-
1
-
-
21044451297
-
CD14 and toll-like receptors: Potential contribution of genetic factors and mechanisms to inflammation and allergy
-
Leung TF, Tang NL, Tang NL, Wong GW, Fok TF: CD14 and toll-like receptors: potential contribution of genetic factors and mechanisms to inflammation and allergy. Curr Drug Targets Inflamm Allergy 4:169-175, 2005.
-
(2005)
Curr Drug Targets Inflamm Allergy
, vol.4
, pp. 169-175
-
-
Leung, T.F.1
Tang, N.L.2
Tang, N.L.3
Wong, G.W.4
Fok, T.F.5
-
2
-
-
0035451363
-
Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phyto-chemicals: Down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation
-
Surh YJ, Chun KS, Cha HH, Han SS, Keum YS, Park KK, Lee SS: Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phyto-chemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation. Mutat Res 480-481:243-268, 2001.
-
(2001)
Mutat Res 480-481
, pp. 243-268
-
-
Surh, Y.J.1
Chun, K.S.2
Cha, H.H.3
Han, S.S.4
Keum, Y.S.5
Park, K.K.6
Lee, S.S.7
-
3
-
-
0033067431
-
Effects of nitric oxide and nitric oxideY derived species on prostaglandin endoperoxide synthase and prostaglandin biosynthesis
-
Goodwin DC, Landino LM, Marnett LJ: Effects of nitric oxide and nitric oxideY derived species on prostaglandin endoperoxide synthase and prostaglandin biosynthesis. FASEB J 13:1121-1136, 1999.
-
(1999)
FASEB J
, vol.13
, pp. 1121-1136
-
-
Goodwin, D.C.1
Landino, L.M.2
Marnett, L.J.3
-
4
-
-
29344465714
-
Inducible nitric oxide synthase binds S-nitrosylates and activates cyclooxygenase-2
-
Kim SF, Huri DA, Snyder SH: Inducible nitric oxide synthase binds, S-nitrosylates, and activates cyclooxygenase-2. Science 310:1966-1970, 2005.
-
(2005)
Science
, vol.310
, pp. 1966-1970
-
-
Kim, S.F.1
Huri, D.A.2
Snyder, S.H.3
-
5
-
-
0344436050
-
Induction of nitric oxide synthase and dual effects of nitric oxide and cyclooxygenase products in regulation of arterial contraction in human septic shock
-
Stoclet JC, Mart́nez MC, Ohlmann P, Chasserot S, Schott C, Kleschyov AL, Schneider F, Andriantsitohaina R: Induction of nitric oxide synthase and dual effects of nitric oxide and cyclooxygenase products in regulation of arterial contraction in human septic shock. Circulation 100:107-112, 1999.
-
(1999)
Circulation
, vol.100
, pp. 107-112
-
-
Stoclet, J.C.1
Mart́nez, M.C.2
Ohlmann, P.3
Chasserot, S.4
Schott, C.5
Kleschyov, A.L.6
Schneider, F.7
Andriantsitohaina, R.8
-
6
-
-
71849086592
-
NO role of NOS2A susceptibility polymorphisms in rheumatoid arthritis
-
Varade J, Lamas JR, Fernández-Arquero M, Jover JA, de la Concha EG, Mart́nez A, Fernández-Gutierrez B, Urcelay E: NO role of NOS2A susceptibility polymorphisms in rheumatoid arthritis. Nitric Oxide 21:171-174, 2009.
-
(2009)
Nitric Oxide
, vol.21
, pp. 171-174
-
-
Varade, J.1
Lamas, J.R.2
Fernández-Arquero, M.3
Jover, J.A.4
De La Concha, E.G.5
Mart́nez, A.6
Fernández-Gutierrez, B.7
Urcelay, E.8
-
7
-
-
0028213334
-
Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids
-
Crofford LJ, Wilder RL, Ristimäki AP, Sano H, Remmers EF, Epps HR, Hla T: Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues. Effects of interleukin-1 beta, phorbol ester, and corticosteroids. J Clin Invest 93:1095-1101, 1994.
-
(1994)
J Clin Invest
, vol.93
, pp. 1095-1101
-
-
Crofford, L.J.1
Wilder, R.L.2
Ristimäki, A.P.3
Sano, H.4
Remmers, E.F.5
Epps, H.R.6
Hla, T.7
-
8
-
-
40449106779
-
Cyclooxygenase-2/prostaglandin D2/CRTH2 pathway mediates double-stranded RNA-induced enhancement of allergic airway inflammation
-
Shiraishi Y, Asano K, Niimi K, Fukunaga K, Wakaki M, Kagyo J, Takihara T, Ueda S, Nakajima T, Oguma T, et al.: Cyclooxygenase-2/prostaglandin D2/CRTH2 pathway mediates double-stranded RNA-induced enhancement of allergic airway inflammation. J Immunol 180:541-549, 2008.
-
(2008)
J Immunol
, vol.180
, pp. 541-549
-
-
Shiraishi, Y.1
Asano, K.2
Niimi, K.3
Fukunaga, K.4
Wakaki, M.5
Kagyo, J.6
Takihara, T.7
Ueda, S.8
Nakajima, T.9
Oguma, T.10
-
9
-
-
0031800817
-
Role of inducible nitric oxide syn-thase and cyclooxygenase-2 in endotoxin-induced cerebral hyperemia
-
Okamoto H, Ito O, Roman RJ, Hudetz AG: Role of inducible nitric oxide syn-thase and cyclooxygenase-2 in endotoxin-induced cerebral hyperemia. Stroke 29:1209-1218, 1998.
-
(1998)
Stroke
, vol.29
, pp. 1209-1218
-
-
Okamoto, H.1
Ito, O.2
Roman, R.J.3
Hudetz, A.G.4
-
10
-
-
0029888082
-
Molecular cloning and expression of an avian macrophage nitric-oxide synthase cDNA and the analysis of the genomic 5¶-flanking region
-
Lin AW, Chang CC, McCormick CC: Molecular cloning and expression of an avian macrophage nitric-oxide synthase cDNA and the analysis of the genomic 5¶-flanking region. J Biol Chem 271:11911-11919, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 11911-11919
-
-
Lin, A.W.1
Chang, C.C.2
McCormick, C.C.3
-
11
-
-
0028147767
-
Structure of the human cyclo-oxygenase-2 gene
-
Appleby SB, Ristimaki A, Neilson K, Narko K, Hla T: Structure of the human cyclo-oxygenase-2 gene. Biochem J 302:723-727, 1994.
-
(1994)
Biochem J
, vol.302
, pp. 723-727
-
-
Appleby, S.B.1
Ristimaki, A.2
Neilson, K.3
Narko, K.4
Hla, T.5
-
12
-
-
0028174061
-
Function and activation of NF-kappa B in the immune system
-
Baeuerle PA, Henkel T: Function and activation of NF-kappa B in the immune system. Annu Rev Immunol 12:141-179, 1994.
-
(1994)
Annu Rev Immunol
, vol.12
, pp. 141-179
-
-
Baeuerle, P.A.1
Henkel, T.2
-
13
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-.B activity
-
Karin M, Ben-Neriah Y: Phosphorylation meets ubiquitination: the control of NF-.B activity. Annu Rev Immunol 18:621-663, 2000.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
14
-
-
0028170816
-
Structure, regulation and function of NF-.B
-
Siebenlist U, Franzoso G, Brown K: Structure, regulation and function of NF-.B. Annu Rev Cell Biol 10:405-455, 1994.
-
(1994)
Annu Rev Cell Biol
, vol.10
, pp. 405-455
-
-
Siebenlist, U.1
Franzoso, G.2
Brown, K.3
-
15
-
-
0035164415
-
Toll-like receptor-mediated NF-.B activation: A phyloge-netically conserved paradigm in innate immunity
-
Zhang G, Ghosh S: Toll-like receptor-mediated NF-.B activation: a phyloge-netically conserved paradigm in innate immunity. J Clin Invest 107:13-19, 2001.
-
(2001)
J Clin Invest
, vol.107
, pp. 13-19
-
-
Zhang, G.1
Ghosh, S.2
-
16
-
-
0027144465
-
Protein tyrosine kinase activation is required for lipopolysaccharide induction of cytokines in human blood monocytes
-
Geng Y, Zhang B, Lotz M: Protein tyrosine kinase activation is required for lipopolysaccharide induction of cytokines in human blood monocytes. J Immunol 151:6692-6700, 1993.
-
(1993)
J Immunol
, vol.151
, pp. 6692-6700
-
-
Geng, Y.1
Zhang, B.2
Lotz, M.3
-
17
-
-
0030615201
-
Nuclear factor-kappa B: A pivotal transcription factor in chronic inflammatory diseases
-
Barnes PJ, Karin M: Nuclear factor-kappa B: a pivotal transcription factor in chronic inflammatory diseases. N Engl J Med 336:1066-1071, 1997.
-
(1997)
N Engl J Med
, vol.336
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
18
-
-
43749091527
-
Gastrointestinal and cardiovascular risks of nonsteroidal anti-inflammatory drugs
-
Jones R, Rubin G, Berenbaum F, Scheiman J: Gastrointestinal and cardiovascular risks of nonsteroidal anti-inflammatory drugs. Am J Med 121: 464-474, 2008.
-
(2008)
Am J Med
, vol.121
, pp. 464-474
-
-
Jones, R.1
Rubin, G.2
Berenbaum, F.3
Scheiman, J.4
-
19
-
-
62749098228
-
Denbinobin inhibits nuclear factor-kB and induces apoptosis via reactive oxygen species generation in human leukemic cells
-
Sanchez-Duffhues G, Calzado MA, de Vinuesa AG, Appendino G, Fiebich BL, Loock U, Lefarth-Risse A, Krohn K, Munoz E: Denbinobin inhibits nuclear factor-kB and induces apoptosis via reactive oxygen species generation in human leukemic cells. Biochem Pharmacol 77:1401-1409, 2009.
-
(2009)
Biochem Pharmacol
, vol.77
, pp. 1401-1409
-
-
Sanchez-Duffhues, G.1
Calzado, M.A.2
De Vinuesa, A.G.3
Appendino, G.4
Fiebich, B.L.5
Loock, U.6
Lefarth-Risse, A.7
Krohn, K.8
Munoz, E.9
-
20
-
-
0032828162
-
Anti-oxidant principles from Ephemerantha lonchophylla
-
Chen HY, Shiao MS, Huang YL, Shen CC, Lin YL, Kuo YH, Chen CC: Anti-oxidant principles from Ephemerantha lonchophylla. J Nat Prod 62:1225-1227, 1999.
-
(1999)
J Nat Prod
, vol.62
, pp. 1225-1227
-
-
Chen, H.Y.1
Shiao, M.S.2
Huang, Y.L.3
Shen, C.C.4
Lin, Y.L.5
Kuo, Y.H.6
Chen, C.C.7
-
21
-
-
54249113934
-
Denbinobin induces apoptosis by apoptosis-inducing factor releasing and DNA damage in human colorectal cancer HCT-116 cells
-
Chen TH, Pan SL, Guh JH, Chen CC, Huang YT, Pai HC, Teng CM: Denbinobin induces apoptosis by apoptosis-inducing factor releasing and DNA damage in human colorectal cancer HCT-116 cells. Naunyn Schmiedebergs Arch Pharmacol 378:447-457, 2008.
-
(2008)
Naunyn Schmiedebergs Arch Pharmacol
, vol.378
, pp. 447-457
-
-
Chen, T.H.1
Pan, S.L.2
Guh, J.H.3
Chen, C.C.4
Huang, Y.T.5
Pai, H.C.6
Teng, C.M.7
-
22
-
-
0028901805
-
In vitro and in vivo antitumoral phenanthrenes from the aerial parts of Dendrobium nobile
-
Lee YH, Park JD, Back NI, Kim SI, Ahn BZ: In vitro and in vivo antitumoral phenanthrenes from the aerial parts of Dendrobium nobile. Planta Med 61: 178-180, 1995.
-
(1995)
Planta Med
, vol.61
, pp. 178-180
-
-
Lee, Y.H.1
Park, J.D.2
Back, N.I.3
Kim, S.I.4
Ahn, B.Z.5
-
23
-
-
0034868490
-
Two phenanthraquinones from Dendrobium moniliforme
-
Lin TH, Chang SJ, Chen CC, Wang JP, Tsao LT: Two phenanthraquinones from Dendrobium moniliforme. J Nat Prod 64:1084-1086, 2001.
-
(2001)
J Nat Prod
, vol.64
, pp. 1084-1086
-
-
Lin, T.H.1
Chang, S.J.2
Chen, C.C.3
Wang, J.P.4
Tsao, L.T.5
-
24
-
-
0030799810
-
(j)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB
-
Lin YL, Lin JK: (j)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB. Mol Pharmacol 52:465-472, 1997.
-
(1997)
Mol Pharmacol
, vol.52
, pp. 465-472
-
-
Lin, Y.L.1
Lin, J.K.2
-
25
-
-
33751002989
-
ERK1/2 and p38-MAPK signaling pathways, through MSK1, are involved in NF-.B transactivation during oxidative stress in skeletal myoblasts
-
Kefaloyianni E, Gaitanaki C, Beis I: ERK1/2 and p38-MAPK signaling pathways, through MSK1, are involved in NF-.B transactivation during oxidative stress in skeletal myoblasts. Cell Signal 18:2238-2251, 2006.
-
(2006)
Cell Signal
, vol.18
, pp. 2238-2251
-
-
Kefaloyianni, E.1
Gaitanaki, C.2
Beis, I.3
-
26
-
-
29144511607
-
MAPK signalling pathways as molecular targets for anti-inflammatory therapyYfrom molecular mechanisms to therapeutic benefits
-
Kaminska B: MAPK signalling pathways as molecular targets for anti-inflammatory therapyYfrom molecular mechanisms to therapeutic benefits. Biochim Biophys Acta 1754:253-262, 2005.
-
(2005)
Biochim Biophys Acta
, vol.1754
, pp. 253-262
-
-
Kaminska, B.1
-
27
-
-
20344391974
-
Molecular mechanisms of denbinobin-induced anti-tumorigenesis effect in colon cancer cells
-
Yang KC, Uen YH, Suk FM, Liang YC, Wang YJ, Ho YS, Li IH, Lin SY: Molecular mechanisms of denbinobin-induced anti-tumorigenesis effect in colon cancer cells. World J Gastroenterol 11:3040-3045, 2005.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 3040-3045
-
-
Yang, K.C.1
Uen, Y.H.2
Suk, F.M.3
Liang, Y.C.4
Wang, Y.J.5
Ho, Y.S.6
Li, I.H.7
Lin, S.Y.8
-
28
-
-
0034129463
-
Antiplatelet aggregation principles from Ephemerantha lonchophylla
-
Chen CC, Huang YL, Teng CM: Antiplatelet aggregation principles from Ephemerantha lonchophylla. Planta Med 66:372-374, 2000.
-
(2000)
Planta Med
, vol.66
, pp. 372-374
-
-
Chen, C.C.1
Huang, Y.L.2
Teng, C.M.3
-
29
-
-
70350303589
-
Combined treatment with denbinobin and Fas ligand has a synergistic cytotoxic effect in human pancreatic adenocarcinoma BxPC-3 cells
-
Yang CR, Guh JH, Teng CM, Chen CC, Chen PH: Combined treatment with denbinobin and Fas ligand has a synergistic cytotoxic effect in human pancreatic adenocarcinoma BxPC-3 cells. Br J Pharmacol 157:1175-1185, 2009.
-
(2009)
Br J Pharmacol
, vol.157
, pp. 1175-1185
-
-
Yang, C.R.1
Guh, J.H.2
Teng, C.M.3
Chen, C.C.4
Chen, P.H.5
-
30
-
-
0028911559
-
Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock
-
Wu CC, Chen SJ, Szabo C, Thiemermann C, Vane JR: Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock. Br J Pharmacol 114:1666-1672, 1995.
-
(1995)
Br J Pharmacol
, vol.114
, pp. 1666-1672
-
-
Wu, C.C.1
Chen, S.J.2
Szabo, C.3
Thiemermann, C.4
Vane, J.R.5
-
31
-
-
0031985033
-
Nonselective versus selective inhibition of inducible nitric oxide synthase in experimental endotoxic shock
-
Liaudet L, Rosselet A, Schaller MD, Market M, Perret C, Feihl F: Nonselective versus selective inhibition of inducible nitric oxide synthase in experimental endotoxic shock. J Infect Dis 177:127-132, 1998.
-
(1998)
J Infect Dis
, vol.177
, pp. 127-132
-
-
Liaudet, L.1
Rosselet, A.2
Schaller, M.D.3
Market, M.4
Perret, C.5
Feihl, F.6
-
32
-
-
62249181657
-
Reactive oxygen species- and nitric oxideYmediated lung inflammation and mitochondria dysfunction in wild-type and iNOS-deficient mice exposed to diesel exhaust particles
-
Zhao H, Ma JK, Barger MW, Mercer RR, Millecchia L, Schwegler-Berry D, Castranova V, Ma JY: Reactive oxygen species- and nitric oxideYmediated lung inflammation and mitochondria dysfunction in wild-type and iNOS-deficient mice exposed to diesel exhaust particles. J Toxicol Environ Health A 72:560-570, 2009.
-
(2009)
J Toxicol Environ Health A
, vol.72
, pp. 560-570
-
-
Zhao, H.1
Ma, J.K.2
Barger, M.W.3
Mercer, R.R.4
Millecchia, L.5
Schwegler-Berry, D.6
Castranova, V.7
Ma, J.Y.8
-
33
-
-
57449089960
-
Helminth antigen-based strategy to ameliorate inflammation in an experimental model of colitis
-
Motomura Y, Wang H, Deng Y, El-Sharkawy RT, Verdu EF, Khan WI: Helminth antigen-based strategy to ameliorate inflammation in an experimental model of colitis. Clin Exp Immunol 155:88-95, 2009.
-
(2009)
Clin Exp Immunol
, vol.155
, pp. 88-95
-
-
Motomura, Y.1
Wang, H.2
Deng, Y.3
El-Sharkawy, R.T.4
Verdu, E.F.5
Khan, W.I.6
-
34
-
-
0035829842
-
Early goal-directed therapy in the treatment of severe sepsis and septic shock
-
Early Goal-Directed Therapy Collaborative Group
-
Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M: Early Goal-Directed Therapy Collaborative Group: Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345:1368-1377, 2001.
-
(2001)
N Engl J Med
, vol.345
, pp. 1368-1377
-
-
Rivers, E.1
Nguyen, B.2
Havstad, S.3
Ressler, J.4
Muzzin, A.5
Knoblich, B.6
Peterson, E.7
Tomlanovich, M.8
-
35
-
-
22944434894
-
Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors
-
Mollace V, Muscoli C, Masini E, Cuzzocrea S, Salvemini D: Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors. Pharmacol Rev 57:217-252, 2005.
-
(2005)
Pharmacol Rev
, vol.57
, pp. 217-252
-
-
Mollace, V.1
Muscoli, C.2
Masini, E.3
Cuzzocrea, S.4
Salvemini, D.5
-
36
-
-
0035104119
-
LPS induction of gene expression in human monocytes
-
Guha M, Mackman N: LPS induction of gene expression in human monocytes. Cell Signal 13:85-94, 2001.
-
(2001)
Cell Signal
, vol.13
, pp. 85-94
-
-
Guha, M.1
MacKman, N.2
-
37
-
-
0037032817
-
Mitogen-activated protein kinase pathways mediated by ERK JNK and p38 protein kinases
-
Johnson GL, Lapadat R: Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298:1911-1912, 2002.
-
(2002)
Science
, vol.298
, pp. 1911-1912
-
-
Johnson, G.L.1
Lapadat, R.2
-
38
-
-
0027939931
-
Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase
-
Xie QW, Kashiwabara Y, Nathan C: Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase. J Biol Chem 269:4705-4508, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 4705-4508
-
-
Xie, Q.W.1
Kashiwabara, Y.2
Nathan, C.3
-
39
-
-
33749496917
-
IL-1beta, an immediate early protein secreted by activated microglia, induces iNOS/NO in C6 astrocytoma cells through p38 MAPK and NF-kappaB pathways
-
Kim YJ, Hwang SY, Oh ES, Oh S, Han IO: IL-1beta, an immediate early protein secreted by activated microglia, induces iNOS/NO in C6 astrocytoma cells through p38 MAPK and NF-kappaB pathways. J Neurosci Res 84:1037-1046, 2006.
-
(2006)
J Neurosci Res
, vol.84
, pp. 1037-1046
-
-
Kim, Y.J.1
Hwang, S.Y.2
Oh, E.S.3
Oh, S.4
Han, I.O.5
-
40
-
-
0029919991
-
Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice
-
Haziot A, Ferrero E, Kontgen F, Hijiya N, Yamamoto S, Silver J, Stewart CL, Goyert SM: Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice. Immunity 4:407-414, 1996.
-
(1996)
Immunity
, vol.4
, pp. 407-414
-
-
Haziot, A.1
Ferrero, E.2
Kontgen, F.3
Hijiya, N.4
Yamamoto, S.5
Silver, J.6
Stewart, C.L.7
Goyert, S.M.8
-
41
-
-
77649184739
-
The regulation of IL-10 production by immune cells
-
Saraiva M, O'Garra A: The regulation of IL-10 production by immune cells. Nat Rev Immunol 10:170-181, 2010.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 170-181
-
-
Saraiva, M.1
O'Garra, A.2
|