-
1
-
-
0030865104
-
Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents
-
O'Connor PM, Jackman J, Bae I, Myers TG, Fan S, Mutoh M, Scudiero DA, Monks A, Sausville EA et al (1997) Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents. Cancer Res 57: 4285-4300.
-
(1997)
Cancer Res
, vol.57
, pp. 4285-4300
-
-
O’Connor, P.M.1
Jackman, J.2
Bae, I.3
Myers, T.G.4
Fan, S.5
Mutoh, M.6
Scudiero, D.A.7
Monks, A.8
Sausville, E.A.9
-
2
-
-
0037047157
-
Apoptotic threshold is lowered by p53 transactivation of caspase-6
-
MacLachlan TK, El-Deiry WS (2002) Apoptotic threshold is lowered by p53 transactivation of caspase-6. Proc Natl Acad Sci U S A 99: 9492-9497.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 9492-9497
-
-
McLachlan, T.K.1
El-Deiry, W.S.2
-
3
-
-
85006263913
-
BID regulation by p53 contributes to chemosensitivity
-
Sax JK, Fei P, Murphy ME, Bernhard E, Korsmeyer SJ, El-Deiry WS (2002) BID regulation by p53 contributes to chemosensitivity. Nat Cell Biol 4: 842-849.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 842-849
-
-
Sax, J.K.1
Fei, P.2
Murphy, M.E.3
Bernhard, E.4
Korsmeyer, S.J.5
El-Deiry, W.S.6
-
4
-
-
18544364361
-
Physical interaction with human tumor-derived p53 mutants inhibits p63 activities
-
Strano S, Fontemaggi G, Costanzo A, Rizzo MG, Monti O, Baccarini A, Del Sal G, Levrero M, Sacchi A et al (2002) Physical interaction with human tumor-derived p53 mutants inhibits p63 activities. J Biol Chem 277: 18817-18826.
-
(2002)
J Biol Chem
, vol.277
, pp. 18817-18826
-
-
Strano, S.1
Fontemaggi, G.2
Costanzo, A.3
Rizzo, M.G.4
Monti, O.5
Baccarini, A.6
Del Sal, G.7
Levrero, M.8
Sacchi, A.9
-
5
-
-
0034703044
-
Physical and functional interaction between p53 mutants and different isoforms of p73
-
Strano S, Munarriz E, Rossi M, Cristofanelli B, Shaul Y, Castagnoli L, Levine AJ, Sacchi A, Cesareni G et al (2000) Physical and functional interaction between p53 mutants and different isoforms of p73. J Biol Chem 275: 29503-29512.
-
(2000)
J Biol Chem
, vol.275
, pp. 29503-29512
-
-
Strano, S.1
Munarriz, E.2
Rossi, M.3
Cristofanelli, B.4
Shaul, Y.5
Castagnoli, L.6
Levine, A.J.7
Sacchi, A.8
Cesareni, G.9
-
6
-
-
70349443284
-
When mutants gain new powers: News from the mutant p53 field
-
Brosh R, Rotter V (2009) When mutants gain new powers: news from the mutant p53 field. Nat Rev Cancer 9: 701-713.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 701-713
-
-
Brosh, R.1
Rotter, V.2
-
7
-
-
7344252500
-
Mutant p53 protein expression interferes with p53-independent apoptotic pathways
-
Li R, Sutphin PD, Schwartz D, Matas D, Almog N, Wolkowicz R, Goldfinger N, Pei H, Prokocimer M, Rotter V (1998) Mutant p53 protein expression interferes with p53-independent apoptotic pathways. Oncogene 16: 3269-3277.
-
(1998)
Oncogene
, vol.16
, pp. 3269-3277
-
-
Li, R.1
Sutphin, P.D.2
Schwartz, D.3
Matas, D.4
Almog, N.5
Wolkowicz, R.6
Goldfinger, N.7
Pei, H.8
Prokocimer, M.9
Rotter, V.10
-
8
-
-
0028171454
-
p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents
-
Fan S, el-Deiry WS, Bae I, Freeman J, Jondle D, Bhatia K, Fornace AJ Jr, Magrath I, Kohn KW, O'Connor PM (1994) p53 gene mutations are associated with decreased sensitivity of human lymphoma cells to DNA damaging agents. Cancer Res 54: 5824-5830.
-
(1994)
Cancer Res
, vol.54
, pp. 5824-5830
-
-
Fan, S.1
el-Deiry, W.S.2
Bae, I.3
Freeman, J.4
Jondle, D.5
Bhatia, K.6
Fornace, A.J.7
Magrath, I.8
Kohn, K.W.9
O’Connor, P.M.10
-
9
-
-
0033552948
-
Mutant p53 gain of function: Differential effects of different p53 mutants on resistance of cultured cells to chemotherapy
-
Blandino G, Levine AJ, Oren M (1999) Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy. Oncogene 18: 477-485.
-
(1999)
Oncogene
, vol.18
, pp. 477-485
-
-
Blandino, G.1
Levine, A.J.2
Oren, M.3
-
10
-
-
0033368192
-
De novo deletions of p53 gene and wild-type p53 correlate with acquired cisplatin-resistance in human osteosarcoma OST cell line
-
Asada N, Tsuchiya H, Tomita K (1999) De novo deletions of p53 gene and wild-type p53 correlate with acquired cisplatin-resistance in human osteosarcoma OST cell line. Anticancer Res 19: 5131-5137.
-
(1999)
Anticancer Res
, vol.19
, pp. 5131-5137
-
-
Asada, N.1
Tsuchiya, H.2
Tomita, K.3
-
11
-
-
0032749714
-
Modulation of cisplatinum cytotoxicity by p53: Effect of p53-mediated apoptosis and DNA repair
-
Fan J, Bertino JR (1999) Modulation of cisplatinum cytotoxicity by p53: effect of p53-mediated apoptosis and DNA repair. Mol Pharmacol 56: 966-972.
-
(1999)
Mol Pharmacol
, vol.56
, pp. 966-972
-
-
Fan, J.1
Bertino, J.R.2
-
12
-
-
0033572965
-
Accumulation of mutant p53(V143A) modulates the growth, clonogenicity, and radiochemosensitivity of malignant glioma cells independent of endogenous p53 status
-
Bartussek C, Naumann U, Weller M (1999) Accumulation of mutant p53(V143A) modulates the growth, clonogenicity, and radiochemosensitivity of malignant glioma cells independent of endogenous p53 status. Exp Cell Res 253: 432-439.
-
(1999)
Exp Cell Res
, vol.253
, pp. 432-439
-
-
Bartussek, C.1
Naumann, U.2
Weller, M.3
-
13
-
-
0034978219
-
Various forms of mutant p53 confer sensitivity to cisplatin and doxorubicin in bladder cancer cells
-
Chang FL, Lai MD (2001) Various forms of mutant p53 confer sensitivity to cisplatin and doxorubicin in bladder cancer cells. J Urol 166: 304-310.
-
(2001)
J Urol
, vol.166
, pp. 304-310
-
-
Chang, F.L.1
Lai, M.D.2
-
14
-
-
0034086197
-
p53 alterations predict tumor response to neoadjuvant chemotherapy in head and neck squamous cell carcinoma: A prospective series
-
Cabelguenne A, Blons H, de Waziers I, Carnot F, Houllier AM, Soussi T, Brasnu D, Beaune P, Laccourreye O, Laurent-Puig P (2000) p53 alterations predict tumor response to neoadjuvant chemotherapy in head and neck squamous cell carcinoma: a prospective series. J Clin Oncol 18: 1465-1473.
-
(2000)
J Clin Oncol
, vol.18
, pp. 1465-1473
-
-
Cabelguenne, A.1
Blons, H.2
de Waziers, I.3
Carnot, F.4
Houllier, A.M.5
Soussi, T.6
Brasnu, D.7
Beaune, P.8
Laccourreye, O.9
Laurent-Puig, P.10
-
15
-
-
10344250962
-
p53 mutation and locoregional treatment failure in head and neck squamous cell carcinoma
-
Koch WM, Brennan JA, Zahurak M, Goodman SN, Westra WH, Schwab D, Yoo GH, Lee DJ, Forastiere AA, Sidransky D (1996) p53 mutation and locoregional treatment failure in head and neck squamous cell carcinoma. J Natl Cancer Inst 88: 1580-1586.
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 1580-1586
-
-
Koch, W.M.1
Brennan, J.A.2
Zahurak, M.3
Goodman, S.N.4
Westra, W.H.5
Schwab, D.6
Yoo, G.H.7
Lee, D.J.8
Forastiere, A.A.9
Sidransky, D.10
-
16
-
-
0028901034
-
Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline
-
Fan S, Smith ML, Rivet DJ 2nd, Duba D, Zhan Q, Kohn KW, Fornace AJ Jr, O'Connor PM (1995) Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline. Cancer Res 55: 1649-1654.
-
(1995)
Cancer Res
, vol.55
, pp. 1649-1654
-
-
Fan, S.1
Smith, M.L.2
Rivet, D.J.3
Duba, D.4
Zhan, Q.5
Kohn, K.W.6
Fornace, A.J.7
O’Connor, P.M.8
-
17
-
-
0041342137
-
P53 mutation correlates with cisplatin sensitivity in head and neck squamous cell carcinoma lines
-
Bradford CR, Zhu S, Ogawa H, Ogawa T, Ubell M, Narayan A, Johnson G, Wolf GT, Fisher SG, Carey TE (2003) P53 mutation correlates with cisplatin sensitivity in head and neck squamous cell carcinoma lines. Head Neck 25: 654-661.
-
(2003)
Head Neck
, vol.25
, pp. 654-661
-
-
Bradford, C.R.1
Zhu, S.2
Ogawa, H.3
Ogawa, T.4
Ubell, M.5
Narayan, A.6
Johnson, G.7
Wolf, G.T.8
Fisher, S.G.9
Carey, T.E.10
-
18
-
-
84862124987
-
p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer
-
Jackson JG, Pant V, Li Q, Chang LL, Quintas-Cardama A, Garza D, Tavana O, Yang P, Manshouri T et al (2013) p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer. Cancer Cell 21: 793-806.
-
(2013)
Cancer Cell
, vol.21
, pp. 793-806
-
-
Jackson, J.G.1
Pant, V.2
Li, Q.3
Chang, L.L.4
Quintas-Cardama, A.5
Garza, D.6
Tavana, O.7
Yang, P.8
Manshouri, T.9
-
19
-
-
84857989986
-
Resistance and gain-of-resistance phenotypes in cancers harboring wild-type p53
-
Martinez-Rivera M, Siddik ZH (2012) Resistance and gain-of-resistance phenotypes in cancers harboring wild-type p53. Biochem Pharmacol 83: 1049-1062.
-
(2012)
Biochem Pharmacol
, vol.83
, pp. 1049-1062
-
-
Martinez-Rivera, M.1
Siddik, Z.H.2
-
20
-
-
0038021147
-
Resistance to DNA-damaging agents is discordant from experimental metastatic capacity in MEF rastransformants-expressing gain of function MTp53
-
Bristow RG, Peacock J, Jang A, Kim J, Hill RP, Benchimol S (2003) Resistance to DNA-damaging agents is discordant from experimental metastatic capacity in MEF rastransformants-expressing gain of function MTp53. Oncogene 22: 2960-2966.
-
(2003)
Oncogene
, vol.22
, pp. 2960-2966
-
-
Bristow, R.G.1
Peacock, J.2
Jang, A.3
Kim, J.4
Hill, R.P.5
Benchimol, S.6
-
21
-
-
27644529786
-
Tumor-derived p53 mutants induce NF-kappaB2 gene expression
-
Scian MJ, Stagliano KE, Anderson MA, Hassan S, Bowman M, Miles MF, Deb SP, Deb S (2005) Tumor-derived p53 mutants induce NF-kappaB2 gene expression. Mol Cell Biol 25: 10097-10110.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 10097-10110
-
-
Scian, M.J.1
Stagliano, K.E.2
Anderson, M.A.3
Hassan, S.4
Bowman, M.5
Miles, M.F.6
Deb, S.P.7
Deb, S.8
-
22
-
-
34247899190
-
Cancer-derived p53 mutants suppress p53-target gene expression-potential mechanism for gain of function of mutant p53
-
Vikhanskaya F, Lee MK, Mazzoletti M, Broggini M, Sabapathy K (2007) Cancer-derived p53 mutants suppress p53-target gene expression-potential mechanism for gain of function of mutant p53. Nucleic Acids Res 35: 2093-2104.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 2093-2104
-
-
Vikhanskaya, F.1
Lee, M.K.2
Mazzoletti, M.3
Broggini, M.4
Sabapathy, K.5
-
23
-
-
34147172345
-
p53-R273H gains new function in induction of drug resistance through down-regulation of procaspase-3
-
Wong RP, Tsang WP, Chau PY, Co NN, Tsang TY, Kwok TT (2007) p53-R273H gains new function in induction of drug resistance through down-regulation of procaspase-3. Mol Cancer Ther 6: 1054-1061.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1054-1061
-
-
Wong, R.P.1
Tsang, W.P.2
Chau, P.Y.3
Co, N.N.4
Tsang, T.Y.5
Kwok, T.T.6
-
24
-
-
30544452870
-
Mutant p53 gain of function: Reduction of tumor malignancy of human cancer cell lines through abrogation of mutant p53 expression
-
Bossi G, Lapi E, Strano S, Rinaldo C, Blandino G, Sacchi A (2006) Mutant p53 gain of function: reduction of tumor malignancy of human cancer cell lines through abrogation of mutant p53 expression. Oncogene 25: 304-309.
-
(2006)
Oncogene
, vol.25
, pp. 304-309
-
-
Bossi, G.1
Lapi, E.2
Strano, S.3
Rinaldo, C.4
Blandino, G.5
Sacchi, A.6
-
25
-
-
0030232710
-
The p53 gene as a modifier of intrinsic radiosensitivity: Implications for radiotherapy
-
Bristow RG, Benchimol S, Hill RP (1996) The p53 gene as a modifier of intrinsic radiosensitivity: implications for radiotherapy. Radiother Oncol 40: 197-223.
-
(1996)
Radiother Oncol
, vol.40
, pp. 197-223
-
-
Bristow, R.G.1
Benchimol, S.2
Hill, R.P.3
-
26
-
-
0345256634
-
The role of p53 in chemosensitivity and radiosensitivity
-
El-Deiry WS (2003) The role of p53 in chemosensitivity and radiosensitivity. Oncogene 22: 7486-7495.
-
(2003)
Oncogene
, vol.22
, pp. 7486-7495
-
-
El-Deiry, W.S.1
-
27
-
-
0034093941
-
p53: Biology and role for cellular radiosensitivity
-
Dahm-Daphi J (2000) p53: biology and role for cellular radiosensitivity. Strahlenther Onkol 176: 278-285.
-
(2000)
Strahlenther Onkol
, vol.176
, pp. 278-285
-
-
Dahm-Daphi, J.1
-
28
-
-
0027285380
-
p53 mutations increase resistance to ionizing radiation
-
Lee JM, Bernstein A (1993) p53 mutations increase resistance to ionizing radiation. Proc Natl Acad Sci U S A 90: 5742-5746.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 5742-5746
-
-
Lee, J.M.1
Bernstein, A.2
-
29
-
-
0032499298
-
Radioresistant MTp53-expressing rat embryo cell transformants exhibit increased DNA-dsb rejoining during exposure to ionizing radiation
-
Bristow RG, Hu Q, Jang A, Chung S, Peacock J, Benchimol S, Hill R (1998) Radioresistant MTp53-expressing rat embryo cell transformants exhibit increased DNA-dsb rejoining during exposure to ionizing radiation. Oncogene 16: 1789-1802.
-
(1998)
Oncogene
, vol.16
, pp. 1789-1802
-
-
Bristow, R.G.1
Hu, Q.2
Jang, A.3
Chung, S.4
Peacock, J.5
Benchimol, S.6
Hill, R.7
-
30
-
-
55749115264
-
Variations in sensitivity to ionizing radiation in relation to p53 mutation point
-
Okaichi K, Ide-Kanematsu M, Izumi N, Morita N, Okumura Y, Ihara M (2008) Variations in sensitivity to ionizing radiation in relation to p53 mutation point. Anticancer Res 28: 2687-2690.
-
(2008)
Anticancer Res
, vol.28
, pp. 2687-2690
-
-
Okaichi, K.1
Ide-Kanematsu, M.2
Izumi, N.3
Morita, N.4
Okumura, Y.5
Ihara, M.6
-
31
-
-
41749102683
-
A quantitative overview of radiosensitivity of human tumor cells across histological type and TP53 status
-
Williams JR, Zhang Y, Zhou H, Gridley DS, Koch CJ, Russell J, Slater JS, Little JB (2008) A quantitative overview of radiosensitivity of human tumor cells across histological type and TP53 status. Int J Radiat Biol 84: 253-264.
-
(2008)
Int J Radiat Biol
, vol.84
, pp. 253-264
-
-
Williams, J.R.1
Zhang, Y.2
Zhou, H.3
Gridley, D.S.4
Koch, C.J.5
Russell, J.6
Slater, J.S.7
Little, J.B.8
-
32
-
-
84855443905
-
TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence
-
Skinner HD, Sandulache VC, Ow TJ, Meyn RE, Yordy JS, Beadle BM, Fitzgerald AL, Giri U, Ang KK, Myers JN (2012) TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence. Clin Cancer Res 18: 290-300.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 290-300
-
-
Skinner, H.D.1
Sandulache, V.C.2
Ow, T.J.3
Meyn, R.E.4
Yordy, J.S.5
Beadle, B.M.6
Fitzgerald, A.L.7
Giri, U.8
Ang, K.K.9
Myers, J.N.10
-
33
-
-
84856223010
-
Individualizing antimetabolic treatment strategies for head and neck squamous cell carcinoma based on TP53 mutational status
-
Sandulache VC, Skinner HD, Ow TJ, Zhang A, Xia X, Luchak JM, Wong LJ, Pickering CR, Zhou G, Myers JN (2012) Individualizing antimetabolic treatment strategies for head and neck squamous cell carcinoma based on TP53 mutational status. Cancer 118: 711-721.
-
(2012)
Cancer
, vol.118
, pp. 711-721
-
-
Sandulache, V.C.1
Skinner, H.D.2
Ow, T.J.3
Zhang, A.4
Xia, X.5
Luchak, J.M.6
Wong, L.J.7
Pickering, C.R.8
Zhou, G.9
Myers, J.N.10
-
34
-
-
44849106090
-
Induction of genetic instability by gain-of-function p53 cancer mutants
-
Xu Y (2008) Induction of genetic instability by gain-of-function p53 cancer mutants. Oncogene 27: 3501-3507.
-
(2008)
Oncogene
, vol.27
, pp. 3501-3507
-
-
Xu, Y.1
-
35
-
-
84874735362
-
The tumor suppressor, p53, contributes to radiosensitivity of lung cancer cells by regulating autophagy and apoptosis
-
Cheng G, Kong D, Hou X, Liang B, He M, Liang N, Ma S, Liu X (2013) The tumor suppressor, p53, contributes to radiosensitivity of lung cancer cells by regulating autophagy and apoptosis. Cancer Biother Radiopharm 28: 153-159.
-
(2013)
Cancer Biother Radiopharm
, vol.28
, pp. 153-159
-
-
Cheng, G.1
Kong, D.2
Hou, X.3
Liang, B.4
He, M.5
Liang, N.6
Ma, S.7
Liu, X.8
-
36
-
-
22744458985
-
Transcriptional activities of mutant p53: When mutations are more than a loss
-
Kim E, Deppert W (2004) Transcriptional activities of mutant p53: when mutations are more than a loss. J Cell Biochem 93: 878-886.
-
(2004)
J Cell Biochem
, vol.93
, pp. 878-886
-
-
Kim, E.1
Deppert, W.2
-
37
-
-
5644225629
-
Modulation of gene expression by tumor-derived p53 mutants
-
Scian MJ, Stagliano KE, Ellis MA, Hassan S, Bowman M, Miles MF, Deb SP, Deb S (2004) Modulation of gene expression by tumor-derived p53 mutants. Cancer Res 64: 7447-7454.
-
(2004)
Cancer Res
, vol.64
, pp. 7447-7454
-
-
Scian, M.J.1
Stagliano, K.E.2
Ellis, M.A.3
Hassan, S.4
Bowman, M.5
Miles, M.F.6
Deb, S.P.7
Deb, S.8
-
38
-
-
84856117319
-
p53 mutants induce transcription of NF-kappaB2 in H1299 cells through CBP and STAT binding on the NF-kappaB2 promoter and gain of function activity
-
Vaughan CA, Singh S, Windle B, Sankala HM, Graves PR, Andrew Yeudall W, Deb SP, Deb S (2012) p53 mutants induce transcription of NF-kappaB2 in H1299 cells through CBP and STAT binding on the NF-kappaB2 promoter and gain of function activity. Arch Biochem Biophys 518: 79-88.
-
(2012)
Arch Biochem Biophys
, vol.518
, pp. 79-88
-
-
Vaughan, C.A.1
Singh, S.2
Windle, B.3
Sankala, H.M.4
Graves, P.R.5
Andrew Yeudall, W.6
Deb, S.P.7
Deb, S.8
-
39
-
-
0035914335
-
Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1
-
Sampath J, Sun D, Kidd VJ, Grenet J, Gandhi A, Shapiro LH, Wang Q, Zambetti GP, Schuetz JD (2001) Mutant p53 cooperates with ETS and selectively up-regulates human MDR1 not MRP1. J Biol Chem 276: 39359-39367.
-
(2001)
J Biol Chem
, vol.276
, pp. 39359-39367
-
-
Sampath, J.1
Sun, D.2
Kidd, V.J.3
Grenet, J.4
Gandhi, A.5
Shapiro, L.H.6
Wang, Q.7
Zambetti, G.P.8
Schuetz, J.D.9
-
40
-
-
34047205431
-
Mutant p53: An oncogenic transcription factor
-
Strano S, Dell'Orso S, Di Agostino S, Fontemaggi G, Sacchi A, Blandino G (2007) Mutant p53: an oncogenic transcription factor. Oncogene 26: 2212-2219.
-
(2007)
Oncogene
, vol.26
, pp. 2212-2219
-
-
Strano, S.1
Dell’Orso, S.2
Di Agostino, S.3
Fontemaggi, G.4
Sacchi, A.5
Blandino, G.6
-
41
-
-
79959840762
-
Upregulation of the mitochondrial transport protein, Tim50, by mutant p53 contributes to cell growth and chemoresistance
-
Sankala H, Vaughan C, Wang J, Deb S, Graves PR (2011) Upregulation of the mitochondrial transport protein, Tim50, by mutant p53 contributes to cell growth and chemoresistance. Arch Biochem Biophys 512: 52-60.
-
(2011)
Arch Biochem Biophys
, vol.512
, pp. 52-60
-
-
Sankala, H.1
Vaughan, C.2
Wang, J.3
Deb, S.4
Graves, P.R.5
-
42
-
-
0029619819
-
The MDR1 downstream promoter contains sequence-specific binding sites for wild-type p53
-
Strauss BE, Shivakumar C, Deb SP, Deb S, Haas M (1995) The MDR1 downstream promoter contains sequence-specific binding sites for wild-type p53. Biochem Biophys Res Commun 217: 825-831.
-
(1995)
Biochem Biophys Res Commun
, vol.217
, pp. 825-831
-
-
Strauss, B.E.1
Shivakumar, C.2
Deb, S.P.3
Deb, S.4
Haas, M.5
-
43
-
-
84055190665
-
Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop
-
Valenti F, Fausti F, Biagioni F, Shay T, Fontemaggi G, Domany E, Yaffe MB, Strano S, Blandino G, Di Agostino S (2011) Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop. Cell Cycle 10: 4330-4340.
-
(2011)
Cell Cycle
, vol.10
, pp. 4330-4340
-
-
Valenti, F.1
Fausti, F.2
Biagioni, F.3
Shay, T.4
Fontemaggi, G.5
Domany, E.6
Yaffe, M.B.7
Strano, S.8
Blandino, G.9
Di Agostino, S.10
-
44
-
-
84875509079
-
Gain-of-function activity of mutant p53 in lung cancer through up-regulation of receptor protein tyrosine kinase Axl
-
Vaughan CA, Singh S, Windle B, Yeudall WA, Frum R, Grossman SR, Deb SP, Deb S (2012) Gain-of-function activity of mutant p53 in lung cancer through up-regulation of receptor protein tyrosine kinase Axl. Genes Cancer 3: 491-502.
-
(2012)
Genes Cancer
, vol.3
, pp. 491-502
-
-
Vaughan, C.A.1
Singh, S.2
Windle, B.3
Yeudall, W.A.4
Frum, R.5
Grossman, S.R.6
Deb, S.P.7
Deb, S.8
-
45
-
-
84897080056
-
Gain-of-function mutant p53 downregulates miR-223 contributing to chemoresistance of cultured tumor cells
-
Masciarelli S, Fontemaggi G, Di Agostino S, Donzelli S, Carcarino E, Strano S, Blandino G (2013) Gain-of-function mutant p53 downregulates miR-223 contributing to chemoresistance of cultured tumor cells. Oncogene 32: 1-8.
-
(2013)
Oncogene
, vol.32
, pp. 1-8
-
-
Masciarelli, S.1
Fontemaggi, G.2
Di Agostino, S.3
Donzelli, S.4
Carcarino, E.5
Strano, S.6
Blandino, G.7
-
46
-
-
0033549844
-
Cloning and characterization of the human BAG-1 gene promoter: Upregulation by tumor-derived p53 mutants
-
Yang X, Pater A, Tang SC (1999) Cloning and characterization of the human BAG-1 gene promoter: upregulation by tumor-derived p53 mutants. Oncogene 18: 4546-4553.
-
(1999)
Oncogene
, vol.18
, pp. 4546-4553
-
-
Yang, X.1
Pater, A.2
Tang, S.C.3
-
47
-
-
0042337367
-
Mutant p53 gain of function: Repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants
-
Zalcenstein A, Stambolsky P, Weisz L, Muller M, Wallach D, Goncharov TM, Krammer PH, Rotter V, Oren M (2003) Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants. Oncogene 22: 5667-5676.
-
(2003)
Oncogene
, vol.22
, pp. 5667-5676
-
-
Zalcenstein, A.1
Stambolsky, P.2
Weisz, L.3
Muller, M.4
Wallach, D.5
Goncharov, T.M.6
Krammer, P.H.7
Rotter, V.8
Oren, M.9
-
48
-
-
30944461587
-
Repression of the MSP/MST-1 gene contributes to the antiapoptotic gain of function of mutant p53
-
Zalcenstein A, Weisz L, Stambolsky P, Bar J, Rotter V, Oren M (2006) Repression of the MSP/MST-1 gene contributes to the antiapoptotic gain of function of mutant p53. Oncogene 25: 359-369.
-
(2006)
Oncogene
, vol.25
, pp. 359-369
-
-
Zalcenstein, A.1
Weisz, L.2
Stambolsky, P.3
Bar, J.4
Rotter, V.5
Oren, M.6
-
49
-
-
84871869428
-
Identification of novel mutant p53 interacting proteins by proteomic analysis
-
Deb S, Graves PR (2013) Identification of novel mutant p53 interacting proteins by proteomic analysis. Methods Mol Biol 962: 85-94.
-
(2013)
Methods Mol Biol
, vol.962
, pp. 85-94
-
-
Deb, S.1
Graves, P.R.2
-
50
-
-
84871892027
-
Measurement of chemosensitivity and growth rate in p53 expressing cells
-
Ramamoorthy M, Vaughan C, Deb S, Deb SP (2012) Measurement of chemosensitivity and growth rate in p53 expressing cells. Methods Mol Biol 962: 127-133.
-
(2012)
Methods Mol Biol
, vol.962
, pp. 127-133
-
-
Ramamoorthy, M.1
Vaughan, C.2
Deb, S.3
Deb, S.P.4
-
51
-
-
15244362062
-
P53 abnormalities and outcomes in colorectal cancer: A systematic review
-
Munro AJ, Lain S, Lane DP (2005) P53 abnormalities and outcomes in colorectal cancer: a systematic review. Br J Cancer 92: 434-444.
-
(2005)
Br J Cancer
, vol.92
, pp. 434-444
-
-
Munro, A.J.1
Lain, S.2
Lane, D.P.3
-
52
-
-
0142087616
-
Prognostic significance of p53 mutation and p53 overexpression in advanced epithelial ovarian cancer: A Gynecologic Oncology Group Study
-
Havrilesky L, Darcy kM, Hamdan H, Priore RL, Leon J, Bell J, Berchuck A (2003) Prognostic significance of p53 mutation and p53 overexpression in advanced epithelial ovarian cancer: a Gynecologic Oncology Group Study. J Clin Oncol 21: 3814-3825.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3814-3825
-
-
Havrilesky, L.1
Darcy k, M.2
Hamdan, H.3
Priore, R.L.4
Leon, J.5
Bell, J.6
Berchuck, A.7
-
53
-
-
13344249778
-
A comparative study of p53 gene mutations, protein accumulation, and response to cisplatin-based chemotherapy in advanced ovarian carcinoma
-
Righetti SC, Della Torre G, Pilotti S, Menard S, Ottone F, Colnaghi MI, Pierotti MA, Lavarino C, Cornarotti M et al (1996) A comparative study of p53 gene mutations, protein accumulation, and response to cisplatin-based chemotherapy in advanced ovarian carcinoma. Cancer Res 56: 689-693.
-
(1996)
Cancer Res
, vol.56
, pp. 689-693
-
-
Righetti, S.C.1
Della Torre, G.2
Pilotti, S.3
Menard, S.4
Ottone, F.5
Colnaghi, M.I.6
Pierotti, M.A.7
Lavarino, C.8
Cornarotti, M.9
-
54
-
-
8044233696
-
p53 alterations are predictive of chemoresistance and aggressiveness in ovarian carcinomas: A molecular and immunohistochemical study
-
Buttitta F, Marchetti A, Gadducci A, Pellegrini S, Morganti M, Carnicelli V, Cosio S, Gagetti O, Genazzani AR, Bevilacqua G (1997) p53 alterations are predictive of chemoresistance and aggressiveness in ovarian carcinomas: a molecular and immunohistochemical study. Br J Cancer 75: 230-235.
-
(1997)
Br J Cancer
, vol.75
, pp. 230-235
-
-
Buttitta, F.1
Marchetti, A.2
Gadducci, A.3
Pellegrini, S.4
Morganti, M.5
Carnicelli, V.6
Cosio, S.7
Gagetti, O.8
Genazzani, A.R.9
Bevilacqua, G.10
-
55
-
-
0034796867
-
Correlation of p53 mutations with resistance to platinum-based chemotherapy and shortened survival in ovarian cancer
-
Reles A, Wen WH, Schmider A, Gee C, Runnebaum IB, Kilian U, Jones LA, El-Naggar A, Minguillon C et al (2001) Correlation of p53 mutations with resistance to platinum-based chemotherapy and shortened survival in ovarian cancer. Clin Cancer Res 7: 2984-2997.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 2984-2997
-
-
Reles, A.1
Wen, W.H.2
Schmider, A.3
Gee, C.4
Runnebaum, I.B.5
Kilian, U.6
Jones, L.A.7
El-Naggar, A.8
Minguillon, C.9
-
56
-
-
0033041769
-
Carboplatin and paclitaxel, alone and in combination: Dose escalation, measurement of renal function, and role of the p53 tumor suppressor gene
-
Calvert AH, Ghokul S, Al-Azraqi A, Wright J, Lind M, Bailey N, Highley M, Siddiqui N, Lunec J et al (1999) Carboplatin and paclitaxel, alone and in combination: dose escalation, measurement of renal function, and role of the p53 tumor suppressor gene. Semin Oncol 26: 90-94.
-
(1999)
Semin Oncol
, vol.26
, pp. 90-94
-
-
Calvert, A.H.1
Ghokul, S.2
Al-Azraqi, A.3
Wright, J.4
Lind, M.5
Bailey, N.6
Highley, M.7
Siddiqui, N.8
Lunec, J.9
-
57
-
-
0035462780
-
p53 gene status and chemosensitivity in ovarian cancer
-
Kigawa J, Sato S, Shimada M, Takahashi M, Itamochi H, Kanamori Y, Terakawa N (2001) p53 gene status and chemosensitivity in ovarian cancer. Hum Cell 14: 165-171.
-
(2001)
Hum Cell
, vol.14
, pp. 165-171
-
-
Kigawa, J.1
Sato, S.2
Shimada, M.3
Takahashi, M.4
Itamochi, H.5
Kanamori, Y.6
Terakawa, N.7
-
58
-
-
71449108641
-
The role of p53 as a surrogate marker for chemotherapeutical responsiveness in ovarian cancer
-
Bauerschlag DO, Schem C, Weigel MT, Von Kaisenberg C, Strauss A, Bauknecht T, Maass N, Meinhold-Heerlein I (2010) The role of p53 as a surrogate marker for chemotherapeutical responsiveness in ovarian cancer. J Cancer Res Clin Oncol 136: 79-88.
-
(2010)
J Cancer Res Clin Oncol
, vol.136
, pp. 79-88
-
-
Bauerschlag, D.O.1
Schem, C.2
Weigel, M.T.3
Von Kaisenberg, C.4
Strauss, A.5
Bauknecht, T.6
Maass, N.7
Meinhold-Heerlein, I.8
-
59
-
-
0034551724
-
p53 gene status and response to platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma
-
Lavarino C, Pilotti S, Oggionni M, Gatti L, Perego P, Bresciani G, Pierotti MA, Scambia G, Ferrandina G et al (2000) p53 gene status and response to platinum/paclitaxel-based chemotherapy in advanced ovarian carcinoma. J Clin Oncol 18: 3936-3945.
-
(2000)
J Clin Oncol
, vol.18
, pp. 3936-3945
-
-
Lavarino, C.1
Pilotti, S.2
Oggionni, M.3
Gatti, L.4
Perego, P.5
Bresciani, G.6
Pierotti, M.A.7
Scambia, G.8
Ferrandina, G.9
-
60
-
-
84856392090
-
Molecular predictive factors of outcome of radiotherapy in cervical cancer
-
Petera J, Sirak I, Beranek M, Vosmik M, Drastikova M, Paulikova S, Soumarova R (2012) Molecular predictive factors of outcome of radiotherapy in cervical cancer. Neoplasma 58: 469-475.
-
(2012)
Neoplasma
, vol.58
, pp. 469-475
-
-
Petera, J.1
Sirak, I.2
Beranek, M.3
Vosmik, M.4
Drastikova, M.5
Paulikova, S.6
Soumarova, R.7
-
61
-
-
0035160889
-
The effects of p53 status and human papillomavirus infection on the clinical outcome of patients with stage IIIB cervical carcinoma treated with radiation therapy alone
-
Ishikawa H, Mitsuhashi N, Sakurai H, Maebayashi K, Niibe H (2001) The effects of p53 status and human papillomavirus infection on the clinical outcome of patients with stage IIIB cervical carcinoma treated with radiation therapy alone. Cancer 91: 80-89.
-
(2001)
Cancer
, vol.91
, pp. 80-89
-
-
Ishikawa, H.1
Mitsuhashi, N.2
Sakurai, H.3
Maebayashi, K.4
Niibe, H.5
-
62
-
-
17744403009
-
Complete sequencing of TP53 predicts poor response to systemic therapy of advanced breast cancer
-
Berns EM, Foekens JA, Vossen R, Look MP, Devilee P, Henzen-Logmans SC, van Staveren IL, van Putten WL, Inganas M et al (2000) Complete sequencing of TP53 predicts poor response to systemic therapy of advanced breast cancer. Cancer Res 60: 2155-2162.
-
(2000)
Cancer Res
, vol.60
, pp. 2155-2162
-
-
Berns, E.M.1
Foekens, J.A.2
Vossen, R.3
Look, M.P.4
Devilee, P.5
Henzen-Logmans, S.C.6
van Staveren, I.L.7
van Putten, W.L.8
Inganas, M.9
-
63
-
-
84863102966
-
Value of TP53 status for predicting response to neoadjuvant chemotherapy in breast cancer: A meta-analysis
-
Chen MB, Zhu YQ, Xu JY, Wang LQ, Liu CY, Ji ZY, Lu PH (2012) Value of TP53 status for predicting response to neoadjuvant chemotherapy in breast cancer: a meta-analysis. PLoS One 7: e39655.
-
(2012)
PLoS One
, vol.7
-
-
Chen, M.B.1
Zhu, Y.Q.2
Xu, J.Y.3
Wang, L.Q.4
Liu, C.Y.5
Ji, Z.Y.6
Lu, P.H.7
-
64
-
-
0033971806
-
TP53 mutation and p53 overexpression for prediction of response to neoadjuvant treatment in breast cancer patients
-
Kandioler-Eckersberger D, Ludwig C, Rudas M, Kappel S, Janschek E, Wenzel C, Schlagbauer-Wadl H, Mittlbock M, Gnant M et al (2000) TP53 mutation and p53 overexpression for prediction of response to neoadjuvant treatment in breast cancer patients. Clin Cancer Res 6: 50-56.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 50-56
-
-
Kandioler-Eckersberger, D.1
Ludwig, C.2
Rudas, M.3
Kappel, S.4
Janschek, E.5
Wenzel, C.6
Schlagbauer-Wadl, H.7
Mittlbock, M.8
Gnant, M.9
-
65
-
-
79957645965
-
Gene expression signature of TP53 but not its mutation status predicts response to sequential paclitaxel and 5-FU/epirubicin/cyclophosphamide in human breast cancer
-
Oshima K, Naoi Y, Kishi K, Nakamura Y, Iwamoto T, Shimazu K, Nakayama T, Kim SJ, Baba Y et al (2011) Gene expression signature of TP53 but not its mutation status predicts response to sequential paclitaxel and 5-FU/epirubicin/cyclophosphamide in human breast cancer. Cancer Lett 307: 149-157.
-
(2011)
Cancer Lett
, vol.307
, pp. 149-157
-
-
Oshima, K.1
Naoi, Y.2
Kishi, K.3
Nakamura, Y.4
Iwamoto, T.5
Shimazu, K.6
Nakayama, T.7
Kim, S.J.8
Baba, Y.9
-
66
-
-
0035866772
-
Influence of TP53 gene alterations and c-erbB-2 expression on the response to treatment with doxorubicin in locally advanced breast cancer
-
Geisler S, Lonning PE, Aas T, Johnsen H, Fluge O, Haugen DF, Lillehaug JR, Akslen LA, Borresen-Dale AL (2001) Influence of TP53 gene alterations and c-erbB-2 expression on the response to treatment with doxorubicin in locally advanced breast cancer. Cancer Res 61: 2505-2512.
-
(2001)
Cancer Res
, vol.61
, pp. 2505-2512
-
-
Geisler, S.1
Lonning, P.E.2
Aas, T.3
Johnsen, H.4
Fluge, O.5
Haugen, D.F.6
Lillehaug, J.R.7
Akslen, L.A.8
Borresen-Dale, A.L.9
-
67
-
-
0028875410
-
Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy
-
Bergh J, Norberg T, Sjogren S, Lindgren A, Holmberg L (1995) Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy. Nat Med 1: 1029-1034.
-
(1995)
Nat Med
, vol.1
, pp. 1029-1034
-
-
Bergh, J.1
Norberg, T.2
Sjogren, S.3
Lindgren, A.4
Holmberg, L.5
-
68
-
-
0029956081
-
Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients
-
Aas T, Borresen AL, Geisler S, Smith-Sorensen B, Johnsen H, Varhaug JE, Akslen LA, Lonning PE (1996) Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients. Nat Med 2: 811-814.
-
(1996)
Nat Med
, vol.2
, pp. 811-814
-
-
Aas, T.1
Borresen, A.L.2
Geisler, S.3
Smith-Sorensen, B.4
Johnsen, H.5
Varhaug, J.E.6
Akslen, L.A.7
Lonning, P.E.8
-
69
-
-
0028176804
-
p53 mutations and overexpression in locally advanced breast cancers
-
Faille A, De Cremoux P, Extra JM, Linares G, Espie M, Bourstyn E, De Rocquancourt A, Giacchetti S, Marty M, Calvo F (1994) p53 mutations and overexpression in locally advanced breast cancers. Br J Cancer 69: 1145-1150.
-
(1994)
Br J Cancer
, vol.69
, pp. 1145-1150
-
-
Faille, A.1
De Cremoux, P.2
Extra, J.M.3
Linares, G.4
Espie, M.5
Bourstyn, E.6
De Rocquancourt, A.7
Giacchetti, S.8
Marty, M.9
Calvo, F.10
-
70
-
-
0028859453
-
p53 status predicts survival in breast cancer patients treated with or without postoperative radiotherapy: A novel hypothesis based on clinical findings
-
Jansson T, Inganas M, Sjogren S, Norberg T, Lindgren A, Holmberg L, Bergh J (1995) p53 status predicts survival in breast cancer patients treated with or without postoperative radiotherapy: a novel hypothesis based on clinical findings. J Clin Oncol 13: 2745-2751.
-
(1995)
J Clin Oncol
, vol.13
, pp. 2745-2751
-
-
Jansson, T.1
Inganas, M.2
Sjogren, S.3
Norberg, T.4
Lindgren, A.5
Holmberg, L.6
Bergh, J.7
-
71
-
-
0027524636
-
The incidence of p53 mutations increases with progression of head and neck cancer
-
Boyle JO, Hakim J, Koch W, van der Riet P, Hruban RH, Roa RA, Correo R, Eby YJ, Ruppert JM, Sidransky D (1993) The incidence of p53 mutations increases with progression of head and neck cancer. Cancer Res 53: 4477-4480.
-
(1993)
Cancer Res
, vol.53
, pp. 4477-4480
-
-
Boyle, J.O.1
Hakim, J.2
Koch, W.3
van der Riet, P.4
Hruban, R.H.5
Roa, R.A.6
Correo, R.7
Eby, Y.J.8
Ruppert, J.M.9
Sidransky, D.10
-
72
-
-
0027715215
-
p53 alterations in human squamous cell carcinomas and carcinoma cell lines
-
Caamano J, Zhang SY, Rosvold EA, Bauer B, Klein-Szanto AJ (1993) p53 alterations in human squamous cell carcinomas and carcinoma cell lines. Am J Pathol 142: 1131-1139.
-
(1993)
Am J Pathol
, vol.142
, pp. 1131-1139
-
-
Caamano, J.1
Zhang, S.Y.2
Rosvold, E.A.3
Bauer, B.4
Klein-Szanto, A.J.5
-
73
-
-
0342973089
-
TP53 mutation is related to poor prognosis after radiotherapy, but not surgery, in squamous cell carcinoma of the head and neck
-
Alsner J, Sorensen SB, Overgaard J (2001) TP53 mutation is related to poor prognosis after radiotherapy, but not surgery, in squamous cell carcinoma of the head and neck. Radiother Oncol 59: 179-185.
-
(2001)
Radiother Oncol
, vol.59
, pp. 179-185
-
-
Alsner, J.1
Sorensen, S.B.2
Overgaard, J.3
-
74
-
-
0032763639
-
Cumulative prognostic value of p53 mutations and bcl-2 protein expression in head-and-neck cancer treated by radiotherapy
-
Gallo O, Chiarelli I, Boddi V, Bocciolini C, Bruschini L, Porfirio B (1999) Cumulative prognostic value of p53 mutations and bcl-2 protein expression in head-and-neck cancer treated by radiotherapy. Int J Cancer 84: 573-579.
-
(1999)
Int J Cancer
, vol.84
, pp. 573-579
-
-
Gallo, O.1
Chiarelli, I.2
Boddi, V.3
Bocciolini, C.4
Bruschini, L.5
Porfirio, B.6
-
75
-
-
6844237661
-
Tumor angiogenesis and p53 mutations: Prognosis in head and neck cancer
-
Hegde PU, Brenski AC, Caldarelli DD, Hutchinson J, Panje WR, Wood NB, Leurgans S, Preisler HD, Taylor SG 4th et al (1998) Tumor angiogenesis and p53 mutations: prognosis in head and neck cancer. Arch Otolaryngol Head Neck Surg 124: 80-85.
-
(1998)
Arch Otolaryngol Head Neck Surg
, vol.124
, pp. 80-85
-
-
Hegde, P.U.1
Brenski, A.C.2
Caldarelli, D.D.3
Hutchinson, J.4
Panje, W.R.5
Wood, N.B.6
Leurgans, S.7
Preisler, H.D.8
Taylor, S.G.9
-
76
-
-
0036843814
-
A lack of association between p53 mutations and recurrent nasopharyngeal carcinomas refractory to radiotherapy
-
Chang KP, Hao SP, Lin SY, Tsao KC, Kuo TT, Tsai MH, Tseng CK, Tsang NM (2002) A lack of association between p53 mutations and recurrent nasopharyngeal carcinomas refractory to radiotherapy. Laryngoscope 112: 2015-2019.
-
(2002)
Laryngoscope
, vol.112
, pp. 2015-2019
-
-
Chang, K.P.1
Hao, S.P.2
Lin, S.Y.3
Tsao, K.C.4
Kuo, T.T.5
Tsai, M.H.6
Tseng, C.K.7
Tsang, N.M.8
-
77
-
-
0032874396
-
Patterns of p53 gene mutations in head and neck cancer: Full-length gene sequencing and results of primary radiotherapy
-
Saunders ME, MacKenzie R, Shipman R, Fransen E, Gilbert R, Jordan RC (1999) Patterns of p53 gene mutations in head and neck cancer: full-length gene sequencing and results of primary radiotherapy. Clin Cancer Res 5: 2455-2463.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2455-2463
-
-
Saunders, M.E.1
McKenzie, R.2
Shipman, R.3
Fransen, E.4
Gilbert, R.5
Jordan, R.C.6
-
78
-
-
0034688905
-
Clinical significance of p53 functional loss in squamous cell carcinoma of the oropharynx
-
Obata A, Eura M, Sasaki J, Saya H, Chikamatsu K, Tada M, Iggo RD, Yumoto E (2000) Clinical significance of p53 functional loss in squamous cell carcinoma of the oropharynx. Int J Cancer 89: 187-193.
-
(2000)
Int J Cancer
, vol.89
, pp. 187-193
-
-
Obata, A.1
Eura, M.2
Sasaki, J.3
Saya, H.4
Chikamatsu, K.5
Tada, M.6
Iggo, R.D.7
Yumoto, E.8
-
79
-
-
0031030869
-
p53 status and prognosis of locally advanced prostatic adenocarcinoma: A study based on RTOG 8610
-
Grignon DJ, Caplan R, Sarkar FH, Lawton CA, Hammond EH, Pilepich MV, Forman JD, Mesic J, Fu KK et al (1997) p53 status and prognosis of locally advanced prostatic adenocarcinoma: a study based on RTOG 8610. J Natl Cancer Inst 89: 158-165.
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 158-165
-
-
Grignon, D.J.1
Caplan, R.2
Sarkar, F.H.3
Lawton, C.A.4
Hammond, E.H.5
Pilepich, M.V.6
Forman, J.D.7
Mesic, J.8
Fu, K.K.9
-
80
-
-
0029868812
-
p53 immunohistochemical and genetic alterations are associated at high incidence with post-irradiated locally persistent prostate carcinoma
-
Prendergast NJ, Atkins MR, Schatte EC, Paulson DF, Walther PJ (1996) p53 immunohistochemical and genetic alterations are associated at high incidence with post-irradiated locally persistent prostate carcinoma. J Urol 155: 1685-1692.
-
(1996)
J Urol
, vol.155
, pp. 1685-1692
-
-
Prendergast, N.J.1
Atkins, M.R.2
Schatte, E.C.3
Paulson, D.F.4
Walther, P.J.5
-
81
-
-
0033000960
-
p53 gene alterations in prostate cancer after radiation failure and their association with clinical outcome: A molecular and immunohistochemical analysis
-
Rakozy C, Grignon DJ, Li Y, Gheiler E, Gururajanna B, Pontes JE, Sakr W, Wood DP Jr, Sarkar FH (1999) p53 gene alterations in prostate cancer after radiation failure and their association with clinical outcome: a molecular and immunohistochemical analysis. Pathol Res Pract 195: 129-135.
-
(1999)
Pathol Res Pract
, vol.195
, pp. 129-135
-
-
Rakozy, C.1
Grignon, D.J.2
Li, Y.3
Gheiler, E.4
Gururajanna, B.5
Pontes, J.E.6
Sakr, W.7
Wood, D.P.8
Sarkar, F.H.9
-
82
-
-
0034296241
-
Overexpression of p53 in prostate carcinoma is associated with improved overall survival but not predictive of response to radiotherapy
-
Incognito LS, Cazares LH, Schellhammer PF, Kuban DA, Van Dyk EO, Moriarty RP, Wright GL Jr, Somers KD (2000) Overexpression of p53 in prostate carcinoma is associated with improved overall survival but not predictive of response to radiotherapy. Int J Oncol 17: 761-769.
-
(2000)
Int J Oncol
, vol.17
, pp. 761-769
-
-
Incognito, L.S.1
Cazares, L.H.2
Schellhammer, P.F.3
Kuban, D.A.4
Van Dyk, E.O.5
Moriarty, R.P.6
Wright, G.L.7
Somers, K.D.8
-
84
-
-
0028172868
-
p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies
-
Wattel E, Preudhomme C, Hecquet B, Vanrumbeke M, Quesnel B, Dervite I, Morel P, Fenaux P (1994) p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies. Blood 84: 3148-3157.
-
(1994)
Blood
, vol.84
, pp. 3148-3157
-
-
Wattel, E.1
Preudhomme, C.2
Hecquet, B.3
Vanrumbeke, M.4
Quesnel, B.5
Dervite, I.6
Morel, P.7
Fenaux, P.8
-
85
-
-
79957949229
-
Mutational status of the TP53 gene as a predictor of response and survival in patients with chronic lymphocytic leukemia: Results from the LRF CLL4 trial
-
Gonzalez D, Martinez P, Wade R, Hockley S, Oscier D, Matutes E, Dearden CE, Richards SM, Catovsky D, Morgan GJ (2012) Mutational status of the TP53 gene as a predictor of response and survival in patients with chronic lymphocytic leukemia: results from the LRF CLL4 trial. J Clin Oncol 29: 2223-2229.
-
(2012)
J Clin Oncol
, vol.29
, pp. 2223-2229
-
-
Gonzalez, D.1
Martinez, P.2
Wade, R.3
Hockley, S.4
Oscier, D.5
Matutes, E.6
Dearden, C.E.7
Richards, S.M.8
Catovsky, D.9
Morgan, G.J.10
-
86
-
-
0028901763
-
Clinical significance of p53 mutations in newly diagnosed Burkitt's lymphoma and acute lymphoblastic leukemia: A report of 48 cases
-
Preudhomme C, Dervite I, Wattel E, Vanrumbeke M, Flactif M, Lai JL, Hecquet B, Coppin MC, Nelken B et al (1995) Clinical significance of p53 mutations in newly diagnosed Burkitt's lymphoma and acute lymphoblastic leukemia: a report of 48 cases. J Clin Oncol 13: 812-820.
-
(1995)
J Clin Oncol
, vol.13
, pp. 812-820
-
-
Preudhomme, C.1
Dervite, I.2
Wattel, E.3
Vanrumbeke, M.4
Flactif, M.5
Lai, J.L.6
Hecquet, B.7
Coppin, M.C.8
Nelken, B.9
-
87
-
-
0043130362
-
DNA sequence profile of TP53 gene mutations in childhood B-cell non-Hodgkin's lymphomas: Prognostic implications
-
Klumb CE, Furtado DR, de Resende LM, Carrico MK, Coelho AM, de Meis E, Maia RC, Rumjanek FD (2003) DNA sequence profile of TP53 gene mutations in childhood B-cell non-Hodgkin's lymphomas: prognostic implications. Eur J Haematol 71: 81-90.
-
(2003)
Eur J Haematol
, vol.71
, pp. 81-90
-
-
Klumb, C.E.1
Furtado, D.R.2
de Resende, L.M.3
Carrico, M.K.4
Coelho, A.M.5
de Meis, E.6
Maia, R.C.7
Rumjanek, F.D.8
-
88
-
-
0032931246
-
The TP53 genotype but not immunohistochemical result is predictive of response to cisplatin-based neoadjuvant therapy in stage III non-small cell lung cancer
-
Kandioler-Eckersberger D, Kappel S, Mittlbock M, Dekan G, Ludwig C, Janschek E, Pirker R, Wolner E, Eckersberger F (1999) The TP53 genotype but not immunohistochemical result is predictive of response to cisplatin-based neoadjuvant therapy in stage III non-small cell lung cancer. J Thorac Cardiovasc Surg 117: 744-750.
-
(1999)
J Thorac Cardiovasc Surg
, vol.117
, pp. 744-750
-
-
Kandioler-Eckersberger, D.1
Kappel, S.2
Mittlbock, M.3
Dekan, G.4
Ludwig, C.5
Janschek, E.6
Pirker, R.7
Wolner, E.8
Eckersberger, F.9
-
89
-
-
43049093034
-
Growing clinical evidence for the interaction of the p53 genotype and response to induction chemotherapy in advanced non-small cell lung cancer
-
Kandioler D, Stamatis G, Eberhardt W, Kappel S, Zochbauer-Muller S, Kuhrer I, Mittlbock M, Zwrtek R, Aigner C et al (2008) Growing clinical evidence for the interaction of the p53 genotype and response to induction chemotherapy in advanced non-small cell lung cancer. J Thorac Cardiovasc Surg 135: 1036-1041.
-
(2008)
J Thorac Cardiovasc Surg
, vol.135
, pp. 1036-1041
-
-
Kandioler, D.1
Stamatis, G.2
Eberhardt, W.3
Kappel, S.4
Zochbauer-Muller, S.5
Kuhrer, I.6
Mittlbock, M.7
Zwrtek, R.8
Aigner, C.9
-
90
-
-
0034663195
-
p53 mutations do not predict response to paclitaxel in metastatic nonsmall cell lung carcinoma
-
King TC, Akerley W, Fan AC, Moore T, Mangray S, Hsiu Chen M, Safran H (2000) p53 mutations do not predict response to paclitaxel in metastatic nonsmall cell lung carcinoma. Cancer 89: 769-773.
-
(2000)
Cancer
, vol.89
, pp. 769-773
-
-
King, T.C.1
Akerley, W.2
Fan, A.C.3
Moore, T.4
Mangray, S.5
Hsiu Chen, M.6
Safran, H.7
-
91
-
-
9544220646
-
p53 mutations do not predict response to paclitaxel/radiation for nonsmall cell lung carcinoma
-
Safran H, King T, Choy H, Gollerkeri A, Kwakwa H, Lopez F, Cole B, Myers J, Tarpey J, Rosmarin A (1996) p53 mutations do not predict response to paclitaxel/radiation for nonsmall cell lung carcinoma. Cancer 78: 1203-1210.
-
(1996)
Cancer
, vol.78
, pp. 1203-1210
-
-
Safran, H.1
King, T.2
Choy, H.3
Gollerkeri, A.4
Kwakwa, H.5
Lopez, F.6
Cole, B.7
Myers, J.8
Tarpey, J.9
Rosmarin, A.10
-
92
-
-
0027375963
-
Molecular genetic analysis of the mechanism of tumorigenesis in acoustic neuroma
-
Irving RM, Moffat DA, Hardy DG, Barton DE, Xuereb JH, Maher ER (1993) Molecular genetic analysis of the mechanism of tumorigenesis in acoustic neuroma. Arch Otolaryngol Head Neck Surg 119: 1222-1228.
-
(1993)
Arch Otolaryngol Head Neck Surg
, vol.119
, pp. 1222-1228
-
-
Irving, R.M.1
Moffat, D.A.2
Hardy, D.G.3
Barton, D.E.4
Xuereb, J.H.5
Maher, E.R.6
-
93
-
-
0031593952
-
p53 tumor suppressor gene in acoustic neuromas
-
Monoh K, Ishikawa K, Yasui N, Mineura K, Andoh H, Togawa K (1998) p53 tumor suppressor gene in acoustic neuromas. Acta Otolaryngol Suppl 537: 11-15.
-
(1998)
Acta Otolaryngol Suppl
, vol.537
, pp. 11-15
-
-
Monoh, K.1
Ishikawa, K.2
Yasui, N.3
Mineura, K.4
Andoh, H.5
Togawa, K.6
-
94
-
-
73349110095
-
Radiobiology of vestibular schwannomas: Mechanisms of radioresistance and potential targets for therapeutic sensitization
-
Yeung AH, Sughrue ME, Kane AJ, Tihan T, Cheung SW, Parsa AT (2009) Radiobiology of vestibular schwannomas: mechanisms of radioresistance and potential targets for therapeutic sensitization. Neurosurg Focus 27: E2.
-
(2009)
Neurosurg Focus
, vol.27
-
-
Yeung, A.H.1
Sughrue, M.E.2
Kane, A.J.3
Tihan, T.4
Cheung, S.W.5
Parsa, A.T.6
-
95
-
-
73349103157
-
Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: A prospective translational study of the German Glioma Network
-
Weller M, Felsberg J, Hartmann C, Berger H, Steinbach JP, Schramm J, Westphal M, Schackert G, Simon M et al (2009) Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network. J Clin Oncol 27: 5743-5750.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5743-5750
-
-
Weller, M.1
Felsberg, J.2
Hartmann, C.3
Berger, H.4
Steinbach, J.P.5
Schramm, J.6
Westphal, M.7
Schackert, G.8
Simon, M.9
-
96
-
-
77951629484
-
TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors
-
Tabori U, Shlien A, Baskin B, Levitt S, Ray P, Alon N, Hawkins C, Bouffet E, Pienkowska M et al (2010) TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors. J Clin Oncol 28: 1995-2001.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1995-2001
-
-
Tabori, U.1
Shlien, A.2
Baskin, B.3
Levitt, S.4
Ray, P.5
Alon, N.6
Hawkins, C.7
Bouffet, E.8
Pienkowska, M.9
-
97
-
-
0035105560
-
The results of colorectal cancer treatment by p53 status: Treatment-specific overview
-
discussion 333-334
-
Petersen S, Thames HD, Nieder C, Petersen C, Baumann M (2001) The results of colorectal cancer treatment by p53 status: treatment-specific overview. Dis Colon Rectum 44: 322-333. discussion 333-334.
-
(2001)
Dis Colon Rectum
, vol.44
, pp. 322-333
-
-
Petersen, S.1
Thames, H.D.2
Nieder, C.3
Petersen, C.4
Baumann, M.5
-
98
-
-
84866636175
-
P53 status as a predictive biomarker for patients receiving neoadjuvant radiation-based treatment: A meta-analysis in rectal cancer
-
Chen MB, Wu XY, Yu R, Li C, Wang LQ, Shen W, Lu PH (2012) P53 status as a predictive biomarker for patients receiving neoadjuvant radiation-based treatment: a meta-analysis in rectal cancer. PLoS One 7: e45388.
-
(2012)
PLoS One
, vol.7
-
-
Chen, M.B.1
Wu, X.Y.2
Yu, R.3
Li, C.4
Wang, L.Q.5
Shen, W.6
Lu, P.H.7
-
99
-
-
0036208768
-
TP53 genotype but not p53 immunohistochemical result predicts response to preoperative short-term radiotherapy in rectal cancer
-
Kandioler D, Zwrtek R, Ludwig C, Janschek E, Ploner M, Hofbauer F, Kuhrer I, Kappel S, Wrba F et al (2002) TP53 genotype but not p53 immunohistochemical result predicts response to preoperative short-term radiotherapy in rectal cancer. Ann Surg 235: 493-498.
-
(2002)
Ann Surg
, vol.235
, pp. 493-498
-
-
Kandioler, D.1
Zwrtek, R.2
Ludwig, C.3
Janschek, E.4
Ploner, M.5
Hofbauer, F.6
Kuhrer, I.7
Kappel, S.8
Wrba, F.9
-
100
-
-
0037054943
-
Prognostic value of P53 mutations in rectal carcinoma
-
Rebischung C, Gerard JP, Gayet J, Thomas G, Hamelin R, Laurent-Puig P (2002) Prognostic value of P53 mutations in rectal carcinoma. Int J Cancer 100: 131-135.
-
(2002)
Int J Cancer
, vol.100
, pp. 131-135
-
-
Rebischung, C.1
Gerard, J.P.2
Gayet, J.3
Thomas, G.4
Hamelin, R.5
Laurent-Puig, P.6
-
101
-
-
24944525406
-
Determination of TP53 mutation is more relevant than microsatellite instability status for the prediction of disease-free survival in adjuvant-treated stage III colon cancer patients
-
Westra JL, Schaapveld M, Hollema H, de Boer JP, Kraak MM, de Jong D, ter Elst A, Mulder NH, Buys CH et al (2005) Determination of TP53 mutation is more relevant than microsatellite instability status for the prediction of disease-free survival in adjuvant-treated stage III colon cancer patients. J Clin Oncol 23: 5635-5643.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5635-5643
-
-
Westra, J.L.1
Schaapveld, M.2
Hollema, H.3
de Boer, J.P.4
Kraak, M.M.5
de Jong, D.6
ter Elst, A.7
Mulder, N.H.8
Buys, C.H.9
-
102
-
-
0030035584
-
p53 mutations as a possible predictor of response to chemotherapy in metastatic colorectal carcinomas
-
Benhattar J, Cerottini JP, Saraga E, Metthez G, Givel JC (1996) p53 mutations as a possible predictor of response to chemotherapy in metastatic colorectal carcinomas. Int J Cancer 69: 190-192.
-
(1996)
Int J Cancer
, vol.69
, pp. 190-192
-
-
Benhattar, J.1
Cerottini, J.P.2
Saraga, E.3
Metthez, G.4
Givel, J.C.5
-
103
-
-
14444285483
-
p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: An analysis of response and survival
-
Lenz HJ, Hayashi K, Salonga D, Danenberg KD, Danenberg PV, Metzger R, Banerjee D, Bertino JR, Groshen S et al (1998) p53 point mutations and thymidylate synthase messenger RNA levels in disseminated colorectal cancer: an analysis of response and survival. Clin Cancer Res 4: 1243-1250.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 1243-1250
-
-
Lenz, H.J.1
Hayashi, K.2
Salonga, D.3
Danenberg, K.D.4
Danenberg, P.V.5
Metzger, R.6
Banerjee, D.7
Bertino, J.R.8
Groshen, S.9
-
104
-
-
2642655267
-
p53 sequence analysis predicts treatment response and outcome of patients with esophageal carcinoma
-
Ribeiro U Jr, Finkelstein SD, Safatle-Ribeiro AV, Landreneau RJ, Clarke MR, Bakker A, Swalsky PA, Gooding WE, Posner MC (1998) p53 sequence analysis predicts treatment response and outcome of patients with esophageal carcinoma. Cancer 83: 7-18.
-
(1998)
Cancer
, vol.83
, pp. 7-18
-
-
Ribeiro, U.1
Finkelstein, S.D.2
Safatle-Ribeiro, A.V.3
Landreneau, R.J.4
Clarke, M.R.5
Bakker, A.6
Swalsky, P.A.7
Gooding, W.E.8
Posner, M.C.9
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