Agonist-induced internalisation of the glucagon-like peptide-1 receptor is mediated by the Gαq pathway

Biochemical Pharmacology

Volumn 93, Issue 1, 2015, Pages 72-84

  Thompson, Aiysha ^a   Kanamarlapudi, Venkateswarlu ^a  

^a SWANSEA UNIVERSITY   (United Kingdom)

Author keywords

Endocytosis; G protein coupled receptor (GPCR); Gaq pathway; GLP 1 receptor (GLP 1R); Glucagon like peptide 1 (GLP 1)

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; MITOGEN ACTIVATED PROTEIN KINASE 1; GLUCAGON LIKE PEPTIDE 1; GLUCAGON RECEPTOR; GLUCAGON-LIKE PEPTIDE-1 RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT;

ARTICLE; CAMP ASSAY; CAVEOLA; CELL CULTURE; CELL LYSATE; CONTROLLED STUDY; ENDOCYTOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; INSULIN RELEASE; LUCIFERASE ASSAY; NONHUMAN; PANCREAS ISLET BETA CELL; POINT MUTATION; SITE DIRECTED MUTAGENESIS; STIMULATION; AGONISTS; DOSE RESPONSE; DRUG EFFECTS; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY;

DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCYTOSIS; GLUCAGON-LIKE PEPTIDE 1; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HEK293 CELLS; HUMANS; RECEPTORS, GLUCAGON;

EID: 84919740425     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2014.10.015     Document Type: Article

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