Copper exposure induces toxicity to the antioxidant system via the destruction of Nrf2/ARE signaling and caspase-3-regulated DNA damage in fish muscle: Amelioration by myo-inositol

Aquatic Toxicology

Volumn 159, Issue , 2015, Pages 245-255

  Jiang, Wei Dan ^a   Liu, Yang ^a   Jiang, Jun ^a   Wu, Pei ^a   Feng, Lin ^a   Zhou, Xiao Qiu ^a  

^a SICHUAN AGRICULTURAL UNIVERSITY   (China)

Author keywords

Carp; Copper; DNA fragmentation; Muscle; Myo Inositol; Nrf2

Indexed keywords

CASPASE 3; COPPER; COPPER ZINC SUPEROXIDE DISMUTASE; DNA; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE PEROXIDASE 1A; GLUTATHIONE PEROXIDASE 1B; INOSITOL; MESSENGER RNA; PROTEIN KINASE C DELTA; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; OXIDOREDUCTASE; PROTEIN BINDING; WATER POLLUTANT;

ANTIOXIDANT; COPPER; CYPRINID; DNA; ENZYME ACTIVITY; MUSCLE; TOXICITY;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DNA DAMAGE; DNA FRAGMENTATION; DOWN REGULATION; ECOTOXICITY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVITY; FISH; GENE EXPRESSION; LIPID PEROXIDATION; MUSCLE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTECTION; SIGNAL TRANSDUCTION; ANIMAL; CARP; DRUG EFFECTS; ENZYME ACTIVATION; METABOLISM; OXIDATION REDUCTION REACTION; PHYSIOLOGY; SKELETAL MUSCLE; TOXICITY; WATER POLLUTANT;

CYPRINIDAE;

ANIMALS; ANTIOXIDANT RESPONSE ELEMENTS; CARPS; CASPASE 3; COPPER; DNA DAMAGE; DOWN-REGULATION; ENZYME ACTIVATION; GLUTATHIONE; INOSITOL; LIPID PEROXIDATION; MUSCLE, SKELETAL; NF-E2-RELATED FACTOR 2; OXIDATION-REDUCTION; OXIDATIVE STRESS; OXIDOREDUCTASES; PROTEIN BINDING; SIGNAL TRANSDUCTION; WATER POLLUTANTS, CHEMICAL;

EID: 84920279700     PISSN: 0166445X     EISSN: 18791514     Source Type: Journal    
DOI: 10.1016/j.aquatox.2014.12.020     Document Type: Article

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