Cooperation of p300 and PCAF in the control of microRNA 200c/141 transcription and epithelial characteristics

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Mizuguchi, Yoshiaki ^a   Specht, Susan ^a   Lunz, John G ^a   Isse, Kumiko ^a   Corbitt, Natasha ^a   Takizawa, Toshihiro ^b   Demetris, Anthony J ^a  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALVASCULIN; HISTIDINE; HISTONE ACETYLTRANSFERASE PCAF; LYSINE; MICRORNA; MICRORNA 141; MICRORNA 200B; MICRORNA 200C; MICRORNA 429; PROTEIN; PROTEIN P300; SMALL PROLINE RICH PROTEIN 2A; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ZEB1; TRICHOSTATIN A; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; CORNIFIED ENVELOPE LIKE PROLINE RICH PROTEIN; MIRN141 MICRORNA, HUMAN; MIRN141 MICRORNA, MOUSE; MIRN200 MICRORNA, HUMAN; MIRN200 MICRORNA, MOUSE; P300-CBP-ASSOCIATED FACTOR; SPRR2A PROTEIN, HUMAN; SPRR2A PROTEIN, MOUSE;

ACETYLATION; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DEMETHYLATION; EPITHELIAL MESENCHYMAL TRANSITION; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RNA TRANSCRIPTION; SNAIL GENE; SPRR2A GENE; STABLE TRANSFECTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TRANSCRIPTION SUPPRESSION; TWIST GENE; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; EPITHELIUM; GENETIC TRANSCRIPTION; METABOLISM; PHENOTYPE; PROTEIN SYNTHESIS; TUMOR CELL LINE; UPREGULATION;

ANIMALS; CELL LINE, TUMOR; CORNIFIED ENVELOPE PROLINE-RICH PROTEINS; EPITHELIAL-MESENCHYMAL TRANSITION; EPITHELIUM; HUMANS; MICE; MICRORNAS; MODELS, GENETIC; P300-CBP TRANSCRIPTION FACTORS; PHENOTYPE; PROMOTER REGIONS, GENETIC; PROTEIN BIOSYNTHESIS; TRANSCRIPTION, GENETIC; UP-REGULATION;

EID: 84857495668     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032449     Document Type: Article

References (32)

1. Bedford DC, Kasper LH, Fukuyama T, Brindle PK, (2010) Target gene context influences the transcriptional requirement for the KAT3 family of CBP and p300 histone acetyltransferases. Epigenetics 5: 9-15.
2. Chan HM, La Thangue NB, (2001) p300/CBP proteins: HATs for transcriptional bridges and scaffolds. J Cell Sci 114: 2363-2373.
3. Iyer NG, Ozdag H, Caldas C, (2004) p300/CBP and cancer. Oncogene 23: 4225-4231.
4. Gayther SA, Batley SJ, Linger L, Bannister A, Thorpe K, et al. (2000) Mutations truncating the EP300 acetylase in human cancers. Nat Genet 24: 300-303.
5. Adcock IM, Tsaprouni L, Bhavsar P, Ito K, (2007) Epigenetic regulation of airway inflammation. Curr Opin Immunol 19: 694-700.
6. Cereseto A, Manganaro L, Gutierrez MI, Terreni M, Fittipaldi A, et al. (2005) Acetylation of HIV-1 integrase by p300 regulates viral integration. EMBO J 24: 3070-3081.
7. Krubasik D, Iyer NG, English WR, Ahmed AA, Vias M, et al. (2006) Absence of p300 induces cellular phenotypic changes characteristic of epithelial to mesenchyme transition. Br J Cancer 94: 1326-1332.
8. Bai L, Merchant JL, (2007) A role for CITED2, a CBP/p300 interacting protein, in colon cancer cell invasion. FEBS Lett 581: 5904-5910.
9. Thiery JP, Acloque H, Huang RY, Nieto MA, (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890.
10. Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, et al. (2008) The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 10: 593-601.
11. Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, et al. (2008) A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res 68: 7846-7854.
12. Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, et al. (2008) A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 9: 582-589.
13. Nakada C, Matsuura K, Tsukamoto Y, Tanigawa M, Yoshimoto T, et al. (2008) Genome-wide microRNA expression profiling in renal cell carcinoma: significant down-regulation of miR-141 and miR-200c. J Pathol 216: 418-427.
14. Tryndyak VP, Ross SA, Beland FA, Pogribny IP, (2009) Down-regulation of the microRNAs miR-34a, miR-127, and miR-200b in rat liver during hepatocarcinogenesis induced by a methyl-deficient diet. Mol Carcinog 48: 479-487.
15. Yang J, Weinberg RA, (2008) Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Dev Cell 14: 818-829.
16. Demetris AJ, Specht S, Nozaki I, Lunz JG 3rd, Stolz DB, et al. (2008) Small proline-rich proteins (SPRR) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes. J Hepatol 48: 276-288.
17. Han C, Demetris AJ, Liu Y, Shelhamer JH, Wu T, (2004) Transforming growth factor-beta (TGF-beta) activates cytosolic phospholipase A2alpha (cPLA2alpha)-mediated prostaglandin E2 (PGE)2/EP1 and peroxisome proliferator-activated receptor-gamma (PPAR-gamma)/Smad signaling pathways in human liver cancer cells. A novel mechanism for subversion of TGF-beta-induced mitoinhibition. J Biol Chem 279: 44344-44354.
18. Cameron EE, Bachman KE, Myohanen S, Herman JG, Baylin SB, (1999) Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer. Nat Genet 21: 103-107.
19. Hata A, Seoane J, Lagna G, Montalvo E, Hemmati-Brivanlou A, et al. (2000) OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways. Cell 100: 229-240.
20. Neves R, Scheel C, Weinhold S, Honisch E, Iwaniuk KM, et al. Role of DNA methylation in miR-200c/141 cluster silencing in invasive breast cancer cells. BMC Res Notes 3: 219.
21. Thiery JP, Sleeman JP, (2006) Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol 7: 131-142.
22. Postigo AA, Dean DC, (1997) ZEB, a vertebrate homolog of Drosophila Zfh-1, is a negative regulator of muscle differentiation. EMBO J 16: 3935-3943.
23. Postigo AA, Dean DC, (1999) ZEB represses transcription through interaction with the corepressor CtBP. Proc Natl Acad Sci U S A 96: 6683-6688.
24. Postigo AA, Depp JL, Taylor JJ, Kroll KL, (2003) Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins. EMBO J 22: 2453-2462.
25. Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, et al. (1993) Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365: 855-859.
26. Eckner R, Ewen ME, Newsome D, Gerdes M, DeCaprio JA, et al. (1994) Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev 8: 869-884.
27. Karamouzis MV, Konstantinopoulos PA, Papavassiliou AG, (2007) Roles of CREB-binding protein (CBP)/p300 in respiratory epithelium tumorigenesis. Cell Res 17: 324-332.
28. Eckner R, Ludlow JW, Lill NL, Oldread E, Arany Z, et al. (1996) Association of p300 and CBP with simian virus 40 large T antigen. Mol Cell Biol 16: 3454-3464.
29. Yang XJ, Ogryzko VV, Nishikawa J, Howard BH, Nakatani Y, (1996) A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A. Nature 382: 319-324.
30. Pena C, Garcia JM, Garcia V, Silva J, Dominguez G, et al. (2006) The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas. Int J Cancer 119: 2098-2104.
31. Liu YN, Lee WW, Wang CY, Chao TH, Chen Y, et al. (2005) Regulatory mechanisms controlling human E-cadherin gene expression. Oncogene 24: 8277-8290.
32. Xu J, Lamouille S, Derynck R, (2009) TGF-beta-induced epithelial to mesenchymal transition. Cell Res 19: 156-172.