2′,3′-cAMP, 3′-AMP, 2′-AMP and adenosine inhibit TNF-α and CXCL10 production from activated primary murine microglia via A2A receptors

Brain Research

Volumn 1594, Issue , 2015, Pages 27-35

  Newell, Elizabeth A ^a   Exo, Jennifer L ^a   Verrier, Jonathan D ^b   Jackson, Travis C ^a   Gillespie, Delbert G ^b   Janesko Feldman, Keri ^a   Kochanek, Patrick M ^a   Jackson, Edwin K ^b  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

2 ,3 cAMP; 2 AMP; 3 AMP; A2A receptors; Adenosine; Adenosine receptors; CXCL10; Primary microglia; TNF

Indexed keywords

2 CHLORO 6 N CYCLOPENTYLADENOSINE; 2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 2' ADENOSINE PHOSPHATE; 3' ADENOSINE PHOSPHATE; ADENOSINE; ADENOSINE 2',3' PHOSPHATE; ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A2 RECEPTOR; ADENOSINE PHOSPHATE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 9; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; RANTES; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 2',3'-CYCLIC AMP; ADENINE NUCLEOTIDE; ADENOSINE A2A RECEPTOR; CXCL10 PROTEIN, MOUSE;

ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; BRAIN DISEASE; CELL ACTIVATION; CYTOKINE PRODUCTION; LIMIT OF DETECTION; MICROGLIA; MOUSE; NONHUMAN; STATISTICAL SIGNIFICANCE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; METABOLISM;

MURINAE;

ADENINE NUCLEOTIDES; ADENOSINE; ADENOSINE MONOPHOSPHATE; ANIMALS; CELLS, CULTURED; CHEMOKINE CXCL10; MICE; MICE, INBRED C57BL; MICROGLIA; RECEPTOR, ADENOSINE A2A; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84919658255     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2014.10.059     Document Type: Article

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