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Volumn 16, Issue 11, 2014, Pages

New Developments in the Genetics of Bipolar Disorder

Author keywords

Association, Sequencing; Bipolar disorder; Genetics; Methylation; Subphenotype

Indexed keywords

DNA; LITHIUM SALT;

EID: 84920287742     PISSN: 15233812     EISSN: 15351645     Source Type: Journal    
DOI: 10.1007/s11920-014-0493-5     Document Type: Review
Times cited : (39)

References (72)
  • 1
    • 0034158465 scopus 로고    scopus 로고
    • Searching high and low: a review of the genetics of bipolar disorder
    • PID: 11254025, COI: 1:STN:280:DC%2BD3M3lvFWisw%3D%3D
    • Potash JB, DePaulo Jr JR. Searching high and low: a review of the genetics of bipolar disorder. Bipolar Disord. 2000;2(1):8–26.
    • (2000) Bipolar Disord , vol.2 , Issue.1 , pp. 8-26
    • Potash, J.B.1    DePaulo, J.R.2
  • 2
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature. 2007;447(7145):661–78.
    • (2007) Nature , vol.447 , Issue.7145 , pp. 661-678
    • Wellcome Trust Case Control Consortium1
  • 3
    • 38349128462 scopus 로고    scopus 로고
    • A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder
    • PID: 17486107, COI: 1:CAS:528:DC%2BD1cXnt1GmsA%3D%3D
    • Baum AE et al. A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. Mol Psychiatry. 2008;13(2):197–207.
    • (2008) Mol Psychiatry , vol.13 , Issue.2 , pp. 197-207
    • Baum, A.E.1
  • 4
    • 50449089356 scopus 로고    scopus 로고
    • Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder
    • PID: 18711365, COI: 1:CAS:528:DC%2BD1cXhtVGgt77O
    • Ferreira MA et al. Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet. 2008;40(9):1056–8.
    • (2008) Nat Genet , vol.40 , Issue.9 , pp. 1056-1058
    • Ferreira, M.A.1
  • 5
    • 43949118134 scopus 로고    scopus 로고
    • Whole-genome association study of bipolar disorder
    • PID: 18317468, COI: 1:CAS:528:DC%2BD1cXlvFOjt7g%3D
    • Sklar P et al. Whole-genome association study of bipolar disorder. Mol Psychiatry. 2008;13(6):558–69.
    • (2008) Mol Psychiatry , vol.13 , Issue.6 , pp. 558-569
    • Sklar, P.1
  • 6
    • 79955473843 scopus 로고    scopus 로고
    • Genome-wide association study of bipolar I disorder in the Han Chinese population
    • PID: 20386566, COI: 1:CAS:528:DC%2BC3MXltVGlurc%3D
    • Lee MT et al. Genome-wide association study of bipolar I disorder in the Han Chinese population. Mol Psychiatry. 2011;16(5):548–56.
    • (2011) Mol Psychiatry , vol.16 , Issue.5 , pp. 548-556
    • Lee, M.T.1
  • 7
    • 72049127779 scopus 로고    scopus 로고
    • Preliminary genome-wide association study of bipolar disorder in the Japanese population
    • PID: 19259986, COI: 1:CAS:528:DC%2BC3cXitlCktA%3D%3D
    • Hattori E et al. Preliminary genome-wide association study of bipolar disorder in the Japanese population. Am J Med Genet B Neuropsychiatr Genet. 2009;150B(8):1110–7.
    • (2009) Am J Med Genet B Neuropsychiatr Genet , vol.150B , Issue.8 , pp. 1110-1117
    • Hattori, E.1
  • 8
    • 77956262527 scopus 로고    scopus 로고
    • A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample
    • PID: 20451256
    • Djurovic S et al. A genome-wide association study of bipolar disorder in Norwegian individuals, followed by replication in Icelandic sample. J Affect Disord. 2010;126(1–2):312–6.
    • (2010) J Affect Disord , vol.126 , Issue.1-2 , pp. 312-316
    • Djurovic, S.1
  • 9
    • 79952485391 scopus 로고    scopus 로고
    • Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder
    • PID: 21353194, COI: 1:CAS:528:DC%2BC3MXjtFOht70%3D
    • Cichon S et al. Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. Am J Hum Genet. 2011;88(3):372–81.
    • (2011) Am J Hum Genet , vol.88 , Issue.3 , pp. 372-381
    • Cichon, S.1
  • 10
    • 80053630934 scopus 로고    scopus 로고
    • Genome-wide association study on bipolar disorder in the Bulgarian population
    • PID: 21771265, COI: 1:CAS:528:DC%2BC3MXhsVOjs7nI
    • Yosifova A et al. Genome-wide association study on bipolar disorder in the Bulgarian population. Genes Brain Behav. 2011;10(7):789–97.
    • (2011) Genes Brain Behav , vol.10 , Issue.7 , pp. 789-797
    • Yosifova, A.1
  • 11
    • 84891512242 scopus 로고    scopus 로고
    • Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1
    • PID: 24387768
    • Xu W et al. Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1. BMC Med Genet. 2014;15:2.
    • (2014) BMC Med Genet , vol.15 , pp. 2
    • Xu, W.1
  • 12
    • 79959813723 scopus 로고    scopus 로고
    • Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes
    • PID: 21738484, COI: 1:CAS:528:DC%2BC3MXovVygsrc%3D
    • Smith EN et al. Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes. PLoS Genet. 2011;7(6):e1002134.
    • (2011) PLoS Genet , vol.7 , Issue.6 , pp. e1002134
    • Smith, E.N.1
  • 13
    • 67651158803 scopus 로고    scopus 로고
    • Genome-wide association study of bipolar disorder in European American and African American individuals
    • PID: 19488044, COI: 1:CAS:528:DC%2BD1MXptVCjtLY%3D
    • Smith EN et al. Genome-wide association study of bipolar disorder in European American and African American individuals. Mol Psychiatry. 2009;14(8):755–63.
    • (2009) Mol Psychiatry , vol.14 , Issue.8 , pp. 755-763
    • Smith, E.N.1
  • 14
    • 80053385384 scopus 로고    scopus 로고
    • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4
    • Psychiatric Genomics Consortium-Bipolar Disorder Working Group. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet. 2011;43(10):977–83.
    • (2011) Nat Genet , vol.43 , Issue.10 , pp. 977-983
    • Psychiatric Genomics Consortium-Bipolar Disorder Working Group1
  • 15
    • 84896374339 scopus 로고    scopus 로고
    • Genome-wide association study reveals two new risk loci for bipolar disorder
    • PID: 24618891, The largest BPD GWAS to date with >24,000 patients and controls
    • Muhleisen TW et al. Genome-wide association study reveals two new risk loci for bipolar disorder. Nat Commun. 2014;5:3339. The largest BPD GWAS to date with >24,000 patients and controls.
    • (2014) Nat Commun , vol.5 , pp. 3339
    • Muhleisen, T.W.1
  • 16
    • 84873058959 scopus 로고    scopus 로고
    • Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder
    • PID: 22182935, COI: 1:CAS:528:DC%2BC3sXhsVKntro%3D, This study of >17,000 subjects implicated TRANK1 in BPD
    • Chen DT et al. Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. Mol Psychiatry. 2013;18(2):195–205. This study of >17,000 subjects implicated TRANK1 in BPD.
    • (2013) Mol Psychiatry , vol.18 , Issue.2 , pp. 195-205
    • Chen, D.T.1
  • 17
    • 84902204761 scopus 로고    scopus 로고
    • Identification of pathways for bipolar disorder: a meta-analysis
    • PID: 24718920, COI: 1:CAS:528:DC%2BC2cXhtFKksrjI
    • Nurnberger Jr JI et al. Identification of pathways for bipolar disorder: a meta-analysis. JAMA Psychiatry. 2014;71(6):657–64.
    • (2014) JAMA Psychiatry , vol.71 , Issue.6 , pp. 657-664
    • Nurnberger, J.I.1
  • 18
    • 84878898276 scopus 로고    scopus 로고
    • The risk variant in ODZ4 for bipolar disorder impacts on amygdala activation during reward processing
    • PID: 23611537, COI: 1:CAS:528:DC%2BC3sXhtF2qtLrL
    • Heinrich A et al. The risk variant in ODZ4 for bipolar disorder impacts on amygdala activation during reward processing. Bipolar Disord. 2013;15(4):440–5.
    • (2013) Bipolar Disord , vol.15 , Issue.4 , pp. 440-445
    • Heinrich, A.1
  • 19
    • 84865524813 scopus 로고    scopus 로고
    • The impact of the CACNA1C risk allele on limbic structures and facial emotions recognition in bipolar disorder subjects and healthy controls
    • PID: 22464935, COI: 1:CAS:528:DC%2BC38XkvFWitLw%3D
    • Soeiro-de-Souza MG et al. The impact of the CACNA1C risk allele on limbic structures and facial emotions recognition in bipolar disorder subjects and healthy controls. J Affect Disord. 2012;141(1):94–101.
    • (2012) J Affect Disord , vol.141 , Issue.1 , pp. 94-101
    • Soeiro-de-Souza, M.G.1
  • 20
    • 84885387509 scopus 로고    scopus 로고
    • The CACNA1C risk allele selectively impacts on executive function in bipolar type I disorder
    • PID: 23406546, COI: 1:CAS:528:DC%2BC3sXhs1eksLvL
    • Soeiro-de-Souza MG et al. The CACNA1C risk allele selectively impacts on executive function in bipolar type I disorder. Acta Psychiatr Scand. 2013;128(5):362–9.
    • (2013) Acta Psychiatr Scand , vol.128 , Issue.5 , pp. 362-369
    • Soeiro-de-Souza, M.G.1
  • 21
    • 84874261811 scopus 로고    scopus 로고
    • CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls
    • PID: 23437284, COI: 1:CAS:528:DC%2BC3sXjsF2hsLw%3D
    • Tesli M et al. CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls. PLoS ONE. 2013;8(2):e56970.
    • (2013) PLoS ONE , vol.8 , Issue.2 , pp. e56970
    • Tesli, M.1
  • 22
    • 79959249145 scopus 로고    scopus 로고
    • The CACNA1C and ANK3 risk alleles impact on affective personality traits and startle reactivity but not on cognition or gating in healthy males
    • PID: 21676128
    • Roussos P et al. The CACNA1C and ANK3 risk alleles impact on affective personality traits and startle reactivity but not on cognition or gating in healthy males. Bipolar Disord. 2011;13(3):250–9.
    • (2011) Bipolar Disord , vol.13 , Issue.3 , pp. 250-259
    • Roussos, P.1
  • 23
    • 79551617320 scopus 로고    scopus 로고
    • The cognitive impact of the ANK3 risk variant for bipolar disorder: initial evidence of selectivity to signal detection during sustained attention
    • PID: 21304963, COI: 1:CAS:528:DC%2BC3MXhvFahs74%3D
    • Ruberto G et al. The cognitive impact of the ANK3 risk variant for bipolar disorder: initial evidence of selectivity to signal detection during sustained attention. PLoS ONE. 2011;6(1):e16671.
    • (2011) PLoS ONE , vol.6 , Issue.1 , pp. e16671
    • Ruberto, G.1
  • 24
    • 78650241063 scopus 로고    scopus 로고
    • The CACNA1C risk variant for bipolar disorder influences limbic activity
    • PID: 20351721, COI: 1:STN:280:DC%2BC3cbotFensQ%3D%3D
    • Wessa M et al. The CACNA1C risk variant for bipolar disorder influences limbic activity. Mol Psychiatry. 2010;15(12):1126–7.
    • (2010) Mol Psychiatry , vol.15 , Issue.12 , pp. 1126-1127
    • Wessa, M.1
  • 25
    • 84876671670 scopus 로고    scopus 로고
    • The impact of CACNA1C allelic variation on effective connectivity during emotional processing in bipolar disorder
    • PID: 22614292, COI: 1:STN:280:DC%2BC38nltVeqtQ%3D%3D
    • Radua J et al. The impact of CACNA1C allelic variation on effective connectivity during emotional processing in bipolar disorder. Mol Psychiatry. 2013;18(5):526–7.
    • (2013) Mol Psychiatry , vol.18 , Issue.5 , pp. 526-527
    • Radua, J.1
  • 26
    • 84890022588 scopus 로고    scopus 로고
    • Independent modulation of engagement and connectivity of the facial network during affect processing by CACNA1C and ANK3 risk genes for bipolar disorder
    • PID: 24108394, COI: 1:CAS:528:DC%2BC3sXhvF2ktbjM
    • Dima D et al. Independent modulation of engagement and connectivity of the facial network during affect processing by CACNA1C and ANK3 risk genes for bipolar disorder. JAMA Psychiatry. 2013;70(12):1303–11.
    • (2013) JAMA Psychiatry , vol.70 , Issue.12 , pp. 1303-1311
    • Dima, D.1
  • 27
    • 84892898782 scopus 로고    scopus 로고
    • The impact of a CACNA1C gene polymorphism on learning and hippocampal formation in healthy individuals: a diffusion tensor imaging study
    • PID: 24269271, COI: 1:CAS:528:DC%2BC2cXislOgsLo%3D
    • Dietsche B et al. The impact of a CACNA1C gene polymorphism on learning and hippocampal formation in healthy individuals: a diffusion tensor imaging study. Neuroimage. 2014;89:256–61.
    • (2014) Neuroimage , vol.89 , pp. 256-261
    • Dietsche, B.1
  • 28
    • 77956359560 scopus 로고    scopus 로고
    • Genetic variation in CACNA1C affects brain circuitries related to mental illness
    • PID: 20819988
    • Bigos KL et al. Genetic variation in CACNA1C affects brain circuitries related to mental illness. Arch Gen Psychiatry. 2010;67(9):939–45.
    • (2010) Arch Gen Psychiatry , vol.67 , Issue.9 , pp. 939-945
    • Bigos, K.L.1
  • 29
    • 77955595254 scopus 로고    scopus 로고
    • Brain function in carriers of a genome-wide supported bipolar disorder variant
    • PID: 20679588
    • Erk S et al. Brain function in carriers of a genome-wide supported bipolar disorder variant. Arch Gen Psychiatry. 2010;67(8):803–11.
    • (2010) Arch Gen Psychiatry , vol.67 , Issue.8 , pp. 803-811
    • Erk, S.1
  • 30
    • 84920269428 scopus 로고    scopus 로고
    • Hippocampal and frontolimbic function as intermediate phenotype for psychosis: evidence from healthy relatives and a common risk variant in CACNA1C
    • Erk, S., et al., Hippocampal and frontolimbic function as intermediate phenotype for psychosis: evidence from healthy relatives and a common risk variant in CACNA1C. Biol Psychiatry, 2013.
    • (2013) Biol Psychiatry
    • Erk, S.1
  • 31
    • 84898647391 scopus 로고    scopus 로고
    • Replication of brain function effects of a genome-wide supported psychiatric risk variant in the CACNA1C gene and new multi-locus effects
    • PID: 24642287, COI: 1:CAS:528:DC%2BC2cXosFWitr4%3D
    • Erk S et al. Replication of brain function effects of a genome-wide supported psychiatric risk variant in the CACNA1C gene and new multi-locus effects. Neuroimage. 2014;94:147–54.
    • (2014) Neuroimage , vol.94 , pp. 147-154
    • Erk, S.1
  • 32
    • 33845348623 scopus 로고    scopus 로고
    • What is familial about familial bipolar disorder? Resemblance among relatives across a broad spectrum of phenotypic characteristics
    • PID: 17146011
    • Schulze TG et al. What is familial about familial bipolar disorder? Resemblance among relatives across a broad spectrum of phenotypic characteristics. Arch Gen Psychiatry. 2006;63(12):1368–76.
    • (2006) Arch Gen Psychiatry , vol.63 , Issue.12 , pp. 1368-1376
    • Schulze, T.G.1
  • 33
    • 34548089960 scopus 로고    scopus 로고
    • The bipolar disorder phenome database: a resource for genetic studies
    • PID: 17671286
    • Potash JB et al. The bipolar disorder phenome database: a resource for genetic studies. Am J Psychiatry. 2007;164(8):1229–37.
    • (2007) Am J Psychiatry , vol.164 , Issue.8 , pp. 1229-1237
    • Potash, J.B.1
  • 34
    • 84859001540 scopus 로고    scopus 로고
    • A genome-wide association study of attempted suicide
    • PID: 21423239, COI: 1:CAS:528:DC%2BC38Xks1ygsr4%3D
    • Willour VL et al. A genome-wide association study of attempted suicide. Mol Psychiatry. 2012;17(4):433–44.
    • (2012) Mol Psychiatry , vol.17 , Issue.4 , pp. 433-444
    • Willour, V.L.1
  • 35
    • 33847274113 scopus 로고    scopus 로고
    • Mood-incongruent psychotic features in bipolar disorder: familial aggregation and suggestive linkage to 2p11-q14 and 13q21-33
    • PID: 17267786
    • Goes FS et al. Mood-incongruent psychotic features in bipolar disorder: familial aggregation and suggestive linkage to 2p11-q14 and 13q21-33. Am J Psychiatry. 2007;164(2):236–47.
    • (2007) Am J Psychiatry , vol.164 , Issue.2 , pp. 236-247
    • Goes, F.S.1
  • 36
    • 0036133633 scopus 로고    scopus 로고
    • Sibling pairs with affective disorders: resemblance of demographic and clinical features
    • PID: 11883730
    • O'Mahony E et al. Sibling pairs with affective disorders: resemblance of demographic and clinical features. Psychol Med. 2002;32(1):55–61.
    • (2002) Psychol Med , vol.32 , Issue.1 , pp. 55-61
    • O'Mahony, E.1
  • 37
    • 0034890445 scopus 로고    scopus 로고
    • The familial aggregation of psychotic symptoms in bipolar disorder pedigrees
    • PID: 11481160, COI: 1:STN:280:DC%2BD3MvjtlGhtA%3D%3D
    • Potash JB et al. The familial aggregation of psychotic symptoms in bipolar disorder pedigrees. Am J Psychiatry. 2001;158(8):1258–64.
    • (2001) Am J Psychiatry , vol.158 , Issue.8 , pp. 1258-1264
    • Potash, J.B.1
  • 38
    • 79952576606 scopus 로고    scopus 로고
    • Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder
    • PID: 21305692
    • Belmonte Mahon P et al. Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2011;156B(3):370–8.
    • (2011) Am J Med Genet B Neuropsychiatr Genet , vol.156B , Issue.3 , pp. 370-378
    • Belmonte Mahon, P.1
  • 39
    • 79953703116 scopus 로고    scopus 로고
    • Polygenic dissection of the bipolar phenotype
    • PID: 21972277, COI: 1:STN:280:DC%2BC3Mfos1Kkuw%3D%3D
    • Hamshere ML et al. Polygenic dissection of the bipolar phenotype. Br J Psychiatry. 2011;198(4):284–8.
    • (2011) Br J Psychiatry , vol.198 , Issue.4 , pp. 284-288
    • Hamshere, M.L.1
  • 40
    • 84874177687 scopus 로고    scopus 로고
    • Genome-wide association of mood-incongruent psychotic bipolar disorder
    • PID: 23092984, COI: 1:STN:280:DC%2BC3s%2Fns1eltg%3D%3D
    • Goes FS et al. Genome-wide association of mood-incongruent psychotic bipolar disorder. Transl Psychiatry. 2012;2:e180.
    • (2012) Transl Psychiatry , vol.2 , pp. e180
    • Goes, F.S.1
  • 41
    • 84883465830 scopus 로고    scopus 로고
    • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
    • Cross-Disorder Group of the Psychiatric Genomics Consortium. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet. 2013;45(9):984–94.
    • (2013) Nat Genet , vol.45 , Issue.9 , pp. 984-994
    • Cross-Disorder Group of the Psychiatric Genomics Consortium1
  • 42
    • 84876296688 scopus 로고    scopus 로고
    • Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
    • Cross-Disorder Group of the Psychiatric Genomics Consortium and Consortium for Genetic Risk Outcome of Psychosis. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet
    • Cross-Disorder Group of the Psychiatric Genomics Consortium and Consortium for Genetic Risk Outcome of Psychosis. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet. 2013;381(9875):1371–9.
    • (2013) Lancet , vol.381 , Issue.9875 , pp. 1371-1379
  • 43
    • 84875166630 scopus 로고    scopus 로고
    • The ANK3 bipolar disorder gene regulates psychiatric-related behaviors that are modulated by lithium and stress
    • PID: 23237312, COI: 1:CAS:528:DC%2BC38XhvVais7rO, Interesting example of examination of the function of a GWAS-implicated BPD gene in an animal model
    • Leussis MP et al. The ANK3 bipolar disorder gene regulates psychiatric-related behaviors that are modulated by lithium and stress. Biol Psychiatry. 2013;73(7):683–90. Interesting example of examination of the function of a GWAS-implicated BPD gene in an animal model.
    • (2013) Biol Psychiatry , vol.73 , Issue.7 , pp. 683-690
    • Leussis, M.P.1
  • 44
    • 84924744563 scopus 로고    scopus 로고
    • Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of beta-catenin
    • PID: 24821222
    • Durak O et al. Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of beta-catenin. Mol Psychiatry. 2014. doi:10.1038/mp.2014.42.
    • (2014) Mol Psychiatry
    • Durak, O.1
  • 45
    • 62849092230 scopus 로고    scopus 로고
    • Singleton deletions throughout the genome increase risk of bipolar disorder
    • PID: 19114987, COI: 1:CAS:528:DC%2BD1MXjsV2gs7g%3D
    • Zhang D et al. Singleton deletions throughout the genome increase risk of bipolar disorder. Mol Psychiatry. 2009;14(4):376–80.
    • (2009) Mol Psychiatry , vol.14 , Issue.4 , pp. 376-380
    • Zhang, D.1
  • 46
    • 77950587223 scopus 로고    scopus 로고
    • Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia
    • PID: 20368508
    • Grozeva D et al. Rare copy number variants: a point of rarity in genetic risk for bipolar disorder and schizophrenia. Arch Gen Psychiatry. 2010;67(4):318–27.
    • (2010) Arch Gen Psychiatry , vol.67 , Issue.4 , pp. 318-327
    • Grozeva, D.1
  • 47
    • 84155191408 scopus 로고    scopus 로고
    • High frequencies of de novo CNVs in bipolar disorder and schizophrenia
    • PID: 22196331, COI: 1:CAS:528:DC%2BC3MXhs1yrsLzJ
    • Malhotra D et al. High frequencies of de novo CNVs in bipolar disorder and schizophrenia. Neuron. 2011;72(6):951–63.
    • (2011) Neuron , vol.72 , Issue.6 , pp. 951-963
    • Malhotra, D.1
  • 48
    • 84866358306 scopus 로고    scopus 로고
    • Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder
    • PID: 22688191, COI: 1:CAS:528:DC%2BC38Xht1GitL3K
    • Bergen SE et al. Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder. Mol Psychiatry. 2012;17(9):880–6.
    • (2012) Mol Psychiatry , vol.17 , Issue.9 , pp. 880-886
    • Bergen, S.E.1
  • 49
    • 84936764234 scopus 로고    scopus 로고
    • De novo CNVs in bipolar affective disorder and schizophrenia, Hum Mol Genet:
    • Georgieva, L., et al., De novo CNVs in bipolar affective disorder and schizophrenia. Hum Mol Genet. 2014.
    • (2014) et al.
    • Georgieva, L.1
  • 50
    • 84873493453 scopus 로고    scopus 로고
    • A hybrid likelihood model for sequence-based disease association studies
    • PID: 23358228, COI: 1:CAS:528:DC%2BC3sXivVehur0%3D
    • Chen YC et al. A hybrid likelihood model for sequence-based disease association studies. PLoS Genet. 2013;9(1):e1003224.
    • (2013) PLoS Genet , vol.9 , Issue.1 , pp. e1003224
    • Chen, Y.C.1
  • 51
    • 84889864585 scopus 로고    scopus 로고
    • Family-based exome-sequencing approach identifies rare susceptibility variants for lithium-responsive bipolar disorder
    • PID: 24237345, COI: 1:CAS:528:DC%2BC3sXhsVKgtbbN
    • Cruceanu C et al. Family-based exome-sequencing approach identifies rare susceptibility variants for lithium-responsive bipolar disorder. Genome. 2013;56(10):634–40.
    • (2013) Genome , vol.56 , Issue.10 , pp. 634-640
    • Cruceanu, C.1
  • 52
    • 84897466223 scopus 로고    scopus 로고
    • Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate
    • PID: 24625924
    • Georgi B et al. Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate. PLoS Genet. 2014;10(3):e1004229.
    • (2014) PLoS Genet , vol.10 , Issue.3 , pp. e1004229
    • Georgi, B.1
  • 53
    • 85027920560 scopus 로고    scopus 로고
    • Analysis of ANK3 and CACNA1C variants identified in bipolar disorder whole genome sequence data
    • PID: 24716743
    • Fiorentino A et al. Analysis of ANK3 and CACNA1C variants identified in bipolar disorder whole genome sequence data. Bipolar Disord. 2014. doi:10.1111/bdi.12203.
    • (2014) Bipolar Disord
    • Fiorentino, A.1
  • 54
    • 84908553599 scopus 로고    scopus 로고
    • RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder
    • PID: 24393808
    • Akula N et al. RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder. Mol Psychiatry. 2014. doi:10.1038/mp.2013.170.
    • (2014) Mol Psychiatry
    • Akula, N.1
  • 55
    • 84899733036 scopus 로고    scopus 로고
    • The DNA methylome and transcriptome of different brain regions in schizophrenia and bipolar disorder
    • PID: 24776767
    • Xiao Y et al. The DNA methylome and transcriptome of different brain regions in schizophrenia and bipolar disorder. PLoS ONE. 2014;9(4):e95875.
    • (2014) PLoS ONE , vol.9 , Issue.4 , pp. e95875
    • Xiao, Y.1
  • 56
    • 33645009013 scopus 로고    scopus 로고
    • Clinical correlates and familial aggregation of age at onset in bipolar disorder
    • PID: 16449477
    • Lin PI et al. Clinical correlates and familial aggregation of age at onset in bipolar disorder. Am J Psychiatry. 2006;163(2):240–6.
    • (2006) Am J Psychiatry , vol.163 , Issue.2 , pp. 240-246
    • Lin, P.I.1
  • 57
    • 79954499505 scopus 로고    scopus 로고
    • Comprehensive DNA methylation analysis of human peripheral blood leukocytes and lymphoblastoid cell lines
    • PID: 21304276, COI: 1:CAS:528:DC%2BC38XhtVCrurw%3D
    • Sugawara H et al. Comprehensive DNA methylation analysis of human peripheral blood leukocytes and lymphoblastoid cell lines. Epigenetics. 2011;6(4):508–15.
    • (2011) Epigenetics , vol.6 , Issue.4 , pp. 508-515
    • Sugawara, H.1
  • 58
    • 84862776228 scopus 로고    scopus 로고
    • A multi-tissue analysis identifies HLA complex group 9 gene methylation differences in bipolar disorder
    • PID: 21647149, COI: 1:CAS:528:DC%2BC38XptF2gsLg%3D
    • Kaminsky Z et al. A multi-tissue analysis identifies HLA complex group 9 gene methylation differences in bipolar disorder. Mol Psychiatry. 2012;17(7):728–40.
    • (2012) Mol Psychiatry , vol.17 , Issue.7 , pp. 728-740
    • Kaminsky, Z.1
  • 59
    • 79960332723 scopus 로고    scopus 로고
    • Increased DNA methylation status of the serotonin receptor 5HTR1A gene promoter in schizophrenia and bipolar disorder
    • PID: 21453976, COI: 1:CAS:528:DC%2BC3MXovFOisrg%3D
    • Carrard A et al. Increased DNA methylation status of the serotonin receptor 5HTR1A gene promoter in schizophrenia and bipolar disorder. J Affect Disord. 2011;132(3):450–3.
    • (2011) J Affect Disord , vol.132 , Issue.3 , pp. 450-453
    • Carrard, A.1
  • 60
    • 80053988998 scopus 로고    scopus 로고
    • DNA hypomethylation of MB-COMT promoter in the DNA derived from saliva in schizophrenia and bipolar disorder
    • PID: 21820670
    • Nohesara S et al. DNA hypomethylation of MB-COMT promoter in the DNA derived from saliva in schizophrenia and bipolar disorder. J Psychiatr Res. 2011;45(11):1432–8.
    • (2011) J Psychiatr Res , vol.45 , Issue.11 , pp. 1432-1438
    • Nohesara, S.1
  • 61
    • 79958714505 scopus 로고    scopus 로고
    • Hypomethylation of the serotonin receptor type-2A Gene (HTR2A) at T102C polymorphic site in DNA derived from the saliva of patients with schizophrenia and bipolar disorder
    • PID: 21598376
    • Ghadirivasfi M et al. Hypomethylation of the serotonin receptor type-2A Gene (HTR2A) at T102C polymorphic site in DNA derived from the saliva of patients with schizophrenia and bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2011;156B(5):536–45.
    • (2011) Am J Med Genet B Neuropsychiatr Genet , vol.156B , Issue.5 , pp. 536-545
    • Ghadirivasfi, M.1
  • 62
    • 79958009147 scopus 로고    scopus 로고
    • Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder
    • PID: 21550210
    • Abdolmaleky HM et al. Epigenetic dysregulation of HTR2A in the brain of patients with schizophrenia and bipolar disorder. Schizophr Res. 2011;129(2–3):183–90.
    • (2011) Schizophr Res , vol.129 , Issue.2-3 , pp. 183-190
    • Abdolmaleky, H.M.1
  • 63
    • 33750244045 scopus 로고    scopus 로고
    • Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder
    • PID: 16984965, COI: 1:CAS:528:DC%2BD28XhtFaktrvN
    • Abdolmaleky HM et al. Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder. Hum Mol Genet. 2006;15(21):3132–45.
    • (2006) Hum Mol Genet , vol.15 , Issue.21 , pp. 3132-3145
    • Abdolmaleky, H.M.1
  • 64
    • 81855183787 scopus 로고    scopus 로고
    • Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder
    • PID: 21908516, COI: 1:CAS:528:DC%2BC3MXhsV2gsL7J
    • Dempster EL et al. Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder. Hum Mol Genet. 2011;20(24):4786–96.
    • (2011) Hum Mol Genet , vol.20 , Issue.24 , pp. 4786-4796
    • Dempster, E.L.1
  • 65
    • 41149140859 scopus 로고    scopus 로고
    • Epigenomic profiling reveals DNA-methylation changes associated with major psychosis
    • PID: 18319075, COI: 1:CAS:528:DC%2BD1cXksVGrtbY%3D
    • Mill J et al. Epigenomic profiling reveals DNA-methylation changes associated with major psychosis. Am J Hum Genet. 2008;82(3):696–711.
    • (2008) Am J Hum Genet , vol.82 , Issue.3 , pp. 696-711
    • Mill, J.1
  • 66
    • 84871664677 scopus 로고    scopus 로고
    • Neuronal cell-type specific DNA methylation patterns of the Cacna1c gene
    • PID: 23183239, COI: 1:CAS:528:DC%2BC3sXhsVOkurs%3D
    • Nishioka M et al. Neuronal cell-type specific DNA methylation patterns of the Cacna1c gene. Int J Dev Neurosci. 2013;31(2):89–95.
    • (2013) Int J Dev Neurosci , vol.31 , Issue.2 , pp. 89-95
    • Nishioka, M.1
  • 67
    • 0036773679 scopus 로고    scopus 로고
    • Is response to prophylactic lithium a familial trait?
    • PID: 12416605, COI: 1:CAS:528:DC%2BD38Xosl2qsbo%3D
    • Grof P et al. Is response to prophylactic lithium a familial trait? J Clin Psychiatry. 2002;63(10):942–7.
    • (2002) J Clin Psychiatry , vol.63 , Issue.10 , pp. 942-947
    • Grof, P.1
  • 68
    • 66949165513 scopus 로고    scopus 로고
    • A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder
    • PID: 19448189
    • Perlis RH et al. A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder. Am J Psychiatry. 2009;166(6):718–25.
    • (2009) Am J Psychiatry , vol.166 , Issue.6 , pp. 718-725
    • Perlis, R.H.1
  • 69
    • 84892604542 scopus 로고    scopus 로고
    • Variant GADL1 and response to lithium therapy in bipolar I disorder
    • PID: 24369049, COI: 1:CAS:528:DC%2BC2cXotlKrsA%3D%3D, High profile paper suggests that a single SNP determines lithium response in East Asians
    • Chen CH et al. Variant GADL1 and response to lithium therapy in bipolar I disorder. N Engl J Med. 2014;370(2):119–28. High profile paper suggests that a single SNP determines lithium response in East Asians.
    • (2014) N Engl J Med , vol.370 , Issue.2 , pp. 119-128
    • Chen, C.H.1
  • 70
    • 84899840543 scopus 로고    scopus 로고
    • Variant GADL1 and response to lithium in bipolar I disorder
    • PID: 24806175, A failure to replicate the high profile Chen et al. result
    • Ikeda M, Kondo K, Iwata N. Variant GADL1 and response to lithium in bipolar I disorder. N Engl J Med. 2014;370(19):1856–7. A failure to replicate the high profile Chen et al. result.
    • (2014) N Engl J Med , vol.370 , Issue.19 , pp. 1856-1857
    • Ikeda, M.1    Kondo, K.2    Iwata, N.3
  • 71
    • 84899802026 scopus 로고    scopus 로고
    • Consortium on Lithium Genetics., et al., Variant GADL1 and response to lithium in bipolar I disorder. N Engl J Med, 2014. 370(19):1857–9. A failure to replicate the high profile Chen et al. result
    • Consortium on Lithium Genetics., et al., Variant GADL1 and response to lithium in bipolar I disorder. N Engl J Med, 2014. 370(19):1857–9. A failure to replicate the high profile Chen et al. result.
  • 72


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