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Volumn 26, Issue 6, 2014, Pages 543-551

Pro-and anti-inflammatory cytokines in tuberculosis: A two-edged sword in TB pathogenesis

Author keywords

Cytokine network; Cytokines; Danger signal; Immunoregulation; Mtb infection

Indexed keywords

CYTOKINE;

EID: 84920001803     PISSN: 10445323     EISSN: 10963618     Source Type: Journal    
DOI: 10.1016/j.smim.2014.09.011     Document Type: Review
Times cited : (136)

References (109)
  • 3
    • 72849108071 scopus 로고    scopus 로고
    • Dectin-1 is inducible and plays an essential role for mycobacteria-induced innate immune responses in airway epithelial cells
    • Lee H.M., Yuk J.M., Shin D.M., Jo E.K. Dectin-1 is inducible and plays an essential role for mycobacteria-induced innate immune responses in airway epithelial cells. J Clin Immunol 2009, 29:795-805.
    • (2009) J Clin Immunol , vol.29 , pp. 795-805
    • Lee, H.M.1    Yuk, J.M.2    Shin, D.M.3    Jo, E.K.4
  • 4
    • 34247899005 scopus 로고    scopus 로고
    • Pulmonary epithelial cells are a source of interferon-gamma in response to Mycobacterium tuberculosis infection
    • Sharma M., Sharma S., Roy S., Varma S., Bose M. Pulmonary epithelial cells are a source of interferon-gamma in response to Mycobacterium tuberculosis infection. Immunol Cell Biol 2007, 85:229-237.
    • (2007) Immunol Cell Biol , vol.85 , pp. 229-237
    • Sharma, M.1    Sharma, S.2    Roy, S.3    Varma, S.4    Bose, M.5
  • 5
    • 3042752919 scopus 로고    scopus 로고
    • Induction of nitric oxide release from the human alveolar epithelial cell line A549: an in vitro correlate of innate immune response to Mycobacterium tuberculosis
    • Roy S., Sharma S., Sharma M., Aggarwal R., Bose M. Induction of nitric oxide release from the human alveolar epithelial cell line A549: an in vitro correlate of innate immune response to Mycobacterium tuberculosis. Immunology 2004, 112:471-480.
    • (2004) Immunology , vol.112 , pp. 471-480
    • Roy, S.1    Sharma, S.2    Sharma, M.3    Aggarwal, R.4    Bose, M.5
  • 6
    • 84864357703 scopus 로고    scopus 로고
    • The immunological life cycle of tuberculosis
    • Ernst J.D. The immunological life cycle of tuberculosis. Nat Rev Immunol 2012, 12:581-591.
    • (2012) Nat Rev Immunol , vol.12 , pp. 581-591
    • Ernst, J.D.1
  • 7
    • 84905397678 scopus 로고    scopus 로고
    • The T-cell response to lipid antigens of Mycobacterium tuberculosis
    • De Libero G., Mori L. The T-cell response to lipid antigens of Mycobacterium tuberculosis. Front Immunol 2014, 5:219.
    • (2014) Front Immunol , vol.5 , pp. 219
    • De Libero, G.1    Mori, L.2
  • 9
    • 64049113596 scopus 로고    scopus 로고
    • How B cells shape the immune response against Mycobacterium tuberculosis
    • Maglione P.J., Chan J. How B cells shape the immune response against Mycobacterium tuberculosis. Eur J Immunol 2009, 39:676-686.
    • (2009) Eur J Immunol , vol.39 , pp. 676-686
    • Maglione, P.J.1    Chan, J.2
  • 10
    • 84875141413 scopus 로고    scopus 로고
    • Antibody-mediated immunity against tuberculosis: implications for vaccine development
    • Achkar J.M., Casadevall A. Antibody-mediated immunity against tuberculosis: implications for vaccine development. Cell Host Microbe 2013, 13:250-262.
    • (2013) Cell Host Microbe , vol.13 , pp. 250-262
    • Achkar, J.M.1    Casadevall, A.2
  • 12
    • 34047262879 scopus 로고    scopus 로고
    • Intracellular signalling cascades regulating innate immune responses to Mycobacteria: branching out from Toll-like receptors
    • Jo E.K., Yang C.S., Choi C.H., Harding C.V. Intracellular signalling cascades regulating innate immune responses to Mycobacteria: branching out from Toll-like receptors. Cell Microbiol 2007, 9:1087-1098.
    • (2007) Cell Microbiol , vol.9 , pp. 1087-1098
    • Jo, E.K.1    Yang, C.S.2    Choi, C.H.3    Harding, C.V.4
  • 13
    • 84856843927 scopus 로고    scopus 로고
    • Tuberculosis pathogenesis and immunity
    • Philips J.A., Ernst J.D. Tuberculosis pathogenesis and immunity. Annu Rev Pathol 2012, 7:353-384.
    • (2012) Annu Rev Pathol , vol.7 , pp. 353-384
    • Philips, J.A.1    Ernst, J.D.2
  • 14
    • 80052345448 scopus 로고    scopus 로고
    • A delicate dance: host response to mycobacteria
    • Huynh K.K., Joshi S.A., Brown E.J. A delicate dance: host response to mycobacteria. Curr Opin Immunol 2011, 23:464-472.
    • (2011) Curr Opin Immunol , vol.23 , pp. 464-472
    • Huynh, K.K.1    Joshi, S.A.2    Brown, E.J.3
  • 16
    • 79955110091 scopus 로고    scopus 로고
    • Role of innate cytokines in mycobacterial infection
    • Cooper A.M., Mayer-Barber K.D., Sher A. Role of innate cytokines in mycobacterial infection. Mucosal Immunol 2011, 4:252-260.
    • (2011) Mucosal Immunol , vol.4 , pp. 252-260
    • Cooper, A.M.1    Mayer-Barber, K.D.2    Sher, A.3
  • 17
    • 0037090054 scopus 로고    scopus 로고
    • Type II alveolar cells play roles in macrophage-mediated host innate resistance to pulmonary mycobacterial infections by producing proinflammatory cytokines
    • Sato K., Tomioka H., Shimizu T., Gonda T., Ota F., Sano C. Type II alveolar cells play roles in macrophage-mediated host innate resistance to pulmonary mycobacterial infections by producing proinflammatory cytokines. J Infect Dis 2002, 185:1139-1147.
    • (2002) J Infect Dis , vol.185 , pp. 1139-1147
    • Sato, K.1    Tomioka, H.2    Shimizu, T.3    Gonda, T.4    Ota, F.5    Sano, C.6
  • 18
    • 84901312544 scopus 로고    scopus 로고
    • Human lung epithelial cells contain Mycobacterium tuberculosis in a late endosomal vacuole and are efficiently recognized by CD8(+) T cells
    • Harriff M.J., Cansler M.E., Toren K.G., Canfield E.T., Kwak S., Gold M.C., et al. Human lung epithelial cells contain Mycobacterium tuberculosis in a late endosomal vacuole and are efficiently recognized by CD8(+) T cells. PLOS ONE 2014, 9:e97515.
    • (2014) PLOS ONE , vol.9 , pp. e97515
    • Harriff, M.J.1    Cansler, M.E.2    Toren, K.G.3    Canfield, E.T.4    Kwak, S.5    Gold, M.C.6
  • 19
    • 0033213894 scopus 로고    scopus 로고
    • Pulmonary epithelial cells are a source of IL-8 in the response to Mycobacterium tuberculosis: essential role of IL-1 from infected monocytes in a NF-kappa B-dependent network
    • Wickremasinghe M.I., Thomas L.H., Friedland J.S. Pulmonary epithelial cells are a source of IL-8 in the response to Mycobacterium tuberculosis: essential role of IL-1 from infected monocytes in a NF-kappa B-dependent network. J Immunol 1999, 163:3936-3947.
    • (1999) J Immunol , vol.163 , pp. 3936-3947
    • Wickremasinghe, M.I.1    Thomas, L.H.2    Friedland, J.S.3
  • 20
    • 33947220885 scopus 로고    scopus 로고
    • Monocyte-dependent fibroblast CXCL8 secretion occurs in tuberculosis and limits survival of mycobacteria within macrophages
    • O'Kane C.M., Boyle J.J., Horncastle D.E., Elkington P.T., Friedland J.S. Monocyte-dependent fibroblast CXCL8 secretion occurs in tuberculosis and limits survival of mycobacteria within macrophages. J Immunol 2007, 178:3767-3776.
    • (2007) J Immunol , vol.178 , pp. 3767-3776
    • O'Kane, C.M.1    Boyle, J.J.2    Horncastle, D.E.3    Elkington, P.T.4    Friedland, J.S.5
  • 21
    • 40949164333 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis-induced apoptotic neutrophils trigger a pro-inflammatory response in macrophages through release of heat shock protein 72, acting in synergy with the bacteria
    • Persson Y.A., Blomgran-Julinder R., Rahman S., Zheng L., Stendahl O. Mycobacterium tuberculosis-induced apoptotic neutrophils trigger a pro-inflammatory response in macrophages through release of heat shock protein 72, acting in synergy with the bacteria. Microbes Infect 2008, 10:233-240.
    • (2008) Microbes Infect , vol.10 , pp. 233-240
    • Persson, Y.A.1    Blomgran-Julinder, R.2    Rahman, S.3    Zheng, L.4    Stendahl, O.5
  • 22
    • 33748522053 scopus 로고    scopus 로고
    • Clearance of apoptotic and necrotic cells and its immunological consequences
    • Krysko D.V., D'Herde K., Vandenabeele P. Clearance of apoptotic and necrotic cells and its immunological consequences. Apoptosis 2006, 11:1709-1726.
    • (2006) Apoptosis , vol.11 , pp. 1709-1726
    • Krysko, D.V.1    D'Herde, K.2    Vandenabeele, P.3
  • 23
    • 79959564980 scopus 로고    scopus 로고
    • Lung neutrophils facilitate activation of naive antigen-specific CD4+ T cells during Mycobacterium tuberculosis infection
    • Blomgran R., Ernst J.D. Lung neutrophils facilitate activation of naive antigen-specific CD4+ T cells during Mycobacterium tuberculosis infection. J Immunol 2011, 186:7110-7119.
    • (2011) J Immunol , vol.186 , pp. 7110-7119
    • Blomgran, R.1    Ernst, J.D.2
  • 24
    • 79960829290 scopus 로고    scopus 로고
    • Neutrophils in the activation and regulation of innate and adaptive immunity
    • Mantovani A., Cassatella M.A., Costantini C., Jaillon S. Neutrophils in the activation and regulation of innate and adaptive immunity. Nat Rev Immunol 2011, 11:519-531.
    • (2011) Nat Rev Immunol , vol.11 , pp. 519-531
    • Mantovani, A.1    Cassatella, M.A.2    Costantini, C.3    Jaillon, S.4
  • 25
    • 84856003520 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis inhibits neutrophil apoptosis, leading to delayed activation of naive CD4T cells
    • Blomgran R., Desvignes L., Briken V., Ernst J.D. Mycobacterium tuberculosis inhibits neutrophil apoptosis, leading to delayed activation of naive CD4T cells. Cell Host Microbe 2012, 11:81-90.
    • (2012) Cell Host Microbe , vol.11 , pp. 81-90
    • Blomgran, R.1    Desvignes, L.2    Briken, V.3    Ernst, J.D.4
  • 26
    • 84934437018 scopus 로고    scopus 로고
    • Vita-PAMPs: signatures of microbial viability
    • Mourao-Sa D., Roy S., Blander J.M. Vita-PAMPs: signatures of microbial viability. Adv Exp Med Biol 2013, 785:1-8.
    • (2013) Adv Exp Med Biol , vol.785 , pp. 1-8
    • Mourao-Sa, D.1    Roy, S.2    Blander, J.M.3
  • 27
    • 84893610815 scopus 로고    scopus 로고
    • TLR3 regulates mycobacterial RNA-induced IL-10 production through the PI3K/AKT signaling pathway
    • Bai W., Liu H., Ji Q., Zhou Y., Liang L., Zheng R., et al. TLR3 regulates mycobacterial RNA-induced IL-10 production through the PI3K/AKT signaling pathway. Cell Signal 2014, 26:942-950.
    • (2014) Cell Signal , vol.26 , pp. 942-950
    • Bai, W.1    Liu, H.2    Ji, Q.3    Zhou, Y.4    Liang, L.5    Zheng, R.6
  • 28
    • 0028220231 scopus 로고
    • Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase
    • Sturgill-Koszycki S., Schlesinger P.H., Chakraborty P., Haddix P.L., Collins H.L., Fok A.K., et al. Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase. Science 1994, 263:678-681.
    • (1994) Science , vol.263 , pp. 678-681
    • Sturgill-Koszycki, S.1    Schlesinger, P.H.2    Chakraborty, P.3    Haddix, P.L.4    Collins, H.L.5    Fok, A.K.6
  • 29
    • 60049091769 scopus 로고    scopus 로고
    • ESX/type VII secretion systems and their role in host-pathogen interaction
    • Simeone R., Bottai D., Brosch R. ESX/type VII secretion systems and their role in host-pathogen interaction. Curr Opin Microbiol 2009, 12:4-10.
    • (2009) Curr Opin Microbiol , vol.12 , pp. 4-10
    • Simeone, R.1    Bottai, D.2    Brosch, R.3
  • 30
    • 84887611505 scopus 로고    scopus 로고
    • ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis
    • Aguilo J.I., Alonso H., Uranga S., Marinova D., Arbues A., de Martino A., et al. ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis. Cell Microbiol 2013, 15:1994-2005.
    • (2013) Cell Microbiol , vol.15 , pp. 1994-2005
    • Aguilo, J.I.1    Alonso, H.2    Uranga, S.3    Marinova, D.4    Arbues, A.5    de Martino, A.6
  • 31
    • 84897919780 scopus 로고    scopus 로고
    • ESX-1-induced apoptosis during mycobacterial infection: to be or not to be, that is the question
    • Aguilo N., Marinova D., Martin C., Pardo J. ESX-1-induced apoptosis during mycobacterial infection: to be or not to be, that is the question. Front Cell Infect Microbiol 2013, 3:88.
    • (2013) Front Cell Infect Microbiol , vol.3 , pp. 88
    • Aguilo, N.1    Marinova, D.2    Martin, C.3    Pardo, J.4
  • 33
    • 77954050777 scopus 로고    scopus 로고
    • Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection
    • Carlsson F., Kim J., Dumitru C., Barck K.H., Carano R.A., Sun M., et al. Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection. PLoS Pathog 2010, 6:e1000895.
    • (2010) PLoS Pathog , vol.6 , pp. e1000895
    • Carlsson, F.1    Kim, J.2    Dumitru, C.3    Barck, K.H.4    Carano, R.A.5    Sun, M.6
  • 34
    • 48749097539 scopus 로고    scopus 로고
    • ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection
    • Koo I.C., Wang C., Raghavan S., Morisaki J.H., Cox J.S., Brown E.J. ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection. Cell Microbiol 2008, 10:1866-1878.
    • (2008) Cell Microbiol , vol.10 , pp. 1866-1878
    • Koo, I.C.1    Wang, C.2    Raghavan, S.3    Morisaki, J.H.4    Cox, J.S.5    Brown, E.J.6
  • 35
    • 84865220380 scopus 로고    scopus 로고
    • Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway
    • Watson R.O., Manzanillo P.S., Cox J.S. Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway. Cell 2012, 150:803-815.
    • (2012) Cell , vol.150 , pp. 803-815
    • Watson, R.O.1    Manzanillo, P.S.2    Cox, J.S.3
  • 37
    • 84897919055 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis and the host cell inflammasome: a complex relationship
    • Briken V., Ahlbrand S.E., Shah S. Mycobacterium tuberculosis and the host cell inflammasome: a complex relationship. Front Cell Infect Microbiol 2013, 3:62.
    • (2013) Front Cell Infect Microbiol , vol.3 , pp. 62
    • Briken, V.1    Ahlbrand, S.E.2    Shah, S.3
  • 38
    • 84890199193 scopus 로고    scopus 로고
    • Host-pathogen interactions during Mycobacterium tuberculosis infections
    • Stanley S.A., Cox J.S. Host-pathogen interactions during Mycobacterium tuberculosis infections. Curr Top Microbiol Immunol 2013, 374:211-241.
    • (2013) Curr Top Microbiol Immunol , vol.374 , pp. 211-241
    • Stanley, S.A.1    Cox, J.S.2
  • 39
    • 79952219528 scopus 로고    scopus 로고
    • Expression of proinflammatory and regulatory cytokines via NF-kappaB and MAPK-dependent and IFN regulatory factor-3-independent mechanisms in human primary monocytes infected by Mycobacterium tuberculosis
    • Giacomini E., Remoli M.E., Scandurra M., Gafa V., Pardini M., Fattorini L., et al. Expression of proinflammatory and regulatory cytokines via NF-kappaB and MAPK-dependent and IFN regulatory factor-3-independent mechanisms in human primary monocytes infected by Mycobacterium tuberculosis. Clin Dev Immunol 2011, 2011:841346.
    • (2011) Clin Dev Immunol , vol.2011 , pp. 841346
    • Giacomini, E.1    Remoli, M.E.2    Scandurra, M.3    Gafa, V.4    Pardini, M.5    Fattorini, L.6
  • 40
    • 0036644594 scopus 로고    scopus 로고
    • Selective expression of type I IFN genes in human dendritic cells infected with Mycobacterium tuberculosis
    • Remoli M.E., Giacomini E., Lutfalla G., Dondi E., Orefici G., Battistini A., et al. Selective expression of type I IFN genes in human dendritic cells infected with Mycobacterium tuberculosis. J Immunol 2002, 169:366-374.
    • (2002) J Immunol , vol.169 , pp. 366-374
    • Remoli, M.E.1    Giacomini, E.2    Lutfalla, G.3    Dondi, E.4    Orefici, G.5    Battistini, A.6
  • 42
    • 84903750131 scopus 로고    scopus 로고
    • Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk
    • Mayer-Barber K.D., Andrade B.B., Oland S.D., Amaral E.P., Barber D.L., Gonzales J., et al. Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk. Nature 2014, 511:99-103.
    • (2014) Nature , vol.511 , pp. 99-103
    • Mayer-Barber, K.D.1    Andrade, B.B.2    Oland, S.D.3    Amaral, E.P.4    Barber, D.L.5    Gonzales, J.6
  • 43
    • 84904042898 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha in mycobacterial infection
    • Dorhoi A., Kaufmann S.H. Tumor necrosis factor alpha in mycobacterial infection. Semin Immunol 2014, 26:203-209.
    • (2014) Semin Immunol , vol.26 , pp. 203-209
    • Dorhoi, A.1    Kaufmann, S.H.2
  • 45
    • 52049124279 scopus 로고    scopus 로고
    • Tumour necrosis factor antagonists: structure, function, and tuberculosis risks
    • Wallis R.S. Tumour necrosis factor antagonists: structure, function, and tuberculosis risks. Lancet Infect Dis 2008, 8:601-611.
    • (2008) Lancet Infect Dis , vol.8 , pp. 601-611
    • Wallis, R.S.1
  • 46
    • 70449502228 scopus 로고    scopus 로고
    • Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils
    • Zhang X., Majlessi L., Deriaud E., Leclerc C., Lo-Man R. Coactivation of Syk kinase and MyD88 adaptor protein pathways by bacteria promotes regulatory properties of neutrophils. Immunity 2009, 31:761-771.
    • (2009) Immunity , vol.31 , pp. 761-771
    • Zhang, X.1    Majlessi, L.2    Deriaud, E.3    Leclerc, C.4    Lo-Man, R.5
  • 47
    • 84867629125 scopus 로고    scopus 로고
    • Natural killer cells are recruited during pulmonary tuberculosis and their ex vivo responses to mycobacteria vary between healthy human donors in association with KIR haplotype
    • Portevin D., Via L.E., Eum S., Young D. Natural killer cells are recruited during pulmonary tuberculosis and their ex vivo responses to mycobacteria vary between healthy human donors in association with KIR haplotype. Cell Microbiol 2012, 14:1734-1744.
    • (2012) Cell Microbiol , vol.14 , pp. 1734-1744
    • Portevin, D.1    Via, L.E.2    Eum, S.3    Young, D.4
  • 48
    • 0035877017 scopus 로고    scopus 로고
    • Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell response
    • Giacomini E., Iona E., Ferroni L., Miettinen M., Fattorini L., Orefici G., et al. Infection of human macrophages and dendritic cells with Mycobacterium tuberculosis induces a differential cytokine gene expression that modulates T cell response. J Immunol 2001, 166:7033-7041.
    • (2001) J Immunol , vol.166 , pp. 7033-7041
    • Giacomini, E.1    Iona, E.2    Ferroni, L.3    Miettinen, M.4    Fattorini, L.5    Orefici, G.6
  • 49
    • 0037307911 scopus 로고    scopus 로고
    • IFN-alpha beta released by Mycobacterium tuberculosis-infected human dendritic cells induces the expression of CXCL10: selective recruitment of NK and activated T cells
    • Lande R., Giacomini E., Grassi T., Remoli M.E., Iona E., Miettinen M., et al. IFN-alpha beta released by Mycobacterium tuberculosis-infected human dendritic cells induces the expression of CXCL10: selective recruitment of NK and activated T cells. J Immunol 2003, 170:1174-1182.
    • (2003) J Immunol , vol.170 , pp. 1174-1182
    • Lande, R.1    Giacomini, E.2    Grassi, T.3    Remoli, M.E.4    Iona, E.5    Miettinen, M.6
  • 50
    • 84866686896 scopus 로고    scopus 로고
    • Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis
    • Ottenhoff T.H., Dass R.H., Yang N., Zhang M.M., Wong H.E., Sahiratmadja E., et al. Genome-wide expression profiling identifies type 1 interferon response pathways in active tuberculosis. PLoS ONE 2012, 7:e45839.
    • (2012) PLoS ONE , vol.7 , pp. e45839
    • Ottenhoff, T.H.1    Dass, R.H.2    Yang, N.3    Zhang, M.M.4    Wong, H.E.5    Sahiratmadja, E.6
  • 51
    • 77955894773 scopus 로고    scopus 로고
    • An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
    • Berry M.P., Graham C.M., McNab F.W., Xu Z., Bloch S.A., Oni T., et al. An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature 2010, 466:973-977.
    • (2010) Nature , vol.466 , pp. 973-977
    • Berry, M.P.1    Graham, C.M.2    McNab, F.W.3    Xu, Z.4    Bloch, S.A.5    Oni, T.6
  • 54
    • 84862601432 scopus 로고    scopus 로고
    • Dynamic roles of type I and type II IFNs in early infection with Mycobacterium tuberculosis
    • Desvignes L., Wolf A.J., Ernst J.D. Dynamic roles of type I and type II IFNs in early infection with Mycobacterium tuberculosis. J Immunol 2012, 188:6205-6215.
    • (2012) J Immunol , vol.188 , pp. 6205-6215
    • Desvignes, L.1    Wolf, A.J.2    Ernst, J.D.3
  • 55
    • 84884179172 scopus 로고    scopus 로고
    • A helicopter perspective on TB biomarkers: pathway and process based analysis of gene expression data provides new insight into TB pathogenesis
    • Joosten S.A., Fletcher H.A., Ottenhoff T.H. A helicopter perspective on TB biomarkers: pathway and process based analysis of gene expression data provides new insight into TB pathogenesis. PLOS ONE 2013, 8:e73230.
    • (2013) PLOS ONE , vol.8 , pp. e73230
    • Joosten, S.A.1    Fletcher, H.A.2    Ottenhoff, T.H.3
  • 56
    • 84866748115 scopus 로고    scopus 로고
    • Mycobacterial disease and impaired IFN-gamma immunity in humans with inherited ISG15 deficiency
    • Bogunovic D., Byun M., Durfee L.A., Abhyankar A., Sanal O., Mansouri D., et al. Mycobacterial disease and impaired IFN-gamma immunity in humans with inherited ISG15 deficiency. Science 2012, 337:1684-1688.
    • (2012) Science , vol.337 , pp. 1684-1688
    • Bogunovic, D.1    Byun, M.2    Durfee, L.A.3    Abhyankar, A.4    Sanal, O.5    Mansouri, D.6
  • 57
    • 84875256111 scopus 로고    scopus 로고
    • Chemokines shape the immune responses to tuberculosis
    • Slight S.R., Khader S.A. Chemokines shape the immune responses to tuberculosis. Cytokine Growth Factor Rev 2013, 24:105-113.
    • (2013) Cytokine Growth Factor Rev , vol.24 , pp. 105-113
    • Slight, S.R.1    Khader, S.A.2
  • 58
    • 68149171688 scopus 로고    scopus 로고
    • T cells in mycobacterial infection and disease
    • Cooper A.M. T cells in mycobacterial infection and disease. Curr Opin Immunol 2009, 21:378-384.
    • (2009) Curr Opin Immunol , vol.21 , pp. 378-384
    • Cooper, A.M.1
  • 59
    • 33745812070 scopus 로고    scopus 로고
    • Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection
    • Khader S.A., Partida-Sanchez S., Bell G., Jelley-Gibbs D.M., Swain S., Pearl J.E., et al. Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection. J Exp Med 2006, 203:1805-1815.
    • (2006) J Exp Med , vol.203 , pp. 1805-1815
    • Khader, S.A.1    Partida-Sanchez, S.2    Bell, G.3    Jelley-Gibbs, D.M.4    Swain, S.5    Pearl, J.E.6
  • 60
    • 23844545821 scopus 로고    scopus 로고
    • In vivo depletion of CD11c+ cells delays the CD4+ T cell response to Mycobacterium tuberculosis and exacerbates the outcome of infection
    • Tian T., Woodworth J., Skold M., Behar S.M. In vivo depletion of CD11c+ cells delays the CD4+ T cell response to Mycobacterium tuberculosis and exacerbates the outcome of infection. J Immunol 2005, 175:3268-3272.
    • (2005) J Immunol , vol.175 , pp. 3268-3272
    • Tian, T.1    Woodworth, J.2    Skold, M.3    Behar, S.M.4
  • 61
    • 38749138163 scopus 로고    scopus 로고
    • Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs
    • Wolf A.J., Desvignes L., Linas B., Banaiee N., Tamura T., Takatsu K., et al. Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs. J Exp Med 2008, 205:105-115.
    • (2008) J Exp Med , vol.205 , pp. 105-115
    • Wolf, A.J.1    Desvignes, L.2    Linas, B.3    Banaiee, N.4    Tamura, T.5    Takatsu, K.6
  • 62
    • 84902466434 scopus 로고    scopus 로고
    • Cell-to-cell transfer of M. tuberculosis antigens optimizes CD4T cell priming
    • Srivastava S., Ernst J.D. Cell-to-cell transfer of M. tuberculosis antigens optimizes CD4T cell priming. Cell Host Microbe 2014, 15:741-752.
    • (2014) Cell Host Microbe , vol.15 , pp. 741-752
    • Srivastava, S.1    Ernst, J.D.2
  • 63
    • 84887786185 scopus 로고    scopus 로고
    • Essential yet limited role for CCR2+ inflammatory monocytes during Mycobacterium tuberculosis-specific T cell priming
    • Samstein M., Schreiber H.A., Leiner I.M., Susac B., Glickman M.S., Pamer E.G. Essential yet limited role for CCR2+ inflammatory monocytes during Mycobacterium tuberculosis-specific T cell priming. eLife 2013, 2:e01086.
    • (2013) eLife , vol.2 , pp. e01086
    • Samstein, M.1    Schreiber, H.A.2    Leiner, I.M.3    Susac, B.4    Glickman, M.S.5    Pamer, E.G.6
  • 64
    • 34547766513 scopus 로고    scopus 로고
    • ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity
    • de Jonge M.I., Pehau-Arnaudet G., Fretz M.M., Romain F., Bottai D., Brodin P., et al. ESAT-6 from Mycobacterium tuberculosis dissociates from its putative chaperone CFP-10 under acidic conditions and exhibits membrane-lysing activity. J Bacteriol 2007, 189:6028-6034.
    • (2007) J Bacteriol , vol.189 , pp. 6028-6034
    • de Jonge, M.I.1    Pehau-Arnaudet, G.2    Fretz, M.M.3    Romain, F.4    Bottai, D.5    Brodin, P.6
  • 65
    • 31544456342 scopus 로고    scopus 로고
    • Interferon regulatory factor 3 is involved in Toll-like receptor 4 (TLR4)- and TLR3-induced IL-12p35 gene activation
    • Goriely S., Molle C., Nguyen M., Albarani V., Haddou N.O., Lin R., et al. Interferon regulatory factor 3 is involved in Toll-like receptor 4 (TLR4)- and TLR3-induced IL-12p35 gene activation. Blood 2006, 107:1078-1084.
    • (2006) Blood , vol.107 , pp. 1078-1084
    • Goriely, S.1    Molle, C.2    Nguyen, M.3    Albarani, V.4    Haddou, N.O.5    Lin, R.6
  • 66
    • 84866554596 scopus 로고    scopus 로고
    • ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells
    • Romagnoli A., Etna M.P., Giacomini E., Pardini M., Remoli M.E., Corazzari M., et al. ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells. Autophagy 2012, 8:1357-1370.
    • (2012) Autophagy , vol.8 , pp. 1357-1370
    • Romagnoli, A.1    Etna, M.P.2    Giacomini, E.3    Pardini, M.4    Remoli, M.E.5    Corazzari, M.6
  • 68
    • 84859972311 scopus 로고    scopus 로고
    • Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death
    • Simeone R., Bobard A., Lippmann J., Bitter W., Majlessi L., Brosch R., et al. Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death. PLoS Pathog 2012, 8:e1002507.
    • (2012) PLoS Pathog , vol.8 , pp. e1002507
    • Simeone, R.1    Bobard, A.2    Lippmann, J.3    Bitter, W.4    Majlessi, L.5    Brosch, R.6
  • 69
    • 23244458100 scopus 로고    scopus 로고
    • IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available
    • Khader S.A., Pearl J.E., Sakamoto K., Gilmartin L., Bell G.K., Jelley-Gibbs D.M., et al. IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available. J Immunol 2005, 175:788-795.
    • (2005) J Immunol , vol.175 , pp. 788-795
    • Khader, S.A.1    Pearl, J.E.2    Sakamoto, K.3    Gilmartin, L.4    Bell, G.K.5    Jelley-Gibbs, D.M.6
  • 70
    • 34548008127 scopus 로고    scopus 로고
    • Interleukin-12 and tuberculosis: an old story revisited
    • Cooper A.M., Solache A., Khader S.A. Interleukin-12 and tuberculosis: an old story revisited. Curr Opin Immunol 2007, 19:441-447.
    • (2007) Curr Opin Immunol , vol.19 , pp. 441-447
    • Cooper, A.M.1    Solache, A.2    Khader, S.A.3
  • 71
    • 10344261416 scopus 로고    scopus 로고
    • IL-27 signaling compromises control of bacterial growth in mycobacteria-infected mice
    • Pearl J.E., Khader S.A., Solache A., Gilmartin L., Ghilardi N., deSauvage F., et al. IL-27 signaling compromises control of bacterial growth in mycobacteria-infected mice. J Immunol 2004, 173:7490-7496.
    • (2004) J Immunol , vol.173 , pp. 7490-7496
    • Pearl, J.E.1    Khader, S.A.2    Solache, A.3    Gilmartin, L.4    Ghilardi, N.5    deSauvage, F.6
  • 72
    • 14844355133 scopus 로고    scopus 로고
    • The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis
    • Holscher C., Holscher A., Ruckerl D., Yoshimoto T., Yoshida H., Mak T., et al. The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis. J Immunol 2005, 174:3534-3544.
    • (2005) J Immunol , vol.174 , pp. 3534-3544
    • Holscher, C.1    Holscher, A.2    Ruckerl, D.3    Yoshimoto, T.4    Yoshida, H.5    Mak, T.6
  • 73
    • 33747593830 scopus 로고    scopus 로고
    • Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
    • Stumhofer J.S., Laurence A., Wilson E.H., Huang E., Tato C.M., Johnson L.M., et al. Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nat Immunol 2006, 7:937-945.
    • (2006) Nat Immunol , vol.7 , pp. 937-945
    • Stumhofer, J.S.1    Laurence, A.2    Wilson, E.H.3    Huang, E.4    Tato, C.M.5    Johnson, L.M.6
  • 75
    • 0036235268 scopus 로고    scopus 로고
    • Autocrine IL-10 impairs dendritic cell (DC)-derived immune responses to mycobacterial infection by suppressing DC trafficking to draining lymph nodes and local IL-12 production
    • Demangel C., Bertolino P., Britton W.J. Autocrine IL-10 impairs dendritic cell (DC)-derived immune responses to mycobacterial infection by suppressing DC trafficking to draining lymph nodes and local IL-12 production. Eur J Immunol 2002, 32:994-1002.
    • (2002) Eur J Immunol , vol.32 , pp. 994-1002
    • Demangel, C.1    Bertolino, P.2    Britton, W.J.3
  • 77
  • 78
  • 79
    • 80051566116 scopus 로고    scopus 로고
    • IL-10 blocks phagosome maturation in Mycobacterium tuberculosis-infected human macrophages
    • O'Leary S., O'Sullivan M.P., Keane J. IL-10 blocks phagosome maturation in Mycobacterium tuberculosis-infected human macrophages. Am J Respir Cell Mol Biol 2011, 45:172-180.
    • (2011) Am J Respir Cell Mol Biol , vol.45 , pp. 172-180
    • O'Leary, S.1    O'Sullivan, M.P.2    Keane, J.3
  • 80
    • 79952819124 scopus 로고    scopus 로고
    • Bystander inhibition of dendritic cell differentiation by Mycobacterium tuberculosis-induced IL-10
    • Remoli M.E., Giacomini E., Petruccioli E., Gafa V., Severa M., Gagliardi M.C., et al. Bystander inhibition of dendritic cell differentiation by Mycobacterium tuberculosis-induced IL-10. Immunol Cell Biol 2011, 89:437-446.
    • (2011) Immunol Cell Biol , vol.89 , pp. 437-446
    • Remoli, M.E.1    Giacomini, E.2    Petruccioli, E.3    Gafa, V.4    Severa, M.5    Gagliardi, M.C.6
  • 81
    • 49449098413 scopus 로고    scopus 로고
    • ESAT-6-specific CD4T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes
    • Reiley W.W., Calayag M.D., Wittmer S.T., Huntington J.L., Pearl J.E., Fountain J.J., et al. ESAT-6-specific CD4T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes. Proc Natl Acad Sci U S A 2008, 105:10961-10966.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 10961-10966
    • Reiley, W.W.1    Calayag, M.D.2    Wittmer, S.T.3    Huntington, J.L.4    Pearl, J.E.5    Fountain, J.J.6
  • 82
    • 84864925681 scopus 로고    scopus 로고
    • The tuberculous granuloma: an unsuccessful host defence mechanism providing a safety shelter for the bacteria?
    • Silva Miranda M., Breiman A., Allain S., Deknuydt F., Altare F. The tuberculous granuloma: an unsuccessful host defence mechanism providing a safety shelter for the bacteria?. Clin Dev Immunol 2012, 2012:139127.
    • (2012) Clin Dev Immunol , vol.2012 , pp. 139127
    • Silva Miranda, M.1    Breiman, A.2    Allain, S.3    Deknuydt, F.4    Altare, F.5
  • 83
    • 57149144518 scopus 로고    scopus 로고
    • The genetic heterogeneity of mendelian susceptibility to mycobacterial diseases
    • quiz 1052-1043
    • Al-Muhsen S., Casanova J.L. The genetic heterogeneity of mendelian susceptibility to mycobacterial diseases. J Allergy Clin Immunol 2008, 122:1043-1051. quiz 1052-1043.
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 1043-1051
    • Al-Muhsen, S.1    Casanova, J.L.2
  • 84
    • 0027360333 scopus 로고
    • An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection
    • Flynn J.L., Chan J., Triebold K.J., Dalton D.K., Stewart T.A., Bloom B.R. An essential role for interferon gamma in resistance to Mycobacterium tuberculosis infection. J Exp Med 1993, 178:2249-2254.
    • (1993) J Exp Med , vol.178 , pp. 2249-2254
    • Flynn, J.L.1    Chan, J.2    Triebold, K.J.3    Dalton, D.K.4    Stewart, T.A.5    Bloom, B.R.6
  • 85
    • 44649128524 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis and the macrophage: maintaining a balance
    • Pieters J. Mycobacterium tuberculosis and the macrophage: maintaining a balance. Cell Host Microbe 2008, 3:399-407.
    • (2008) Cell Host Microbe , vol.3 , pp. 399-407
    • Pieters, J.1
  • 86
    • 79953189362 scopus 로고    scopus 로고
    • Vaccine-induced anti-tuberculosis protective immunity in mice correlates with the magnitude and quality of multifunctional CD4T cells
    • Derrick S.C., Yabe I.M., Yang A., Morris S.L. Vaccine-induced anti-tuberculosis protective immunity in mice correlates with the magnitude and quality of multifunctional CD4T cells. Vaccine 2011, 29:2902-2909.
    • (2011) Vaccine , vol.29 , pp. 2902-2909
    • Derrick, S.C.1    Yabe, I.M.2    Yang, A.3    Morris, S.L.4
  • 87
    • 77956108181 scopus 로고    scopus 로고
    • Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection
    • Caccamo N., Guggino G., Joosten S.A., Gelsomino G., Di Carlo P., Titone L., et al. Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection. Eur J Immunol 2010, 40:2211-2220.
    • (2010) Eur J Immunol , vol.40 , pp. 2211-2220
    • Caccamo, N.1    Guggino, G.2    Joosten, S.A.3    Gelsomino, G.4    Di Carlo, P.5    Titone, L.6
  • 88
    • 84902603074 scopus 로고    scopus 로고
    • Directing traffic: IL-17 and IL-22 coordinate pulmonary immune defense
    • McAleer J.P., Kolls J.K. Directing traffic: IL-17 and IL-22 coordinate pulmonary immune defense. Immunol Rev 2014, 260:129-144.
    • (2014) Immunol Rev , vol.260 , pp. 129-144
    • McAleer, J.P.1    Kolls, J.K.2
  • 89
    • 84901659079 scopus 로고    scopus 로고
    • Unexpected role for IL-17 in protective immunity against hypervirulent Mycobacterium tuberculosis HN878 infection
    • Gopal R., Monin L., Slight S., Uche U., Blanchard E., Fallert Junecko B.A., et al. Unexpected role for IL-17 in protective immunity against hypervirulent Mycobacterium tuberculosis HN878 infection. PLoS Pathog 2014, 10:e1004099.
    • (2014) PLoS Pathog , vol.10 , pp. e1004099
    • Gopal, R.1    Monin, L.2    Slight, S.3    Uche, U.4    Blanchard, E.5    Fallert Junecko, B.A.6
  • 90
    • 79751529842 scopus 로고    scopus 로고
    • Cellular response to mycobacteria: balancing protection and pathology
    • Torrado E., Robinson R.T., Cooper A.M. Cellular response to mycobacteria: balancing protection and pathology. Trends Immunol 2011, 32:66-72.
    • (2011) Trends Immunol , vol.32 , pp. 66-72
    • Torrado, E.1    Robinson, R.T.2    Cooper, A.M.3
  • 91
    • 34248562792 scopus 로고    scopus 로고
    • IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge
    • Khader S.A., Bell G.K., Pearl J.E., Fountain J.J., Rangel-Moreno J., Cilley G.E., et al. IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge. Nat Immunol 2007, 8:369-377.
    • (2007) Nat Immunol , vol.8 , pp. 369-377
    • Khader, S.A.1    Bell, G.K.2    Pearl, J.E.3    Fountain, J.J.4    Rangel-Moreno, J.5    Cilley, G.E.6
  • 92
    • 33749983749 scopus 로고    scopus 로고
    • Interleukin-22: a novel T- and NK-cell derived cytokine that regulates the biology of tissue cells
    • Wolk K., Sabat R. Interleukin-22: a novel T- and NK-cell derived cytokine that regulates the biology of tissue cells. Cytokine Growth Factor Rev 2006, 17:367-380.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 367-380
    • Wolk, K.1    Sabat, R.2
  • 93
    • 79953048089 scopus 로고    scopus 로고
    • Regulation and functions of the IL-10 family of cytokines in inflammation and disease
    • Ouyang W., Rutz S., Crellin N.K., Valdez P.A., Hymowitz S.G. Regulation and functions of the IL-10 family of cytokines in inflammation and disease. Annu Rev Immunol 2011, 29:71-109.
    • (2011) Annu Rev Immunol , vol.29 , pp. 71-109
    • Ouyang, W.1    Rutz, S.2    Crellin, N.K.3    Valdez, P.A.4    Hymowitz, S.G.5
  • 94
    • 79952584368 scopus 로고    scopus 로고
    • Recent advances in IL-22 biology
    • Zenewicz L.A., Flavell R.A. Recent advances in IL-22 biology. Int Immunol 2011, 23:159-163.
    • (2011) Int Immunol , vol.23 , pp. 159-163
    • Zenewicz, L.A.1    Flavell, R.A.2
  • 95
    • 33749318470 scopus 로고    scopus 로고
    • Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
    • Liang S.C., Tan X.Y., Luxenberg D.P., Karim R., Dunussi-Joannopoulos K., Collins M., et al. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J Exp Med 2006, 203:2271-2279.
    • (2006) J Exp Med , vol.203 , pp. 2271-2279
    • Liang, S.C.1    Tan, X.Y.2    Luxenberg, D.P.3    Karim, R.4    Dunussi-Joannopoulos, K.5    Collins, M.6
  • 96
    • 84874533314 scopus 로고    scopus 로고
    • IL-22 is mainly produced by IFNgamma-secreting cells but is dispensable for host protection against Mycobacterium tuberculosis infection
    • Behrends J., Renauld J.C., Ehlers S., Holscher C. IL-22 is mainly produced by IFNgamma-secreting cells but is dispensable for host protection against Mycobacterium tuberculosis infection. PLoS ONE 2013, 8:e57379.
    • (2013) PLoS ONE , vol.8 , pp. e57379
    • Behrends, J.1    Renauld, J.C.2    Ehlers, S.3    Holscher, C.4
  • 97
    • 30444457915 scopus 로고    scopus 로고
    • Apoptotic vesicles crossprime CD8T cells and protect against tuberculosis
    • Winau F., Weber S., Sad S., de Diego J., Hoops S.L., Breiden B., et al. Apoptotic vesicles crossprime CD8T cells and protect against tuberculosis. Immunity 2006, 24:105-117.
    • (2006) Immunity , vol.24 , pp. 105-117
    • Winau, F.1    Weber, S.2    Sad, S.3    de Diego, J.4    Hoops, S.L.5    Breiden, B.6
  • 98
    • 84863690353 scopus 로고    scopus 로고
    • Vaccines against tuberculosis: where are we and where do we need to go?
    • Ottenhoff T.H., Kaufmann S.H. Vaccines against tuberculosis: where are we and where do we need to go?. PLoS Pathog 2012, 8:e1002607.
    • (2012) PLoS Pathog , vol.8 , pp. e1002607
    • Ottenhoff, T.H.1    Kaufmann, S.H.2
  • 99
    • 77955717510 scopus 로고    scopus 로고
    • Regulatory T cell frequency and modulation of IFN-gamma and IL-17 in active and latent tuberculosis
    • Marin N.D., Paris S.C., Velez V.M., Rojas C.A., Rojas M., Garcia L.F. Regulatory T cell frequency and modulation of IFN-gamma and IL-17 in active and latent tuberculosis. Tuberculosis (Edinb) 2010, 90:252-261.
    • (2010) Tuberculosis (Edinb) , vol.90 , pp. 252-261
    • Marin, N.D.1    Paris, S.C.2    Velez, V.M.3    Rojas, C.A.4    Rojas, M.5    Garcia, L.F.6
  • 100
    • 42249084604 scopus 로고    scopus 로고
    • Mannose-capped lipoarabinomannan- and prostaglandin E2-dependent expansion of regulatory T cells in human Mycobacterium tuberculosis infection
    • Garg A., Barnes P.F., Roy S., Quiroga M.F., Wu S., Garcia V.E., et al. Mannose-capped lipoarabinomannan- and prostaglandin E2-dependent expansion of regulatory T cells in human Mycobacterium tuberculosis infection. Eur J Immunol 2008, 38:459-469.
    • (2008) Eur J Immunol , vol.38 , pp. 459-469
    • Garg, A.1    Barnes, P.F.2    Roy, S.3    Quiroga, M.F.4    Wu, S.5    Garcia, V.E.6
  • 101
    • 77954390239 scopus 로고    scopus 로고
    • Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis
    • Shafiani S., Tucker-Heard G., Kariyone A., Takatsu K., Urdahl K.B. Pathogen-specific regulatory T cells delay the arrival of effector T cells in the lung during early tuberculosis. J Exp Med 2010, 207:1409-1420.
    • (2010) J Exp Med , vol.207 , pp. 1409-1420
    • Shafiani, S.1    Tucker-Heard, G.2    Kariyone, A.3    Takatsu, K.4    Urdahl, K.B.5
  • 102
    • 33847344205 scopus 로고    scopus 로고
    • Cutting edge: regulatory T cells prevent efficient clearance of Mycobacterium tuberculosis
    • Kursar M., Koch M., Mittrucker H.W., Nouailles G., Bonhagen K., Kamradt T., et al. Cutting edge: regulatory T cells prevent efficient clearance of Mycobacterium tuberculosis. J Immunol 2007, 178:2661-2665.
    • (2007) J Immunol , vol.178 , pp. 2661-2665
    • Kursar, M.1    Koch, M.2    Mittrucker, H.W.3    Nouailles, G.4    Bonhagen, K.5    Kamradt, T.6
  • 103
    • 57649090701 scopus 로고    scopus 로고
    • Human CD4 and CD8 regulatory T cells in infectious diseases and vaccination
    • Joosten S.A., Ottenhoff T.H. Human CD4 and CD8 regulatory T cells in infectious diseases and vaccination. Hum Immunol 2008, 69:760-770.
    • (2008) Hum Immunol , vol.69 , pp. 760-770
    • Joosten, S.A.1    Ottenhoff, T.H.2
  • 104
    • 72949119542 scopus 로고    scopus 로고
    • Translational mini-review series on Th17 cells: induction of interleukin-17 production by regulatory T cells
    • Afzali B., Mitchell P., Lechler R.I., John S., Lombardi G. Translational mini-review series on Th17 cells: induction of interleukin-17 production by regulatory T cells. Clin Exp Immunol 2010, 159:120-130.
    • (2010) Clin Exp Immunol , vol.159 , pp. 120-130
    • Afzali, B.1    Mitchell, P.2    Lechler, R.I.3    John, S.4    Lombardi, G.5
  • 105
    • 84882276233 scopus 로고    scopus 로고
    • Tuberculosis vaccines: time to think about the next generation
    • Kaufmann S.H. Tuberculosis vaccines: time to think about the next generation. Semin Immunol 2013, 25:172-181.
    • (2013) Semin Immunol , vol.25 , pp. 172-181
    • Kaufmann, S.H.1
  • 107
    • 70349967965 scopus 로고    scopus 로고
    • Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis
    • Taylor P.C., Feldmann M. Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis. Nat Rev Rheumatol 2009, 5:578-582.
    • (2009) Nat Rev Rheumatol , vol.5 , pp. 578-582
    • Taylor, P.C.1    Feldmann, M.2
  • 108
    • 0036219062 scopus 로고    scopus 로고
    • Genetic dissection of immunity to mycobacteria: the human model
    • Casanova J.L., Abel L. Genetic dissection of immunity to mycobacteria: the human model. Annu Rev Immunol 2002, 20:581-620.
    • (2002) Annu Rev Immunol , vol.20 , pp. 581-620
    • Casanova, J.L.1    Abel, L.2
  • 109
    • 84864744848 scopus 로고    scopus 로고
    • Is interferon-gamma the right marker for bacille Calmette-Guerin-induced immune protection? The missing link in our understanding of tuberculosis immunology
    • Abebe F. Is interferon-gamma the right marker for bacille Calmette-Guerin-induced immune protection? The missing link in our understanding of tuberculosis immunology. Clin Exp Immunol 2012, 169:213-219.
    • (2012) Clin Exp Immunol , vol.169 , pp. 213-219
    • Abebe, F.1


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