MiR-141 regulates TGF-β1-induced epithelial-mesenchymal transition through repression of HIPK2 expression in renal tubular epithelial cells

International Journal of Molecular Medicine

Volumn 35, Issue 2, 2015, Pages 311-318

  Huang, Yuanhang ^a,b   Tong, Junrong ^b   He, Feng ^b   Yu, Xinpei ^c   Fan, Liming ^b   Hu, Jing ^b   Tan, Jiangping ^b   Chen, Zhengliang ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b Department of Nephrology ^*  (China)

^c Geriatric Infection and Organ Function Support Laboratory Guanzhou General Hospital of Guanzhou Military Command   (China)

Author keywords

Epithelial mesenchymal transition; FSP1; HIPK2; MicroRNA; MiR 141; Renal tubulointerstitial fibrosis; TGF 1

Indexed keywords

CALVASCULIN; HOMEODOMAIN INTERACTING PROTEIN KINASE 2; MICRORNA 141; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN; VIMENTIN; CADHERIN; CALCIUM BINDING PROTEIN; CARRIER PROTEIN; FSP1 PROTEIN, HUMAN; HIPK2 PROTEIN, HUMAN; MICRORNA; MIRN141 MICRORNA, HUMAN; PROTEIN SERINE THREONINE KINASE; TGFB1 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME REPRESSION; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY FIBROSIS; KIDNEY TUBULE EPITHELIUM; PROTEIN EXPRESSION; THERAPY; UPREGULATION; BIOSYNTHESIS; CELL LINE; EPITHELIUM CELL; FIBROSIS; GENE EXPRESSION REGULATION; KIDNEY DISEASE; KIDNEY TUBULE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

CADHERINS; CALCIUM-BINDING PROTEINS; CARRIER PROTEINS; CELL LINE; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FIBROSIS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; KIDNEY DISEASES; KIDNEY TUBULES; MICRORNAS; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION; VIMENTIN;

EID: 84919608870     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.2008     Document Type: Article

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