Etanercept attenuates traumatic brain injury in rats by reducing early microglial expression of tumor necrosis factor-α

BMC Neuroscience

Volumn 14, Issue , 2013, Pages

  Chio, Chung Ching ^a   Chang, Chin Hong ^a   Wang, Che Chuan ^a   Cheong, Chong Un ^a   Chao, Chien Ming ^a   Cheng, Bor Chih ^a,c   Yang, Chung Zhing ^c   Chang, Ching Ping ^b  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b SOUTHERN TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Astrocyte; Microglia; Neuron; Traumatic brain injury; Tumor necrosis factor alpha

Indexed keywords

ETANERCEPT; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN ISCHEMIA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOFLUORESCENCE; MALE; MICROGLIA; NERVE CELL; NONHUMAN; RAT; TRAUMATIC BRAIN INJURY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BRAIN INJURIES; CALCIUM-BINDING PROTEINS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; IMMUNOGLOBULIN G; MALE; MICROFILAMENT PROTEINS; MICROGLIA; NERVE TISSUE PROTEINS; NERVOUS SYSTEM DISEASES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, TUMOR NECROSIS FACTOR; TETRAZOLIUM SALTS; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84874943964     PISSN: None     EISSN: 14712202     Source Type: Journal    
DOI: 10.1186/1471-2202-14-33     Document Type: Article

References (39)

1. Goodman JC, Robertson CS, Grossman RG, Narayan RK. Elevation of tumor necrosis factor in head injury. J Neuroimmunol 1990, 30(2-3):213-217.
2. Ross SA, Halliday MI, Campbell GC, Byrnes DP, Rowlands BJ. The presence of tumour necrosis factor in CSF and plasma after severe head injury. Br J Neurosurg 1994, 8(4):419-425. 10.3109/02688699408995109, 7811406.
3. Taupin V, Toulmond S, Serrano A, Benavides J, Zavala F. Increase in IL-6, IL-1 and TNF levels in rat brain following traumatic lesion. Influence of pre- and post-traumatic treatment with Ro5 4864, a peripheral-type (p site) benzodiazepine ligand. J Neuroimmunol 1993, 42(2):177-185. 10.1016/0165-5728(93)90008-M, 8429103.
4. Yakovlev AG, Faden AI. Molecular biology of CNS injury. J Neurotrauma 1995, 12(5):767-777. 10.1089/neu.1995.12.767, 8594206.
5. Fan L, Young PR, Barone FC, Feuerstein GZ, Smith DH, McIntosh TK. Experimental brain injury induces differential expression of tumor necrosis factor-alpha mRNA in the CNS. Brain Res Mol Brain Res 1996, 36(2):287-291. 10.1016/0169-328X(95)00274-V, 8965649.
6. Shohami E, Gallily R, Mechoulam R, Bass R, Ben-Hur T. Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant. J Neuroimmunol 1997, 72(2):169-177. 10.1016/S0165-5728(96)00181-6, 9042110.
7. Knoblach SM, Faden AI. Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury. Exp Neurol 1998, 153(1):143-151. 10.1006/exnr.1998.6877, 9743576.
8. Chio CC, Lin JW, Chang MW, Wang CC, Kuo JR, Yang CZ, Chang CP. Therapeutic evaluation of etanercept in a model of traumatic brain injury. J Neurochem 2010, 115(4):921-929. 10.1111/j.1471-4159.2010.06969.x, 20796174.
9. Bezzi P, Volterra A. A neuron-glia signalling network in the active brain. Curr Opin Neurobiol 2001, 11(3):387-394. 10.1016/S0959-4388(00)00223-3, 11399439.
10. Perry SW, Dewhurst S, Bellizzi MJ, Gelbard HA. Tumor necrosis factor-alpha in normal and diseased brain: Conflicting effects via intraneuronal receptor crosstalk?. J Neurovirol 2002, 8(6):611-624. 10.1080/13550280290101021, 12476354.
11. Mclntosh TK, Noble L, Andrews B, Faden AI. Traumatic brain injury in the rat: characterization of a midline fluid-percussion model. Cent Nerv Syst Trauma 1987, 4:119-134.
12. Jones NC, Cardamone L, Williams JP, Salzberg MR, Myers D, O'Brien TJ. Experimental traumatic brain injury induces a pervasive hyperanxious phenotype in rats. J Neurotrauma 2008, 25(11):1367-1374. 10.1089/neu.2008.0641, 19061380.
13. Shohami E, Novikov M, Bass R. Long-term effect of HU-211, a novel non-competitive NMDA antagonist, on motor and memory functions after closed head injury in the rat. Brain Res 1995, 674(1):55-62. 10.1016/0006-8993(94)01433-I, 7773695.
14. Chang MW, Young MS, Lin MT. An inclined plane system with microcontroller to determine limb motor function of laboratory animals. J Neurosci Methods 2008, 168(1):186-194. 10.1016/j.jneumeth.2007.09.013, 17953994.
15. Wang Y, Lin SZ, Chiou AL, Williams LR, Hoffer BJ. Glial cell line-derived neurotrophic factor protects against ischemia-induced injury in the cerebral cortex. J Neurosci 1997, 17(11):4341-4348.
16. Li B, Mahmood A, Lu D, Wu H, Xiong Y, Qu C, Chopp M. Simvastatin attenuates microglial cells and astrocyte activation and decreases interleukin-1beta level after traumatic brain injury. Neurosurgery 2009, 65(1):179-185. discussion 185-186, 10.1227/01.NEU.0000346272.76537.DC, 2749520, 19574840.
17. Dirnagl U, Iadecola C, Moskowitz MA. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci 1999, 22(9):391-397. 10.1016/S0166-2236(99)01401-0, 10441299.
18. Feuerstein G, Wang X, Barone FC. Cytokines in brain ischemia-the role of TNF alpha. Cell Mol Neurobiol 1998, 18(6):695-701. 10.1023/A:1020226020062, 9876875.
19. Minghetti L, Levi G. Microglia as effector cells in brain damage and repair: focus on prostanoids and nitric oxide. Prog Neurobiol 1998, 54(1):99-125. 10.1016/S0301-0082(97)00052-X, 9460796.
20. Batchelor PE, Liberatore GT, Wong JY, Porritt MJ, Frerichs F, Donnan GA, Howells DW. Activated macrophages and microglia induce dopaminergic sprouting in the injured striatum and express brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor. J Neurosci 1999, 19(5):1708-1716.
21. Hanisch UK. Microglia as a source and target of cytokines. Glia 2002, 40(2):140-155. 10.1002/glia.10161, 12379902.
22. Bermpohl D, You Z, Lo EH, Kim HH, Whalen MJ. TNF alpha and Fas mediate tissue damage and functional outcome after traumatic brain injury in mice. J Cereb Blood Flow Metab 2007, 27(11):1806-1818. 10.1038/sj.jcbfm.9600487, 17406655.
23. Maier B, Lehnert M, Laurer HL, Mautes AE, Steudel WI, Marzi I. Delayed elevation of soluble tumor necrosis factor receptors p75 and p55 in cerebrospinal fluid and plasma after traumatic brain injury. Shock 2006, 26(2):122-127. 10.1097/01.shk.0000223127.41641.f4, 16878018.
24. Neumann H, Schweigreiter R, Yamashita T, Rosenkranz K, Wekerle H, Barde YA. Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a rho-dependent mechanism. J Neurosci 2002, 22(3):854-862.
25. Williams AJ, Wei HH, Dave JR, Tortella FC. Acute and delayed neuroinflammatory response following experimental penetrating ballistic brain injury in the rat. J Neuroinflammation 2007, 4:17. 10.1186/1742-2094-4-17, 1933533, 17605820.
26. Bell MJ, Kochanek PM, Doughty LA, Carcillo JA, Adelson PD, Clark RS, Wisniewski SR, Whalen MJ, DeKosky ST. Interleukin-6 and interleukin-10 in cerebrospinal fluid after severe traumatic brain injury in children. J Neurotrauma 1997, 14(7):451-457. 10.1089/neu.1997.14.451, 9257663.
27. Csuka E, Morganti-Kossmann MC, Lenzlinger PM, Joller H, Trentz O, Kossmann T. IL-10 levels in cerebrospinal fluid and serum of patients with severe traumatic brain injury: relationship to IL-6, TNF-alpha, TGF-beta1 and blood-brain barrier function. J Neuroimmunol 1999, 101(2):211-221. 10.1016/S0165-5728(99)00148-4, 10580806.
28. Holmin S, Soderlund J, Biberfeld P, Mathiesen T. Intracerebral inflammation after human brain contusion. Neurosurgery 1998, 42(2):291-298. discussion 298-299, 10.1097/00006123-199802000-00047, 9482179.
29. McClain C, Cohen D, Phillips R, Ott L, Young B. Increased plasma and ventricular fluid interleukin-6 levels in patients with head injury. J Lab Clin Med 1991, 118(3):225-231.
30. Holmin S, Schalling M, Hojeberg B, Nordqvist AC, Skeftruna AK, Mathiesen T. Delayed cytokine expression in rat brain following experimental contusion. J Neurosurg 1997, 86(3):493-504. 10.3171/jns.1997.86.3.0493, 9046307.
31. Knoblach SM, Fan L, Faden AI. Early neuronal expression of tumor necrosis factor-alpha after experimental brain injury contributes to neurological impairment. J Neuroimmunol 1999, 95(1-2):115-125.
32. Shohami E, Novikov M, Bass R, Yamin A, Gallily R. Closed head injury triggers early production of TNF alpha and IL-6 by brain tissue. J Cereb Blood Flow Metab 1994, 14(4):615-619. 10.1038/jcbfm.1994.76, 8014208.
33. Stahel PF, Shohami E, Younis FM, Kariya K, Otto VI, Lenzlinger PM, Grosjean MB, Eugster HP, Trentz O, Kossmann T, others Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines. J Cereb Blood Flow Metab 2000, 20(2):369-380. others.
34. Stover JF, Schoning B, Beyer TF, Woiciechowsky C, Unterberg AW. Temporal profile of cerebrospinal fluid glutamate, interleukin-6, and tumor necrosis factor-alpha in relation to brain edema and contusion following controlled cortical impact injury in rats. Neurosci Lett 2000, 288(1):25-28. 10.1016/S0304-3940(00)01187-3, 10869807.
35. Scherbel U, Raghupathi R, Nakamura M, Saatman KE, Trojanowski JQ, Neugebauer E, Marino MW, McIntosh TK. Differential acute and chronic responses of tumor necrosis factor-deficient mice to experimental brain injury. Proc Natl Acad Sci U S A 1999, 96(15):8721-8726. 10.1073/pnas.96.15.8721, 17583, 10411942.
36. Shohami E, Ginis I, Hallenbeck JM. Dual role of tumor necrosis factor alpha in brain injury. Cytokine Growth Factor Rev 1999, 10(2):119-130. Review, 10.1016/S1359-6101(99)00008-8, 10743503.
37. Oshima T, Lee S, Sato A, Oda S, Hirasawa H, Yamashita T. TNF-alpha contributes to axonal sprouting and functional recovery following traumatic brain injury. Brain Res 2009, 1290:102-110.
38. Francis J, Chu Y, Johnson AK, Weiss RM, Felder RB. Acute myocardial infarction induces hypothalamic cytokine synthesis. Am J Physiol Heart Circ Physiol 2004, 286(6):H2264-H2271. 10.1152/ajpheart.01072.2003, 15148057.
39. Bao F, Fleming JC, Golshani R, Pearse DD, Kasabov L, Brown A, Weaver LC. A selective phosphodiesterase-4 inhibitor reduces leukocyte infiltration, oxidative processes, and tissue damage after spinal cord injury. J Neurotrauma 2011, 28(6):1035-1049. 10.1089/neu.2010.1575, 3113414, 21355819.