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Volumn 33, Issue 2, 2015, Pages 507-514

CLC-3 channels in cancer (Review)

Author keywords

Apoptosis; Cancer; Chemotherapeutic resistance; Chloride channel; CLC 3; Proliferation

Indexed keywords

ANION CHANNEL; BUFADIENOLIDE DERIVATIVE; CHLOROTOXIN; CLC 3 PROTEIN; SCORPION VENOM; UNCLASSIFIED DRUG; VOLTAGE GATED CHLORIDE CHANNEL; VOLUME REGULATED ANION CHANNEL; ANTINEOPLASTIC AGENT; CHLORIDE CHANNEL; CLC-3 CHANNEL;

EID: 84919432479     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3615     Document Type: Review
Times cited : (50)

References (102)
  • 1
    • 0037049999 scopus 로고    scopus 로고
    • Cardiac channelopathies
    • Marban E: Cardiac channelopathies. Nature 415: 213-218, 2002.
    • (2002) Nature , vol.415 , pp. 213-218
    • Marban, E.1
  • 2
    • 70349667578 scopus 로고    scopus 로고
    • Skeletal muscle channelopathies: New insights into the periodic paralyses and nondystrophic myotonias
    • Platt D and Griggs R: Skeletal muscle channelopathies: new insights into the periodic paralyses and nondystrophic myotonias. Curr Opin Neurol 22: 524-531, 2009.
    • (2009) Curr Opin Neurol , vol.22 , pp. 524-531
    • Platt, D.1    Griggs, R.2
  • 3
    • 58149326824 scopus 로고    scopus 로고
    • Inherited neuronal ion channelopathies: New windows on complex neurological diseases
    • Catterall WA, Dib-Hajj S, Meisler MH and Pietrobon D: Inherited neuronal ion channelopathies: new windows on complex neurological diseases. J Neurosci 28: 11768-11777, 2008.
    • (2008) J Neurosci , vol.28 , pp. 11768-11777
    • Catterall, W.A.1    Dib-Hajj, S.2    Meisler, M.H.3    Pietrobon, D.4
  • 5
    • 79951932749 scopus 로고    scopus 로고
    • Ion channelopathies in endocrinology: Recent genetic fndings and pathophysiological insights
    • Rolim AL, Lindsey SC, Kunii IS, et al: Ion channelopathies in endocrinology: recent genetic fndings and pathophysiological insights. Arq bras Endocrinol metabol 54: 673-681, 2010.
    • (2010) Arq Bras Endocrinol Metabol , vol.54 , pp. 673-681
    • Rolim, A.L.1    Lindsey, S.C.2    Kunii, I.S.3
  • 6
    • 82455219496 scopus 로고    scopus 로고
    • Ion channels and transporters in cancer. 5. Ion channels in control of cancer and cell apoptosis
    • Lehen'kyi V, Shapovalov G, Skryma R and Prevarskaya N: Ion channels and transporters in cancer. 5. Ion channels in control of cancer and cell apoptosis. Am J Physiol Cell Physiol 301: C1281-C1289, 2011.
    • (2011) Am J Physiol Cell Physiol , vol.301 , pp. C1281-C1289
    • Lehen'Kyi, V.1    Shapovalov, G.2    Skryma, R.3    Prevarskaya, N.4
  • 7
    • 29144506662 scopus 로고    scopus 로고
    • Ion channels and cancer
    • Kunzelmann K: Ion channels and cancer. J membr biol 205: 159-173, 2005.
    • (2005) J Membr Biol , vol.205 , pp. 159-173
    • Kunzelmann, K.1
  • 8
    • 84893464588 scopus 로고    scopus 로고
    • Ion channels and transporters in the development of drug resistance in cancer cells
    • Hoffmann EK and Lambert IH: Ion channels and transporters in the development of drug resistance in cancer cells. Philos Trans R Soc Lond B Biol Sci 369: 20130109, 2014.
    • (2014) Philos Trans R Soc Lond B Biol Sci , vol.369 , pp. 20130109
    • Hoffmann, E.K.1    Lambert, I.H.2
  • 9
    • 84893463005 scopus 로고    scopus 로고
    • Ion channels in cancer: Future perspectives and clinical potential
    • Lang F and Stournaras C: Ion channels in cancer: future perspectives and clinical potential. Philos Trans R Soc Lond B Biol Sci 369: 20130108, 2014.
    • (2014) Philos Trans R Soc Lond B Biol Sci , vol.369 , pp. 20130108
    • Lang, F.1    Stournaras, C.2
  • 12
    • 34249274952 scopus 로고    scopus 로고
    • Targeting ion channels for new strategies in cancer diagnosis and therapy
    • Conti M: Targeting ion channels for new strategies in cancer diagnosis and therapy. Curr Clin Pharmacol 2: 135-144, 2007.
    • (2007) Curr Clin Pharmacol , vol.2 , pp. 135-144
    • Conti, M.1
  • 14
    • 84911476016 scopus 로고    scopus 로고
    • The role of ion channels and transporters in cell proliferation and cancer
    • Becchetti A, Munaron L and Arcangeli A: The role of ion channels and transporters in cell proliferation and cancer. Front Physiol 4: 312, 2013.
    • (2013) Front Physiol , vol.4 , pp. 312
    • Becchetti, A.1    Munaron, L.2    Arcangeli, A.3
  • 16
    • 29144508618 scopus 로고    scopus 로고
    • Ion channels in cell proliferation and apoptotic cell death
    • Lang F, Foller M, Lang KS, et al: Ion channels in cell proliferation and apoptotic cell death. J membr biol 205: 147-157, 2005.
    • (2005) J Membr Biol , vol.205 , pp. 147-157
    • Lang, F.1    Foller, M.2    Lang, K.S.3
  • 17
    • 35748976248 scopus 로고    scopus 로고
    • Cell volume regulatory ion channels in cell proliferation and cell death
    • Lang F, Foller M, Lang K, et al: Cell volume regulatory ion channels in cell proliferation and cell death. methods Enzymol 428: 209-225, 2007.
    • (2007) Methods Enzymol , vol.428 , pp. 209-225
    • Lang, F.1    Foller, M.2    Lang, K.3
  • 19
    • 70449718851 scopus 로고    scopus 로고
    • Bioelectric controls of cell proliferation: Ion channels, membrane voltage and the cell cycle
    • Blackiston DJ, McLaughlin KA and Levin M: Bioelectric controls of cell proliferation: ion channels, membrane voltage and the cell cycle. Cell Cycle 8: 3527-3536, 2009.
    • (2009) Cell Cycle , vol.8 , pp. 3527-3536
    • Blackiston, D.J.1    McLaughlin, K.A.2    Levin, M.3
  • 20
    • 0036883688 scopus 로고    scopus 로고
    • Expression and activity of potassium ion channels in human prostate cancer
    • Abdul M and Hoosein N: Expression and activity of potassium ion channels in human prostate cancer. Cancer Lett 186: 99-105, 2002.
    • (2002) Cancer Lett , vol.186 , pp. 99-105
    • Abdul, M.1    Hoosein, N.2
  • 22
    • 0037013256 scopus 로고    scopus 로고
    • A novel function of bCL-2 overexpression in regulatory volume decrease. Enhancing swelling-activated Ca(2+) entry and Cl(-) channel activity
    • Shen MR, Yang TP and Tang MJ: A novel function of bCL-2 overexpression in regulatory volume decrease. Enhancing swelling-activated Ca(2+) entry and Cl(-) channel activity. J biol Chem 277: 15592-15599, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 15592-15599
    • Shen, M.R.1    Yang, T.P.2    Tang, M.J.3
  • 23
    • 79958173184 scopus 로고    scopus 로고
    • The CLC-3 chloride channels in cardiovascular disease
    • Duan DD: The CLC-3 chloride channels in cardiovascular disease. Acta Pharmacol Sin 32: 675-684, 2011.
    • (2011) Acta Pharmacol Sin , vol.32 , pp. 675-684
    • Duan, D.D.1
  • 24
    • 41949119163 scopus 로고    scopus 로고
    • Suppression of CLC-3 channel expression reduces migration of nasopharyngeal carcinoma cells
    • Mao J, Chen L, Xu B, et al: Suppression of CLC-3 channel expression reduces migration of nasopharyngeal carcinoma cells. biochem Pharmacol 75: 1706-1716, 2008.
    • (2008) Biochem Pharmacol , vol.75 , pp. 1706-1716
    • Mao, J.1    Chen, L.2    Xu, B.3
  • 25
    • 3142767553 scopus 로고    scopus 로고
    • - current and CLC-3 expression in human prostate cancer epithelial cells
    • - current and CLC-3 expression in human prostate cancer epithelial cells. Cancer Res 64: 4841-4848, 2004.
    • (2004) Cancer Res , vol.64 , pp. 4841-4848
    • Lemonnier, L.1    Shuba, Y.2    Crepin, A.3
  • 26
    • 55249114962 scopus 로고    scopus 로고
    • CLC3 is a critical regulator of the cell cycle in normal and malignant glial cells
    • Habela CW, Olsen ML and Sontheimer H: CLC3 is a critical regulator of the cell cycle in normal and malignant glial cells. J Neurosci 28: 9205-9217, 2008.
    • (2008) J Neurosci , vol.28 , pp. 9205-9217
    • Habela, C.W.1    Olsen, M.L.2    Sontheimer, H.3
  • 27
    • 0141453864 scopus 로고    scopus 로고
    • Functional effects of novel anti-CLC-3 antibodies on native volume-sensitive osmolyte and anion channels in cardiac and smooth muscle cells
    • Wang GX, Hatton WJ, Wang GL, et al: Functional effects of novel anti-CLC-3 antibodies on native volume-sensitive osmolyte and anion channels in cardiac and smooth muscle cells. Am J Physiol heart Circ Physiol 285: h1453-h1463, 2003.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285 , pp. h1453-h1463
    • Wang, G.X.1    Hatton, W.J.2    Wang, G.L.3
  • 28
    • 16244370093 scopus 로고    scopus 로고
    • - currents by functional anti-CLC-3 antibody in native bovine non-pigmented ciliary epithelial cells
    • - currents by functional anti-CLC-3 antibody in native bovine non-pigmented ciliary epithelial cells. Invest Ophthalmol Vis Sci 46: 948-955, 2005.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 948-955
    • Do, C.W.1    Lu, W.2    Mitchell, C.H.3    Civan, M.M.4
  • 29
    • 14844290889 scopus 로고    scopus 로고
    • - concentration through volume-regulated CLC-3 chloride channels in A10 vascular smooth muscle cells
    • - concentration through volume-regulated CLC-3 chloride channels in A10 vascular smooth muscle cells. J biol Chem 280: 7301-7308, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 7301-7308
    • Zhou, J.G.1    Ren, J.L.2    Qiu, Q.Y.3    He, H.4    Guan, Y.Y.5
  • 31
    • 84879773470 scopus 로고    scopus 로고
    • CLC-3 is an intracellular chloride/proton exchanger with large voltage-dependent nonlinear capacitance
    • Guzman RE, Grieschat M, Fahlke C and Alekov AK: CLC-3 is an intracellular chloride/proton exchanger with large voltage-dependent nonlinear capacitance. ACS Chem Neurosci 4: 994-1003, 2013.
    • (2013) ACS Chem Neurosci , vol.4 , pp. 994-1003
    • Guzman, R.E.1    Grieschat, M.2    Fahlke, C.3    Alekov, A.K.4
  • 32
    • 22944479662 scopus 로고    scopus 로고
    • Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins
    • Scheel O, Zdebik AA, Lourdel S and Jentsch TJ: Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins. Nature 436: 424-427, 2005.
    • (2005) Nature , vol.436 , pp. 424-427
    • Scheel, O.1    Zdebik, A.A.2    Lourdel, S.3    Jentsch, T.J.4
  • 33
    • 22944475536 scopus 로고    scopus 로고
    • Chloride/proton antiporter activity of mammalian CLC proteins CLC-4 and CLC-5
    • Picollo A and Pusch M: Chloride/proton antiporter activity of mammalian CLC proteins CLC-4 and CLC-5. Nature 436: 420-423, 2005.
    • (2005) Nature , vol.436 , pp. 420-423
    • Picollo, A.1    Pusch, M.2
  • 34
  • 35
    • 0041968944 scopus 로고    scopus 로고
    • Subcellular localization and activity of multidrug resistance proteins
    • Rajagopal A and Simon SM: Subcellular localization and activity of multidrug resistance proteins. mol biol Cell 14: 3389-3399, 2003.
    • (2003) Mol Biol Cell , vol.14 , pp. 3389-3399
    • Rajagopal, A.1    Simon, S.M.2
  • 36
    • 34147092698 scopus 로고    scopus 로고
    • CLC-3 expression enhances etoposide resistance by increasing acidif-cation of the late endocytic compartment
    • Weylandt KH, Nebrig M, Jansen-Rosseck N, et al: CLC-3 expression enhances etoposide resistance by increasing acidif-cation of the late endocytic compartment. mol Cancer Ther 6: 979-986, 2007.
    • (2007) Mol Cancer Ther , vol.6 , pp. 979-986
    • Weylandt, K.H.1    Nebrig, M.2    Jansen-Rosseck, N.3
  • 37
    • 85006951047 scopus 로고    scopus 로고
    • Suppression of chloride channel 3 expression facilitates sensitivity of human glioma u251 cells to cisplatin through concomitant inhibition of Akt and autophagy
    • Su J, Xu Y, Zhou L, et al: Suppression of chloride channel 3 expression facilitates sensitivity of human glioma u251 cells to cisplatin through concomitant inhibition of Akt and autophagy. Anat Rec (hoboken) 296: 595-603, 2013.
    • (2013) Anat Rec (Hoboken) , vol.296 , pp. 595-603
    • Su, J.1    Xu, Y.2    Zhou, L.3
  • 38
    • 79956288024 scopus 로고    scopus 로고
    • 5-Nitro-2-(3-phenylpropylamino) benzoic acid induced drug resistance to cisplatin in human eryth-roleukemia cell lines
    • Xu Y, Zheng H, Kang JS, et al: 5-Nitro-2-(3-phenylpropylamino) benzoic acid induced drug resistance to cisplatin in human eryth-roleukemia cell lines. Anat Rec (hoboken). 294: 945-952, 2011.
    • (2011) Anat Rec (Hoboken). , vol.294 , pp. 945-952
    • Xu, Y.1    Zheng, H.2    Kang, J.S.3
  • 39
    • 77952959961 scopus 로고    scopus 로고
    • CLC-3 chloride channels are essential for cell proliferation and cell cycle progression in nasopharyngeal carcinoma cells
    • Xu B, Mao J, Wang L, et al: CLC-3 chloride channels are essential for cell proliferation and cell cycle progression in nasopharyngeal carcinoma cells. Acta biochim biophys Sin (Shanghai) 42: 370-380, 2010.
    • (2010) Acta Biochim Biophys Sin (Shanghai) , vol.42 , pp. 370-380
    • Xu, B.1    Mao, J.2    Wang, L.3
  • 40
    • 84873352274 scopus 로고    scopus 로고
    • The CLC-3 chloride channel protein is a downstream target of cyclin D1 in nasopharyngeal carcinoma cells
    • Zhang H, Zhu L, Zuo W, et al: The CLC-3 chloride channel protein is a downstream target of cyclin D1 in nasopharyngeal carcinoma cells. Int J biochem Cell biol 45: 672-683, 2013.
    • (2013) Int J Biochem Cell Biol , vol.45 , pp. 672-683
    • Zhang, H.1    Zhu, L.2    Zuo, W.3
  • 41
    • 47749110251 scopus 로고    scopus 로고
    • An unexpected role for ion channels in brain tumor metastasis
    • Sontheimer H: An unexpected role for ion channels in brain tumor metastasis. Exp biol med (maywood) 233: 779-791, 2008.
    • (2008) Exp Biol Med (Maywood) , vol.233 , pp. 779-791
    • Sontheimer, H.1
  • 42
    • 84863504002 scopus 로고    scopus 로고
    • CLC-3 is a candidate of the channel proteins mediating acid-activated chloride currents in nasopha-ryngeal carcinoma cells
    • Wang L, Ma W, Zhu L, et al: CLC-3 is a candidate of the channel proteins mediating acid-activated chloride currents in nasopha-ryngeal carcinoma cells. Am J Physiol Cell Physiol 303: C14-C23, 2012.
    • (2012) Am J Physiol Cell Physiol , vol.303 , pp. C14-C23
    • Wang, L.1    Ma, W.2    Zhu, L.3
  • 43
    • 84875043800 scopus 로고    scopus 로고
    • Effects of volume-activated chloride channels on the invasion and migration of human endometrial cancer cells
    • Li M, Wu DB and Wang J: Effects of volume-activated chloride channels on the invasion and migration of human endometrial cancer cells. Eur J Gynaecol Oncol 34: 60-64, 2013.
    • (2013) Eur J Gynaecol Oncol , vol.34 , pp. 60-64
    • Li, M.1    Wu, D.B.2    Wang, J.3
  • 44
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • Wen PY and Kesari S: Malignant gliomas in adults. N Engl J med 359: 492-507, 2008.
    • (2008) N Engl J Med , vol.359 , pp. 492-507
    • Wen, P.Y.1    Kesari, S.2
  • 45
    • 78650230042 scopus 로고    scopus 로고
    • Invasion of human glioma cells is regulated by multiple chloride channels including CLC-3
    • Lui VC, Lung SS, Pu JK, Hung KN and Leung GK: Invasion of human glioma cells is regulated by multiple chloride channels including CLC-3. Anticancer Res 30: 4515-4524, 2010.
    • (2010) Anticancer Res , vol.30 , pp. 4515-4524
    • Lui, V.C.1    Lung, S.S.2    Pu, J.K.3    Hung, K.N.4    Leung, G.K.5
  • 46
    • 0038383958 scopus 로고    scopus 로고
    • Expression of voltage-gated chloride channels in human glioma cells
    • Olsen ML, Schade S, Lyons SA, Amaral MD and Sontheimer H: Expression of voltage-gated chloride channels in human glioma cells. J Neurosci 23: 5572-5582, 2003.
    • (2003) J Neurosci , vol.23 , pp. 5572-5582
    • Olsen, M.L.1    Schade, S.2    Lyons, S.A.3    Amaral, M.D.4    Sontheimer, H.5
  • 48
    • 79955711577 scopus 로고    scopus 로고
    • Bradykinin promotes the chemotactic invasion of primary brain tumors
    • Montana V and Sontheimer H: Bradykinin promotes the chemotactic invasion of primary brain tumors. J Neurosci 31: 4858-4867, 2011.
    • (2011) J Neurosci , vol.31 , pp. 4858-4867
    • Montana, V.1    Sontheimer, H.2
  • 49
    • 77951220658 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase II (CamKII) in human malignant glioma
    • 2+/calmodulin-dependent protein kinase II (CamKII) in human malignant glioma. J Biol Chem 285: 11188-11196, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 11188-11196
    • Cuddapah, V.A.1    Sontheimer, H.2
  • 50
    • 0035827526 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase
    • 2+/calmodulin-dependent protein kinase. J Biol Chem 276: 20093-20100, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 20093-20100
    • Huang, P.1    Liu Di J, A.2
  • 51
    • 84872712836 scopus 로고    scopus 로고
    • Bradykinin-induced chemotaxis of human gliomas requires the activation of KCa3.1 and CLC-3
    • Cuddapah VA, Turner KL, Seifert S and Sontheimer H: Bradykinin-induced chemotaxis of human gliomas requires the activation of KCa3.1 and CLC-3. J Neurosci 33: 1427-1440, 2013.
    • (2013) J Neurosci , vol.33 , pp. 1427-1440
    • Cuddapah, V.A.1    Turner, K.L.2    Seifert, S.3    Sontheimer, H.4
  • 52
    • 34548258859 scopus 로고    scopus 로고
    • Cytoplasmic volume condensation is an integral part of mitosis
    • Habela CW and Sontheimer H: Cytoplasmic volume condensation is an integral part of mitosis. Cell Cycle 6: 1613-1620, 2007.
    • (2007) Cell Cycle , vol.6 , pp. 1613-1620
    • Habela, C.W.1    Sontheimer, H.2
  • 54
    • 3142681237 scopus 로고    scopus 로고
    • CLC-3 expression in the cell cycle of nasopharyngeal carcinoma cells
    • Wang LW, Chen LX and Jacob T: CLC-3 expression in the cell cycle of nasopharyngeal carcinoma cells. Sheng Li Xue bao 56: 230-236, 2004.
    • (2004) Sheng Li Xue Bao , vol.56 , pp. 230-236
    • Wang, L.W.1    Chen, L.X.2    Jacob, T.3
  • 55
    • 84862833314 scopus 로고    scopus 로고
    • CLC-3 siRNA inhibits regulatory volume decrease in nasopharyngeal carcinoma cells
    • (In Chinese)
    • Ye D, Zhang HF, Zhu LY, Wang LW and Chen LX: CLC-3 siRNA inhibits regulatory volume decrease in nasopharyngeal carcinoma cells. Nan Fang Yi Ke Da Xue Xue bao 31: 216-220, 2011 (In Chinese).
    • (2011) Nan Fang Yi Ke da Xue Xue Bao , vol.31 , pp. 216-220
    • Ye, D.1    Zhang, H.F.2    Zhu, L.Y.3    Wang, L.W.4    Chen, L.X.5
  • 56
    • 79960696366 scopus 로고    scopus 로고
    • CLC-3 is A main component of background chloride channels activated under isotonic conditions by autocrine ATP in nasopharyngeal varcinoma cells
    • Yang L, Ye D, Ye W, et al: CLC-3 Is A main component of background chloride channels activated under isotonic conditions by autocrine ATP in nasopharyngeal varcinoma cells. J Cell Physiol 226: 2516-2526, 2011.
    • (2011) J Cell Physiol , vol.226 , pp. 2516-2526
    • Yang, L.1    Ye, D.2    Ye, W.3
  • 57
    • 84455205503 scopus 로고    scopus 로고
    • Differential expression and roles of volume-activated chloride channels in control of growth of normal and cancerous nasopharyngeal epithelial cells
    • Zhu L, Yang H, Zuo W, et al: Differential expression and roles of volume-activated chloride channels in control of growth of normal and cancerous nasopharyngeal epithelial cells. biochem Pharmacol 83: 324-334, 2012.
    • (2012) Biochem Pharmacol , vol.83 , pp. 324-334
    • Zhu, L.1    Yang, H.2    Zuo, W.3
  • 58
    • 0345389967 scopus 로고    scopus 로고
    • Ph and drug resistance. II. Turnover of acidic vesicles and resistance to weakly basic chemotherapeutic drugs
    • Raghunand N, Martinez-Zaguilan R, Wright SH and Gillies RJ: ph and drug resistance. II. Turnover of acidic vesicles and resistance to weakly basic chemotherapeutic drugs. biochem Pharmacol 57: 1047-1058, 1999.
    • (1999) Biochem Pharmacol , vol.57 , pp. 1047-1058
    • Raghunand, N.1    Martinez-Zaguilan, R.2    Wright, S.H.3    Gillies, R.J.4
  • 59
    • 55949107533 scopus 로고    scopus 로고
    • Physiology of cell volume regulation in vertebrates
    • Hoffmann EK, Lambert IH and Pedersen SF: Physiology of cell volume regulation in vertebrates. Physiol Rev 89: 193-277, 2009.
    • (2009) Physiol Rev , vol.89 , pp. 193-277
    • Hoffmann, E.K.1    Lambert, I.H.2    Pedersen, S.F.3
  • 60
    • 34848884233 scopus 로고    scopus 로고
    • Mechanisms and signifcance of cell volume regulation
    • Lang F: Mechanisms and signifcance of cell volume regulation. J Am Coll Nutr 26: S613-S623, 2007.
    • (2007) J Am Coll Nutr , vol.26 , pp. S613-S623
    • Lang, F.1
  • 62
    • 0035336894 scopus 로고    scopus 로고
    • Blocking swelling-activated chloride current inhibits mouse liver cell proliferation
    • Wondergem R, Gong W, Monen SH, et al: Blocking swelling-activated chloride current inhibits mouse liver cell proliferation. J Physiol 532: 661-672, 2001.
    • (2001) J Physiol , vol.532 , pp. 661-672
    • Wondergem, R.1    Gong, W.2    Monen, S.H.3
  • 64
    • 84892979752 scopus 로고    scopus 로고
    • - currents and intracellular CLC-3 are involved in proliferation of human pulmonary artery smooth muscle cells
    • - currents and intracellular CLC-3 are involved in proliferation of human pulmonary artery smooth muscle cells. J hypertens 32: 318-330, 2014.
    • (2014) J Hypertens , vol.32 , pp. 318-330
    • Liang, W.1    Huang, L.2    Zhao, D.3
  • 65
    • 0034525163 scopus 로고    scopus 로고
    • Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells
    • Shen MR, Droogmans G, Eggermont J, Voets T, Ellory JC and Nilius B: Differential expression of volume-regulated anion channels during cell cycle progression of human cervical cancer cells. J Physiol 529: 385-394, 2000.
    • (2000) J Physiol , vol.529 , pp. 385-394
    • Shen, M.R.1    Droogmans, G.2    Eggermont, J.3    Voets, T.4    Ellory, J.C.5    Nilius, B.6
  • 66
    • 0031456376 scopus 로고    scopus 로고
    • Molecular identifcation of a volume-regulated chloride channel
    • Duan D, Winter C, Cowley S, Hume JR and Horowitz B: Molecular identifcation of a volume-regulated chloride channel. Nature 390: 417-421, 1997.
    • (1997) Nature , vol.390 , pp. 417-421
    • Duan, D.1    Winter, C.2    Cowley, S.3    Hume, J.R.4    Horowitz, B.5
  • 69
    • 73049083160 scopus 로고    scopus 로고
    • Cardiac-specifc, inducible CLC-3 gene deletion eliminates native volume-sensitive chloride channels and produces myocardial hypertrophy in adult mice
    • Xiong D, Heyman NS, Airey J, et al: Cardiac-specifc, inducible CLC-3 gene deletion eliminates native volume-sensitive chloride channels and produces myocardial hypertrophy in adult mice. J Mol Cell Cardiol 48: 211-219, 2010.
    • (2010) J Mol Cell Cardiol , vol.48 , pp. 211-219
    • Xiong, D.1    Heyman, N.S.2    Airey, J.3
  • 70
    • 0037110802 scopus 로고    scopus 로고
    • Defciency in CLC-3 chloride channels prevents rat aortic smooth muscle cell proliferation
    • Wang GL, Wang XR, Lin MJ, He H, Lan XJ and Guan YY: Defciency in CLC-3 chloride channels prevents rat aortic smooth muscle cell proliferation. Circ Res 91: E28-E32, 2002.
    • (2002) Circ Res , vol.91 , pp. E28-E32
    • Wang, G.L.1    Wang, X.R.2    Lin, M.J.3    He, H.4    Lan, X.J.5    Guan, Y.Y.6
  • 71
    • 51649095700 scopus 로고    scopus 로고
    • Silence of CLC-3 chloride channel inhibits cell proliferation and the cell cycle via G/S phase arrest in rat basilar arterial smooth muscle cells
    • Tang YB, Liu YJ, Zhou JG, Wang GL, Qiu QY and Guan YY: Silence of CLC-3 chloride channel inhibits cell proliferation and the cell cycle via G/S phase arrest in rat basilar arterial smooth muscle cells. Cell Prolif 41: 775-785, 2008.
    • (2008) Cell Prolif , vol.41 , pp. 775-785
    • Tang, Y.B.1    Liu, Y.J.2    Zhou, J.G.3    Wang, G.L.4    Qiu, Q.Y.5    Guan, Y.Y.6
  • 72
    • 14744271069 scopus 로고    scopus 로고
    • Cell size-dependent and independent proliferation of rodent neuro-blastoma x glioma cells
    • Rouzaire-Dubois B, O'Regan S and Dubois JM: Cell size-dependent and independent proliferation of rodent neuro-blastoma x glioma cells. J Cell Physiol 203: 243-250, 2005.
    • (2005) J Cell Physiol , vol.203 , pp. 243-250
    • Rouzaire-Dubois, B.1    O'Regan, S.2    Dubois, J.M.3
  • 73
    • 4344671278 scopus 로고    scopus 로고
    • The infuence of cell volume changes on tumour cell proliferation
    • Dubois JM and Rouzaire-Dubois B: The infuence of cell volume changes on tumour cell proliferation. Eur biophys J 33: 227-232, 2004.
    • (2004) Eur Biophys J , vol.33 , pp. 227-232
    • Dubois, J.M.1    Rouzaire-Dubois, B.2
  • 74
    • 0033230627 scopus 로고    scopus 로고
    • Osmotic cell swelling-induced ATP release mediates the activation of extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels
    • Van der wijk T, De Jonge HR and Tilly BC: Osmotic cell swelling-induced ATP release mediates the activation of extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels. Biochem J 343: 579-586, 1999.
    • (1999) Biochem J , vol.343 , pp. 579-586
    • Van Der Wijk, T.1    De Jonge, H.R.2    Tilly, B.C.3
  • 75
    • 10544232283 scopus 로고    scopus 로고
    • Tyrosine kinase activation is an immediate and essential step in hypotonic cell swelling-induced ERK activation and c-fos gene expression in cardiac myocytes
    • Sadoshima J, Qiu Z, Morgan JP and Izumo S: Tyrosine kinase activation is an immediate and essential step in hypotonic cell swelling-induced ERK activation and c-fos gene expression in cardiac myocytes. EmbO J 15: 5535-5546, 1996.
    • (1996) EmbO J , vol.15 , pp. 5535-5546
    • Sadoshima, J.1    Qiu, Z.2    Morgan, J.P.3    Izumo, S.4
  • 76
    • 84866385935 scopus 로고    scopus 로고
    • Interplay between mEK-ERK signaling, cyclin D1 and cyclin-dependent kinase 5 regulates cell cycle reentry and apoptosis of neurons
    • Modi PK, Komaravelli N, Singh N and Sharma P: Interplay between mEK-ERK signaling, cyclin D1 and cyclin-dependent kinase 5 regulates cell cycle reentry and apoptosis of neurons. Mol Biol Cell 23: 3722-3730, 2012.
    • (2012) Mol Biol Cell , vol.23 , pp. 3722-3730
    • Modi, P.K.1    Komaravelli, N.2    Singh, N.3    Sharma, P.4
  • 77
    • 84155175868 scopus 로고    scopus 로고
    • ERK crosstalks with 4EbP1 to activate cyclin D1 translation during quinol-thioether-induced tuberous sclerosis renal cell carcinoma
    • Cohen JD, Gard JM, Nagle RB, Dietrich JD, Monks TJ and Lau SS: ERK crosstalks with 4EbP1 to activate cyclin D1 translation during quinol-thioether-induced tuberous sclerosis renal cell carcinoma. Toxicol Sci 124: 75-87, 2011.
    • (2011) Toxicol Sci , vol.124 , pp. 75-87
    • Cohen, J.D.1    Gard, J.M.2    Nagle, R.B.3    Dietrich, J.D.4    Monks, T.J.5    Lau, S.S.6
  • 78
    • 0033821840 scopus 로고    scopus 로고
    • The importance of ERK activity in the regulation of cyclin D1 levels and DNA synthesis in human cultured airway smooth muscle
    • Ravenhall C, Guida E, Harris T, Koutsoubos V and Stewart A: The importance of ERK activity in the regulation of cyclin D1 levels and DNA synthesis in human cultured airway smooth muscle. Br J Pharmacol 131: 17-28, 2000.
    • (2000) Br J Pharmacol , vol.131 , pp. 17-28
    • Ravenhall, C.1    Guida, E.2    Harris, T.3    Koutsoubos, V.4    Stewart, A.5
  • 80
    • 0035752583 scopus 로고    scopus 로고
    • Cellular function and control of volume-regulated anion channels
    • Eggermont J, Trouet D, Carton I and Nilius B: Cellular function and control of volume-regulated anion channels. Cell Biochem biophys 35: 263-274, 2001.
    • (2001) Cell Biochem Biophys , vol.35 , pp. 263-274
    • Eggermont, J.1    Trouet, D.2    Carton, I.3    Nilius, B.4
  • 81
    • 84891713908 scopus 로고    scopus 로고
    • Cell volume regulation in epithelial physiology and cancer
    • Pedersen SF, Hoffmann EK and Novak I: Cell volume regulation in epithelial physiology and cancer. Front Physiol 4: 233, 2013.
    • (2013) Front Physiol , vol.4 , pp. 233
    • Pedersen, S.F.1    Hoffmann, E.K.2    Novak, I.3
  • 82
    • 33744791766 scopus 로고    scopus 로고
    • Swelling-activated ion channels: Functional regulation in cell-swelling, proliferation and apoptosis
    • Stutzin A and Hoffmann EK: Swelling-activated ion channels: functional regulation in cell-swelling, proliferation and apoptosis. Acta Physiol (Oxf) 187: 27-42, 2006.
    • (2006) Acta Physiol (Oxf) , vol.187 , pp. 27-42
    • Stutzin, A.1    Hoffmann, E.K.2
  • 83
    • 0034662989 scopus 로고    scopus 로고
    • Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis
    • Maeno E, Ishizaki Y, Kanaseki T, Hazama A and Okada Y: Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis. Proc Natl Acad Sci uSA 97: 9487-9492, 2000.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 9487-9492
    • Maeno, E.1    Ishizaki, Y.2    Kanaseki, T.3    Hazama, A.4    Okada, Y.5
  • 84
    • 33646586354 scopus 로고    scopus 로고
    • Volume-sensitive chloride channels involved in apoptotic volume decrease and cell death
    • Okada Y, Shimizu T, Maeno E, Tanabe S, Wang X and Takahashi N: Volume-sensitive chloride channels involved in apoptotic volume decrease and cell death. J membr biol 209: 21-29, 2006.
    • (2006) J Membr Biol , vol.209 , pp. 21-29
    • Okada, Y.1    Shimizu, T.2    Maeno, E.3    Tanabe, S.4    Wang, X.5    Takahashi, N.6
  • 85
    • 79955788115 scopus 로고    scopus 로고
    • CLC-3 chloride channel prevents apoptosis induced by hydrogen peroxide in basilar artery smooth muscle cells through mitochondria dependent pathway
    • Qian Y, Du YH, Tang YB, et al: CLC-3 chloride channel prevents apoptosis induced by hydrogen peroxide in basilar artery smooth muscle cells through mitochondria dependent pathway. Apoptosis 16: 468-477, 2011.
    • (2011) Apoptosis , vol.16 , pp. 468-477
    • Qian, Y.1    Du, Y.H.2    Tang, Y.B.3
  • 86
    • 36348982335 scopus 로고    scopus 로고
    • Involvement of chloride channels in TGF-beta1-induced apoptosis of human bronchial epithelial cells
    • Cheng G, Shao Z, Chaudhari B and Agrawal DK: Involvement of chloride channels in TGF-beta1-induced apoptosis of human bronchial epithelial cells. Am J Physiol Lung Cell mol Physiol 293: L1339-1347, 2007.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293 , pp. L1339-1347
    • Cheng, G.1    Shao, Z.2    Chaudhari, B.3    Agrawal, D.K.4
  • 87
    • 33645236273 scopus 로고    scopus 로고
    • CLC-3 chloride channel prevents apoptosis induced by thapsigargin in PC12 cells
    • Zhang HN, Zhou JG, Qiu QY, Ren JL and Guan YY: CLC-3 chloride channel prevents apoptosis induced by thapsigargin in PC12 cells. Apoptosis 11: 327-336, 2006.
    • (2006) Apoptosis , vol.11 , pp. 327-336
    • Zhang, H.N.1    Zhou, J.G.2    Qiu, Q.Y.3    Ren, J.L.4    Guan, Y.Y.5
  • 88
    • 84893661246 scopus 로고    scopus 로고
    • The CLC-3 chloride channel associated with microtubules is a target of paclitaxel in its induced-apoptosis
    • Zhang H, Li H, Yang L, et al: The CLC-3 chloride channel associated with microtubules is a target of paclitaxel in its induced-apoptosis. Sci Rep 3: 2615, 2013.
    • (2013) Sci Rep , vol.3 , pp. 2615
    • Zhang, H.1    Li, H.2    Yang, L.3
  • 89
    • 84880854376 scopus 로고    scopus 로고
    • Discovery of bufadienolides as a novel class of CLC-3 chloride channel activators with antitumor activities
    • Liu J, Zhang D, Li Y, et al: Discovery of bufadienolides as a novel class of CLC-3 chloride channel activators with antitumor activities. J Med Chem 56: 5734-5743, 2013.
    • (2013) J Med Chem , vol.56 , pp. 5734-5743
    • Liu, J.1    Zhang, D.2    Li, Y.3
  • 90
    • 34250816328 scopus 로고    scopus 로고
    • Up-regulation of bcl-2 is required for the progression of prostate cancer cells from an androgen-dependent to an androgen-independent growth stage
    • Lin Y, Fukuchi J, Hiipakka RA, Kokontis JM and Xiang J: up-regulation of bcl-2 is required for the progression of prostate cancer cells from an androgen-dependent to an androgen-independent growth stage. Cell Res 17: 531-536, 2007.
    • (2007) Cell Res , vol.17 , pp. 531-536
    • Lin, Y.1    Fukuchi, J.2    Hiipakka, R.A.3    Kokontis, J.M.4    Xiang, J.5
  • 91
    • 55249091085 scopus 로고    scopus 로고
    • TmEm16A confers receptor-activated calcium-dependent chloride conductance
    • Yang YD, Cho H, Koo JY, et al: TmEm16A confers receptor-activated calcium-dependent chloride conductance. Nature 455: 1210-1215, 2008.
    • (2008) Nature , vol.455 , pp. 1210-1215
    • Yang, Y.D.1    Cho, H.2    Koo, J.Y.3
  • 93
    • 34547636154 scopus 로고    scopus 로고
    • Monoclonal antibody blockade of the human Eag1 potassium channel function exerts antitumor activity
    • Gomez-Varela D, Zwick-Wallasch E, Knotgen H, et al: Monoclonal antibody blockade of the human Eag1 potassium channel function exerts antitumor activity. Cancer Res 67: 7343-7349, 2007.
    • (2007) Cancer Res , vol.67 , pp. 7343-7349
    • Gomez-Varela, D.1    Zwick-Wallasch, E.2    Knotgen, H.3
  • 94
    • 0026045413 scopus 로고
    • Chloride channel inhibition by the venom of the scorpion Leiurus quinquestriatus
    • Debin JA and Strichartz GR: Chloride channel inhibition by the venom of the scorpion Leiurus quinquestriatus. Toxicon 29: 1403-1408, 1991.
    • (1991) Toxicon , vol.29 , pp. 1403-1408
    • Debin, J.A.1    Strichartz, G.R.2
  • 95
    • 0037423212 scopus 로고    scopus 로고
    • Chlorotoxin inhibits glioma cell invasion via matrix metalloproteinase-2
    • Deshane J, Garner CC and Sontheimer H: Chlorotoxin inhibits glioma cell invasion via matrix metalloproteinase-2. J Biol Chem 278: 4135-4144, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 4135-4144
    • Deshane, J.1    Garner, C.C.2    Sontheimer, H.3
  • 96
    • 84899963788 scopus 로고    scopus 로고
    • The impact of a chlorotoxin-modifed liposome system on receptor mmP-2 and the receptor-associated protein CLC-3
    • Qin C, He B, Dai W, et al: The impact of a chlorotoxin-modifed liposome system on receptor mmP-2 and the receptor-associated protein CLC-3. Biomaterials 35: 5908-5920, 2014.
    • (2014) Biomaterials , vol.35 , pp. 5908-5920
    • Qin, C.1    He, B.2    Dai, W.3
  • 97
    • 33747059059 scopus 로고    scopus 로고
    • Phase i single-dose study of intracavitary-administered iodine-131-Tm-601 in adults with recurrent high-grade glioma
    • Mamelak AN, Rosenfeld S, Bucholz R, et al: Phase I single-dose study of intracavitary-administered iodine-131-Tm-601 in adults with recurrent high-grade glioma. J Clin Oncol 24: 3644-3650, 2006.
    • (2006) J Clin Oncol , vol.24 , pp. 3644-3650
    • Mamelak, A.N.1    Rosenfeld, S.2    Bucholz, R.3
  • 98
    • 40849124038 scopus 로고    scopus 로고
    • Cardiac glycosides as novel cancer therapeutic agents
    • Newman RA, Yang P, Pawlus AD and Block KI: Cardiac glycosides as novel cancer therapeutic agents. Mol Interv 8: 36-49, 2008.
    • (2008) Mol Interv , vol.8 , pp. 36-49
    • Newman, R.A.1    Yang, P.2    Pawlus, A.D.3    Block, K.I.4
  • 99
    • 76549121007 scopus 로고    scopus 로고
    • In vitro cardio-toxicity and mechanism of action of the Egyptian green toad Bufo viridis skin secretions
    • Abdel-Rahman MA, Ahmed SH and Nabil ZI: In vitro cardio-toxicity and mechanism of action of the Egyptian green toad Bufo viridis skin secretions. Toxicol In Vitro 24: 480-485, 2010.
    • (2010) Toxicol in Vitro , vol.24 , pp. 480-485
    • Abdel-Rahman, M.A.1    Ahmed, S.H.2    Nabil, Z.I.3
  • 100
    • 38449123299 scopus 로고    scopus 로고
    • Cardioactive steroid poisoning: A comparison of plant-and animal-derived compounds
    • Barrueto F JR, Kirrane BM, Cotter BW, Hoffman RS and Nelson LS: Cardioactive steroid poisoning: a comparison of plant-and animal-derived compounds. J Med Toxicol 2: 152-155, 2006.
    • (2006) J Med Toxicol , vol.2 , pp. 152-155
    • Barrueto, F.1    Kirrane, B.M.2    Cotter, B.W.3    Hoffman, R.S.4    Nelson, L.S.5
  • 101
    • 80755125538 scopus 로고    scopus 로고
    • Improved antitumor effcacy and reduced toxicity of liposomes containing bufadi-enolides
    • Hu K, Zhu L, Liang H, Hu F and Feng J: Improved antitumor effcacy and reduced toxicity of liposomes containing bufadi-enolides. Arch Pharm Res 34: 1487-1494, 2011.
    • (2011) Arch Pharm Res , vol.34 , pp. 1487-1494
    • Hu, K.1    Zhu, L.2    Liang, H.3    Hu, F.4    Feng, J.5
  • 102
    • 0035998271 scopus 로고    scopus 로고
    • CLC-3 defciency leads to phenotypes similar to human neuronal ceroid lipofuscinosis
    • Yoshikawa M, Uchida S, Ezaki J, et al: CLC-3 defciency leads to phenotypes similar to human neuronal ceroid lipofuscinosis. Genes Cells 7: 597-605, 2002.
    • (2002) Genes Cells , vol.7 , pp. 597-605
    • Yoshikawa, M.1    Uchida, S.2    Ezaki, J.3


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