메뉴 건너뛰기




Volumn 253, Issue 2, 1999, Pages 432-439

Accumulation of mutant p53(V143A) modulates the growth, clonogenicity, and radiochemosensitivity of malignant glioma cells independent of endogenous p53 status

Author keywords

Apoptosis; Chemotherapy; Glioma; p21(WAF1 CIP1); p53; Radiotherapy

Indexed keywords

CAMPTOTHECIN; CARMUSTINE; CISPLATIN; CYTOTOXIC AGENT; PACLITAXEL; PROTEIN P53; TENIPOSIDE; TOPOTECAN; VINCRISTINE;

EID: 0033572965     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1999.4654     Document Type: Article
Times cited : (25)

References (42)
  • 1
    • 0030705168 scopus 로고    scopus 로고
    • Loss of function and p53 protein stabilization
    • Blagosklonny M. V. Loss of function and p53 protein stabilization. Oncogene. 15:1997;1889-1893.
    • (1997) Oncogene , vol.15 , pp. 1889-1893
    • Blagosklonny, M.V.1
  • 2
    • 0025611503 scopus 로고
    • Genetic mechanisms of tumor suppression by the human p53 gene
    • Chen P. L., Chen Y. M., Bookstein R., Lee W. H. Genetic mechanisms of tumor suppression by the human p53 gene. Science. 250:1990;1576-1580.
    • (1990) Science , vol.250 , pp. 1576-1580
    • Chen, P.L.1    Chen, Y.M.2    Bookstein, R.3    Lee, W.H.4
  • 3
    • 0026076012 scopus 로고
    • Alterations in tumor development in vivo mediated by expression of wild type or mutant p53 proteins
    • Shaulsky G., Goldfinger N., Rotter V. Alterations in tumor development in vivo mediated by expression of wild type or mutant p53 proteins. Cancer Res. 51:1991;5232-5237.
    • (1991) Cancer Res. , vol.51 , pp. 5232-5237
    • Shaulsky, G.1    Goldfinger, N.2    Rotter, V.3
  • 6
    • 0032574788 scopus 로고    scopus 로고
    • An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control
    • Gualberto A., Aldape K., Kozakiewicz K., Tlsty T. D. An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control. Proc. Natl. Acad. Sci. USA. 95:1998;5166-5171.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5166-5171
    • Gualberto, A.1    Aldape, K.2    Kozakiewicz, K.3    Tlsty, T.D.4
  • 7
    • 0032543718 scopus 로고    scopus 로고
    • Gain of function phenotype of tumor-derived mutant p53 requires the oligomerization/nonsequence-specific nucleic acid-binding domain
    • Lányi A., Deb D., Seymour R. C., Ludes-Meyers J. H., Subler M. A., Deb S. Gain of function phenotype of tumor-derived mutant p53 requires the oligomerization/nonsequence-specific nucleic acid-binding domain. Oncogene. 16:1998;3169-3176.
    • (1998) Oncogene , vol.16 , pp. 3169-3176
    • Lányi, A.1    Deb, D.2    Seymour, R.C.3    Ludes-Meyers, J.H.4    Subler, M.A.5    Deb, S.6
  • 10
    • 0031869758 scopus 로고    scopus 로고
    • Predicting response to cancer chemotherapy: The role of p53
    • Weller M. Predicting response to cancer chemotherapy: The role of p53. Cell Tissue Res. 292:1998;435-445.
    • (1998) Cell Tissue Res. , vol.292 , pp. 435-445
    • Weller, M.1
  • 11
    • 0029397307 scopus 로고
    • The p53 gene and its role in human brain tumors
    • Bögler O., Huang H. J. S., Kleihues P., Cavenee W. K. The p53 gene and its role in human brain tumors. Glia. 15:1995;308-327.
    • (1995) Glia , vol.15 , pp. 308-327
    • Bögler, O.1    Huang, H.J.S.2    Kleihues, P.3    Cavenee, W.K.4
  • 12
    • 0031705691 scopus 로고    scopus 로고
    • P53 and brain tumors: From gene mutations to gene therapy
    • Fulci G., Ishii N., Van Meir E. G. p53 and brain tumors: From gene mutations to gene therapy. Brain Pathol. 8:1998;599-613.
    • (1998) Brain Pathol. , vol.8 , pp. 599-613
    • Fulci, G.1    Ishii, N.2    Van Meir, E.G.3
  • 14
    • 0029094065 scopus 로고
    • A tiger behind many doors: Multiple genetic pathways to malignant glioma
    • Louis D. N., Gusella J. F. A tiger behind many doors: Multiple genetic pathways to malignant glioma. Trends Genet. 11:1995;412-415.
    • (1995) Trends Genet. , vol.11 , pp. 412-415
    • Louis, D.N.1    Gusella, J.F.2
  • 15
    • 0030017885 scopus 로고    scopus 로고
    • Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas
    • Watanabe K., Tachibana O., Sato K., Yonekawa Y., Kleihues P., Ohgaki H. Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol. 6:1996;217-224.
    • (1996) Brain Pathol. , vol.6 , pp. 217-224
    • Watanabe, K.1    Tachibana, O.2    Sato, K.3    Yonekawa, Y.4    Kleihues, P.5    Ohgaki, H.6
  • 16
    • 0027944070 scopus 로고
    • Prognostic implications of p53 overexpression in supratentorial astrocytic tumors
    • Chozick B. S., Pezzullo J. C., Epstein M. H., Finch P. W. Prognostic implications of p53 overexpression in supratentorial astrocytic tumors. Neurosurgery. 35:1994;831-838.
    • (1994) Neurosurgery , vol.35 , pp. 831-838
    • Chozick, B.S.1    Pezzullo, J.C.2    Epstein, M.H.3    Finch, P.W.4
  • 17
    • 0031985148 scopus 로고    scopus 로고
    • Mutation of the p53 gene in human astrocytic tumors correlates with increased resistance to DNA-damaging agents but not to anti-microtubule anti-cancer agents
    • Iwadate Y., Tagawa M., Fujimoto S., Hirose M., Namba H., Sueyoshi K., Sakiyama S., Yamaura A. Mutation of the p53 gene in human astrocytic tumors correlates with increased resistance to DNA-damaging agents but not to anti-microtubule anti-cancer agents. Br. J. Cancer. 77:1998;547-551.
    • (1998) Br. J. Cancer , vol.77 , pp. 547-551
    • Iwadate, Y.1    Tagawa, M.2    Fujimoto, S.3    Hirose, M.4    Namba, H.5    Sueyoshi, K.6    Sakiyama, S.7    Yamaura, A.8
  • 18
    • 0027946403 scopus 로고
    • Prognostic significance of p53 immunoreactivity in adult patients with supratentorial fibrillary astrocytic neoplasms
    • Montine T. J., Bruner J. M., Vandersteenhoven J. J., Dodge R. K., Burger P. C. Prognostic significance of p53 immunoreactivity in adult patients with supratentorial fibrillary astrocytic neoplasms. Diagn. Mol. Pathol. 3:1994;240-245.
    • (1994) Diagn. Mol. Pathol. , vol.3 , pp. 240-245
    • Montine, T.J.1    Bruner, J.M.2    Vandersteenhoven, J.J.3    Dodge, R.K.4    Burger, P.C.5
  • 20
    • 0031033359 scopus 로고    scopus 로고
    • Analysis of proliferation markers and p53 expression in gliomas of astrocytic origin: Relationships and prognostic value
    • Cunningham J. M., Kimmel D. W., Scheithauer B. W., O'Fallon J. R., Novotny P. J., Jenkins R. B. Analysis of proliferation markers and p53 expression in gliomas of astrocytic origin: Relationships and prognostic value. J. Neurosurg. 86:1997;121-130.
    • (1997) J. Neurosurg. , vol.86 , pp. 121-130
    • Cunningham, J.M.1    Kimmel, D.W.2    Scheithauer, B.W.3    O'Fallon, J.R.4    Novotny, P.J.5    Jenkins, R.B.6
  • 25
    • 0027313366 scopus 로고
    • A correlative study of p53 protein alteration and p53 gene mutation in glioblastoma multiforme
    • Newcomb E. W., Madonia W. J., Pisharody S., Lang F. F., Koslow M., Miller D. C. A correlative study of p53 protein alteration and p53 gene mutation in glioblastoma multiforme. Brain Pathol. 3:1993;229-235.
    • (1993) Brain Pathol. , vol.3 , pp. 229-235
    • Newcomb, E.W.1    Madonia, W.J.2    Pisharody, S.3    Lang, F.F.4    Koslow, M.5    Miller, D.C.6
  • 26
    • 0027196974 scopus 로고
    • Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations
    • Reifenberger G., Liu L., Ichimura K., Schmidt E. E., Collins V. P. Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations. Cancer Res. 53:1993;2736-2739.
    • (1993) Cancer Res. , vol.53 , pp. 2736-2739
    • Reifenberger, G.1    Liu, L.2    Ichimura, K.3    Schmidt, E.E.4    Collins, V.P.5
  • 29
    • 0029783722 scopus 로고    scopus 로고
    • A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis
    • Friedlander P., Haupt Y., Prives C., Oren M. A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis. Mol. Cell. Biol. 16:1996;4961-4971.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4961-4971
    • Friedlander, P.1    Haupt, Y.2    Prives, C.3    Oren, M.4
  • 30
    • 0027931008 scopus 로고
    • Cell cycle arrests and radiosensitivity of human tumour cell lines: Dependence on wild-type p53 for radiosensitivity
    • McIlwrath A. J., Vasey P. A., Ross G. M., Brown R. Cell cycle arrests and radiosensitivity of human tumour cell lines: Dependence on wild-type p53 for radiosensitivity. Cancer Res. 54:1994;3718-3722.
    • (1994) Cancer Res. , vol.54 , pp. 3718-3722
    • McIlwrath, A.J.1    Vasey, P.A.2    Ross, G.M.3    Brown, R.4
  • 31
    • 0030465009 scopus 로고    scopus 로고
    • Cisplatin, camptothecin, and Taxol sensitivities of cells with p53-associated drug resistance
    • Vasey P. A., Jones N. A., Jenkins S., Dive C., Brown R. Cisplatin, camptothecin, and Taxol sensitivities of cells with p53-associated drug resistance. Mol. Pharmacol. 50:1996;1536-1540.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 1536-1540
    • Vasey, P.A.1    Jones, N.A.2    Jenkins, S.3    Dive, C.4    Brown, R.5
  • 32
    • 0031684842 scopus 로고    scopus 로고
    • Induction of p53-dependent and independent cellular responses by topoisomerase 1 inhibitors
    • McDonald A. C., Brown R. Induction of p53-dependent and independent cellular responses by topoisomerase 1 inhibitors. Br. J. Cancer. 78:1998;745-751.
    • (1998) Br. J. Cancer , vol.78 , pp. 745-751
    • McDonald, A.C.1    Brown, R.2
  • 35
    • 0025040233 scopus 로고
    • Suppression of human colorectal carcinoma cell growth by wild-type p53
    • Baker S. J., Markowitz S., Fearon E. R., Willson J. K., Vogelstein B. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science. 249:1990;912-915.
    • (1990) Science , vol.249 , pp. 912-915
    • Baker, S.J.1    Markowitz, S.2    Fearon, E.R.3    Willson, J.K.4    Vogelstein, B.5
  • 36
    • 0028892881 scopus 로고
    • Dominant-negative p53 can restore tumorigenicity of L-929 cells in immunocompetent mice
    • Appleman L. J., Frey A. B. Dominant-negative p53 can restore tumorigenicity of L-929 cells in immunocompetent mice. Int. J. Cancer. 63:1995;576-583.
    • (1995) Int. J. Cancer , vol.63 , pp. 576-583
    • Appleman, L.J.1    Frey, A.B.2
  • 39
    • 0028842340 scopus 로고
    • A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice
    • Harvey M., Vogel H., Morris D., Bradley A., Bernstein A., Donehower L. A. A mutant p53 transgene accelerates tumour development in heterozygous but not nullizygous p53-deficient mice. Nat. Genet. 9:1995;305-311.
    • (1995) Nat. Genet. , vol.9 , pp. 305-311
    • Harvey, M.1    Vogel, H.2    Morris, D.3    Bradley, A.4    Bernstein, A.5    Donehower, L.A.6
  • 40
    • 0031746153 scopus 로고    scopus 로고
    • Suppression of tumorigenic and metastatic potentials of human melanoma cell lines by mutated (143 Val-Ala) p53
    • Rauth S., Green A., Kichina J., Shilkaitis A. Suppression of tumorigenic and metastatic potentials of human melanoma cell lines by mutated (143 Val-Ala) p53. Br. J. Cancer. 77:1998;2215-2222.
    • (1998) Br. J. Cancer , vol.77 , pp. 2215-2222
    • Rauth, S.1    Green, A.2    Kichina, J.3    Shilkaitis, A.4
  • 42
    • 0027742856 scopus 로고
    • Aberrant p53 expression in astrocytic neoplasms of brain: Association with proliferation
    • Haapasalo H., Isola J., Sallinen P., Kalimo H., Helin H., Rantala I. Aberrant p53 expression in astrocytic neoplasms of brain: Association with proliferation. Am. J. Pathol. 142:1993;1347-1351.
    • (1993) Am. J. Pathol. , vol.142 , pp. 1347-1351
    • Haapasalo, H.1    Isola, J.2    Sallinen, P.3    Kalimo, H.4    Helin, H.5    Rantala, I.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.