메뉴 건너뛰기




Volumn 356, Issue 2, 2015, Pages 347-356

Adeno-associated virus-mediated cancer gene therapy: Current status

Author keywords

Adeno associated virus; Cancer; Cancer gene therapy; Gene vehicle

Indexed keywords

BETA INTERFERON; BLOOD CLOTTING FACTOR 9; CHEMOKINE RECEPTOR CCR4; INTERLEUKIN 12; INTERLEUKIN 15; MICRORNA; PARVOVIRUS VECTOR; PROGRAMMED DEATH 1 RECEPTOR; PROSTATE SPECIFIC ANTIGEN; PROTEINASE ACTIVATED RECEPTOR 4;

EID: 84919430043     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.10.045     Document Type: Review
Times cited : (64)

References (122)
  • 2
    • 84896932506 scopus 로고    scopus 로고
    • Overcoming drug resistance in ALK-rearranged lung cancer
    • Thomas R.K. Overcoming drug resistance in ALK-rearranged lung cancer. N. Engl. J. Med 2014, 370:1250-1251.
    • (2014) N. Engl. J. Med , vol.370 , pp. 1250-1251
    • Thomas, R.K.1
  • 3
    • 84866418981 scopus 로고    scopus 로고
    • Nonviral gene therapy targeting cardiovascular system
    • Su C.H., Wu Y.J., Wang H.H., Yeh H.I. Nonviral gene therapy targeting cardiovascular system. Am. J. Physiol 2012, 303:H629-H638.
    • (2012) Am. J. Physiol , vol.303 , pp. H629-H638
    • Su, C.H.1    Wu, Y.J.2    Wang, H.H.3    Yeh, H.I.4
  • 4
    • 84890755202 scopus 로고    scopus 로고
    • Advances in recombinant adeno-associated viral vectors for gene delivery
    • Petrs-Silva H., Linden R. Advances in recombinant adeno-associated viral vectors for gene delivery. Curr. Gene Ther 2013, 13:335-345.
    • (2013) Curr. Gene Ther , vol.13 , pp. 335-345
    • Petrs-Silva, H.1    Linden, R.2
  • 5
    • 0001592496 scopus 로고
    • Adenovirus-associated defective virus particles
    • Atchison R.W., Casto B.C., Hammon W.M. Adenovirus-associated defective virus particles. Science 1965, 149:754-756.
    • (1965) Science , vol.149 , pp. 754-756
    • Atchison, R.W.1    Casto, B.C.2    Hammon, W.M.3
  • 6
    • 0031984786 scopus 로고    scopus 로고
    • Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2
    • Rutledge E.A., Halbert C.L., Russell D.W. Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2. J. Virol 1998, 72:309-319.
    • (1998) J. Virol , vol.72 , pp. 309-319
    • Rutledge, E.A.1    Halbert, C.L.2    Russell, D.W.3
  • 7
    • 0036678455 scopus 로고    scopus 로고
    • The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy
    • Xie Q., Bu W., Bhatia S., Hare J., Somasundaram T., Azzi A., et al. The atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:10405-10410.
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 10405-10410
    • Xie, Q.1    Bu, W.2    Bhatia, S.3    Hare, J.4    Somasundaram, T.5    Azzi, A.6
  • 8
    • 2642512201 scopus 로고    scopus 로고
    • Clades of adeno-associated viruses are widely disseminated in human tissues
    • Gao G., Vandenberghe L.H., Alvira M.R., Lu Y., Calcedo R., Zhou X., et al. Clades of adeno-associated viruses are widely disseminated in human tissues. J. Virol 2004, 78:6381-6388.
    • (2004) J. Virol , vol.78 , pp. 6381-6388
    • Gao, G.1    Vandenberghe, L.H.2    Alvira, M.R.3    Lu, Y.4    Calcedo, R.5    Zhou, X.6
  • 9
    • 0037320191 scopus 로고    scopus 로고
    • Characterization of tissue tropism determinants of adeno-associated virus type 1
    • Hauck B., Xiao W. Characterization of tissue tropism determinants of adeno-associated virus type 1. J. Virol 2003, 77:2768-2774.
    • (2003) J. Virol , vol.77 , pp. 2768-2774
    • Hauck, B.1    Xiao, W.2
  • 10
    • 84905456909 scopus 로고    scopus 로고
    • Systemic administration of a recombinant AAV1 vector encoding IGF-1 improves disease manifestations in SMA mice
    • Tsai L.K., Chen C.L., Ting C.H., Lin-Chao S., Hwu W.L., Dodge J.C., et al. Systemic administration of a recombinant AAV1 vector encoding IGF-1 improves disease manifestations in SMA mice. Mol. Ther 2014, 22:1450-1459.
    • (2014) Mol. Ther , vol.22 , pp. 1450-1459
    • Tsai, L.K.1    Chen, C.L.2    Ting, C.H.3    Lin-Chao, S.4    Hwu, W.L.5    Dodge, J.C.6
  • 11
    • 84902476451 scopus 로고    scopus 로고
    • The influence of AAV2-mediated gene transfer of human IL-10 on neurodegeneration and immune response in a murine model of Parkinson's disease
    • Joniec-Maciejak I., Ciesielska A., Wawer A., Sznejder-Pacholek A., Schwenkgrub J., Cudna A., et al. The influence of AAV2-mediated gene transfer of human IL-10 on neurodegeneration and immune response in a murine model of Parkinson's disease. Pharmacol. Rep 2014, 66:660-669.
    • (2014) Pharmacol. Rep , vol.66 , pp. 660-669
    • Joniec-Maciejak, I.1    Ciesielska, A.2    Wawer, A.3    Sznejder-Pacholek, A.4    Schwenkgrub, J.5    Cudna, A.6
  • 13
    • 84896328104 scopus 로고    scopus 로고
    • Subretinal delivery of AAV2-mediated human erythropoietin gene is protective and safe in experimental diabetic retinopathy
    • Xu H., Zhang L., Gu L., Lu L., Gao G., Li W., et al. Subretinal delivery of AAV2-mediated human erythropoietin gene is protective and safe in experimental diabetic retinopathy. Invest. Ophthalmol. Vis. Sci 2014, 55:1519-1530.
    • (2014) Invest. Ophthalmol. Vis. Sci , vol.55 , pp. 1519-1530
    • Xu, H.1    Zhang, L.2    Gu, L.3    Lu, L.4    Gao, G.5    Li, W.6
  • 14
    • 25144438473 scopus 로고    scopus 로고
    • Specific and efficient transduction of cochlear inner hair cells with recombinant adeno-associated virus type 3 vector
    • Liu Y., Okada T., Sheykholeslami K., Shimazaki K., Nomoto T., Muramatsu S., et al. Specific and efficient transduction of cochlear inner hair cells with recombinant adeno-associated virus type 3 vector. Mol. Ther 2005, 12:725-733.
    • (2005) Mol. Ther , vol.12 , pp. 725-733
    • Liu, Y.1    Okada, T.2    Sheykholeslami, K.3    Shimazaki, K.4    Nomoto, T.5    Muramatsu, S.6
  • 15
    • 70349748434 scopus 로고    scopus 로고
    • AAV3-mediated transfer and expression of the pyruvate dehydrogenase E1 alpha subunit gene causes metabolic remodeling and apoptosis of human liver cancer cells
    • Glushakova L.G., Lisankie M.J., Eruslanov E.B., Ojano-Dirain C., Zolotukhin I., Liu C., et al. AAV3-mediated transfer and expression of the pyruvate dehydrogenase E1 alpha subunit gene causes metabolic remodeling and apoptosis of human liver cancer cells. Mol. Genet. Metab 2009, 98:289-299.
    • (2009) Mol. Genet. Metab , vol.98 , pp. 289-299
    • Glushakova, L.G.1    Lisankie, M.J.2    Eruslanov, E.B.3    Ojano-Dirain, C.4    Zolotukhin, I.5    Liu, C.6
  • 16
    • 84888031467 scopus 로고    scopus 로고
    • Multiple roles for sialylated glycans in determining the cardiopulmonary tropism of adeno-associated virus 4
    • Shen S., Troupes A.N., Pulicherla N., Asokan A. Multiple roles for sialylated glycans in determining the cardiopulmonary tropism of adeno-associated virus 4. J. Virol 2013, 87:13206-13213.
    • (2013) J. Virol , vol.87 , pp. 13206-13213
    • Shen, S.1    Troupes, A.N.2    Pulicherla, N.3    Asokan, A.4
  • 17
    • 0034026085 scopus 로고    scopus 로고
    • Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer
    • Zabner J., Seiler M., Walters R., Kotin R.M., Fulgeras W., Davidson B.L., et al. Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer. J. Virol 2000, 74:3852-3858.
    • (2000) J. Virol , vol.74 , pp. 3852-3858
    • Zabner, J.1    Seiler, M.2    Walters, R.3    Kotin, R.M.4    Fulgeras, W.5    Davidson, B.L.6
  • 18
    • 0034992340 scopus 로고    scopus 로고
    • Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectors
    • Halbert C.L., Allen J.M., Miller A.D. Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectors. J. Virol 2001, 75:6615-6624.
    • (2001) J. Virol , vol.75 , pp. 6615-6624
    • Halbert, C.L.1    Allen, J.M.2    Miller, A.D.3
  • 20
    • 44349170706 scopus 로고    scopus 로고
    • Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection
    • Zincarelli C., Soltys S., Rengo G., Rabinowitz J.E. Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection. Mol. Ther 2008, 16:1073-1080.
    • (2008) Mol. Ther , vol.16 , pp. 1073-1080
    • Zincarelli, C.1    Soltys, S.2    Rengo, G.3    Rabinowitz, J.E.4
  • 21
    • 84898410131 scopus 로고    scopus 로고
    • Adeno-associated virus type 8 vector-mediated expression of siRNA targeting vascular endothelial growth factor efficiently inhibits neovascularization in a murine choroidal neovascularization model
    • Igarashi T., Miyake N., Fujimoto C., Yaguchi C., Iijima O., Shimada T., et al. Adeno-associated virus type 8 vector-mediated expression of siRNA targeting vascular endothelial growth factor efficiently inhibits neovascularization in a murine choroidal neovascularization model. Mol. Vis 2014, 20:488-496.
    • (2014) Mol. Vis , vol.20 , pp. 488-496
    • Igarashi, T.1    Miyake, N.2    Fujimoto, C.3    Yaguchi, C.4    Iijima, O.5    Shimada, T.6
  • 22
    • 84871243601 scopus 로고    scopus 로고
    • Correction of pathological accumulation of glycosaminoglycans in central nervous system and peripheral tissues of MPSIIIA mice through systemic AAV9 gene transfer
    • Ruzo A., Marco S., Garcia M., Villacampa P., Ribera A., Ayuso E., et al. Correction of pathological accumulation of glycosaminoglycans in central nervous system and peripheral tissues of MPSIIIA mice through systemic AAV9 gene transfer. Hum. Gene Ther 2012, 23:1237-1246.
    • (2012) Hum. Gene Ther , vol.23 , pp. 1237-1246
    • Ruzo, A.1    Marco, S.2    Garcia, M.3    Villacampa, P.4    Ribera, A.5    Ayuso, E.6
  • 23
    • 9644265332 scopus 로고    scopus 로고
    • Two novel adeno-associated viruses from cynomolgus monkey: pseudotyping characterization of capsid protein
    • Mori S., Wang L., Takeuchi T., Kanda T. Two novel adeno-associated viruses from cynomolgus monkey: pseudotyping characterization of capsid protein. Virol 2004, 330:375-383.
    • (2004) Virol , vol.330 , pp. 375-383
    • Mori, S.1    Wang, L.2    Takeuchi, T.3    Kanda, T.4
  • 24
    • 33847211798 scopus 로고    scopus 로고
    • Enhanced survival of the LINCL mouse following CLN2 gene transfer using the rh.10 rhesus macaque-derived adeno-associated virus vector
    • Sondhi D., Hackett N.R., Peterson D.A., Stratton J., Baad M., Travis K.M., et al. Enhanced survival of the LINCL mouse following CLN2 gene transfer using the rh.10 rhesus macaque-derived adeno-associated virus vector. Mol. Ther 2007, 15:481-491.
    • (2007) Mol. Ther , vol.15 , pp. 481-491
    • Sondhi, D.1    Hackett, N.R.2    Peterson, D.A.3    Stratton, J.4    Baad, M.5    Travis, K.M.6
  • 25
    • 38349168183 scopus 로고    scopus 로고
    • Adeno-associated virus type 12 (AAV12): a novel AAV serotype with sialic acid- and heparan sulfate proteoglycan-independent transduction activity
    • Schmidt M., Voutetakis A., Afione S., Zheng C., Mandikian D., Chiorini J.A. Adeno-associated virus type 12 (AAV12): a novel AAV serotype with sialic acid- and heparan sulfate proteoglycan-independent transduction activity. J. Virol 2008, 82:1399-1406.
    • (2008) J. Virol , vol.82 , pp. 1399-1406
    • Schmidt, M.1    Voutetakis, A.2    Afione, S.3    Zheng, C.4    Mandikian, D.5    Chiorini, J.A.6
  • 26
    • 79961032418 scopus 로고    scopus 로고
    • Several rAAV vectors efficiently cross the blood-brain barrier and transduce neurons and astrocytes in the neonatal mouse central nervous system
    • Zhang H., Yang B., Mu X., Ahmed S.S., Su Q., He R., et al. Several rAAV vectors efficiently cross the blood-brain barrier and transduce neurons and astrocytes in the neonatal mouse central nervous system. Mol. Ther 2011, 19:1440-1448.
    • (2011) Mol. Ther , vol.19 , pp. 1440-1448
    • Zhang, H.1    Yang, B.2    Mu, X.3    Ahmed, S.S.4    Su, Q.5    He, R.6
  • 27
    • 0029849257 scopus 로고    scopus 로고
    • Quantitative analysis of the packaging capacity of recombinant adeno-associated virus
    • Dong J.Y., Fan P.D., Frizzell R.A. Quantitative analysis of the packaging capacity of recombinant adeno-associated virus. Hum. Gene Ther 1996, 7:2101-2112.
    • (1996) Hum. Gene Ther , vol.7 , pp. 2101-2112
    • Dong, J.Y.1    Fan, P.D.2    Frizzell, R.A.3
  • 28
    • 0038805301 scopus 로고    scopus 로고
    • Immune responses to adeno-associated virus and its recombinant vectors
    • Sun J.Y., Anand-Jawa V., Chatterjee S., Wong K.K. Immune responses to adeno-associated virus and its recombinant vectors. Gene Ther 2003, 10:964-976.
    • (2003) Gene Ther , vol.10 , pp. 964-976
    • Sun, J.Y.1    Anand-Jawa, V.2    Chatterjee, S.3    Wong, K.K.4
  • 29
    • 0034882826 scopus 로고    scopus 로고
    • Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis
    • McCarty D.M., Monahan P.E., Samulski R.J. Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis. Gene Ther 2001, 8:1248-1254.
    • (2001) Gene Ther , vol.8 , pp. 1248-1254
    • McCarty, D.M.1    Monahan, P.E.2    Samulski, R.J.3
  • 30
    • 40549119871 scopus 로고    scopus 로고
    • Designer gene delivery vectors: molecular engineering and evolution of adeno-associated viral vectors for enhanced gene transfer
    • Kwon I., Schaffer D.V. Designer gene delivery vectors: molecular engineering and evolution of adeno-associated viral vectors for enhanced gene transfer. Pharm. Res 2008, 25:489-499.
    • (2008) Pharm. Res , vol.25 , pp. 489-499
    • Kwon, I.1    Schaffer, D.V.2
  • 31
    • 0021716589 scopus 로고
    • A human parvovirus, adeno-associated virus, as a eucaryotic vector: transient expression and encapsidation of the procaryotic gene for chloramphenicol acetyltransferase
    • Tratschin J.D., West M.H., Sandbank T., Carter B.J. A human parvovirus, adeno-associated virus, as a eucaryotic vector: transient expression and encapsidation of the procaryotic gene for chloramphenicol acetyltransferase. Mol. Cell. Biol 1984, 4:2072-2081.
    • (1984) Mol. Cell. Biol , vol.4 , pp. 2072-2081
    • Tratschin, J.D.1    West, M.H.2    Sandbank, T.3    Carter, B.J.4
  • 32
    • 0029898764 scopus 로고    scopus 로고
    • A phase I study of an adeno-associated virus-CFTR gene vector in adult CF patients with mild lung disease
    • Flotte T., Carter B., Conrad C., Guggino W., Reynolds T., Rosenstein B., et al. A phase I study of an adeno-associated virus-CFTR gene vector in adult CF patients with mild lung disease. Hum. Gene Ther 1996, 7:1145-1159.
    • (1996) Hum. Gene Ther , vol.7 , pp. 1145-1159
    • Flotte, T.1    Carter, B.2    Conrad, C.3    Guggino, W.4    Reynolds, T.5    Rosenstein, B.6
  • 33
    • 84879161464 scopus 로고    scopus 로고
    • II trial of adeno-associated virus-mediated alpha-glucosidase gene therapy to the diaphragm for chronic respiratory failure in Pompe disease: initial safety and ventilatory outcomes
    • Smith B.K., Collins S.W., Conlon T.J., Mah C.S., Lawson L.A., Martin A.D., et al. II trial of adeno-associated virus-mediated alpha-glucosidase gene therapy to the diaphragm for chronic respiratory failure in Pompe disease: initial safety and ventilatory outcomes. Hum. Gene Ther 2013, 24:630-640.
    • (2013) Hum. Gene Ther , vol.24 , pp. 630-640
    • Smith, B.K.1    Collins, S.W.2    Conlon, T.J.3    Mah, C.S.4    Lawson, L.A.5    Martin, A.D.6
  • 34
    • 84890054617 scopus 로고    scopus 로고
    • Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression
    • Mueller C., Chulay J.D., Trapnell B.C., Humphries M., Carey B., Sandhaus R.A., et al. Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression. J. Clin. Invest 2013, 123:5310-5318.
    • (2013) J. Clin. Invest , vol.123 , pp. 5310-5318
    • Mueller, C.1    Chulay, J.D.2    Trapnell, B.C.3    Humphries, M.4    Carey, B.5    Sandhaus, R.A.6
  • 35
    • 80155145248 scopus 로고    scopus 로고
    • Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing alpha1-antitrypsin: interim results
    • Flotte T.R., Trapnell B.C., Humphries M., Carey B., Calcedo R., Rouhani F., et al. Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing alpha1-antitrypsin: interim results. Hum. Gene Ther 2011, 22:1239-1247.
    • (2011) Hum. Gene Ther , vol.22 , pp. 1239-1247
    • Flotte, T.R.1    Trapnell, B.C.2    Humphries, M.3    Carey, B.4    Calcedo, R.5    Rouhani, F.6
  • 36
    • 78249253608 scopus 로고    scopus 로고
    • Sustained alpha-sarcoglycan gene expression after gene transfer in limb-girdle muscular dystrophy, type 2D
    • Mendell J.R., Rodino-Klapac L.R., Rosales X.Q., Coley B.D., Galloway G., Lewis S., et al. Sustained alpha-sarcoglycan gene expression after gene transfer in limb-girdle muscular dystrophy, type 2D. Ann. Neurol 2010, 68:629-638.
    • (2010) Ann. Neurol , vol.68 , pp. 629-638
    • Mendell, J.R.1    Rodino-Klapac, L.R.2    Rosales, X.Q.3    Coley, B.D.4    Galloway, G.5    Lewis, S.6
  • 37
    • 84896320924 scopus 로고    scopus 로고
    • Immune responses to intramuscular administration of alipogene tiparvovec (AAV1-LPL(S447X)) in a phase II clinical trial of lipoprotein lipase deficiency gene therapy
    • Ferreira V., Twisk J., Kwikkers K., Aronica E., Brisson D., Methot J., et al. Immune responses to intramuscular administration of alipogene tiparvovec (AAV1-LPL(S447X)) in a phase II clinical trial of lipoprotein lipase deficiency gene therapy. Hum. Gene Ther 2014, 25:180-188.
    • (2014) Hum. Gene Ther , vol.25 , pp. 180-188
    • Ferreira, V.1    Twisk, J.2    Kwikkers, K.3    Aronica, E.4    Brisson, D.5    Methot, J.6
  • 38
    • 60449107858 scopus 로고    scopus 로고
    • The pros and cons of immunomodulatory IL-10 gene therapy with recombinant AAV in a Cftr-/- -dependent allergy mouse model
    • Mueller C., Braag S.A., Martino A.T., Tang Q., Campbell-Thompson M., Flotte T.R. The pros and cons of immunomodulatory IL-10 gene therapy with recombinant AAV in a Cftr-/- -dependent allergy mouse model. Gene Ther 2009, 16:172-183.
    • (2009) Gene Ther , vol.16 , pp. 172-183
    • Mueller, C.1    Braag, S.A.2    Martino, A.T.3    Tang, Q.4    Campbell-Thompson, M.5    Flotte, T.R.6
  • 39
    • 84875698008 scopus 로고    scopus 로고
    • Muscle-directed anti-Abeta single-chain antibody delivery via AAV1 reduces cerebral Abeta load in an Alzheimer's disease mouse model
    • Yang J., Pattanayak A., Song M., Kou J., Taguchi H., Paul S., et al. Muscle-directed anti-Abeta single-chain antibody delivery via AAV1 reduces cerebral Abeta load in an Alzheimer's disease mouse model. J. Mol. Neurosci 2013, 49:277-288.
    • (2013) J. Mol. Neurosci , vol.49 , pp. 277-288
    • Yang, J.1    Pattanayak, A.2    Song, M.3    Kou, J.4    Taguchi, H.5    Paul, S.6
  • 40
    • 84897051037 scopus 로고    scopus 로고
    • Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial
    • MacLaren R.E., Groppe M., Barnard A.R., Cottriall C.L., Tolmachova T., Seymour L., et al. Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial. Lancet 2014, 383:1129-1137.
    • (2014) Lancet , vol.383 , pp. 1129-1137
    • MacLaren, R.E.1    Groppe, M.2    Barnard, A.R.3    Cottriall, C.L.4    Tolmachova, T.5    Seymour, L.6
  • 42
    • 77956262279 scopus 로고    scopus 로고
    • A phase I study of aromatic L-amino acid decarboxylase gene therapy for Parkinson's disease
    • Muramatsu S., Fujimoto K., Kato S., Mizukami H., Asari S., Ikeguchi K., et al. A phase I study of aromatic L-amino acid decarboxylase gene therapy for Parkinson's disease. Mol. Ther 2010, 18:1731-1735.
    • (2010) Mol. Ther , vol.18 , pp. 1731-1735
    • Muramatsu, S.1    Fujimoto, K.2    Kato, S.3    Mizukami, H.4    Asari, S.5    Ikeguchi, K.6
  • 43
    • 84878847875 scopus 로고    scopus 로고
    • Sustained mobilization of endogenous neural progenitors delays disease progression in a transgenic model of Huntington's disease
    • Benraiss A., Toner M.J., Xu Q., Bruel-Jungerman E., Rogers E.H., Wang F., et al. Sustained mobilization of endogenous neural progenitors delays disease progression in a transgenic model of Huntington's disease. Cell Stem Cell 2013, 12:787-799.
    • (2013) Cell Stem Cell , vol.12 , pp. 787-799
    • Benraiss, A.1    Toner, M.J.2    Xu, Q.3    Bruel-Jungerman, E.4    Rogers, E.H.5    Wang, F.6
  • 44
    • 78650918245 scopus 로고    scopus 로고
    • AAV4-mediated expression of IGF-1 and VEGF within cellular components of the ventricular system improves survival outcome in familial ALS mice
    • Dodge J.C., Treleaven C.M., Fidler J.A., Hester M., Haidet A., Handy C., et al. AAV4-mediated expression of IGF-1 and VEGF within cellular components of the ventricular system improves survival outcome in familial ALS mice. Mol. Ther 2010, 18:2075-2084.
    • (2010) Mol. Ther , vol.18 , pp. 2075-2084
    • Dodge, J.C.1    Treleaven, C.M.2    Fidler, J.A.3    Hester, M.4    Haidet, A.5    Handy, C.6
  • 45
    • 84895905784 scopus 로고    scopus 로고
    • Successful gene therapy in the RPGRIP1-deficient dog: a large model of cone-rod dystrophy
    • Lheriteau E., Petit L., Weber M., Le Meur G., Deschamps J.Y., Libeau L., et al. Successful gene therapy in the RPGRIP1-deficient dog: a large model of cone-rod dystrophy. Mol. Ther 2014, 22:265-277.
    • (2014) Mol. Ther , vol.22 , pp. 265-277
    • Lheriteau, E.1    Petit, L.2    Weber, M.3    Le Meur, G.4    Deschamps, J.Y.5    Libeau, L.6
  • 46
    • 84870581997 scopus 로고    scopus 로고
    • Hsp40 gene therapy exerts therapeutic effects on polyglutamine disease mice via a non-cell autonomous mechanism
    • Popiel H.A., Takeuchi T., Fujita H., Yamamoto K., Ito C., Yamane H., et al. Hsp40 gene therapy exerts therapeutic effects on polyglutamine disease mice via a non-cell autonomous mechanism. PLoS ONE 2012, 7:e51069.
    • (2012) PLoS ONE , vol.7 , pp. e51069
    • Popiel, H.A.1    Takeuchi, T.2    Fujita, H.3    Yamamoto, K.4    Ito, C.5    Yamane, H.6
  • 47
    • 84893735933 scopus 로고    scopus 로고
    • Therapeutic safety of high myocardial expression levels of the molecular inotrope S100A1 in a preclinical heart failure model
    • Weber C., Neacsu I., Krautz B., Schlegel P., Sauer S., Raake P., et al. Therapeutic safety of high myocardial expression levels of the molecular inotrope S100A1 in a preclinical heart failure model. Gene Ther 2014, 21:131-138.
    • (2014) Gene Ther , vol.21 , pp. 131-138
    • Weber, C.1    Neacsu, I.2    Krautz, B.3    Schlegel, P.4    Sauer, S.5    Raake, P.6
  • 48
    • 84886953461 scopus 로고    scopus 로고
    • Gene transfer of heme oxygenase-1 using an adeno-associated virus serotype 6 vector prolongs cardiac allograft survival
    • Evans J.M., Navarro S., Doki T., Stewart J.M., Mitsuhashi N., Kearns-Jonker M. Gene transfer of heme oxygenase-1 using an adeno-associated virus serotype 6 vector prolongs cardiac allograft survival. J. Transplant 2012, 2012:740653.
    • (2012) J. Transplant , vol.2012 , pp. 740653
    • Evans, J.M.1    Navarro, S.2    Doki, T.3    Stewart, J.M.4    Mitsuhashi, N.5    Kearns-Jonker, M.6
  • 49
    • 80455174006 scopus 로고    scopus 로고
    • Hepatorenal correction in murine glycogen storage disease type I with a double-stranded adeno-associated virus vector
    • Luo X., Hall G., Li S., Bird A., Lavin P.J., Winn M.P., et al. Hepatorenal correction in murine glycogen storage disease type I with a double-stranded adeno-associated virus vector. Mol. Ther 2011, 19:1961-1970.
    • (2011) Mol. Ther , vol.19 , pp. 1961-1970
    • Luo, X.1    Hall, G.2    Li, S.3    Bird, A.4    Lavin, P.J.5    Winn, M.P.6
  • 51
    • 67649871388 scopus 로고    scopus 로고
    • Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle
    • Anisimov A., Alitalo A., Korpisalo P., Soronen J., Kaijalainen S., Leppanen V.M., et al. Activated forms of VEGF-C and VEGF-D provide improved vascular function in skeletal muscle. Circ. Res 2009, 104:1302-1312.
    • (2009) Circ. Res , vol.104 , pp. 1302-1312
    • Anisimov, A.1    Alitalo, A.2    Korpisalo, P.3    Soronen, J.4    Kaijalainen, S.5    Leppanen, V.M.6
  • 52
    • 84927927157 scopus 로고    scopus 로고
    • Catalytic immunoglobulin gene delivery in a mouse model of Alzheimer's disease: prophylactic and therapeutic applications
    • Epub ahead of print
    • Kou J., Yang J., Lim J.E., Pattanayak A., Song M., Planque S., et al. Catalytic immunoglobulin gene delivery in a mouse model of Alzheimer's disease: prophylactic and therapeutic applications. Mol. Neurobiol 2014, Epub ahead of print. 10.1007/s12035-014-8691-z.
    • (2014) Mol. Neurobiol
    • Kou, J.1    Yang, J.2    Lim, J.E.3    Pattanayak, A.4    Song, M.5    Planque, S.6
  • 53
    • 84897573612 scopus 로고    scopus 로고
    • Effect of bortezomib on the efficacy of AAV9.SERCA2a treatment to preserve cardiac function in a rat pressure-overload model of heart failure
    • Chaanine A.H., Nonnenmacher M., Kohlbrenner E., Jin D., Kovacic J.C., Akar F.G., et al. Effect of bortezomib on the efficacy of AAV9.SERCA2a treatment to preserve cardiac function in a rat pressure-overload model of heart failure. Gene Ther 2014, 21:379-386.
    • (2014) Gene Ther , vol.21 , pp. 379-386
    • Chaanine, A.H.1    Nonnenmacher, M.2    Kohlbrenner, E.3    Jin, D.4    Kovacic, J.C.5    Akar, F.G.6
  • 54
    • 84878294979 scopus 로고    scopus 로고
    • MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors
    • Ganesan J., Ramanujam D., Sassi Y., Ahles A., Jentzsch C., Werfel S., et al. MiR-378 controls cardiac hypertrophy by combined repression of mitogen-activated protein kinase pathway factors. Circulation 2013, 127:2097-2106.
    • (2013) Circulation , vol.127 , pp. 2097-2106
    • Ganesan, J.1    Ramanujam, D.2    Sassi, Y.3    Ahles, A.4    Jentzsch, C.5    Werfel, S.6
  • 56
    • 84902976174 scopus 로고    scopus 로고
    • Prevention and reversal of severe mitochondrial cardiomyopathy by gene therapy in a mouse model of Friedreich's ataxia
    • Perdomini M., Belbellaa B., Monassier L., Reutenauer L., Messaddeq N., Cartier N., et al. Prevention and reversal of severe mitochondrial cardiomyopathy by gene therapy in a mouse model of Friedreich's ataxia. Nat. Med 2014, 20:542-547. 10.1038/nm.3510.
    • (2014) Nat. Med , vol.20 , pp. 542-547
    • Perdomini, M.1    Belbellaa, B.2    Monassier, L.3    Reutenauer, L.4    Messaddeq, N.5    Cartier, N.6
  • 57
    • 84896361627 scopus 로고    scopus 로고
    • Partial correction of the CNS lysosomal storage defect in a mouse model of juvenile neuronal ceroid lipofuscinosis by neonatal CNS administration of an adeno-associated virus Serotype rh.10 vector expressing the human CLN3 gene
    • Sondhi D., Scott E.C., Chen A., Hackett N.R., Wong A.M., Kubiak A., et al. Partial correction of the CNS lysosomal storage defect in a mouse model of juvenile neuronal ceroid lipofuscinosis by neonatal CNS administration of an adeno-associated virus Serotype rh.10 vector expressing the human CLN3 gene. Hum. Gene Ther 2014, 25:223-239.
    • (2014) Hum. Gene Ther , vol.25 , pp. 223-239
    • Sondhi, D.1    Scott, E.C.2    Chen, A.3    Hackett, N.R.4    Wong, A.M.5    Kubiak, A.6
  • 58
    • 70349843885 scopus 로고    scopus 로고
    • Oncolytic gene therapy combined with double suicide genes for human bile duct cancer in nude mouse models
    • Kojima Y., Honda K., Hamada H., Kobayashi N. Oncolytic gene therapy combined with double suicide genes for human bile duct cancer in nude mouse models. J. Surg. Res 2009, 157:e63-e70.
    • (2009) J. Surg. Res , vol.157 , pp. e63-e70
    • Kojima, Y.1    Honda, K.2    Hamada, H.3    Kobayashi, N.4
  • 59
    • 84872799939 scopus 로고    scopus 로고
    • The adeno-associated virus-mediated HSV-TK/GCV suicide system: a potential strategy for the treatment of bladder carcinoma
    • Pan J.G., Zhou X., Luo R., Han R.F. The adeno-associated virus-mediated HSV-TK/GCV suicide system: a potential strategy for the treatment of bladder carcinoma. Med. Oncol 2012, 29:1938-1947.
    • (2012) Med. Oncol , vol.29 , pp. 1938-1947
    • Pan, J.G.1    Zhou, X.2    Luo, R.3    Han, R.F.4
  • 60
    • 79953048095 scopus 로고    scopus 로고
    • Persistent anti-tumor effects via recombinant adeno-associated virus encoding herpes thymidine kinase gene monitored by PET-imaging
    • Kim J.Y., Kim J.H., Khim M., Lee H.S., Jung J.H., Moon D.H., et al. Persistent anti-tumor effects via recombinant adeno-associated virus encoding herpes thymidine kinase gene monitored by PET-imaging. Oncol. Rep 2011, 25:1263-1269.
    • (2011) Oncol. Rep , vol.25 , pp. 1263-1269
    • Kim, J.Y.1    Kim, J.H.2    Khim, M.3    Lee, H.S.4    Jung, J.H.5    Moon, D.H.6
  • 61
    • 68849090740 scopus 로고    scopus 로고
    • A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer
    • Trepel M., Stoneham C.A., Eleftherohorinou H., Mazarakis N.D., Pasqualini R., Arap W., et al. A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer. Mol. Cancer Ther 2009, 8:2383-2391.
    • (2009) Mol. Cancer Ther , vol.8 , pp. 2383-2391
    • Trepel, M.1    Stoneham, C.A.2    Eleftherohorinou, H.3    Mazarakis, N.D.4    Pasqualini, R.5    Arap, W.6
  • 62
    • 0038685423 scopus 로고    scopus 로고
    • Prodrugs for gene-directed enzyme-prodrug therapy (suicide gene therapy)
    • Denny W.A. Prodrugs for gene-directed enzyme-prodrug therapy (suicide gene therapy). J. Biomed. Biotechnol 2003, 2003:48-70.
    • (2003) J. Biomed. Biotechnol , vol.2003 , pp. 48-70
    • Denny, W.A.1
  • 63
    • 76749093047 scopus 로고    scopus 로고
    • The anti-glioma effect of suicide gene therapy using BMSC expressing HSV/TK combined with overexpression of Cx43 in glioma cells
    • Huang Q., Liu X.Z., Kang C.S., Wang G.X., Zhong Y., Pu P.Y. The anti-glioma effect of suicide gene therapy using BMSC expressing HSV/TK combined with overexpression of Cx43 in glioma cells. Cancer Gene Ther 2010, 17:192-202.
    • (2010) Cancer Gene Ther , vol.17 , pp. 192-202
    • Huang, Q.1    Liu, X.Z.2    Kang, C.S.3    Wang, G.X.4    Zhong, Y.5    Pu, P.Y.6
  • 65
    • 12144288999 scopus 로고    scopus 로고
    • The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins
    • Baranova A., Ivanov D., Petrash N., Pestova A., Skoblov M., Kelmanson I., et al. The mammalian pannexin family is homologous to the invertebrate innexin gap junction proteins. Genomics 2004, 83:706-716.
    • (2004) Genomics , vol.83 , pp. 706-716
    • Baranova, A.1    Ivanov, D.2    Petrash, N.3    Pestova, A.4    Skoblov, M.5    Kelmanson, I.6
  • 67
    • 85013312416 scopus 로고
    • Tumor angiogenesis: therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N. Engl. J. Med 1971, 285:1182-1186.
    • (1971) N. Engl. J. Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 68
    • 84866450580 scopus 로고    scopus 로고
    • AAV2-mediated gene transfer of VEGF-Trap with potent suppression of primary breast tumor growth and spontaneous pulmonary metastases by long-term expression
    • Lu L., Luo S.T., Shi H.S., Li M., Zhang H.L., He S.S., et al. AAV2-mediated gene transfer of VEGF-Trap with potent suppression of primary breast tumor growth and spontaneous pulmonary metastases by long-term expression. Oncol. Rep 2012, 28:1332-1338.
    • (2012) Oncol. Rep , vol.28 , pp. 1332-1338
    • Lu, L.1    Luo, S.T.2    Shi, H.S.3    Li, M.4    Zhang, H.L.5    He, S.S.6
  • 69
    • 84859053294 scopus 로고    scopus 로고
    • AAV-mediated human PEDF inhibits tumor growth and metastasis in murine colorectal peritoneal carcinomatosis model
    • Wu Q.J., Gong C.Y., Luo S.T., Zhang D.M., Zhang S., Shi H.S., et al. AAV-mediated human PEDF inhibits tumor growth and metastasis in murine colorectal peritoneal carcinomatosis model. BMC Cancer 2012, 12:129.
    • (2012) BMC Cancer , vol.12 , pp. 129
    • Wu, Q.J.1    Gong, C.Y.2    Luo, S.T.3    Zhang, D.M.4    Zhang, S.5    Shi, H.S.6
  • 70
    • 84863012319 scopus 로고    scopus 로고
    • AAV-mediated gene transfer of human pigment epithelium-derived factor inhibits Lewis lung carcinoma growth in mice
    • He S.S., Shi H.S., Yin T., Li Y.X., Luo S.T., Wu Q.J., et al. AAV-mediated gene transfer of human pigment epithelium-derived factor inhibits Lewis lung carcinoma growth in mice. Oncol. Rep 2012, 27:1142-1148.
    • (2012) Oncol. Rep , vol.27 , pp. 1142-1148
    • He, S.S.1    Shi, H.S.2    Yin, T.3    Li, Y.X.4    Luo, S.T.5    Wu, Q.J.6
  • 71
    • 77952427407 scopus 로고    scopus 로고
    • Adeno-associated virus-mediated delivery of kringle 5 of human plasminogen inhibits orthotopic growth of ovarian cancer
    • Bui Nguyen T.M., Subramanian I.V., Xiao X., Nguyen P., Ramakrishnan S. Adeno-associated virus-mediated delivery of kringle 5 of human plasminogen inhibits orthotopic growth of ovarian cancer. Gene Ther 2010, 17:606-615.
    • (2010) Gene Ther , vol.17 , pp. 606-615
    • Bui Nguyen, T.M.1    Subramanian, I.V.2    Xiao, X.3    Nguyen, P.4    Ramakrishnan, S.5
  • 72
    • 44449134974 scopus 로고    scopus 로고
    • Adeno-associated virus-mediated expression of kallistatin suppresses local and remote hepatocellular carcinomas
    • Tse L.Y., Sun X., Jiang H., Dong X., Fung P.W., Farzaneh F., et al. Adeno-associated virus-mediated expression of kallistatin suppresses local and remote hepatocellular carcinomas. J. Gene Med 2008, 10:508-517.
    • (2008) J. Gene Med , vol.10 , pp. 508-517
    • Tse, L.Y.1    Sun, X.2    Jiang, H.3    Dong, X.4    Fung, P.W.5    Farzaneh, F.6
  • 74
    • 34447643995 scopus 로고    scopus 로고
    • Generation of robust cytotoxic T lymphocytes against prostate specific antigen by transduction of dendritic cells using protein and recombinant adeno-associated virus
    • Mahadevan M., Liu Y., You C., Luo R., You H., Mehta J.L., et al. Generation of robust cytotoxic T lymphocytes against prostate specific antigen by transduction of dendritic cells using protein and recombinant adeno-associated virus. Cancer Immunol. Immunother 2007, 56:1615-1624.
    • (2007) Cancer Immunol. Immunother , vol.56 , pp. 1615-1624
    • Mahadevan, M.1    Liu, Y.2    You, C.3    Luo, R.4    You, H.5    Mehta, J.L.6
  • 75
    • 79953053268 scopus 로고    scopus 로고
    • Enhanced anti-glioblastoma activity of microglia by AAV2-mediated IL-12 through TRAIL and phagocytosis in vitro
    • Chiu T.L., Peng C.W., Wang M.J. Enhanced anti-glioblastoma activity of microglia by AAV2-mediated IL-12 through TRAIL and phagocytosis in vitro. Oncol. Rep 2011, 25:1373-1380.
    • (2011) Oncol. Rep , vol.25 , pp. 1373-1380
    • Chiu, T.L.1    Peng, C.W.2    Wang, M.J.3
  • 76
    • 66649116538 scopus 로고    scopus 로고
    • Immunotherapy: rAAV2 expressing interleukin-15 inhibits HeLa cell tumor growth in mice
    • Yiang G.T., Harn H.J., Yu Y.L., Hu S.C., Hung Y.T., Hsieh C.J., et al. Immunotherapy: rAAV2 expressing interleukin-15 inhibits HeLa cell tumor growth in mice. J. Biomed. Sci 2009, 16:47.
    • (2009) J. Biomed. Sci , vol.16 , pp. 47
    • Yiang, G.T.1    Harn, H.J.2    Yu, Y.L.3    Hu, S.C.4    Hung, Y.T.5    Hsieh, C.J.6
  • 77
    • 84863283367 scopus 로고    scopus 로고
    • Immunotherapy for SV40 T/t antigen-induced breast cancer by recombinant adeno-associated virus serotype 2 carrying interleukin-15 in mice
    • Yiang G.T., Chou P.L., Tsai H.F., Chen L.A., Chang W.J., Yu Y.L., et al. Immunotherapy for SV40 T/t antigen-induced breast cancer by recombinant adeno-associated virus serotype 2 carrying interleukin-15 in mice. Int. J. Mol. Med 2012, 29:809-814.
    • (2012) Int. J. Mol. Med , vol.29 , pp. 809-814
    • Yiang, G.T.1    Chou, P.L.2    Tsai, H.F.3    Chen, L.A.4    Chang, W.J.5    Yu, Y.L.6
  • 78
    • 84866006613 scopus 로고    scopus 로고
    • Human anti-CCR4 minibody gene transfer for the treatment of cutaneous T-cell lymphoma
    • Han T., Abdel-Motal U.M., Chang D.K., Sui J., Muvaffak A., Campbell J., et al. Human anti-CCR4 minibody gene transfer for the treatment of cutaneous T-cell lymphoma. PLoS ONE 2012, 7:e44455.
    • (2012) PLoS ONE , vol.7 , pp. e44455
    • Han, T.1    Abdel-Motal, U.M.2    Chang, D.K.3    Sui, J.4    Muvaffak, A.5    Campbell, J.6
  • 79
    • 67651091377 scopus 로고    scopus 로고
    • Controlling brain tumor growth by intraventricular administration of an AAV vector encoding IFN-beta
    • Meijer D.H., Maguire C.A., LeRoy S.G., Sena-Esteves M. Controlling brain tumor growth by intraventricular administration of an AAV vector encoding IFN-beta. Cancer Gene Ther 2009, 16:664-671.
    • (2009) Cancer Gene Ther , vol.16 , pp. 664-671
    • Meijer, D.H.1    Maguire, C.A.2    LeRoy, S.G.3    Sena-Esteves, M.4
  • 80
    • 84861728745 scopus 로고    scopus 로고
    • Antitumor effects of interferon-alpha on cell growth and metastasis in human nasopharyngeal carcinoma
    • Liu X., Lu J., He M.L., Li Z., Zhang B., Zhou L.H., et al. Antitumor effects of interferon-alpha on cell growth and metastasis in human nasopharyngeal carcinoma. Curr. Cancer Drug Targets 2012, 12:561-570.
    • (2012) Curr. Cancer Drug Targets , vol.12 , pp. 561-570
    • Liu, X.1    Lu, J.2    He, M.L.3    Li, Z.4    Zhang, B.5    Zhou, L.H.6
  • 81
    • 73449107465 scopus 로고    scopus 로고
    • Combined prophylactic and therapeutic intranasal vaccination against human papillomavirus type-16 using different adeno-associated virus serotype vectors
    • Nieto K., Kern A., Leuchs B., Gissmann L., Muller M., Kleinschmidt J.A. Combined prophylactic and therapeutic intranasal vaccination against human papillomavirus type-16 using different adeno-associated virus serotype vectors. Antiviral Ther 2009, 14:1125-1137.
    • (2009) Antiviral Ther , vol.14 , pp. 1125-1137
    • Nieto, K.1    Kern, A.2    Leuchs, B.3    Gissmann, L.4    Muller, M.5    Kleinschmidt, J.A.6
  • 82
    • 70349501955 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus encoding Epstein-Barr virus latent membrane proteins fused with heat shock protein as a potential vaccine for nasopharyngeal carcinoma
    • Pan J., Zhang Q., Zhou J., Ma D., Xiao X., Wang D.W. Recombinant adeno-associated virus encoding Epstein-Barr virus latent membrane proteins fused with heat shock protein as a potential vaccine for nasopharyngeal carcinoma. Mol. Cancer Ther 2009, 8:2754-2761.
    • (2009) Mol. Cancer Ther , vol.8 , pp. 2754-2761
    • Pan, J.1    Zhang, Q.2    Zhou, J.3    Ma, D.4    Xiao, X.5    Wang, D.W.6
  • 83
    • 84892687350 scopus 로고    scopus 로고
    • The anti-tumor effect and increased tregs infiltration mediated by rAAV-SLC vector
    • Li R., Hu H., Ma H., Chen L., Zhou B., Liu Y., et al. The anti-tumor effect and increased tregs infiltration mediated by rAAV-SLC vector. Mol. Biol. Rep 2013, 40:5615-5623.
    • (2013) Mol. Biol. Rep , vol.40 , pp. 5615-5623
    • Li, R.1    Hu, H.2    Ma, H.3    Chen, L.4    Zhou, B.5    Liu, Y.6
  • 84
    • 84873627359 scopus 로고    scopus 로고
    • Reconstructed adeno-associated virus with the extracellular domain of murine PD-1 induces antitumor immunity
    • Elhag O.A., Hu X.J., Wen-Ying Z., Li X., Yuan Y.Z., Deng L.F., et al. Reconstructed adeno-associated virus with the extracellular domain of murine PD-1 induces antitumor immunity. Asian Pac. J. Cancer Prev 2012, 13:4031-4036.
    • (2012) Asian Pac. J. Cancer Prev , vol.13 , pp. 4031-4036
    • Elhag, O.A.1    Hu, X.J.2    Wen-Ying, Z.3    Li, X.4    Yuan, Y.Z.5    Deng, L.F.6
  • 85
    • 84867878714 scopus 로고    scopus 로고
    • Efficient growth suppression and apoptosis in human laryngeal carcinoma cell line HEP-2 induced by an adeno-associated virus expressing human FAS ligand
    • Sun H., Liu Y., Bu D., Liu X., Norris J.S., Xiao S. Efficient growth suppression and apoptosis in human laryngeal carcinoma cell line HEP-2 induced by an adeno-associated virus expressing human FAS ligand. Head Neck 2012, 34:1628-1633.
    • (2012) Head Neck , vol.34 , pp. 1628-1633
    • Sun, H.1    Liu, Y.2    Bu, D.3    Liu, X.4    Norris, J.S.5    Xiao, S.6
  • 86
    • 84892815661 scopus 로고    scopus 로고
    • Adeno-associated virus-mediated expression of recombinant CBD-HepII polypeptide of human fibronectin inhibits metastasis of breast cancer
    • He Z.H., Lei Z., Zhen Y., Gong W., Huang B., Yuan Y., et al. Adeno-associated virus-mediated expression of recombinant CBD-HepII polypeptide of human fibronectin inhibits metastasis of breast cancer. Breast Cancer Res. Treat 2014, 143:33-45.
    • (2014) Breast Cancer Res. Treat , vol.143 , pp. 33-45
    • He, Z.H.1    Lei, Z.2    Zhen, Y.3    Gong, W.4    Huang, B.5    Yuan, Y.6
  • 87
    • 78049502563 scopus 로고    scopus 로고
    • Secretory expression of Par-4 SAC-HA2TAT following adeno-associated virus-mediated gene transfer induces apoptosis in HepG2 cells
    • Qin T.J., Ma W., Liu S.X., Yang G.X., Wang Q.Y., Zhao X.H. Secretory expression of Par-4 SAC-HA2TAT following adeno-associated virus-mediated gene transfer induces apoptosis in HepG2 cells. Mol. Med. Rep 2010, 3:749-757.
    • (2010) Mol. Med. Rep , vol.3 , pp. 749-757
    • Qin, T.J.1    Ma, W.2    Liu, S.X.3    Yang, G.X.4    Wang, Q.Y.5    Zhao, X.H.6
  • 88
    • 79951581625 scopus 로고    scopus 로고
    • Adeno-associated virus-mediated anti-DR5 chimeric antibody expression suppresses human tumor growth in nude mice
    • Lv F., Qiu Y., Zhang Y., Liu S., Shi J., Liu Y., et al. Adeno-associated virus-mediated anti-DR5 chimeric antibody expression suppresses human tumor growth in nude mice. Cancer Lett 2011, 302:119-127.
    • (2011) Cancer Lett , vol.302 , pp. 119-127
    • Lv, F.1    Qiu, Y.2    Zhang, Y.3    Liu, S.4    Shi, J.5    Liu, Y.6
  • 89
    • 77952224945 scopus 로고    scopus 로고
    • Adeno-associated virus harboring fusion gene NT4-ant-shepherdin induce cell death in human lung cancer cells
    • Xiaojiang T., Jinsong Z., Jiansheng W., Chengen P., Guangxiao Y., Quanying W. Adeno-associated virus harboring fusion gene NT4-ant-shepherdin induce cell death in human lung cancer cells. Cancer Invest 2010, 28:465-471.
    • (2010) Cancer Invest , vol.28 , pp. 465-471
    • Xiaojiang, T.1    Jinsong, Z.2    Jiansheng, W.3    Chengen, P.4    Guangxiao, Y.5    Quanying, W.6
  • 90
    • 34249027012 scopus 로고    scopus 로고
    • A novel glioblastoma cancer gene therapy using AAV-mediated long-term expression of human TERT C-terminal polypeptide
    • Ng S.S., Gao Y., Chau D.H., Li G.H., Lai L.H., Huang P.T., et al. A novel glioblastoma cancer gene therapy using AAV-mediated long-term expression of human TERT C-terminal polypeptide. Cancer Gene Ther 2007, 14:561-572.
    • (2007) Cancer Gene Ther , vol.14 , pp. 561-572
    • Ng, S.S.1    Gao, Y.2    Chau, D.H.3    Li, G.H.4    Lai, L.H.5    Huang, P.T.6
  • 91
    • 73449116411 scopus 로고    scopus 로고
    • Adeno-associated virus-delivered short hairpin-structured RNA for androgen receptor gene silencing induces tumor eradication of prostate cancer xenografts in nude mice: a preclinical study
    • Sun A., Tang J., Terranova P.F., Zhang X., Thrasher J.B., Li B. Adeno-associated virus-delivered short hairpin-structured RNA for androgen receptor gene silencing induces tumor eradication of prostate cancer xenografts in nude mice: a preclinical study. Int. J. Cancer 2010, 126:764-774.
    • (2010) Int. J. Cancer , vol.126 , pp. 764-774
    • Sun, A.1    Tang, J.2    Terranova, P.F.3    Zhang, X.4    Thrasher, J.B.5    Li, B.6
  • 92
    • 66449136951 scopus 로고    scopus 로고
    • Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
    • Kota J., Chivukula R.R., O'Donnell K.A., Wentzel E.A., Montgomery C.L., Hwang H.W., et al. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 2009, 137:1005-1017.
    • (2009) Cell , vol.137 , pp. 1005-1017
    • Kota, J.1    Chivukula, R.R.2    O'Donnell, K.A.3    Wentzel, E.A.4    Montgomery, C.L.5    Hwang, H.W.6
  • 93
    • 84878857050 scopus 로고    scopus 로고
    • Real-time monitoring of miRNA function in pancreatic cell lines using recombinant AAV-based miRNA Asensors
    • Chen J., Liu X., Chen X., Guo Z., Liu J., Hao J., et al. Real-time monitoring of miRNA function in pancreatic cell lines using recombinant AAV-based miRNA Asensors. PLoS ONE 2013, 8:e66315.
    • (2013) PLoS ONE , vol.8 , pp. e66315
    • Chen, J.1    Liu, X.2    Chen, X.3    Guo, Z.4    Liu, J.5    Hao, J.6
  • 94
    • 84875233197 scopus 로고    scopus 로고
    • Development of an anti-angiogenic therapeutic model combining scAAV2-delivered siRNAs and noninvasive photoacoustic imaging of tumor vasculature development
    • Ruan Q., Xi L., Boye S.L., Han S., Chen Z.J., Hauswirth W.W., et al. Development of an anti-angiogenic therapeutic model combining scAAV2-delivered siRNAs and noninvasive photoacoustic imaging of tumor vasculature development. Cancer Lett 2013, 332:120-129.
    • (2013) Cancer Lett , vol.332 , pp. 120-129
    • Ruan, Q.1    Xi, L.2    Boye, S.L.3    Han, S.4    Chen, Z.J.5    Hauswirth, W.W.6
  • 95
    • 78650989327 scopus 로고    scopus 로고
    • Knockdown of snail sensitizes pancreatic cancer cells to chemotherapeutic agents and irradiation
    • Zhang K., Jiao X., Liu X., Zhang B., Wang J., Wang Q., et al. Knockdown of snail sensitizes pancreatic cancer cells to chemotherapeutic agents and irradiation. Int. J. Mol. Sci 2010, 11:4891-4892.
    • (2010) Int. J. Mol. Sci , vol.11 , pp. 4891-4892
    • Zhang, K.1    Jiao, X.2    Liu, X.3    Zhang, B.4    Wang, J.5    Wang, Q.6
  • 96
    • 44149084623 scopus 로고    scopus 로고
    • AAV-mediated TRAIL gene expression driven by hTERT promoter suppressed human hepatocellular carcinoma growth in mice
    • Zhang Y., Ma H., Zhang J., Liu S., Liu Y., Zheng D. AAV-mediated TRAIL gene expression driven by hTERT promoter suppressed human hepatocellular carcinoma growth in mice. Life Sci 2008, 82:1154-1161.
    • (2008) Life Sci , vol.82 , pp. 1154-1161
    • Zhang, Y.1    Ma, H.2    Zhang, J.3    Liu, S.4    Liu, Y.5    Zheng, D.6
  • 97
    • 44449139974 scopus 로고    scopus 로고
    • Potent antitumor effect of TRAIL mediated by a novel adeno-associated viral vector targeting to telomerase activity for human hepatocellular carcinoma
    • Wang Y., Huang F., Cai H., Zhong S., Liu X., Tan W.S. Potent antitumor effect of TRAIL mediated by a novel adeno-associated viral vector targeting to telomerase activity for human hepatocellular carcinoma. J. Gene Med 2008, 10:518-526.
    • (2008) J. Gene Med , vol.10 , pp. 518-526
    • Wang, Y.1    Huang, F.2    Cai, H.3    Zhong, S.4    Liu, X.5    Tan, W.S.6
  • 98
    • 71549168917 scopus 로고    scopus 로고
    • Suppression of cancer growth in mice by adeno-associated virus vector-mediated IFN-beta expression driven by hTERT promoter
    • He L.F., Wang Y.G., Xiao T., Zhang K.J., Li G.C., Gu J.F., et al. Suppression of cancer growth in mice by adeno-associated virus vector-mediated IFN-beta expression driven by hTERT promoter. Cancer Lett 2009, 286:196-205.
    • (2009) Cancer Lett , vol.286 , pp. 196-205
    • He, L.F.1    Wang, Y.G.2    Xiao, T.3    Zhang, K.J.4    Li, G.C.5    Gu, J.F.6
  • 99
    • 32944476780 scopus 로고    scopus 로고
    • Oral adeno-associated virus-sTRAIL gene therapy suppresses human hepatocellular carcinoma growth in mice
    • Ma H., Liu Y., Liu S., Xu R., Zheng D. Oral adeno-associated virus-sTRAIL gene therapy suppresses human hepatocellular carcinoma growth in mice. Hepatology 2005, 42:1355-1363.
    • (2005) Hepatology , vol.42 , pp. 1355-1363
    • Ma, H.1    Liu, Y.2    Liu, S.3    Xu, R.4    Zheng, D.5
  • 100
    • 80052701163 scopus 로고    scopus 로고
    • Acquisition of selective antitumoral effects of recombinant adeno-associated virus by genetically inserting tumor-targeting peptides into capsid proteins
    • Lee H.S., Kim J.Y., Lee W.I., Kim S.J., Ko M.J., Jeong S., et al. Acquisition of selective antitumoral effects of recombinant adeno-associated virus by genetically inserting tumor-targeting peptides into capsid proteins. Oncol. Lett 2011, 2:1113-1119.
    • (2011) Oncol. Lett , vol.2 , pp. 1113-1119
    • Lee, H.S.1    Kim, J.Y.2    Lee, W.I.3    Kim, S.J.4    Ko, M.J.5    Jeong, S.6
  • 101
    • 84885430641 scopus 로고    scopus 로고
    • The efficacy of combination therapy using adeno-associated virus-mediated co-expression of apoptin and interleukin-24 on hepatocellular carcinoma
    • Yuan L., Zhao H., Zhang L., Liu X. The efficacy of combination therapy using adeno-associated virus-mediated co-expression of apoptin and interleukin-24 on hepatocellular carcinoma. Tumour Biol 2013, 34:3027-3034.
    • (2013) Tumour Biol , vol.34 , pp. 3027-3034
    • Yuan, L.1    Zhao, H.2    Zhang, L.3    Liu, X.4
  • 102
    • 84856290181 scopus 로고    scopus 로고
    • Potent antitumour activity of the combination of HSV-TK and endostatin armed oncolytic adeno-associated virus for bladder cancer in vitro and in vivo
    • Pan J.G., Zhou X., Zeng G.W., Han R.F. Potent antitumour activity of the combination of HSV-TK and endostatin armed oncolytic adeno-associated virus for bladder cancer in vitro and in vivo. J. Surg. Oncol 2012, 105:249-257.
    • (2012) J. Surg. Oncol , vol.105 , pp. 249-257
    • Pan, J.G.1    Zhou, X.2    Zeng, G.W.3    Han, R.F.4
  • 103
    • 84886403264 scopus 로고    scopus 로고
    • Potent antitumor activity of the combination of HSV-TK and endostatin by adeno-associated virus vector for bladder cancer in vivo
    • Pan J.G., Luo R.Q., Zhou X., Han R.F., Zeng G.W. Potent antitumor activity of the combination of HSV-TK and endostatin by adeno-associated virus vector for bladder cancer in vivo. Clin. Lab 2013, 59:1147-1158.
    • (2013) Clin. Lab , vol.59 , pp. 1147-1158
    • Pan, J.G.1    Luo, R.Q.2    Zhou, X.3    Han, R.F.4    Zeng, G.W.5
  • 104
    • 78649332347 scopus 로고    scopus 로고
    • The efficacy of combination therapy using adeno-associated virus-TRAIL targeting to telomerase activity and cisplatin in a mice model of hepatocellular carcinoma
    • Wang Y., Huang F., Cai H., Wu Y., He G., Tan W.S. The efficacy of combination therapy using adeno-associated virus-TRAIL targeting to telomerase activity and cisplatin in a mice model of hepatocellular carcinoma. J. Cancer Res. Clin. Oncol 2010, 136:1827-1837.
    • (2010) J. Cancer Res. Clin. Oncol , vol.136 , pp. 1827-1837
    • Wang, Y.1    Huang, F.2    Cai, H.3    Wu, Y.4    He, G.5    Tan, W.S.6
  • 105
    • 79551528437 scopus 로고    scopus 로고
    • Synergistic antitumor effect of AAV-mediated TRAIL expression combined with cisplatin on head and neck squamous cell carcinoma
    • Jiang M., Liu Z., Xiang Y., Ma H., Liu S., Liu Y., et al. Synergistic antitumor effect of AAV-mediated TRAIL expression combined with cisplatin on head and neck squamous cell carcinoma. BMC Cancer 2011, 11:54.
    • (2011) BMC Cancer , vol.11 , pp. 54
    • Jiang, M.1    Liu, Z.2    Xiang, Y.3    Ma, H.4    Liu, S.5    Liu, Y.6
  • 106
    • 79951515453 scopus 로고    scopus 로고
    • AAV-P125A-endostatin and paclitaxel treatment increases endoreduplication in endothelial cells and inhibits metastasis of breast cancer
    • Subramanian I.V., Devineni S., Ghebre R., Ghosh G., Joshi H.P., Jing Y., et al. AAV-P125A-endostatin and paclitaxel treatment increases endoreduplication in endothelial cells and inhibits metastasis of breast cancer. Gene Ther 2011, 18:145-154.
    • (2011) Gene Ther , vol.18 , pp. 145-154
    • Subramanian, I.V.1    Devineni, S.2    Ghebre, R.3    Ghosh, G.4    Joshi, H.P.5    Jing, Y.6
  • 107
    • 33646242264 scopus 로고    scopus 로고
    • Adeno-associated virus-mediated delivery of a mutant endostatin in combination with carboplatin treatment inhibits orthotopic growth of ovarian cancer and improves long-term survival
    • Subramanian I.V., Bui Nguyen T.M., Truskinovsky A.M., Tolar J., Blazar B.R., Ramakrishnan S. Adeno-associated virus-mediated delivery of a mutant endostatin in combination with carboplatin treatment inhibits orthotopic growth of ovarian cancer and improves long-term survival. Cancer Res 2006, 66:4319-4328.
    • (2006) Cancer Res , vol.66 , pp. 4319-4328
    • Subramanian, I.V.1    Bui Nguyen, T.M.2    Truskinovsky, A.M.3    Tolar, J.4    Blazar, B.R.5    Ramakrishnan, S.6
  • 108
    • 38149075849 scopus 로고    scopus 로고
    • The efficacy of combination therapy using adeno-associated virus - interferon beta and trichostatin A in vitro and in a murine model of neuroblastoma
    • discussion 182-173
    • Hamner J.B., Sims T.L., Cutshaw A., Dickson P.V., Rosati S., McGee M., et al. The efficacy of combination therapy using adeno-associated virus - interferon beta and trichostatin A in vitro and in a murine model of neuroblastoma. J. Pediatr. Surg 2008, 43:177-182. discussion 182-173.
    • (2008) J. Pediatr. Surg , vol.43 , pp. 177-182
    • Hamner, J.B.1    Sims, T.L.2    Cutshaw, A.3    Dickson, P.V.4    Rosati, S.5    McGee, M.6
  • 109
    • 79952222737 scopus 로고    scopus 로고
    • Adeno-associated virus-mediated survivin mutant Thr34Ala cooperates with oxaliplatin to inhibit tumor growth and angiogenesis in colon cancer
    • Xue Z., Sun P.H., Zhu L.M., Jiang S.H., Qiao M.M., Chi A.L., et al. Adeno-associated virus-mediated survivin mutant Thr34Ala cooperates with oxaliplatin to inhibit tumor growth and angiogenesis in colon cancer. Oncol. Rep 2011, 25:1039-1046.
    • (2011) Oncol. Rep , vol.25 , pp. 1039-1046
    • Xue, Z.1    Sun, P.H.2    Zhu, L.M.3    Jiang, S.H.4    Qiao, M.M.5    Chi, A.L.6
  • 110
    • 0037269104 scopus 로고    scopus 로고
    • Suicide gene therapy using AAV-HSVtk/ganciclovir in combination with irradiation results in regression of human head and neck cancer xenografts in nude mice
    • Kanazawa T., Mizukami H., Okada T., Hanazono Y., Kume A., Nishino H., et al. Suicide gene therapy using AAV-HSVtk/ganciclovir in combination with irradiation results in regression of human head and neck cancer xenografts in nude mice. Gene Ther 2003, 10:51-58.
    • (2003) Gene Ther , vol.10 , pp. 51-58
    • Kanazawa, T.1    Mizukami, H.2    Okada, T.3    Hanazono, Y.4    Kume, A.5    Nishino, H.6
  • 111
    • 84868146838 scopus 로고    scopus 로고
    • High-intensity focused ultrasound combined with herpes simplex virus thymidine kinase gene-loaded ultrasound-targeted microbubbles improved the survival of rabbits with VX(2) liver tumor
    • Zhou S.J., Li S.W., Wang J.J., Liu Z.J., Yin G.B., Gong J.P., et al. High-intensity focused ultrasound combined with herpes simplex virus thymidine kinase gene-loaded ultrasound-targeted microbubbles improved the survival of rabbits with VX(2) liver tumor. J. Gene Med 2012, 14:570-579.
    • (2012) J. Gene Med , vol.14 , pp. 570-579
    • Zhou, S.J.1    Li, S.W.2    Wang, J.J.3    Liu, Z.J.4    Yin, G.B.5    Gong, J.P.6
  • 112
    • 0034050904 scopus 로고    scopus 로고
    • Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector
    • Kay M.A., Manno C.S., Ragni M.V., Larson P.J., Couto L.B., McClelland A., et al. Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector. Nat. Genet 2000, 24:257-261.
    • (2000) Nat. Genet , vol.24 , pp. 257-261
    • Kay, M.A.1    Manno, C.S.2    Ragni, M.V.3    Larson, P.J.4    Couto, L.B.5    McClelland, A.6
  • 113
    • 33644820684 scopus 로고    scopus 로고
    • Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
    • Manno C.S., Pierce G.F., Arruda V.R., Glader B., Ragni M., Rasko J.J., et al. Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response. Nat. Med 2006, 12:342-347.
    • (2006) Nat. Med , vol.12 , pp. 342-347
    • Manno, C.S.1    Pierce, G.F.2    Arruda, V.R.3    Glader, B.4    Ragni, M.5    Rasko, J.J.6
  • 114
    • 0013442744 scopus 로고    scopus 로고
    • AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B
    • Manno C.S., Chew A.J., Hutchison S., Larson P.J., Herzog R.W., Arruda V.R., et al. AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B. Blood 2003, 101:2963-2972.
    • (2003) Blood , vol.101 , pp. 2963-2972
    • Manno, C.S.1    Chew, A.J.2    Hutchison, S.3    Larson, P.J.4    Herzog, R.W.5    Arruda, V.R.6
  • 115
    • 84859198455 scopus 로고    scopus 로고
    • Factor IX expression in skeletal muscle of a severe hemophilia B patient 10 years after AAV-mediated gene transfer
    • Buchlis G., Podsakoff G.M., Radu A., Hawk S.M., Flake A.W., Mingozzi F., et al. Factor IX expression in skeletal muscle of a severe hemophilia B patient 10 years after AAV-mediated gene transfer. Blood 2012, 119:3038-3041.
    • (2012) Blood , vol.119 , pp. 3038-3041
    • Buchlis, G.1    Podsakoff, G.M.2    Radu, A.3    Hawk, S.M.4    Flake, A.W.5    Mingozzi, F.6
  • 116
    • 70349481529 scopus 로고    scopus 로고
    • Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy
    • Brantly M.L., Chulay J.D., Wang L., Mueller C., Humphries M., Spencer L.T., et al. Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy. Proc. Natl. Acad. Sci. U.S.A. 2009, 106:16363-16368.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 16363-16368
    • Brantly, M.L.1    Chulay, J.D.2    Wang, L.3    Mueller, C.4    Humphries, M.5    Spencer, L.T.6
  • 117
    • 41949110690 scopus 로고    scopus 로고
    • Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial
    • Marks W.J., Ostrem J.L., Verhagen L., Starr P.A., Larson P.S., Bakay R.A., et al. Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2-neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial. Lancet Neurol 2008, 7:400-408.
    • (2008) Lancet Neurol , vol.7 , pp. 400-408
    • Marks, W.J.1    Ostrem, J.L.2    Verhagen, L.3    Starr, P.A.4    Larson, P.S.5    Bakay, R.A.6
  • 118
    • 84879086501 scopus 로고    scopus 로고
    • Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patients
    • Bartus R.T., Baumann T.L., Siffert J., Herzog C.D., Alterman R., Boulis N., et al. Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patients. Neurology 2013, 80:1698-1701.
    • (2013) Neurology , vol.80 , pp. 1698-1701
    • Bartus, R.T.1    Baumann, T.L.2    Siffert, J.3    Herzog, C.D.4    Alterman, R.5    Boulis, N.6
  • 120
    • 84855611189 scopus 로고    scopus 로고
    • Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years
    • Jacobson S.G., Cideciyan A.V., Ratnakaram R., Heon E., Schwartz S.B., Roman A.J., et al. Gene therapy for leber congenital amaurosis caused by RPE65 mutations: safety and efficacy in 15 children and adults followed up to 3 years. Arch. Ophthalmol 2012, 130:9-24.
    • (2012) Arch. Ophthalmol , vol.130 , pp. 9-24
    • Jacobson, S.G.1    Cideciyan, A.V.2    Ratnakaram, R.3    Heon, E.4    Schwartz, S.B.5    Roman, A.J.6
  • 121
    • 84871194317 scopus 로고    scopus 로고
    • Clinical safety of induced CTL infusion through recombinant adeno-associated virus-transfected dendritic cell vaccination in Chinese cancer patients
    • Di L., Zhu Y., Jia J., Yu J., Song G., Zhang J., et al. Clinical safety of induced CTL infusion through recombinant adeno-associated virus-transfected dendritic cell vaccination in Chinese cancer patients. Clin. Transl. Oncol 2012, 14:675-681.
    • (2012) Clin. Transl. Oncol , vol.14 , pp. 675-681
    • Di, L.1    Zhu, Y.2    Jia, J.3    Yu, J.4    Song, G.5    Zhang, J.6
  • 122
    • 67749084439 scopus 로고    scopus 로고
    • Local delivery of a recombinant adenoassociated vector containing a tumour necrosis factor alpha antagonist gene in inflammatory arthritis: a phase 1 dose-escalation safety and tolerability study
    • Mease P.J., Hobbs K., Chalmers A., El-Gabalawy H., Bookman A., Keystone E., et al. Local delivery of a recombinant adenoassociated vector containing a tumour necrosis factor alpha antagonist gene in inflammatory arthritis: a phase 1 dose-escalation safety and tolerability study. Ann. Rheum. Dis 2009, 68:1247-1254.
    • (2009) Ann. Rheum. Dis , vol.68 , pp. 1247-1254
    • Mease, P.J.1    Hobbs, K.2    Chalmers, A.3    El-Gabalawy, H.4    Bookman, A.5    Keystone, E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.