Internalization and stability of a thymidylate synthase peptide inhibitor in ovarian cancer cells

Journal of Medicinal Chemistry

Volumn 57, Issue 24, 2014, Pages 10551-10556

  Cannazza, Giuseppe ^a   Cazzato, Addolorata Stefania ^a   Marraccini, Chiara ^a   Pavesi, Giorgia ^a   Pirondi, Silvia ^a   Guerrini, Remo ^b   Pelà, Michela ^b   Frassineti, Chiara ^a   Ferrari, Stefania ^a   Marverti, Gaetano ^a   Ponterini, Glauco ^a   Costi, Maria Paola ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; THIOL; THYMIDYLATE SYNTHASE INHIBITOR; ENZYME INHIBITOR; PEPTIDE FRAGMENT; THYMIDYLATE SYNTHASE;

ARTICLE; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG STABILITY; DRUG STRUCTURE; INTERNALIZATION; MASS SPECTROMETRY; OVARIAN CANCER CELL LINE; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; CONFOCAL MICROSCOPY; DRUG EFFECTS; ENZYMOLOGY; FEMALE; FLUORESCENCE; HUMAN; OVARIAN NEOPLASMS; TANDEM MASS SPECTROMETRY; TUMOR CELL CULTURE;

CELL PROLIFERATION; ENZYME INHIBITORS; FEMALE; FLUORESCENCE; HUMANS; MICROSCOPY, CONFOCAL; MOLECULAR STRUCTURE; OVARIAN NEOPLASMS; PEPTIDE FRAGMENTS; TANDEM MASS SPECTROMETRY; THYMIDYLATE SYNTHASE; TUMOR CELLS, CULTURED;

EID: 84920109615     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm501397h     Document Type: Article

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