Targeting sites of inflammation: Intercellular adhesion molecule-1 as a target for novel inflammatory therapies

Frontiers in Pharmacology

Volumn 4 OCT, Issue , 2013, Pages

  Hua, Susan ^a  

^a UNIVERSITY OF NEWCASTLE   (Australia)

Author keywords

Cell adhesion molecules; ICAM 1; Inflammation; Liposomes; Targeted drug delivery

Indexed keywords

5' FLUORODEOXYURIDINE DIPALMITATE; ANTIINFLAMMATORY AGENT; DRUG CARRIER; IMMUNOLIPOSOME; INDOMETACIN; INTERCELLULAR ADHESION MOLECULE 1; LIPOSOME; LOPERAMIDE; MACROGOL; MICROSPHERE; NANOPARTICLE; OPIATE; POLYGLACTIN; PREDNISOLONE SODIUM PHOSPHATE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTHRITIS; BIOACCUMULATION; CHRONIC INFLAMMATION; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; DRUG MECHANISM; DRUG SAFETY; DRUG TARGETING; DRUG TISSUE LEVEL; DRUG TOLERABILITY; ENCAPSULATION; HUMAN; IMMUNOREGULATION; INFLAMMATION; INFLAMMATORY CELL; INFLAMMATORY DISEASE; LEUKOCYTE MIGRATION; LIPID VESICLE; MAXIMUM PLASMA CONCENTRATION; NOCICEPTION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SHORT SURVEY; TARGET CELL;

EID: 84885333451     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2013.00127     Document Type: Short Survey

References (49)

1. Almenar-Queralt, A., Duperray, A., Miles, L. A., Felez, J., and Altieri, D. C. (1995). Apical topography and modulation of ICAM-1 expression on activated endothelium. Am. J. Pathol. 147, 1278-1288.
2. Antohe, F., Lin, L., Kao, G. Y., Poznansky, M. J., and Allen, T. M. (2004). Transendothelial movement of liposomes in vitro mediated by cancer cells, neutrophils or histamine. J. Liposome Res. 14, 1-25. doi:10.1081/LPR-120039660.
3. Asgeirsdottir, S. A., Kok, R. J., Everts, M., Meijer, D. K., and Molema, G. (2003). Delivery of pharmacologically active dexamethasone into activated endothelial cells by dexamethasone-anti-E-selectin immunoconjugate. Biochem. Pharmacol. 65, 1729-1739. doi:10.1016/S0006-2952(03)00122-9.
4. Bendas, G. (2001). Immunoliposomes:a promising approach to targeting cancer therapy. BioDrugs 15, 215-224. doi:10.2165/00063030-200115040-00002.
5. Bendas, G., Krause, A., Schmidt, R., Vogel, J., and Rothe, U. (1998). Selectins as new targets for immunoliposome-mediated drug delivery. A potential way of anti-inflammatory therapy. Pharm. Acta Helv. 73, 19-26. doi:10.1016/S0031-6865(97)00043-5.
6. Bloemen, P. G., Henricks, P. A., van Bloois, L., van den Tweel, M. C., Bloem, A. C., Nijkamp, F. P., et al. (1995). Adhesion molecules:a new target for immunoliposome-mediated drug delivery. FEBS Lett. 357, 140-144. doi:10.1016/0014-5793(94)01350-A.
7. Boot, E. P., Koning, G. A., Storm, G., Wagenaar-Hilbers, J. P., van Eden, W., Everse, L. A., et al. (2005). CD134 as target for specific drug delivery to auto-aggressive CD4+ T cells in adjuvant arthritis. Arthritis Res. Ther. 7, R604-R615. doi:10.1186/ar1722.
8. Chittasupho, C., Xie, S., Baoum, A., Yakovleva, T., Siahaan, T. J., and Berkland, C. J. (2009). ICAM-1 targeting of doxorubicin-loaded PLGA nanoparticles to lung epithelial cells. Eur. J. Pharm. Sci. 2009, 141-150. doi:10.1016/j.ejps.2009.02.008.
9. Ding, B. S., Dziubla, T., Shuvaev, V. V., Muro, S., and Muzykantov, V. R. (2006). Advanced drug delivery systems that target the vascular endothelium. Mol. Interv. 6, 98-112. doi:10.1124/mi.6.2.7.
10. Everts, M., Koning, G. A., Kok, R. J., Asgeirsdottir, S. A., Vestweber, D., Meijer, D. K., et al. (2003). In vitro cellular handling and in vivo targeting of E-selectin-directed immunoconjugates and immunoliposomes used for drug delivery to inflamed endothelium. Pharm. Res. 20, 64-72. doi:10.1023/A:1022298725165.
11. Hua, S., and Cabot, P. J. (2013). Targeted nanoparticles that mimic immune cells in pain control inducing analgesic and anti-inflammatory actions:a potential novel treatment of acute and chronic pain condition. Pain Physician 16, E199-E216.
12. Hua, S., Hermanussen, S., Tang, L., Monteith, G. R., and Cabot, P. J. (2006). The neural cell adhesion molecule antibody blocks cold water swim stress-induced analgesia and cell adhesion between lymphocytes and cultured dorsal root ganglion neurons. Anesth. Analg. 103, 1558-1564. doi:10.1213/01.ane.0000243410.61451.c1.
13. Hubbard, A. K., and Rothlein, R. (2000). Intercellular adhesion molecule-1 (ICAM-1) expression and cell signaling cascades. Free Radic. Biol. Med. 28, 1379-1386. doi:10.1016/S0891-5849(00)00223-9.
14. Jaafari, M. R., and Foldvari, M. (2002a). Targeting of liposomes to human keratinocytes through adhesive peptides from immunoglobulin domains in the presence of IFN-gamma. Drug Deliv. 9, 1-9. doi:10.1080/107175402753413127.
15. Jaafari, M. R., and Foldvari, M. (2002b). Targeting of liposomes to melanoma cells with high levels of ICAM-1 expression through adhesive peptides from immunoglobulin domains. J. Pharm. Sci. 91, 396-404. doi:10.1002/jps.10062.
16. Janssen, A. P., Schiffelers, R. M., ten Hagen, T. L., Koning, G. A., Schraa, A. J., Kok, R. J., et al. (2003). Peptide-targeted PEG-liposomes in anti-angiogenic therapy. Int. J. Pharm. 254, 55-58. doi:10.1016/S0378-5173(02)00682-8.
17. Kessner, S., Krause, A., Rothe, U., and Bendas, G. (2001). Investigation of the cellular uptake of E-Selectin-targeted immunoliposomes by activated human endothelial cells. Biochim. Biophys. Acta 1514, 177-190. doi:10.1016/S0005-2736(01)00368-6.
18. Klimuk, S. K., Semple, S. C., Scherrer, P., and Hope, M. J. (1999). Contact hypersensitivity:a simple model for the characterization of disease-site targeting by liposomes. Biochim. Biophys. Acta 1417, 191-201. doi:10.1016/S0005-2736(98)00261-2.
19. Koning, G. A., Schiffelers, R. M., and Storm, G. (2002). Endothelial cells at inflammatory sites as target for therapeutic intervention. Endothelium 9, 161-171. doi:10.1080/10623320213631.
20. Laverman, P., Boerman, O. C., Oyen, W. J., Dams, E. T., Storm, G., and Corstens, F. H. (1999). Liposomes for scintigraphic detection of infection and inflammation. Adv. Drug Deliv. Rev. 37, 225-235. doi:10.1016/S0169-409X(98)00095-7.
21. Maruyama, K. (2002). PEG-immunoliposome. Biosci. Rep. 22, 251-266. doi:10.1023/A:1020138622686.
22. Mastrobattista, E., Storm, G., van Bloois, L., Reszka, R., Bloemen, P. G., Crommelin, D. J., et al. (1999). Cellular uptake of liposomes targeted to intercellular adhesion molecule-1 (ICAM-1) on bronchial epithelial cells. Biochim. Biophys. Acta 1419, 353-363. doi:10.1016/S0005-2736(99)00074-7.
23. Metselaar, J. M., and Storm, G. (2005). Liposomes in the treatment of inflammatory disorders. Expert Opin. Drug Deliv. 2, 465-476. doi:10.1517/17425247.2.3.465.
24. Metselaar, J. M., Wauben, M. H., Wagenaar-Hilbers, J. P., Boerman, O. C., and Storm, G. (2003). Complete remission of experimental arthritis by joint targeting of glucocorticoids with long-circulating liposomes. Arthritis Rheum. 48, 2059-2066. doi:10.1002/art.11140.
25. Mojcik, C. F., and Shevach, E. M. (1997). Adhesion molecules:a rheumatologic perspective. Arthritis Rheum. 40, 991-1004. doi:10.1002/art.1780400602.
26. Murciano, J. C., Muro, S., Koniaris, L., Christofidou-Solomidou, M., Harshaw, D. W., Albelda, S. M., et al. (2003). ICAM-directed vascular immunotargeting of antithrombotic agents to the endothelial luminal surface. Blood 101, 3977-3984. doi:10.1182/blood-2002-09-2853.
27. Muro, S., Cui, X., Gajewski, C., Murciano, J. C., Muzykantov, V. R., and Koval, M. (2003a). Slow intracellular trafficking of catalase nanoparticles targeted to ICAM-1 protects endothelial cells from oxidative stress. Am. J. Physiol. Cell Physiol. 285, C1339-C1347. doi:10.1152/ajpcell.00099.2003.
28. Muro, S., Wiewrodt, R., Thomas, A., Koniaris, L., Albelda, S. M., Muzykantov, V. R., et al. (2003b). A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1. J. Cell Sci. 116(Pt 8), 1599-1609. doi:10.1242/jcs.00367.
29. Muro, S., Gajewski, C., Koval, M., and Muzykantov, V. R. (2005). ICAM-1 recycling in endothelial cells:a novel pathway for sustained intracellular delivery and prolonged effects of drugs. Blood 105, 650-658. doi:10.1182/blood-2004-05-1714.
30. Muro, S., and Muzykantov, V. R. (2005). Targeting of antioxidant and anti-thrombotic drugs to endothelial cell adhesion molecules. Curr. Pharm. Des. 11, 2383-2401. doi:10.2174/1381612054367274.
31. Oku, N., and Namba, Y. (1994). Long-circulating liposomes. Crit. Rev. Ther. Drug Carrier Syst. 11, 231-270.
32. Palakurthi, S., Vyas, S. P., and Diwan, P. V. (2005). Biodisposition of PEG-coated lipid microspheres of indomethacin in arthritic rats. Int. J. Pharm. 290, 55-62. doi:10.1016/j.ijpharm.2004.11.017.
33. Przewlocki, R., and Przewlocka, B. (2001). Opioids in chronic pain. Eur. J. Pharmacol. 429, 79-91. doi:10.1016/S0014-2999(01)01308-5.
34. Rousseau, V., Denizot, B., Le Jeune, J. J., and Jallet, P. (1999). Early detection of liposome brain localization in rat experimental allergic encephalomyelitis. Exp. Brain Res. 125, 255-264. doi:10.1007/s002210050681.
35. Sakhalkar, H. S., Dalal, M. K., Salem, A. K., Ansari, R., Fu, J., Kiani, M. F., et al. (2003). Leukocyte-inspired biodegradable particles that selectively and avidly adhere to inflamed endothelium in vitro and in vivo. Proc. Natl. Acad. Sci. U.S.A. 100, 15895-15900. doi:10.1073/pnas.2631433100.
36. Schmidt, J., Metselaar, J. M., Wauben, M. H., Toyka, K. V., Storm, G., and Gold, R. (2003). Drug targeting by long-circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis. Brain 126(Pt 8), 1895-1904. doi:10.1093/brain/awg176.
37. Scholz, D., Devaux, B., Hirche, A., Potzsch, B., Kropp, B., Schaper, W., et al. (1996). Expression of adhesion molecules is specific and time-dependent in cytokine-stimulated endothelial cells in culture. Cell Tissue Res. 284, 415-423. doi:10.1007/s004410050602.
38. Senior, J. H. (1987). Fate and behavior of liposomes in vivo:a review of controlling factors. Crit. Rev. Ther. Drug Carrier Syst. 3, 123-193.
39. Sipkins, D. A., Gijbels, K., Tropper, F. D., Bednarski, M., Li, K. C., and Steinman, L. (2000). ICAM-1 expression in autoimmune encephalitis visualized using magnetic resonance imaging. J. Neuroimmunol. 104, 1-9. doi:10.1016/S0165-5728(99)00248-9.
40. Spragg, D. D., Alford, D. R., Greferath, R., Larsen, C. E., Lee, K. D., Gurtner, G. C., et al. (1997). Immunotargeting of liposomes to activated vascular endothelial cells:a strategy for site-selective delivery in the cardiovascular system. Proc. Natl. Acad. Sci. U.S.A. 94, 8795-8800. doi:10.1073/pnas.94.16.8795.
41. Stein, C., Machelska, H., and Schafer, M. (2001). Peripheral analgesic and antiinflammatory effects of opioids. Z. Rheumatol. 60, 416-424. doi:10.1007/s003930170004.
42. Thurston, G., McLean, J. W., Rizen, M., Baluk, P., Haskell, A., Murphy, T. J., et al. (1998). Cationic liposomes target angiogenic endothelial cells in tumors and chronic inflammation in mice. J. Clin. Invest. 101, 1401-1413. doi:10.1172/JCI965.
43. Torchilin, V. P. (1994). Immunoliposomes and PEGylated immunoliposomes:possible use for targeted delivery of imaging agents. Immunomethods 4, 244-258. doi:10.1006/immu.1994.1027.
44. Torchilin, V. P. (1996). Affinity liposomes in vivo:factors influencing target accumulation. J. Mol. Recognit. 9, 335-346. doi:10.1002/(SICI)1099-1352(199634/12)9:5/6<335::AID-JMR309>3.0.CO;2-0.
45. Ulrich, A. S. (2002). Biophysical aspects of using liposomes as delivery vehicles. Biosci. Rep. 22, 129-150. doi:10.1023/A:1020178304031.
46. Vingerhoeds, M. H., Storm, G., and Crommelin, D. J. (1994). Immunoliposomes in vivo. Immunomethods 4, 259-272. doi:10.1006/immu.1994.1028.
47. Voinea, M., Manduteanu, I., Dragomir, E., Capraru, M., and Simionescu, M. (2005). Immunoliposomes directed toward VCAM-1 interact specifically with activated endothelial cells-a potential tool for specific drug delivery. Pharm. Res. 22, 1906-1917. doi:10.1007/s11095-005-7247-3.
48. Willis, M., and Forssen, E. (1998). Ligand-targeted liposomes. Adv. Drug Deliv. Rev. 29, 249-271. doi:10.1016/S0169-409X(97)00083-5.
49. Yuan, F., Leunig, M., Huang, S. K., Berk, D. A., Papahadjopoulos, D., and Jain, R. K. (1994). Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft. Cancer Res. 54, 3352-3356.