Swelling-activated Cl- currents and intracellular CLC-3 are involved in proliferation of human pulmonary artery smooth muscle cells

Journal of Hypertension

Volumn 32, Issue 2, 2014, Pages 318-330

  Liang, Wenbin ^a,e,f   Huang, Lihong ^a,b   Zhao, Dongling ^a   He, Jeff Z ^c,d   Sharma, Parveen ^a   Liu, Jie ^a   Gramolini, Anthony O ^a   Ward, Michael E ^c,d   Cho, Hee Cheol ^e   Backx, Peter H ^a,f  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b JILIN UNIVERSITY   (China)

^c ST MICHAEL'S HOSPITAL   (Canada)

^d ST MICHAEL'S HOSPITAL   (Canada)

^e CEDARS SINAI MEDICAL CENTER   (United States)

^f UNIVERSITY OF TORONTO   (Canada)

Author keywords

3 dihydro 1 oxo 1H inden 5 yl)oxy butanoic acid; 4 (2 Butyl 6; 7 dichloro 2 cyclopentyl 2; CLC 3; proliferation; pulmonary arterial hypertension; RNAi

Indexed keywords

4 [(2 BUTYL 6,7 DICHLORO 2 CYCLOPENTYL 2,3 DIHYDRO 1 OXO 1H INDEN 5 YL)OXY]BUTANOIC ACID; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; BESTROPHIN 1; BESTROPHIN 2; BESTROPHIN 3; BESTROPHIN 4; CHLORIDE CHANNEL; CHLORIDE CHANNEL 1; CHLORIDE CHANNEL 2; CHLORIDE CHANNEL 3; CHLORIDE CHANNEL 4; CHLORIDE CHANNEL 5; CHLORIDE CHANNEL 6; CHLORIDE CHANNEL 7; CHLORIDE CHANNEL BLOCKING AGENT; CHLORIDE CHANNEL KA; CHLORIDE CHANNEL KB; MEMBRANE PROTEIN; MESSENGER RNA; MICRORNA; RNA 28S; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL COUNT; CELL CULTURE; CELL PROLIFERATION; CELL SWELLING; CELLULAR DISTRIBUTION; CHLORIDE CURRENT; CONTROLLED STUDY; EXON; GENE SILENCING; HUMAN; HUMAN CELL; IC 50; LENTIVIRINAE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARCOLEMMA; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; STABLE EXPRESSION; UPREGULATION; WHOLE CELL PATCH CLAMP;

4,4'-DIISOTHIOCYANOSTILBENE-2,2'-DISULFONIC ACID; ANIMALS; CELL ENLARGEMENT; CELL PROLIFERATION; CELLS, CULTURED; CHLORIDE CHANNELS; CHLORIDES; CYCLOPENTANES; GENE KNOCKDOWN TECHNIQUES; HUMANS; HYPERTENSION, PULMONARY; IMMUNOHISTOCHEMISTRY; INDANS; MYOCYTES, SMOOTH MUSCLE; PATCH-CLAMP TECHNIQUES; PULMONARY ARTERY; RATS; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 84892979752     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0000000000000013     Document Type: Article

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