteine proteinase predominantly expressed in bone, " Biochemical and Biophysical Research Communications, vol. 206, no. 1, pp. 89-96, 1995.
-
(1995)
Biochemical and Biophysical Research Communications
, vol.206
, Issue.1
, pp. 89-96
-
-
Inaoka, T.1
Bilbe, G.2
Ishibashi, O.3
Tezuka, K.-I.4
Kumegawa, M.5
Kokubo, T.6
-
9
-
-
0035185895
-
Cathepsin K is a critical protease in synovial fibroblast-mediated collagen degradation
-
W.-S. Hou, Z. Li, R. E. Gordon et al. , "Cathepsin K is a critical protease in synovial fibroblast-mediated collagen degradation, " The American Journal of Pathology, vol. 159, no. 6, pp. 2167-2177, 2001.
-
(2001)
The American Journal of Pathology
, vol.159
, Issue.6
, pp. 2167-2177
-
-
Hou, W.-S.1
Li, Z.2
Gordon, R.E.3
-
10
-
-
84881539601
-
Cathepsin K: A unique collagenolytic cysteine peptidase
-
M. Novinec and B. Lenarcic, "Cathepsin K: a unique collagenolytic cysteine peptidase, " Biological Chemistry, vol. 394, no. 9, pp. 1163-1179, 2013.
-
(2013)
Biological Chemistry
, vol.394
, Issue.9
, pp. 1163-1179
-
-
Novinec, M.1
Lenarcic, B.2
-
11
-
-
33646513917
-
Cysteine cathepsins in the immune response
-
T. Zavasnik-Bergant and B. Turk, "Cysteine cathepsins in the immune response, " Tissue Antigens, vol. 67, no. 5, pp. 349-355, 2006.
-
(2006)
Tissue Antigens
, vol.67
, Issue.5
, pp. 349-355
-
-
Zavasnik-Bergant, T.1
Turk, B.2
-
12
-
-
0038687865
-
Human cathepsin v functional expression, tissue distribution, electrostatic surface potential, enzymatic characterization, and chromosomal localization
-
D. Brömme, Z. Li, M. Barnes, and E. Mehler, "Human cathepsin V functional expression, tissue distribution, electrostatic surface potential, enzymatic characterization, and chromosomal localization, " Biochemistry, vol. 38, no. 8, pp. 2377-2385, 1999.
-
(1999)
Biochemistry
, vol.38
, Issue.8
, pp. 2377-2385
-
-
Brömme, D.1
Li, Z.2
Barnes, M.3
Mehler, E.4
-
13
-
-
58149196159
-
Cathepsin W expressed exclusively in CD8+ T cells and NK cells, is secreted during target cell killing but is not essential for cytotoxicity in human CTLs
-
C. Stoeckle, C. Gouttefangeas, M. Hammer, E. Weber, A. Melms, and E. Tolosa, "Cathepsin W expressed exclusively in CD8+ T cells and NK cells, is secreted during target cell killing but is not essential for cytotoxicity in human CTLs, " Experimental Hematology, vol. 37, no. 2, pp. 266-275, 2009.
-
(2009)
Experimental Hematology
, vol.37
, Issue.2
, pp. 266-275
-
-
Stoeckle, C.1
Gouttefangeas, C.2
Hammer, M.3
Weber, E.4
Melms, A.5
Tolosa, E.6
-
14
-
-
0034110252
-
Glycosaminoglycan conformation: Do aqueous molecular dynamics simulations agree with xray fiber diffraction?
-
A. Almond and J. K. Sheehan, "Glycosaminoglycan conformation: do aqueous molecular dynamics simulations agree with xray fiber diffraction?" Glycobiology, vol. 10, no. 3, pp. 329-338, 2000.
-
(2000)
Glycobiology
, vol.10
, Issue.3
, pp. 329-338
-
-
Almond, A.1
Sheehan, J.K.2
-
15
-
-
0030584678
-
Structure of rat procathepsin B: Model for inhibition of cysteine protease activity by the proregion
-
M. Cygler, J. Sivaraman, P. Grochulski, R. Coulombe, A. C. Storer, and J. S. Mort, "Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion, " Structure, vol. 4, no. 4, pp. 405-416, 1996.
-
(1996)
Structure
, vol.4
, Issue.4
, pp. 405-416
-
-
Cygler, M.1
Sivaraman, J.2
Grochulski, P.3
Coulombe, R.4
Storer, A.C.5
Mort, J.S.6
-
16
-
-
0029902382
-
Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment
-
R. Coulombe, P. Grochulski, J. Sivaraman, R. Ménard, J. S. Mort, and M. Cygler, "Structure of human procathepsin L reveals the molecular basis of inhibition by the prosegment, " EMBO Journal, vol. 15, no. 20, pp. 5492-5503, 1996.
-
(1996)
EMBO Journal
, vol.15
, Issue.20
, pp. 5492-5503
-
-
Coulombe, R.1
Grochulski, P.2
Sivaraman, J.3
Ménard, R.4
Mort, J.S.5
Cygler, M.6
-
17
-
-
0344938353
-
Crystal structure of wild-type human procathepsin K
-
J. Sivaraman, M. Lalumìere, R. Ménard, andM. Cygler, "Crystal structure of wild-type human procathepsin K, " Protein Science, vol. 8, no. 2, pp. 283-290, 1999.
-
(1999)
Protein Science
, vol.8
, Issue.2
, pp. 283-290
-
-
Sivaraman, J.1
Lalumìere, M.2
Ménard, R.3
Cygler, M.4
-
18
-
-
0029976244
-
Crystal structures of human procathepsin B at 3. 2 and 3. 3 å resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide
-
D. Turk, M. Podobnik, R. Kuhelj, M. Dolinar, and V. Turk, "Crystal structures of human procathepsin B at 3. 2 and 3. 3 å resolution reveal an interaction motif between a papain-like cysteine protease and its propeptide, " FEBS Letters, vol. 384, no. 3, pp. 211-214, 1996.
-
(1996)
FEBS Letters
, vol.384
, Issue.3
, pp. 211-214
-
-
Turk, D.1
Podobnik, M.2
Kuhelj, R.3
Dolinar, M.4
Turk, V.5
-
19
-
-
0031554904
-
Crystal structure of the wild-type human procathepsin B at 2. 5 å resolution reveals the native active site of a papain-like cysteine protease zymogen
-
M. Podobnik, R. Kuhelj, V. Turk, andD. Turk, "Crystal structure of the wild-type human procathepsin B at 2. 5 å resolution reveals the native active site of a papain-like cysteine protease zymogen, " Journal of Molecular Biology, vol. 271, no. 5, pp. 774-788, 1997.
-
(1997)
Journal of Molecular Biology
, vol.271
, Issue.5
, pp. 774-788
-
-
Podobnik, M.1
Kuhelj, R.2
Turk, V.3
Turk, D.4
-
20
-
-
0032859935
-
Autocatalytic processing of recombinant human procathepsin B is a bimolecular process
-
J. Rozman, J. Stojan, R. Kuhelj, V. Turk, and B. Turk, "Autocatalytic processing of recombinant human procathepsin B is a bimolecular process, " FEBS Letters, vol. 459, no. 3, pp. 358-362, 1999.
-
(1999)
FEBS Letters
, vol.459
, Issue.3
, pp. 358-362
-
-
Rozman, J.1
Stojan, J.2
Kuhelj, R.3
Turk, V.4
Turk, B.5
-
21
-
-
58449134643
-
Autocatalytic processing of procathepsin B is triggered by proenzyme activity
-
J. Rozman Pungercar, D. Caglic, M. Sajid et al. , "Autocatalytic processing of procathepsin B is triggered by proenzyme activity, " FEBS Journal, vol. 276, no. 3, pp. 660-668, 2009.
-
(2009)
FEBS Journal
, vol.276
, Issue.3
, pp. 660-668
-
-
Rozman Pungercar, J.1
Caglic, D.2
Sajid, M.3
-
22
-
-
17044379501
-
Proteinaceous cysteine protease inhibitors
-
G. Dubin, "Proteinaceous cysteine protease inhibitors, " Cellular and Molecular Life Sciences, vol. 62, no. 6, pp. 653-669, 2005.
-
(2005)
Cellular and Molecular Life Sciences
, vol.62
, Issue.6
, pp. 653-669
-
-
Dubin, G.1
-
23
-
-
0035986219
-
Regulating cysteine protease activity: Essential role of protease inhibitors as guardians and regulators
-
B. Turk, D. Turk, and G. S. Salvesen, "Regulating cysteine protease activity: essential role of protease inhibitors as guardians and regulators, " Current Pharmaceutical Design, vol. 8, no. 18, pp. 1623-1637, 2002.
-
(2002)
Current Pharmaceutical Design
, vol.8
, Issue.18
, pp. 1623-1637
-
-
Turk, B.1
Turk, D.2
Salvesen, G.S.3
-
24
-
-
0030918546
-
Structural and functional aspects of papain-like cysteine proteinases and their protein inhibitors
-
B. Turk, V. Turk, andD. Turk, "Structural and functional aspects of papain-like cysteine proteinases and their protein inhibitors, " Biological Chemistry, vol. 378, no. 3-4, pp. 141-150, 1997.
-
(1997)
Biological Chemistry
, vol.378
, Issue.3-4
, pp. 141-150
-
-
Turk, B.1
Turk, V.2
Turk, D.3
-
25
-
-
0038835365
-
Thyropins-new structurally related proteinase inhibitors
-
B. Lenarcic and T. Bevec, "Thyropins-new structurally related proteinase inhibitors, " The Biological Chemistry, vol. 379, no. 2, pp. 105-111, 1998.
-
(1998)
The Biological Chemistry
, vol.379
, Issue.2
, pp. 105-111
-
-
Lenarcic, B.1
Bevec, T.2
-
26
-
-
0016817563
-
Inhibition of leucocytic lysosomal enzymes by glycosaminoglycans in vitro
-
J. L. Avila and J. Convit, "Inhibition of leucocytic lysosomal enzymes by glycosaminoglycans in vitro, " Biochemical Journal, vol. 152, no. 1, pp. 57-64, 1975.
-
(1975)
Biochemical Journal
, vol.152
, Issue.1
, pp. 57-64
-
-
Avila, J.L.1
Convit, J.2
-
27
-
-
84903543514
-
Cysteine cathepsins and extracellular matrix degradation
-
M. Fonović and B. Turk, "Cysteine cathepsins and extracellular matrix degradation, " Biochimica et Biophysica Acta-General Subjects, vol. 1840, no. 8, pp. 2560-2570, 2014.
-
(2014)
Biochimica et Biophysica Acta-General Subjects
, vol.1840
, Issue.8
, pp. 2560-2570
-
-
Fonović, M.1
Turk, B.2
-
28
-
-
0029590746
-
Procathepsin L degrades extracellular matrix proteins in the presence of glycosaminoglycans in vitro
-
K. Ishidoh and E. Kominami, "Procathepsin L degrades extracellular matrix proteins in the presence of glycosaminoglycans in vitro, " Biochemical and Biophysical Research Communications, vol. 217, no. 2, pp. 624-631, 1995.
-
(1995)
Biochemical and Biophysical Research Communications
, vol.217
, Issue.2
, pp. 624-631
-
-
Ishidoh, K.1
Kominami, E.2
-
29
-
-
0027051118
-
Surface activation of procathepsin L
-
R. W. Mason and S. D. Massey, "Surface activation of procathepsin L, " Biochemical and Biophysical Research Communications, vol. 189, no. 3, pp. 1659-1666, 1992.
-
(1992)
Biochemical and Biophysical Research Communications
, vol.189
, Issue.3
, pp. 1659-1666
-
-
Mason, R.W.1
Massey, S.D.2
-
30
-
-
13844276525
-
Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans, "the
-
O. Vasiljeva, M. Dolinar, J. Rozman Pungercar, V. Turk, and B. Turk, "Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans, "The FEBS Letters, vol. 579, no. 5, pp. 1285-1290, 2005.
-
(2005)
FEBS Letters
, vol.579
, Issue.5
, pp. 1285-1290
-
-
Vasiljeva, O.1
Dolinar, M.2
Rozman Pungercar, J.3
Turk, V.4
Turk, B.5
-
31
-
-
36348941660
-
Glycosaminoglycans facilitate procathepsin B activation through disruption of propeptide-mature enzyme interactions
-
D. Caglic, J. Rozman Pungercar, G. Pejler, V. Turk, and B. Turk, "Glycosaminoglycans facilitate procathepsin B activation through disruption of propeptide-mature enzyme interactions, " The Journal of Biological Chemistry, vol. 282, no. 45, pp. 33076-33085, 2007.
-
(2007)
The Journal of Biological Chemistry
, vol.282
, Issue.45
, pp. 33076-33085
-
-
Caglic, D.1
Rozman Pungercar, J.2
Pejler, G.3
Turk, V.4
Turk, B.5
-
32
-
-
0038486742
-
Procongopain from Trypanosoma congolense is processed at basic pH: An unusual feature among cathepsin L-like cysteine proteases
-
C. Serveau, A. Boulangé, F. Lecaille, F. Gauthier, E. Authié, and G. Lalmanach, "Procongopain from Trypanosoma congolense is processed at basic pH: an unusual feature among cathepsin L-like cysteine proteases, " Biological Chemistry, vol. 384, no. 6, pp. 921-927, 2003.
-
(2003)
Biological Chemistry
, vol.384
, Issue.6
, pp. 921-927
-
-
Serveau, C.1
Boulangé, A.2
Lecaille, F.3
Gauthier, F.4
Authié, E.5
Lalmanach, G.6
-
33
-
-
84884275724
-
Binding of chondroitin 4-sulfate to cathepsin S regulates its enzymatic activity
-
J. Sage, F. Mallèvre, F. Barbarin-Costes et al. , "Binding of chondroitin 4-sulfate to cathepsin S regulates its enzymatic activity, " Biochemistry, vol. 52, no. 37, pp. 6487-6498, 2013.
-
(2013)
Biochemistry
, vol.52
, Issue.37
, pp. 6487-6498
-
-
Sage, J.1
Mallèver, F.2
Barbarin-Costes, F.3
-
34
-
-
0345862190
-
Production and activation of recombinant papain-like cysteine proteases
-
D. Brömme, F. S. Nallaseth, and B. Turk, "Production and activation of recombinant papain-like cysteine proteases, " Methods, vol. 32, no. 2, pp. 199-206, 2004.
-
(2004)
Methods
, vol.32
, Issue.2
, pp. 199-206
-
-
Brömme, D.1
Nallaseth, F.S.2
Turk, B.3
-
35
-
-
0028958724
-
The preparation of catalytically active human cathepsin B from its precursor expressed in Escherichia coli in the form of inclusion bodies
-
R. Kuhelj, M. Dolinar, J. Rozman Pungercar, and V. Turk, "The preparation of catalytically active human cathepsin B from its precursor expressed in Escherichia coli in the form of inclusion bodies, " European Journal of Biochemistry, vol. 229, no. 2, pp. 533-539, 1995.
-
(1995)
European Journal of Biochemistry
, vol.229
, Issue.2
, pp. 533-539
-
-
Kuhelj, R.1
Dolinar, M.2
Rozman Pungercar, J.3
Turk, V.4
-
36
-
-
0029935616
-
Folding and activation of human procathepsin S from inclusion bodies produced in Escherichia coli
-
G. Kopitar, M. Dolinar, B. Strukelj, J. Pungercar, and V. Turk, "Folding and activation of human procathepsin S from inclusion bodies produced in Escherichia coli, " European Journal of Biochemistry, vol. 236, no. 2, pp. 558-562, 1996.
-
(1996)
European Journal of Biochemistry
, vol.236
, Issue.2
, pp. 558-562
-
-
Kopitar, G.1
Dolinar, M.2
Strukelj, B.3
Pungercar, J.4
Turk, V.5
-
37
-
-
0035900729
-
Structural requirements and mechanism for heparin-induced activation of a recombinant mouse mast cell tryptase, mouse mast cell protease-6: Formation of active tryptase monomers in the presence of low molecular weight heparin
-
J. Hallgren, D. Spillmann, and G. Pejler, "Structural requirements and mechanism for heparin-induced activation of a recombinant mouse mast cell tryptase, mouse mast cell protease-6: formation of active tryptase monomers in the presence of low molecular weight heparin, " Journal of Biological Chemistry, vol. 276, no. 46, pp. 42774-42781, 2001.
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.46
, pp. 42774-42781
-
-
Hallgren, J.1
Spillmann, D.2
Pejler, G.3
-
38
-
-
33744539889
-
The anti-angiogenicHis/Pro-rich fragment of histidine-rich glycoprotein binds to endothelial cell heparan sulfate in a Zn2+-dependent manner
-
M. Vanwildemeersch, A.-K. Olsson, E. Gottfridsson, L. Claesson-Welsh, U. Lindahl, andD. Spillmann, "The anti-angiogenicHis/Pro-rich fragment of histidine-rich glycoprotein binds to endothelial cell heparan sulfate in a Zn2+-dependent manner, " The Journal of Biological Chemistry, vol. 281, no. 15, pp. 10298-10304, 2006.
-
(2006)
The Journal of Biological Chemistry
, vol.281
, Issue.15
, pp. 10298-10304
-
-
Vanwildemeersch, M.1
Olsson, A.-K.2
Gottfridsson, E.3
Claesson-Welsh, L.4
Lindahl, U.5
Spillmann, D.6
-
39
-
-
37549071494
-
A heparin binding motif on the pro-domain of human procathepsin L mediates zymogen destabilization and activation
-
M. Fairhead, S. M. Kelly, and C. F. van der Walle, "A heparin binding motif on the pro-domain of human procathepsin L mediates zymogen destabilization and activation, " Biochemical and Biophysical Research Communications, vol. 366, no. 3, pp. 862-867, 2008.
-
(2008)
Biochemical and Biophysical Research Communications
, vol.366
, Issue.3
, pp. 862-867
-
-
Fairhead, M.1
Kelly, S.M.2
Walle Der Van, C.F.3
-
40
-
-
0032741501
-
Cysteine proteinase activity regulation: A possible role of heparin and heparin-like glycosaminoglycans
-
P. C. Almeida, I. L. Nantes, C. C. A. Rizzi et al. , "Cysteine proteinase activity regulation: a possible role of heparin and heparin-like glycosaminoglycans, " The Journal of Biological Chemistry, vol. 274, no. 43, pp. 30433-30438, 1999.
-
(1999)
The Journal of Biological Chemistry
, vol.274
, Issue.43
, pp. 30433-30438
-
-
Almeida, P.C.1
Nantes, I.L.2
Rizzi, C.C.A.3
-
41
-
-
0034711762
-
Collagenolytic activity of cathepsin K is specifically modulated by cartilage-resident chondroitin sulfates
-
Z. Li, W. S. Hou, and D. Brömme, "Collagenolytic activity of cathepsin K is specifically modulated by cartilage-resident chondroitin sulfates, " Biochemistry, vol. 39, no. 3, pp. 529-536, 2000.
-
(2000)
Biochemistry
, vol.39
, Issue.3
, pp. 529-536
-
-
Li, Z.1
Hou, W.S.2
Brömme, D.3
-
42
-
-
0029809357
-
Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency
-
B. D. Gelb, G.-P. Shi, H. A. Chapman, and R. J. Desnick, "Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency, " Science, vol. 273, no. 5279, pp. 1236-1239, 1996.
-
(1996)
Science
, vol.273
, Issue.5279
, pp. 1236-1239
-
-
Gelb, B.D.1
Shi, G.-P.2
Chapman, H.A.3
Desnick, R.J.4
-
43
-
-
52049126668
-
The crystal and molecular structures of a cathepsin K:chondroitin sulfate complex
-
Z. Li, M. Kienetz, M. M. Cherney, M. N. G. James, and D. Brömme, "The crystal and molecular structures of a cathepsin K:chondroitin sulfate complex, " Journal of Molecular Biology, vol. 383, no. 1, pp. 78-91, 2008.
-
(2008)
Journal of Molecular Biology
, vol.383
, Issue.1
, pp. 78-91
-
-
Li, Z.1
Kienetz, M.2
Cherney, M.M.3
James, M.N.G.4
Brömme, D.5
-
44
-
-
77954737401
-
Conformational flexibility and allosteric regulation of cathepsin K
-
M. Novinec, L. Kovacic, B. Lenarcic, and A. Baici, "Conformational flexibility and allosteric regulation of cathepsin K, " Biochemical Journal, vol. 429, no. 2, pp. 379-389, 2010.
-
(2010)
Biochemical Journal
, vol.429
, Issue.2
, pp. 379-389
-
-
Novinec, M.1
Kovacic, L.2
Lenarcic, B.3
Baici, A.4
-
45
-
-
0032506007
-
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-Kdeficient mice
-
P. Saftig, E. Hunziker, O. Wehmeyer et al. , "Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-Kdeficient mice, " Proceedings of the National Academy of Sciences of the United States of America, vol. 95, no. 23, pp. 13453-13458, 1998.
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.23
, pp. 13453-13458
-
-
Saftig, P.1
Hunziker, E.2
Wehmeyer, O.3
-
46
-
-
0032080113
-
Human cathepsin K cleaves native type i and II collagens at the N-terminal end of the triple helix
-
W. Kafienah, D. Brömme, D. J. Buttle, L. J. Croucher, and A. P. Hollander, "Human cathepsin K cleaves native type I and II collagens at the N-terminal end of the triple helix, " Biochemical Journal, vol. 331, part 3, pp. 727-732, 1998.
-
(1998)
Biochemical Journal
, vol.331
, Issue.PART 3
, pp. 727-732
-
-
Kafienah, W.1
Brömme, D.2
Buttle, D.J.3
Croucher, L.J.4
Hollander, A.P.5
-
47
-
-
0033610853
-
Thecollagenolytic activity of cathepsin K is unique among mammalian proteinases
-
P. Garnero, O. Borel, I. Byrjalsen et al. , "Thecollagenolytic activity of cathepsin K is unique among mammalian proteinases, " The Journal of Biological Chemistry, vol. 273, no. 48, pp. 32347-32352, 1998.
-
(1998)
The Journal of Biological Chemistry
, vol.273
, Issue.48
, pp. 32347-32352
-
-
Garneroo. Borel, P.1
Byrjalsen, I.2
-
48
-
-
0030026637
-
Human cathepsin O2, a matrix protein-degrading cysteine protease expressed in osteoclasts: Functional expression of human cathepsin O2 in Spodoptera frugiperda and characterization of the enzyme
-
D. Brömme, K. Okamoto, B. B. Wang, and S. Biroc, "Human cathepsin O2, a matrix protein-degrading cysteine protease expressed in osteoclasts: functional expression of human cathepsin O2 in Spodoptera frugiperda and characterization of the enzyme, " Journal of Biological Chemistry, vol. 271, no. 4, pp. 2126-2132, 1996.
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.4
, pp. 2126-2132
-
-
Brömme, D.1
Okamoto, K.2
Wang, B.B.3
Biroc, S.4
-
49
-
-
84862250915
-
Inhibition of cathepsin K for treatment of osteoporosis
-
S. Boonen, E. Rosenberg, F. Claessens, D. Vanderschueren, and S. Papapoulos, "Inhibition of cathepsin K for treatment of osteoporosis, " CurrentOsteoporosis Reports, vol. 10, no. 1, pp. 73-79, 2012.
-
(2012)
CurrentOsteoporosis Reports
, vol.10
, Issue.1
, pp. 73-79
-
-
Boonen, S.1
Rosenberg, E.2
Claessens, F.3
Vanderschueren, D.4
Papapoulos, S.5
-
50
-
-
0038486755
-
Cleavage site specificity of cathepsinKtoward cartilage proteoglycans and protease complex formation
-
W. S. Hou, Z. Li, F. H. Büttner, E. Bartnik, and D. Brömme, "Cleavage site specificity of cathepsinKtoward cartilage proteoglycans and protease complex formation, " Biological Chemistry, vol. 384, no. 6, pp. 891-897, 2003.
-
(2003)
Biological Chemistry
, vol.384
, Issue.6
, pp. 891-897
-
-
Hou, W.S.1
Li, Z.2
Büttner, F.H.3
Bartnik, E.4
Brömme, D.5
-
51
-
-
84860802481
-
Increased type II collagen cleavage by cathepsin K and collagenase activities with aging and osteoarthritis in human articular cartilage
-
article R113
-
V. M. Dejica, J. S. Mort, S. Laverty et al. , "Increased type II collagen cleavage by cathepsin K and collagenase activities with aging and osteoarthritis in human articular cartilage, " Arthritis Research andTherapy, vol. 14, no. 3, article R113, 2012.
-
(2012)
Arthritis Research AndTherapy
, vol.14
, Issue.3
-
-
Dejica, V.M.1
Mort, J.S.2
Laverty, S.3
-
52
-
-
46749086701
-
Cleavage of type II collagen by cathepsin K in human osteoarthritic cartilage
-
V. M. Dejica, J. S. Mort, S. Laverty et al. , "Cleavage of type II collagen by cathepsin K in human osteoarthritic cartilage, " The American Journal of Pathology, vol. 173, no. 1, pp. 161169, 2008.
-
(2008)
The American Journal of Pathology
, vol.173
, Issue.1
, pp. 161-169
-
-
Dejica, V.M.1
Mort, J.S.2
Laverty, S.3
-
53
-
-
1242294466
-
Egulation of collagenase activities of human cathepsins by glycosaminoglycans
-
Z. Li, Y. Yasuda, W. Li et al. , "egulation of collagenase activities of human cathepsins by glycosaminoglycans, " The Journal of Biological Chemistry, vol. 279, no. 7, pp. 5470-5479, 2004.
-
(2004)
The Journal of Biological Chemistry
, vol.279
, Issue.7
, pp. 5470-5479
-
-
Li, Z.1
Yasuda, Y.2
Li, W.3
-
54
-
-
0037047275
-
Collagenase activity of cathepsin K depends on complex formation with chondroitin sulfate
-
Z. Li, W.-S. Hou, C. R. Escalante-Torres, B. D. Gelb, and D. Brömme, "Collagenase activity of cathepsin K depends on complex formation with chondroitin sulfate, " The Journal of Biological Chemistry, vol. 277, no. 32, pp. 28669-28676, 2002.
-
(2002)
The Journal of Biological Chemistry
, vol.277
, Issue.32
, pp. 28669-28676
-
-
Li, Z.1
Hou, W.-S.2
Escalante-Torres, C.R.3
Gelb, B.D.4
Brömme, D.5
-
55
-
-
84863471584
-
CathepsinK preferentially solubilizes matured bonematrix
-
O. Borel, E. Gineyts, C. Bertholon, and P. Garnero, "CathepsinK preferentially solubilizes matured bonematrix, " Calcified Tissue International, vol. 91, no. 1, pp. 32-39, 2012.
-
(2012)
Calcified Tissue International
, vol.91
, Issue.1
, pp. 32-39
-
-
Borel, O.1
Gineyts, E.2
Bertholon, C.3
Garnero, P.4
-
56
-
-
0024021040
-
Conformational flexibility: A new concept for explaining binding and biological properties of iduronic acid-containing glycosaminoglycans
-
B. Casu, M. Petitou, M. Provasoli, andP. Sinaÿ, "Conformational flexibility: a new concept for explaining binding and biological properties of iduronic acid-containing glycosaminoglycans, " Trends in Biochemical Sciences, vol. 13, no. 6, pp. 221-225, 1988.
-
(1988)
Trends in Biochemical Sciences
, vol.13
, Issue.6
, pp. 221-225
-
-
Casu, B.1
Petitou, M.2
Provasoli, M.3
Sinaÿ, P.4
-
57
-
-
0035847011
-
Cathepsin B activity regulation. Heparin-like glycosaminoglycans protect human cathepsin B from alkaline pH-induced inactivation
-
P. C. Almeida, I. L. Nantes, J. R. Chagas et al. , "Cathepsin B activity regulation. Heparin-like glycosaminoglycans protect human cathepsin B from alkaline pH-induced inactivation, " Journal of Biological Chemistry, vol. 276, no. 2, pp. 944-951, 2001.
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.2
, pp. 944-951
-
-
Almeida, P.C.1
Nantes, I.L.2
Chagas, J.R.3
-
58
-
-
0024814219
-
Cathepsin S from bovine spleen. Purification, distribution, intracellular localization and action on proteins
-
H. Kirschke, B. Wiederanders, D. Brömme, and A. Rinne, "Cathepsin S from bovine spleen. Purification, distribution, intracellular localization and action on proteins, " Biochemical Journal, vol. 264, no. 2, pp. 467-473, 1989.
-
(1989)
Biochemical Journal
, vol.264
, Issue.2
, pp. 467-473
-
-
Kirschke, H.1
Wiederanders, B.2
Brömme, D.3
Rinne, A.4
-
59
-
-
2442549710
-
Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice
-
T. Y. Nakagawa, W. H. Brissette, P. D. Lira et al. , "Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice, " Immunity, vol. 10, no. 2, pp. 207-217, 1999.
-
(1999)
Immunity
, vol.10
, Issue.2
, pp. 207-217
-
-
Nakagawa, T.Y.1
Brissette, W.H.2
Lira, P.D.3
-
60
-
-
0033083688
-
Cathepsin S required for normalMHC class II peptide loading and germinal center development
-
S. Guo-Ping, J. A. Villadangos, G. Dranoff et al. , "Cathepsin S required for normalMHC class II peptide loading and germinal center development, " Immunity, vol. 10, no. 2, pp. 197-206, 1999.
-
(1999)
Immunity
, vol.10
, Issue.2
, pp. 197-206
-
-
Guo-Ping, S.1
Villadangos, J.A.2
Dranoff, G.3
-
61
-
-
0033571691
-
Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells
-
C. Driessen, R. A. R. Bryant, A. M. Lennon-Duménil et al. , "Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells, " Journal of Cell Biology, vol. 147, no. 4, pp. 775-790, 1999.
-
(1999)
Journal of Cell Biology
, vol.147
, Issue.4
, pp. 775-790
-
-
Driessen, C.1
Bryant, R.A.R.2
Lennon-Duménil, A.M.3
-
62
-
-
84906993712
-
A novel allosteric mechanism in the cysteine peptidase cathepsin K discovered by computational methods
-
Article ID3287
-
M. Novinec, M. Korenc, A. Caflisch, R. Ranganathan, B. Lenarcic, and A. Baici, "A novel allosteric mechanism in the cysteine peptidase cathepsin K discovered by computational methods, " Nature Communications, vol. 5, Article ID3287, 2014.
-
(2014)
Nature Communications
, vol.5
-
-
Novinec, M.1
Korenc, M.2
Caflisch, A.3
Ranganathan, R.4
Lenarcic, B.5
Baici, A.6
-
63
-
-
12044253640
-
The refined 2. 15 å X-ray crystal structure of human liver cathepsin B: The structural basis for its specificity
-
D. Musil, D. Zucic, D. Turk et al. , "The refined 2. 15 å X-ray crystal structure of human liver cathepsin B: the structural basis for its specificity, " EMBO Journal, vol. 10, no. 9, pp. 2321-2330, 1991.
-
(1991)
EMBO Journal
, vol.10
, Issue.9
, pp. 2321-2330
-
-
Musil, D.1
Zucic, D.2
Turk, D.3
-
64
-
-
33749017931
-
Cysteine cathepsins: Multifunctional enzymes in cancer
-
M. M. Mohamed and B. F. Sloane, "Cysteine cathepsins: multifunctional enzymes in cancer, " Nature Reviews Cancer, vol. 6, no. 10, pp. 764-775, 2006.
-
(2006)
Nature Reviews Cancer
, vol.6
, Issue.10
, pp. 764-775
-
-
Mohamed, M.M.1
Sloane, B.F.2
-
65
-
-
19344374711
-
Cathepsin B in osteoarthritis: Uncontrolled proteolysis in the wrong place
-
A. Baici, A. Lang, R. Zwicky, and K. Müntener, "Cathepsin B in osteoarthritis: uncontrolled proteolysis in the wrong place, " Seminars in Arthritis and Rheumatism, vol. 34, no. 2, pp. 24-28, 2004.
-
(2004)
Seminars in Arthritis and Rheumatism
, vol.34
, Issue.2
, pp. 24-28
-
-
Baici, A.1
Lang, A.2
Zwicky, R.3
Müntener, K.4
-
66
-
-
17844362479
-
Caveolin-1 mediates the expression and localization of cathepsin B, pro-urokinase plasminogen activator and their cell-surface receptors in human colorectal carcinoma cells
-
D. Cavallo-Medved, J. Mai, J. Dosescu, M. Sameni, and B. F. Sloane, "Caveolin-1 mediates the expression and localization of cathepsin B, pro-urokinase plasminogen activator and their cell-surface receptors in human colorectal carcinoma cells, " Journal of Cell Science, vol. 118, no. 7, pp. 1493-1503, 2005.
-
(2005)
Journal of Cell Science
, vol.118
, Issue.7
, pp. 1493-1503
-
-
Cavallo-Medved, D.1
Mai, J.2
Dosescu, J.3
Sameni, M.4
Sloane, B.F.5
-
67
-
-
63049095880
-
Live-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation
-
D. Cavallo-Medved, D. Rudy, G. Blum, M. Bogyo, D. Caglic, and B. F. Sloane, "Live-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation, " Experimental Cell Research, vol. 315, no. 7, pp. 1234-1246, 2009.
-
(2009)
Experimental Cell Research
, vol.315
, Issue.7
, pp. 1234-1246
-
-
Cavallo-Medved, D.1
Rudy, D.2
Blum, G.3
Bogyo, M.4
Caglic, D.5
Sloane, B.F.6
-
68
-
-
0024604767
-
Degradation of laminin by human tumor cathepsin B
-
T. T. Lah, M. R. Buck, K. V. Honn et al. , "Degradation of laminin by human tumor cathepsin B, " Clinical and Experimental Metastasis, vol. 7, no. 4, pp. 461-468, 1989.
-
(1989)
Clinical and Experimental Metastasis
, vol.7
, Issue.4
, pp. 461-468
-
-
Lah, T.T.1
Buck, M.R.2
Honn, K.V.3
-
69
-
-
0026575258
-
Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues
-
M. R. Buck, D. G. Karustis, N. A. Day, K. V. Honn, and B. F. Sloane, "Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues, " Biochemical Journal, vol. 282, no. 1, pp. 273-278, 1992.
-
(1992)
Biochemical Journal
, vol.282
, Issue.1
, pp. 273-278
-
-
Buck, M.R.1
Karustis, D.G.2
Day, N.A.3
Honn, K.V.4
Sloane, B.F.5
-
70
-
-
26844559355
-
Inhibition of cathepsin B reduces beta-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: Evidence for cathepsin B as a candidate beta-secretase of Alzheimers disease
-
V. Hook, T. Toneff, M. Bogyo et al. , "Inhibition of cathepsin B reduces beta-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate beta-secretase of Alzheimers disease, " Biological Chemistry, vol. 386, no. 12, pp. 931-940, 2005.
-
(2005)
Biological Chemistry
, vol.386
, Issue.12
, pp. 931-940
-
-
Hook, V.1
Toneff, T.2
Bogyo, M.3
-
71
-
-
84873964654
-
Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein
-
C. Wang, B. Sun, Y. Zhou, A. Grubb, and L. Gan, "Cathepsin B degrades amyloid-β in mice expressing wild-type human amyloid precursor protein, "The Journal of Biological Chemistry, vol. 287, no. 47, pp. 39834-39841, 2012.
-
(2012)
The Journal of Biological Chemistry
, vol.287
, Issue.47
, pp. 39834-39841
-
-
Wang, C.1
Sun, B.2
Zhou, Y.3
Grubb, A.4
Gan, L.5
-
72
-
-
53849106834
-
Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimers disease
-
B. Sun, Y. Zhou, B. Halabisky et al. , "Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimers disease, " Neuron, vol. 60, no. 2, pp. 247-257, 2008.
-
(2008)
Neuron
, vol.60
, Issue.2
, pp. 247-257
-
-
Sun, B.1
Zhou, Y.2
Halabisky, B.3
-
73
-
-
78650818858
-
How does heparin prevent the pH inactivation of cathepsin B Allosteric mechanism elucidated by docking and molecular dynamics
-
article S5
-
M. G. S. Costa, P. R. Batista, C. S. Shida, C. H. Robert, P. M. Bisch, and P. G. Pascutti, "How does heparin prevent the pH inactivation of cathepsin B Allosteric mechanism elucidated by docking and molecular dynamics, " BMC Genomics, vol. 11, supplement 5, article S5, 2010.
-
(2010)
BMC Genomics
, vol.11
-
-
Costa, M.G.S.1
Batista, P.R.2
Shida, C.S.3
Robert, C.H.4
Bisch, P.M.5
Pascutti, P.G.6
-
74
-
-
84856286982
-
Substrate inhibition and allosteric regulation by heparan sulfate of Trypanosoma brucei cathepsin L
-
T. F. R. Costa, F. C. G. D. Reis, and A. P. C. A. Lima, "Substrate inhibition and allosteric regulation by heparan sulfate of Trypanosoma brucei cathepsin L, " Biochimica et Biophysica Acta, vol. 1824, no. 3, pp. 493-501, 2012.
-
(2012)
Biochimica et Biophysica Acta
, vol.1824
, Issue.3
, pp. 493-501
-
-
Costa, T.F.R.1
Reis, F.C.G.D.2
Lima, A.P.C.A.3
-
75
-
-
0037155252
-
Heparan sulfate modulates kinin release by Trypanosoma cruzi through the activity of cruzipain, "the
-
A. P. Lima, P. C. Almeida, I. L. Tersariol et al. , "Heparan sulfate modulates kinin release by Trypanosoma cruzi through the activity of cruzipain, "The Journal of Biological Chemistry, vol. 277, no. 8, pp. 5875-5881, 2002.
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.8
, pp. 5875-5881
-
-
Lima, A.P.1
Almeida, P.C.2
Tersariol, I.L.3
-
76
-
-
84894313105
-
Heparin modulates the endopeptidase activity of Leishmania mexicana cysteine protease cathepsin L-like rCPB2. 8
-
Article ID e80153
-
W. A. S. Judice, M. A. Manfredi, G. P. Souza et al. , "Heparin modulates the endopeptidase activity of Leishmania mexicana cysteine protease cathepsin L-like rCPB2. 8, " PLoS ONE, vol. 8, no. 11, Article ID e80153, 2013.
-
(2013)
PLoS ONE
, vol.8
, Issue.11
-
-
Judice, W.A.S.1
Manfredi, M.A.2
Souza, G.P.3
-
77
-
-
38749144762
-
The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K
-
J. Y. Gauthier, N. Chauret, W. Cromlish et al. , "The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K, " Bioorganic and Medicinal Chemistry Letters, vol. 18, no. 3, pp. 923-928, 2008.
-
(2008)
Bioorganic and Medicinal Chemistry Letters
, vol.18
, Issue.3
, pp. 923-928
-
-
Gauthier, J.Y.1
Chauret, N.2
Cromlish, W.3
-
78
-
-
84864568911
-
The future of osteoporosis treatment-A research update
-
Article IDw13624
-
K. Lippuner, "The future of osteoporosis treatment-a research update, " SwissMedicalWeekly, vol. 142, Article IDw13624, 2012.
-
(2012)
SwissMedicalWeekly
, vol.142
-
-
Lippuner, K.1
|