Arsenic trioxide induces autophagy and apoptosis in human glioma cells in vitro and in vivo through downregulation of survivin

Journal of Molecular Medicine

Volumn 89, Issue 9, 2011, Pages 927-941

  Chiu, Hui Wen ^a   Ho, Yuan Soon ^c,d   Wang, Ying Jan ^a,b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Arsenic trioxide; Autophagy; Cancer; Cell cycle; Cell death; Glioma; Survivin

Indexed keywords

ARSENIC TRIOXIDE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SURVIVIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL CYCLE; CELL VIABILITY; DOWN REGULATION; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; ARSENICALS; AUTOPHAGY; CELL CYCLE; CELL SURVIVAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GLIOMA; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MALE; MICE; MICE, SCID; MITOGEN-ACTIVATED PROTEIN KINASES; OXIDES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TUMOR BURDEN;

EID: 80052467543     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-011-0763-1     Document Type: Article

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