Denbinobin upregulates miR-146a expression and attenuates IL-1β-induced upregulation of ICAM-1 and VCAM-1 expressions in osteoarthritis fibroblast-like synoviocytes

Journal of Molecular Medicine

Volumn 92, Issue 11, 2014, Pages 1147-1158

  Yang, Chia Ron ^a   Shih, Kao Shang ^b,c,d   Liou, Jing Ping ^e   Wu, Yi Wen ^a   Hsieh, I Ni ^a   Lee, Hsueh Yun ^e   Lin, Tzu Cheng ^e   Wang, Jyh Horng ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b SHIN KONG WU HO SU MEMORIAL HOSPITAL   (Taiwan)

^c FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Denbinobin; ICAM 1; miR 146a; VCAM 1

Indexed keywords

ANTIINFLAMMATORY AGENT; DENBINOBIN; HISTONE H3; HISTONE H4; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1BETA; MESSENGER RNA; MICRORNA 146A; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; ANTHRAQUINONE DERIVATIVE; ICAM1 PROTEIN, HUMAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA; MIRN146 MICRORNA, HUMAN; PHENANTHRENE DERIVATIVE;

AGED; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING SITE; CELL ADHESION; CLINICAL ARTICLE; CONTROLLED STUDY; FIBROBLAST LIKE SYNOVIOCYTE; HISTONE ACETYLATION; HUMAN; HUMAN CELL; MONOCYTE; OSTEOARTHRITIS; PROMOTER REGION; PROTEIN ACETYLATION; PROTEIN EXPRESSION; SYNOVIOCYTE; CHEMISTRY; CYTOLOGY; FIBROBLAST; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; HELA CELL LINE; INFLAMMATION; METABOLISM; PATELLA; PATHOLOGY; SIGNAL TRANSDUCTION; SYNOVIUM;

AGED; ANTHRAQUINONES; BINDING SITES; CELL ADHESION; EPIGENESIS, GENETIC; FIBROBLASTS; GENE EXPRESSION REGULATION; HELA CELLS; HUMANS; INFLAMMATION; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-1BETA; MICRORNAS; MICROSCOPY, FLUORESCENCE; MONOCYTES; NF-KAPPA B; OSTEOARTHRITIS; PATELLA; PHENANTHRENES; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE; SYNOVIOCYTES; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84919837963     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-014-1192-8     Document Type: Article

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