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Volumn 14, Issue 11, 2012, Pages 1734-1744

Natural killer cells are recruited during pulmonary tuberculosis and their ex vivo responses to mycobacteria vary between healthy human donors in association with KIR haplotype

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; CYTOKINE; DNA; GAMMA INTERFERON; INTERLEUKIN 2; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 84867629125     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2012.01834.x     Document Type: Article
Times cited : (52)

References (45)
  • 1
    • 44849083121 scopus 로고    scopus 로고
    • Natural killer cell subpopulations in putative resistant individuals and patients with active Mycobacterium tuberculosis infection
    • Barcelos, W., Sathler-Avelar, R., Martins-Filho, O.A., Carvalho, B.N., Guimaraes, T.M., Miranda, S.S., etal. (2008) Natural killer cell subpopulations in putative resistant individuals and patients with active Mycobacterium tuberculosis infection. Scand J Immunol 68: 92-102.
    • (2008) Scand J Immunol , vol.68 , pp. 92-102
    • Barcelos, W.1    Sathler-Avelar, R.2    Martins-Filho, O.A.3    Carvalho, B.N.4    Guimaraes, T.M.5    Miranda, S.S.6
  • 2
    • 70449705831 scopus 로고    scopus 로고
    • The spectrum of latent tuberculosis: rethinking the biology and intervention strategies
    • Barry, C.E., 3rd, Boshoff, H.I., Dartois, V., Dick, T., Ehrt, S., Flynn, J., etal. (2009) The spectrum of latent tuberculosis: rethinking the biology and intervention strategies. Nat Rev Microbiol 7: 845-855.
    • (2009) Nat Rev Microbiol , vol.7 , pp. 845-855
    • Barry 3rd, C.E.1    Boshoff, H.I.2    Dartois, V.3    Dick, T.4    Ehrt, S.5    Flynn, J.6
  • 3
    • 28944445570 scopus 로고    scopus 로고
    • Human CD56bright and CD56dim natural killer cell subsets respond differentially to direct stimulation with Mycobacterium bovis bacillus Calmette-Guerin
    • Batoni, G., Esin, S., Favilli, F., Pardini, M., Bottai, D., Maisetta, G., etal. (2005) Human CD56bright and CD56dim natural killer cell subsets respond differentially to direct stimulation with Mycobacterium bovis bacillus Calmette-Guerin. Scand J Immunol 62: 498-506.
    • (2005) Scand J Immunol , vol.62 , pp. 498-506
    • Batoni, G.1    Esin, S.2    Favilli, F.3    Pardini, M.4    Bottai, D.5    Maisetta, G.6
  • 5
    • 34250158132 scopus 로고    scopus 로고
    • Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class I in disease
    • Boyton, R.J., and Altmann, D.M. (2007) Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class I in disease. Clin Exp Immunol 149: 1-8.
    • (2007) Clin Exp Immunol , vol.149 , pp. 1-8
    • Boyton, R.J.1    Altmann, D.M.2
  • 6
    • 67649864078 scopus 로고    scopus 로고
    • Functionally relevant decreases in activatory receptor expression on NK cells are associated with pulmonary tuberculosis in vivo and persist after successful treatment
    • Bozzano, F., Costa, P., Passalacqua, G., Dodi, F., Ravera, S., Pagano, G., etal. (2009) Functionally relevant decreases in activatory receptor expression on NK cells are associated with pulmonary tuberculosis in vivo and persist after successful treatment. Int Immunol 21: 779-791.
    • (2009) Int Immunol , vol.21 , pp. 779-791
    • Bozzano, F.1    Costa, P.2    Passalacqua, G.3    Dodi, F.4    Ravera, S.5    Pagano, G.6
  • 7
    • 63149126181 scopus 로고    scopus 로고
    • NK cell education: not an on-off switch but a tunable rheostat
    • Brodin, P., Karre, K., and Hoglund, P. (2009) NK cell education: not an on-off switch but a tunable rheostat. Trends Immunol 30: 143-149.
    • (2009) Trends Immunol , vol.30 , pp. 143-149
    • Brodin, P.1    Karre, K.2    Hoglund, P.3
  • 8
    • 4444340990 scopus 로고    scopus 로고
    • Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha-defensin production
    • Chalifour, A., Jeannin, P., Gauchat, J.F., Blaecke, A., Malissard, M., N'Guyen, T., etal. (2004) Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers alpha-defensin production. Blood 104: 1778-1783.
    • (2004) Blood , vol.104 , pp. 1778-1783
    • Chalifour, A.1    Jeannin, P.2    Gauchat, J.F.3    Blaecke, A.4    Malissard, M.5    N'Guyen, T.6
  • 9
    • 61449212169 scopus 로고    scopus 로고
    • Natural killer cells: integrating diversity with function
    • Cheent, K., and Khakoo, S.I. (2009) Natural killer cells: integrating diversity with function. Immunology 126: 449-457.
    • (2009) Immunology , vol.126 , pp. 449-457
    • Cheent, K.1    Khakoo, S.I.2
  • 10
    • 73349135673 scopus 로고    scopus 로고
    • Two loci control tuberculin skin test reactivity in an area hyperendemic for tuberculosis
    • Cobat, A., Gallant, C.J., Simkin, L., Black, G.F., Stanley, K., Hughes, J., etal. (2009) Two loci control tuberculin skin test reactivity in an area hyperendemic for tuberculosis. J Exp Med 206: 2583-2591.
    • (2009) J Exp Med , vol.206 , pp. 2583-2591
    • Cobat, A.1    Gallant, C.J.2    Simkin, L.3    Black, G.F.4    Stanley, K.5    Hughes, J.6
  • 11
    • 0035499063 scopus 로고    scopus 로고
    • The biology of human natural killer-cell subsets
    • Cooper, M.A., Fehniger, T.A., and Caligiuri, M.A. (2001) The biology of human natural killer-cell subsets. Trends Immunol 22: 633-640.
    • (2001) Trends Immunol , vol.22 , pp. 633-640
    • Cooper, M.A.1    Fehniger, T.A.2    Caligiuri, M.A.3
  • 12
    • 79551666576 scopus 로고    scopus 로고
    • Revisiting human natural killer cell subset function revealed cytolytic CD56(dim)CD16+ NK cells as rapid producers of abundant IFN-gamma on activation
    • De Maria, A., Bozzano, F., Cantoni, C., and Moretta, L. (2011) Revisiting human natural killer cell subset function revealed cytolytic CD56(dim)CD16+ NK cells as rapid producers of abundant IFN-gamma on activation. Proc Natl Acad Sci USA 108: 728-732.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 728-732
    • De Maria, A.1    Bozzano, F.2    Cantoni, C.3    Moretta, L.4
  • 13
    • 42149091828 scopus 로고    scopus 로고
    • Direct binding of human NK cell natural cytotoxicity receptor NKp44 to the surfaces of mycobacteria and other bacteria
    • Esin, S., Batoni, G., Counoupas, C., Stringaro, A., Brancatisano, F.L., Colone, M., etal. (2008) Direct binding of human NK cell natural cytotoxicity receptor NKp44 to the surfaces of mycobacteria and other bacteria. Infect Immun 76: 1719-1727.
    • (2008) Infect Immun , vol.76 , pp. 1719-1727
    • Esin, S.1    Batoni, G.2    Counoupas, C.3    Stringaro, A.4    Brancatisano, F.L.5    Colone, M.6
  • 14
    • 33750816740 scopus 로고    scopus 로고
    • NK cell-derived IFN-gamma differentially regulates innate resistance and neutrophil response in T cell-deficient hosts infected with Mycobacterium tuberculosis
    • Feng, C.G., Kaviratne, M., Rothfuchs, A.G., Cheever, A., Hieny, S., Young, H.A., etal. (2006) NK cell-derived IFN-gamma differentially regulates innate resistance and neutrophil response in T cell-deficient hosts infected with Mycobacterium tuberculosis J Immunol 177: 7086-7093.
    • (2006) J Immunol , vol.177 , pp. 7086-7093
    • Feng, C.G.1    Kaviratne, M.2    Rothfuchs, A.G.3    Cheever, A.4    Hieny, S.5    Young, H.A.6
  • 16
    • 33750305145 scopus 로고    scopus 로고
    • Vimentin expressed on Mycobacterium tuberculosis-infected human monocytes is involved in binding to the NKp46 receptor
    • Garg, A., Barnes, P.F., Porgador, A., Roy, S., Wu, S., Nanda, J.S., etal. (2006) Vimentin expressed on Mycobacterium tuberculosis-infected human monocytes is involved in binding to the NKp46 receptor. J Immunol 177: 6192-6198.
    • (2006) J Immunol , vol.177 , pp. 6192-6198
    • Garg, A.1    Barnes, P.F.2    Porgador, A.3    Roy, S.4    Wu, S.5    Nanda, J.S.6
  • 17
    • 51849129336 scopus 로고    scopus 로고
    • Progression to active tuberculosis, but not transmission, varies by Mycobacterium tuberculosis lineage in The Gambia
    • de Jong, B.C., Hill, P.C., Aiken, A., Awine, T., Antonio, M., Adetifa, I.M., etal. (2008) Progression to active tuberculosis, but not transmission, varies by Mycobacterium tuberculosis lineage in The Gambia. J Infect Dis 198: 1037-1043.
    • (2008) J Infect Dis , vol.198 , pp. 1037-1043
    • de Jong, B.C.1    Hill, P.C.2    Aiken, A.3    Awine, T.4    Antonio, M.5    Adetifa, I.M.6
  • 18
    • 0345447607 scopus 로고    scopus 로고
    • NK cells respond to pulmonary infection with Mycobacterium tuberculosis, but play a minimal role in protection
    • Junqueira-Kipnis, A.P., Kipnis, A., Jamieson, A., Juarrero, M.G., Diefenbach, A., Raulet, D.H., etal. (2003) NK cells respond to pulmonary infection with Mycobacterium tuberculosis, but play a minimal role in protection. J Immunol 171: 6039-6045.
    • (2003) J Immunol , vol.171 , pp. 6039-6045
    • Junqueira-Kipnis, A.P.1    Kipnis, A.2    Jamieson, A.3    Juarrero, M.G.4    Diefenbach, A.5    Raulet, D.H.6
  • 19
    • 42949129193 scopus 로고    scopus 로고
    • HLA alleles determine differences in human natural killer cell responsiveness and potency
    • Kim, S., Sunwoo, J.B., Yang, L., Choi, T., Song, Y.J., French, A.R., etal. (2008) HLA alleles determine differences in human natural killer cell responsiveness and potency. Proc Natl Acad Sci USA 105: 3053-3058.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 3053-3058
    • Kim, S.1    Sunwoo, J.B.2    Yang, L.3    Choi, T.4    Song, Y.J.5    French, A.R.6
  • 20
    • 73949135879 scopus 로고    scopus 로고
    • Killer Ig-like receptor (KIR) genotype predicts the capacity of human KIR-positive CD56dim NK cells to respond to pathogen-associated signals
    • Korbel, D.S., Norman, P.J., Newman, K.C., Horowitz, A., Gendzekhadze, K., Parham, P., and Riley, E.M. (2009) Killer Ig-like receptor (KIR) genotype predicts the capacity of human KIR-positive CD56dim NK cells to respond to pathogen-associated signals. J Immunol 182: 6426-6434.
    • (2009) J Immunol , vol.182 , pp. 6426-6434
    • Korbel, D.S.1    Norman, P.J.2    Newman, K.C.3    Horowitz, A.4    Gendzekhadze, K.5    Parham, P.6    Riley, E.M.7
  • 21
    • 56549090945 scopus 로고    scopus 로고
    • The Yin and Yang of HLA and KIR in human disease
    • Kulkarni, S., Martin, M.P., and Carrington, M. (2008) The Yin and Yang of HLA and KIR in human disease. Semin Immunol 20: 343-352.
    • (2008) Semin Immunol , vol.20 , pp. 343-352
    • Kulkarni, S.1    Martin, M.P.2    Carrington, M.3
  • 22
    • 0022978436 scopus 로고
    • Natural killer cells: definition of a cell type rather than a function
    • Lanier, L.L., Phillips, J.H., Hackett, J., Jr, Tutt, M., and Kumar, V. (1986) Natural killer cells: definition of a cell type rather than a function. J Immunol 137: 2735-2739.
    • (1986) J Immunol , vol.137 , pp. 2735-2739
    • Lanier, L.L.1    Phillips, J.H.2    Hackett Jr., J.3    Tutt, M.4    Kumar, V.5
  • 24
    • 61949135568 scopus 로고    scopus 로고
    • Comparison of intracellular cytokine flow cytometry and an enzyme immunoassay for evaluation of cellular immune response to active tuberculosis
    • Leung, W.L., Law, K.L., Leung, V.S., Yip, C.W., Leung, C.C., Tam, C.M., and Kam, K.M. (2009) Comparison of intracellular cytokine flow cytometry and an enzyme immunoassay for evaluation of cellular immune response to active tuberculosis. Clin Vaccine Immunol 16: 344-351.
    • (2009) Clin Vaccine Immunol , vol.16 , pp. 344-351
    • Leung, W.L.1    Law, K.L.2    Leung, V.S.3    Yip, C.W.4    Leung, C.C.5    Tam, C.M.6    Kam, K.M.7
  • 26
    • 53749087426 scopus 로고    scopus 로고
    • Human NK cells directly recognize Mycobacterium bovis via TLR2 and acquire the ability to kill monocyte-derived DC
    • Marcenaro, E., Ferranti, B., Falco, M., Moretta, L., and Moretta, A. (2008) Human NK cells directly recognize Mycobacterium bovis via TLR2 and acquire the ability to kill monocyte-derived DC. Int Immunol 20: 1155-1167.
    • (2008) Int Immunol , vol.20 , pp. 1155-1167
    • Marcenaro, E.1    Ferranti, B.2    Falco, M.3    Moretta, L.4    Moretta, A.5
  • 27
    • 80053505409 scopus 로고    scopus 로고
    • Involvement of activating NK cell receptors and their modulation in pathogen immunity
    • Marras, F., Bozzano, F., and De Maria, A. (2011) Involvement of activating NK cell receptors and their modulation in pathogen immunity. J Biomed Biotechnol 2011: 152430.
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 152430
    • Marras, F.1    Bozzano, F.2    De Maria, A.3
  • 28
    • 45549108299 scopus 로고    scopus 로고
    • KIR locus polymorphisms: genotyping and disease association analysis
    • Martin, M.P., and Carrington, M. (2008) KIR locus polymorphisms: genotyping and disease association analysis. Methods Mol Biol 415: 49-64.
    • (2008) Methods Mol Biol , vol.415 , pp. 49-64
    • Martin, M.P.1    Carrington, M.2
  • 30
    • 77958143692 scopus 로고    scopus 로고
    • Humans differ from other hominids in lacking an activating NK cell receptor that recognizes the C1 epitope of MHC class I
    • Moesta, A.K., Graef, T., Abi-Rached, L., Older Aguilar, A.M., Guethlein, L.A., and Parham, P. (2010) Humans differ from other hominids in lacking an activating NK cell receptor that recognizes the C1 epitope of MHC class I. J Immunol 185: 4233-4237.
    • (2010) J Immunol , vol.185 , pp. 4233-4237
    • Moesta, A.K.1    Graef, T.2    Abi-Rached, L.3    Older Aguilar, A.M.4    Guethlein, L.A.5    Parham, P.6
  • 31
    • 0032212160 scopus 로고    scopus 로고
    • Fusion of azurophil granules with phagosomes and activation of the tyrosine kinase Hck are specifically inhibited during phagocytosis of mycobacteria by human neutrophils
    • N'Diaye, E.N., Darzacq, X., Astarie-Dequeker, C., Daffe, M., Calafat, J., and Maridonneau-Parini, I. (1998) Fusion of azurophil granules with phagosomes and activation of the tyrosine kinase Hck are specifically inhibited during phagocytosis of mycobacteria by human neutrophils. J Immunol 161: 4983-4991.
    • (1998) J Immunol , vol.161 , pp. 4983-4991
    • N'Diaye, E.N.1    Darzacq, X.2    Astarie-Dequeker, C.3    Daffe, M.4    Calafat, J.5    Maridonneau-Parini, I.6
  • 32
    • 14944355535 scopus 로고    scopus 로고
    • MHC class I molecules and KIRs in human history, health and survival
    • Parham, P. (2005) MHC class I molecules and KIRs in human history, health and survival. Nat Rev 5: 201-214.
    • (2005) Nat Rev , vol.5 , pp. 201-214
    • Parham, P.1
  • 33
    • 61449115971 scopus 로고    scopus 로고
    • CD56bright natural killer (NK) cells: an important NK cell subset
    • Poli, A., Michel, T., Theresine, M., Andres, E., Hentges, F., and Zimmer, J. (2009) CD56bright natural killer (NK) cells: an important NK cell subset. Immunology 126: 458-465.
    • (2009) Immunology , vol.126 , pp. 458-465
    • Poli, A.1    Michel, T.2    Theresine, M.3    Andres, E.4    Hentges, F.5    Zimmer, J.6
  • 34
    • 35648996461 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis-induced gamma interferon production by natural killer cells requires cross talk with antigen-presenting cells involving Toll-like receptors 2 and 4 and the mannose receptor in tuberculous pleurisy
    • Schierloh, P., Yokobori, N., Aleman, M., Landoni, V., Geffner, L., Musella, R.M., etal. (2007) Mycobacterium tuberculosis-induced gamma interferon production by natural killer cells requires cross talk with antigen-presenting cells involving Toll-like receptors 2 and 4 and the mannose receptor in tuberculous pleurisy. Infect Immun 75: 5325-5337.
    • (2007) Infect Immun , vol.75 , pp. 5325-5337
    • Schierloh, P.1    Yokobori, N.2    Aleman, M.3    Landoni, V.4    Geffner, L.5    Musella, R.M.6
  • 35
    • 35549003579 scopus 로고    scopus 로고
    • Regulation of interferon-gamma during innate and adaptive immune responses
    • Schoenborn, J.R., and Wilson, C.B. (2007) Regulation of interferon-gamma during innate and adaptive immune responses. Adv Immunol 96: 41-101.
    • (2007) Adv Immunol , vol.96 , pp. 41-101
    • Schoenborn, J.R.1    Wilson, C.B.2
  • 36
    • 84862602765 scopus 로고    scopus 로고
    • NK cell tolerance to TLR agonists mediated by regulatory T cells after polymicrobial sepsis
    • Souza-Fonseca-Guimaraes, F., Parlato, M., Fitting, C., Cavaillon, J.M., and Adib-Conquy, M. (2012) NK cell tolerance to TLR agonists mediated by regulatory T cells after polymicrobial sepsis. J Immunol 188: 5850-5858.
    • (2012) J Immunol , vol.188 , pp. 5850-5858
    • Souza-Fonseca-Guimaraes, F.1    Parlato, M.2    Fitting, C.3    Cavaillon, J.M.4    Adib-Conquy, M.5
  • 37
    • 59049094662 scopus 로고    scopus 로고
    • Adaptive immune features of natural killer cells
    • Sun, J.C., Beilke, J.N., and Lanier, L.L. (2009) Adaptive immune features of natural killer cells. Nature 457: 557-561.
    • (2009) Nature , vol.457 , pp. 557-561
    • Sun, J.C.1    Beilke, J.N.2    Lanier, L.L.3
  • 38
    • 84855475731 scopus 로고    scopus 로고
    • Susceptibility to pulmonary tuberculosis in Iranian individuals is not affected by compound KIR/HLA genotype
    • Tajik, N., Shah-Hosseini, A., Mohammadi, A., Jafari, M., Nasiri, M., Radjabzadeh, M.F., etal. (2012) Susceptibility to pulmonary tuberculosis in Iranian individuals is not affected by compound KIR/HLA genotype. Tissue Antigens 79: 90-96.
    • (2012) Tissue Antigens , vol.79 , pp. 90-96
    • Tajik, N.1    Shah-Hosseini, A.2    Mohammadi, A.3    Jafari, M.4    Nasiri, M.5    Radjabzadeh, M.F.6
  • 39
    • 10644226981 scopus 로고    scopus 로고
    • Shaping the human NK cell repertoire: an epigenetic glance at KIR gene regulation
    • Uhrberg, M. (2005) Shaping the human NK cell repertoire: an epigenetic glance at KIR gene regulation. Mol Immunol 42: 471-475.
    • (2005) Mol Immunol , vol.42 , pp. 471-475
    • Uhrberg, M.1
  • 40
    • 0036533578 scopus 로고    scopus 로고
    • The NKp46 receptor contributes to NK cell lysis of mononuclear phagocytes infected with an intracellular bacterium
    • Vankayalapati, R., Wizel, B., Weis, S.E., Safi, H., Lakey, D.L., Mandelboim, O., etal. (2002) The NKp46 receptor contributes to NK cell lysis of mononuclear phagocytes infected with an intracellular bacterium. J Immunol 168: 3451-3457.
    • (2002) J Immunol , vol.168 , pp. 3451-3457
    • Vankayalapati, R.1    Wizel, B.2    Weis, S.E.3    Safi, H.4    Lakey, D.L.5    Mandelboim, O.6
  • 41
    • 33847625418 scopus 로고    scopus 로고
    • Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46
    • Walzer, T., Blery, M., Chaix, J., Fuseri, N., Chasson, L., Robbins, S.H., etal. (2007) Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46. Proc Natl Acad Sci USA 104: 3384-3389.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 3384-3389
    • Walzer, T.1    Blery, M.2    Chaix, J.3    Fuseri, N.4    Chasson, L.5    Robbins, S.H.6
  • 42
    • 33645250323 scopus 로고    scopus 로고
    • The role of innate immune cells in the response of heat-treated Mycobacterium tuberculosis (M.tb) antigens stimulating PBMCs
    • Wang, C., Li, J., Zheng, H., Wei, H., Zhang, R., Li, B., and Tian, Z. (2004) The role of innate immune cells in the response of heat-treated Mycobacterium tuberculosis (M.tb) antigens stimulating PBMCs. Cell Mol Immunol 1: 467-470.
    • (2004) Cell Mol Immunol , vol.1 , pp. 467-470
    • Wang, C.1    Li, J.2    Zheng, H.3    Wei, H.4    Zhang, R.5    Li, B.6    Tian, Z.7
  • 43
    • 55849101475 scopus 로고    scopus 로고
    • Exposure of cord blood to Mycobacterium bovis BCG induces an innate response but not a T-cell cytokine response
    • Watkins, M.L., Semple, P.L., Abel, B., Hanekom, W.A., Kaplan, G., and Ress, S.R. (2008) Exposure of cord blood to Mycobacterium bovis BCG induces an innate response but not a T-cell cytokine response. Clin Vaccine Immunol 15: 1666-1673.
    • (2008) Clin Vaccine Immunol , vol.15 , pp. 1666-1673
    • Watkins, M.L.1    Semple, P.L.2    Abel, B.3    Hanekom, W.A.4    Kaplan, G.5    Ress, S.R.6
  • 44
    • 84875007047 scopus 로고    scopus 로고
    • WHO report (updated annually) Global tuberculosis control [WWW document]. Geneva.
    • WHO report (updated annually) Global tuberculosis control [WWW document]. URL: http://www.who.int/tb/publications/global_report/archive/en/index.html. Geneva.
  • 45
    • 34247538298 scopus 로고    scopus 로고
    • In vivo kinetics of human natural killer cells: the effects of ageing and acute and chronic viral infection
    • Zhang, Y., Wallace, D.L., de Lara, C.M., Ghattas, H., Asquith, B., Worth, A., etal. (2007) In vivo kinetics of human natural killer cells: the effects of ageing and acute and chronic viral infection. Immunology 121: 258-265.
    • (2007) Immunology , vol.121 , pp. 258-265
    • Zhang, Y.1    de Wallace, D.L.2    Lara, C.M.3    Ghattas, H.4    Asquith, B.5    Worth, A.6


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