메뉴 건너뛰기




Volumn 8, Issue 6, 2009, Pages 3006-3019

Proteomic and functional analyses reveal a dual molecular mechanism underlying arsenic-induced apoptosis in human multiple myeloma cells

Author keywords

14 3 3 ; Arsenic trioxide; Heat shock proteins; Multiple myeloma; Proteomics

Indexed keywords

ARSENIC TRIOXIDE; HEAT SHOCK PROTEIN 90; PROTEASOME; SMALL INTERFERING RNA; STRATIFIN; UBIQUITIN;

EID: 67049115481     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr9001004     Document Type: Article
Times cited : (55)

References (44)
  • 4
    • 42449114035 scopus 로고    scopus 로고
    • Multiple myeloma
    • Kyle, R. A.; Rajkumar, S. V. Multiple myeloma. Blood 2008, 15, 2962-2972.
    • (2008) Blood , vol.15 , pp. 2962-2972
    • Kyle, R.A.1    Rajkumar, S.V.2
  • 6
    • 0034142368 scopus 로고    scopus 로고
    • Arsenic induces apoptosis of multidrug-resistant human myeloid leukemia cells thin express Bcr-Abl or overexpress MDR, MRP, Bcl-2, or Bcl-x(L)
    • Perkins, C.; Kim, C. N.; Fang, G.; Bhalla, K. N. Arsenic induces apoptosis of multidrug-resistant human myeloid leukemia cells that express Bcr-Abl or overexpress MDR, MRP, Bcl-2, or Bcl-xL. Blood 2000, 95, 1014-1022. (Pubitemid 30062726)
    • (2000) Blood , vol.95 , Issue.3 , pp. 1014-1022
    • Perkins, C.1    Kim, C.N.2    Fang, G.3    Bhalla, K.N.4
  • 7
    • 0032773828 scopus 로고    scopus 로고
    • Induction of apoptosis and inhibition of human gastric cancer MGC-803 cell growth by arsenic trioxide
    • DOI 10.1016/S0959-8049(99)00106-9, PII S0959804999001069
    • Zhang, T. C.; Cao, E. H.; Li, J. F.; Ma, W.; Qin, J. F. Induction of apoptosis and inhibition of human gastric cancer MGC-803 cell growth by arsenic trioxide. Eur. J. Cancer 1999, 35, 1258-1263. (Pubitemid 29359187)
    • (1999) European Journal of Cancer , vol.35 , Issue.8 , pp. 1258-1263
    • Zhang, T.-C.1    Cao, E.-H.2    Li, J.-F.3    Ma, W.4    Qin, J.-F.5
  • 9
    • 0033105268 scopus 로고    scopus 로고
    • Arsenic trioxide and melarsoprol induce apoptosis in plasma cell lines and in plasma cells from myeloma patients
    • Rousselot, P.; Labaume, S.; Marolleau, J. P.; Larghero, J.; Noguera, M. H.; Brouet, J. C.; Fermand, J. P. Arsenic trioxide and melarsoprol induce apoptosis in plasma cell lines and in plasma cells from myeloma patients. Cancer Res. 1999, 59, 1041-1048. (Pubitemid 29135964)
    • (1999) Cancer Research , vol.59 , Issue.5 , pp. 1041-1048
    • Rousselot, P.1    Labaume, S.2    Marolleau, J.-P.3    Larghero, J.4    Noguera, M.-H.5    Brouet, J.-C.6    Fermand, J.-P.7
  • 10
    • 0034212785 scopus 로고    scopus 로고
    • Arsenic trioxide-mediated growth inhibition in MC/CAR myeloma cells via cell cycle arrest in association with induction of cyclin-dependent kinase inhibitor, p21, and apoptosis
    • Park, W. H.; Seol, J. G.; Kim, E. S.; Hyun, J. M.; Jung, C. W.; Lee, C. C.; Kim, B. K.; Lee, Y. Y. Arsenic trioxide-mediated growth inhibition in MC/CAR myeloma cells via cell cycle arrest in association with induction of cyclin-dependent kinase inhibitor, p21, and apoptosis. Cancer Res. 2000, 60, 3065-3071. (Pubitemid 30395836)
    • (2000) Cancer Research , vol.60 , Issue.11 , pp. 3065-3071
    • Park, W.H.1    Seol, J.G.2    Kim, E.S.3    Hyun, J.M.4    Jung, C.W.5    Lee, C.C.6    Kim, B.K.7    Lee, Y.Y.8
  • 11
    • 33744532339 scopus 로고    scopus 로고
    • Sustained activation of c-jun-N-terminal kinase plays a critical role in arsenic trioxide-induced cell apoptosis in multiple myeloma cell lines
    • DOI 10.1111/j.1349-7006.2006.00199.x
    • Kajiguchi, T.; Yamamoto, K.; Iida, S.; Ueda, R.; Emi, N.; Naoe, T. Sustained activation of c-jun-N-terminal kinase plays a critical role in arsenic trioxide-induced cell apoptosis in multiple myeloma cell lines. Cancer Sci. 2006, 97, 540-545. (Pubitemid 43811597)
    • (2006) Cancer Science , vol.97 , Issue.6 , pp. 540-545
    • Kajiguchi, T.1    Yamamoto, K.2    Iida, S.3    Ueda, R.4    Emi, N.5    Naoe, T.6
  • 13
    • 3142715479 scopus 로고    scopus 로고
    • Phase 2 study of arsenic trioxide in patients with relapsed or refractory multiple myeloma
    • DOI 10.1111/j.1365-2141.2004.04941.x
    • Hussein, M. A.; Saleh, M.; Ravandi, F.; Mason, J.; Rifkin, R. M.; Ellison, R. Phase 2 study of arsenic trioxide in patients with relapsed or refractory multiple myeloma. Br. J. Hamaetol. 2004, 125, 470-476. (Pubitemid 38916192)
    • (2004) British Journal of Haematology , vol.125 , Issue.4 , pp. 470-476
    • Hussein, M.A.1    Saleh, M.2    Ravandi, F.3    Mason, J.4    Rifkin, R.M.5    Ellison, R.6
  • 15
    • 0142106346 scopus 로고    scopus 로고
    • Cellular stress and DNA damage invoke temporally distinct Mdm2, p53 and PML complexes and damage-specific nuclear relocalization
    • DOI 10.1242/jcs.00714
    • Kurki, S.; Latonen, L.; Laiho, M. Cellular stress and DNA damage invoke temporally distinct Mdm2, p53 and PML complexes and damage-specific nuclear relocalization. J. Cell Sci. 2003, 116, 3917-3925. (Pubitemid 37279307)
    • (2003) Journal of Cell Science , vol.116 , Issue.19 , pp. 3917-3925
    • Kurki, S.1    Latonen, L.2    Laiho, M.3
  • 17
    • 0042744800 scopus 로고    scopus 로고
    • Inhibition of NF-kB essentially contributes to arsenic-induced apoptosis
    • DOI 10.1182/blood-2002-04-1154
    • Mathas, S.; Lietz, A.; Janz, M.; Hinz, M.; Jundt, F.; Scheidereit, C.; Bommert, K.; Dorken, B. Inhibition of NF-kB essentially contributes to arsenic-induced apoptosis. Blood 2003, 102, 1028-1034. (Pubitemid 36917800)
    • (2003) Blood , vol.102 , Issue.3 , pp. 1028-1034
    • Mathas, S.1    Lietz, A.2    Janz, M.3    Hinz, M.4    Jundt, F.5    Scheidereit, C.6    Bommert, K.7    Dorken, B.8
  • 18
    • 0037507271 scopus 로고    scopus 로고
    • Promyelocytic leukemia protein (PML) functions as a glucocorticoid receptor co-activator by sequestering Daxx to the PML oncogenic domains (PODs) to enhance its transactivation potential
    • DOI 10.1074/jbc.M300387200
    • Lin, D. Y.; Lai, M. Z.; Ann, D. K.; Shih, H. M. Promyelocytic leukemia protein (PML) functions as a glucocorticoid receptor coactivator by sequestering Daxx to the PML oncogenic domains (PODs) to enhance its transactivation potential. J. Biol. Chem. 2003, 278, 15958-15965. (Pubitemid 36799714)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.18 , pp. 15958-15965
    • Lin, D.-Y.1    Lai, M.-Z.2    Ann, D.K.3    Shih, H.-M.4
  • 20
    • 29244451873 scopus 로고    scopus 로고
    • Gold(III) porphyrin 1a induced apoptosis by mitochondrial death pathways related to reactive oxygen species
    • DOI 10.1158/0008-5472.CAN-05-2867
    • Wang, Y.; He, Q. Y.; Sun, R. W.; Che, C. M.; Chiu, J. F. GoldIII porphyrin 1a induced apoptosis by mitochondrial death pathways related to reactive oxygen species. Cancer Res. 2005, 15, 11553-11564. (Pubitemid 41821714)
    • (2005) Cancer Research , vol.65 , Issue.24 , pp. 11553-11564
    • Wang, Y.1    He, Q.-Y.2    Sun, R.W.-Y.3    Che, C.-M.4    Chiu, J.-F.5
  • 21
    • 33646251378 scopus 로고    scopus 로고
    • Proteomic approach to study the cytotoxicity of dioscin (saponin)
    • Wang, Y.; Cheung, Y. H.; Yang, Z.; Chiu, J. F.; Che, C. M.; He, Q. Y. Proteomic approach to study the cytotoxicity of dioscin (saponin). Proteomics 2006, 6, 2422-2432.
    • (2006) Proteomics , vol.6 , pp. 2422-2432
    • Wang, Y.1    Cheung, Y.H.2    Yang, Z.3    Chiu, J.F.4    Che, C.M.5    He, Q.Y.6
  • 22
    • 33947231266 scopus 로고    scopus 로고
    • Proteomics approach to illustrate drug action mechanisms
    • DOI 10.2174/157016306780136763
    • Wang, Y.; Chiu, J. F.; He, Q. Y. Proteomics approach to illustrate drug action mechanisms. Curr. Drug Discov. Technol. 2006, 3, 199-209. (Pubitemid 46425956)
    • (2006) Current Drug Discovery Technologies , vol.3 , Issue.3 , pp. 199-209
    • Wang, Y.1    Chiu, J.-F.2    He, Q.-Y.3
  • 23
    • 39749155663 scopus 로고    scopus 로고
    • Modulation of gold(III) porphyrin 1a-induced apoptosis by mitogen-activated protein kinase signaling pathways
    • Wang, Y.; He, Q. Y.; Che, C. M.; Tsao, S. W.; Sun, R. W.; Chiu, J. F. Modulation of gold(III) porphyrin 1a-induced apoptosis by mitogen-activated protein kinase signaling pathways. Biochem. Pharmacol. 2008, 15, 1282-1291.
    • (2008) Biochem. Pharmacol. , vol.15 , pp. 1282-1291
    • Wang, Y.1    He, Q.Y.2    Che, C.M.3    Tsao, S.W.4    Sun, R.W.5    Chiu, J.F.6
  • 24
    • 48249095483 scopus 로고    scopus 로고
    • Proteomic analysis of chromium cytotoxicity in cultured rat lung epithelial cells
    • Lei, T.; He, Q. Y.; Cai, Z.; Zhou, Y.; Wang, Y. L.; Si, L. S.; Cai, Z.; Chiu, J. F. Proteomic analysis of chromium cytotoxicity in cultured rat lung epithelial cells. Proteomics 2008, 8, 2420-2429.
    • (2008) Proteomics , vol.8 , pp. 2420-2429
    • Lei, T.1    He, Q.Y.2    Cai, Z.3    Zhou, Y.4    Wang, Y.L.5    Si, L.S.6    Cai, Z.7    Chiu, J.F.8
  • 25
    • 18544376266 scopus 로고    scopus 로고
    • Vitamin C protects HL60 and U266 cells from arsenic toxicity
    • DOI 10.1182/blood-2003-03-0772
    • Karasavvas, N.; Cárcamo, J. M.; Stratis, G.; Golde, D. W. Vitamin C protects HL60 and U266 cells from arsenic toxicity. Blood 2005, 105, 4004-4012. (Pubitemid 40656149)
    • (2005) Blood , vol.105 , Issue.10 , pp. 4004-4012
    • Karasavvas, N.1    Carcamo, J.M.2    Stratis, G.3    Golde, D.W.4
  • 27
    • 33846067524 scopus 로고    scopus 로고
    • PANTHER version 6: Protein sequence and function evolution data with expanded representation of biological pathways
    • DOI 10.1093/nar/gkl869
    • Mi, H.; Guo, N.; Kejariwal, A.; Thomas, P. D. PANTHER version 6: protein sequence and function evolution data with expanded representation of biological pathways. Nucleic Acids Res. 2007, 35, D247-D252. (Pubitemid 46056208)
    • (2007) Nucleic Acids Research , vol.35 , Issue.SUPPL. 1
    • Mi, H.1    Guo, N.2    Kejariwal, A.3    Thomas, P.D.4
  • 29
    • 33846086800 scopus 로고    scopus 로고
    • STRING 7 - Recent developments in the integration and prediction of protein interactions
    • DOI 10.1093/nar/gkl825
    • von Mering, C.; Jensen, L. J.; Kuhn, M.; Chaffron, S.; Doerks, T.; Krüger, B.; Snel, B.; Bork, P. STRING 7 - recent developments in the integration and prediction of protein interactions. Nucleic Acids Res. 2007, 35, D358-D362. (Pubitemid 46056231)
    • (2007) Nucleic Acids Research , vol.35 , Issue.SUPPL. 1
    • Von Mering, C.1    Jensen, L.J.2    Kuhn, M.3    Chaffron, S.4    Doerks, T.5    Kruger, B.6    Snel, B.7    Bork, P.8
  • 30
    • 0030832988 scopus 로고    scopus 로고
    • Enhanced antisense effects resulting from an improved streptolysin-O protocol for oligodeoxynucleotide delivery into human leukaemia cells
    • Giles, R. V.; Grzybowski, J.; Spiller, D. G.; Tidd, D. M. Enhanced antisense effects resulting from an improved streptolysin-o protocol for oligodeoxynucleotide delivery into human leukaemia cells. Nucleosides Nucleotides 1997, 16, 1155-1163. (Pubitemid 27494443)
    • (1997) Nucleosides and Nucleotides , vol.16 , Issue.7-9 , pp. 1155-1163
    • Giles, R.V.1    Grzybowski, J.2    Spiller, D.G.3    Tidd, D.M.4
  • 31
    • 0032052790 scopus 로고    scopus 로고
    • Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells
    • DOI 10.1093/nar/26.7.1567
    • Giles, R. V.; Spiller, D. G.; Grzybowski, J.; Clark, R. E.; Nicklin, P.; Tidd, D. M. Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells. Nucleic Acids Res. 1998, 26, 1567-1575. (Pubitemid 28291789)
    • (1998) Nucleic Acids Research , vol.26 , Issue.7 , pp. 1567-1575
    • Giles, R.V.1    Spiller, D.G.2    Grzybowski, J.3    Clark, R.E.4    Nicklin, P.5    Tidd, D.M.6
  • 32
    • 41149088657 scopus 로고    scopus 로고
    • Streptolysin-O reversible permeabilisation is an effective method to transfect siRNAs into myeloma cells
    • Brito, J. L.; Davies, F. E.; Gonzalez, D.; Morgan, G. J. Streptolysin-O reversible permeabilisation is an effective method to transfect siRNAs into myeloma cells. J. Immunol. Methods 2008, 333, 147-155.
    • (2008) J. Immunol. Methods , vol.333 , pp. 147-155
    • Brito, J.L.1    Davies, F.E.2    Gonzalez, D.3    Morgan, G.J.4
  • 33
    • 0032170898 scopus 로고    scopus 로고
    • Arsenic trioxide and melarsoprol induce programmed cell death in myeloid leukemia cell lines and function in a PML and PML-RARa independent manner
    • Wang, Z. G.; Rivi, R.; Delva, L.; König, A.; Scheinberg, D. A.; Passerini, C. G.; Gabrilove, J.; Larrell, R. P.; Pandolfi, P. P. Arsenic trioxide and melarsoprol induce programmed cell death in myeloid leukemia cell lines and function in a PML and PML-RARa independent manner. Blood 1998, 92, 1497-1504. (Pubitemid 28406851)
    • (1998) Blood , vol.92 , Issue.5 , pp. 1497-1504
    • Wang, Z.-G.1    Rivi, R.2    Delva, L.3    Konig, A.4    Scheinberg, D.A.5    Gambacorti-Passerini, C.6    Gabrilove, J.L.7    Warrell Jr., R.P.8    Pandolfi, P.P.9
  • 34
    • 0031691443 scopus 로고    scopus 로고
    • Arsenic induces apoptosis in B-cell leukaemic cell lines in vitro: Activation of caspases and down-regulation of Bcl-2 protein
    • DOI 10.1046/j.1365-2141.1998.00869.x
    • Akao, Y.; Mizoguchi, H.; Kojima, S.; Naoe, T.; Ohishi, N.; Yagi, K. Arsenic induces apoptosis in B-cell leukemic cell lines in vitro: activation of caspases and down-regulation of Bcl-2 protein. Br. J. Hamaetol. 1998, 102, 1055-1060. (Pubitemid 28410539)
    • (1998) British Journal of Haematology , vol.102 , Issue.4 , pp. 1055-1060
    • Akao, Y.1    Mizoguchi, H.2    Kojima, S.3    Naoe, T.4    Ohishi, N.5    Yagi, K.6
  • 37
    • 33646926129 scopus 로고    scopus 로고
    • 14-3-3 proteins: A historic overview
    • DOI 10.1016/j.semcancer.2006.03.005, PII S1044579X06000253
    • Aitken, A. 14-3-3 proteins: A historic overview. Semin. Cancer. Biol. 2006, 16, 162-172. (Pubitemid 43796128)
    • (2006) Seminars in Cancer Biology , vol.16 , Issue.3 , pp. 162-172
    • Aitken, A.1
  • 38
    • 39749094444 scopus 로고    scopus 로고
    • Cellular functions of 14-3-3zeta in apoptosis and cell adhesion emphasize its oncogenic character
    • DOI 10.1038/sj.onc.1210742, PII 1210742
    • Niemantsverdriet, M.; Wagner, K.; Visser, M.; Backendorf, C. Cellular functions of 14-3-3zeta in apoptosis and cell adhesion emphasize its oncogenic character. Oncogene 2008, 27, 1315-1319. (Pubitemid 351294692)
    • (2008) Oncogene , vol.27 , Issue.9 , pp. 1315-1319
    • Niemantsverdriet, M.1    Wagner, K.2    Visser, M.3    Backendorf, C.4
  • 42
    • 33751172982 scopus 로고    scopus 로고
    • Aggresome induction by proteasome inhibitor bortezomib and tubulin hyperacetylation by tubulin deacetylase (TDAC) inhibitor LBH589 are synergistic in myeloma cells
    • DOI 10.1182/blood-2006-04-016055
    • Catley, L.; Weisberg, E.; Kiziltepe, T.; Tai, Y. T.; Hideshima, T.; Neri, P.; Tassone, P.; Atadja, P.; Chauhan, D.; Munshi, N. C.; Anderson, K. C. Aggresome induction by proteasome inhibitor bortezomib and tubulin hyperacetylation by tubulin deacetylase (TDAC) inhibitor LBH589 are synergistic in myeloma cells. Blood 2006, 108, 3441-3449. (Pubitemid 44776885)
    • (2006) Blood , vol.108 , Issue.10 , pp. 3441-3449
    • Catley, L.1    Weisberg, E.2    Kiziltepe, T.3    Tai, Y.-T.4    Hideshima, T.5    Neri, P.6    Tassone, P.7    Atadja, P.8    Chauhan, D.9    Munshi, N.C.10    Anderson, K.C.11
  • 43
    • 0033534750 scopus 로고    scopus 로고
    • Proteasome inhibitors MG132 and lactacystin hyperphosphorylate HSF1 and induce hsp70 and hsp27 expression
    • DOI 10.1006/bbrc.1998.9840
    • Kim, D.; Kim, S. H.; Li, G. C. Proteasome inhibitors MG132 and lactacystin hyperphosphorylate HSF1 and induce hsp70 and hsp27 expression. Biochem. Biophys. Res. Commun. 1999, 254, 264-268. (Pubitemid 29292051)
    • (1999) Biochemical and Biophysical Research Communications , vol.254 , Issue.1 , pp. 264-268
    • Kim, D.1    Kim, S.-H.2    Li, G.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.